Gene GL50803_17378 (G.lamblia)

GL50803_17378

Species: G.lamblia
Alias: GL50803_17378, GK050
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Other-GL1

Sequence

Name Sequence Type Origin Length Description Download
GL50803_17378.AA Protein None 2093 None Fasta, JSON
GL50803_17378.kin_dom Protein Kinase Domain None 232 None Fasta, JSON

Protein domain

Protein domains of GL50803_17378.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_17378.AA CAMK 73-304 13 8e-19 56.62 In-house 1-218 (425) Show / Hide 
Range on Protein: 73-304
Range on HMM: 1-218/425
Sequence Identity: 13% (43 aa)

QIGKGSYADVYTAENTVLR------------KTFVLRMVDR----------------IRLAKTLG----TQEAADKFLWSAASLMDRLQ-------HPNV
..|.||.. |. ....               . .   ..|.                |.  |. .    ...   |.. .  ..| .||       |||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLYEVFF------NLLVVPTPYLKQEDVNTSAPTRMLNAGVIYSNFGGLFSSSQNLTVDSLHLHVSTSFSRPNKTITYNMVKGILSPTHLGQIFDVNGT
..||||.       |     |                                                                               
IKLYEVYEDPHYFKN-----T-------------------------------------------------------------------------------

SAIRPPDDIDSY-NNK--------FIYVI----ERCHMKDL----------SSNL------------KTLSLRDIVLIFYQIAYGLEYLHSLLIVHHDIK
        .| | . .        ..| .    | |   .|           ..             . .. |.   .| ||. ...|.||. ||| |.|
--------ND-YET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLK

LENVLIDYNDNS
.||.|.|.|...
PENILLDDNNDD
Kinase GL50803_17378.AA CAMKL 270-303 52 7.7e-12 33.92 In-house 132-165 (297) Show / Hide 
Range on Protein: 270-303
Range on HMM: 132-165/297
Sequence Identity: 52% (18 aa)

IFYQIAYGLEYLHSLLIVHHDIKLENVLIDYNDN
.| ||  ...|.||. ||| |||.||.|.|.|.|
YFRQIVSAVNYCHSHGIVHRDIKPENILLDENGN
Kinase GL50803_17378.AA AMPK 271-303 54 2.5e-11 29.94 In-house 106-138 (254) Show / Hide 
Range on Protein: 271-303
Range on HMM: 106-138/254
Sequence Identity: 54% (18 aa)

FYQIAYGLEYLHSLLIVHHDIKLENVLIDYNDN
| ||  |.||.| . ||| | |.||.|.|.| |
FQQIISGVEYCHRHMIVHRDLKPENLLLDHNKN
Kinase GL50803_17378.AA Ciliate-E2-Unclassified 235-301 26 3.7e-11 34.96 In-house 88-180 (352) Show / Hide 
Range on Protein: 235-301
Range on HMM: 88-180/352
Sequence Identity: 26% (25 aa)

DIDSYNNKFIYVIERCHMKDLSSNLKT--------------------LSLRDIV-----LIFYQIAYGLEYLHSLL-IVHHDIKLENVLIDYN
...   .... | | |  .||.  .|                     .. . ..      .|.||  ||||||. . |.| |||.||.|.| |
YCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNN
Kinase GL50803_17378.AA MARK 270-303 55 1.3e-10 31.05 In-house 109-144 (262) Show / Hide 
Range on Protein: 270-303
Range on HMM: 109-144/262
Sequence Identity: 55% (20 aa)

IFYQIAYGLEYLHSLLIVHHDIKLENVLIDYND--N
|| || ....|.||  ||| |||.||.||| |   |
IFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHN
Kinase GL50803_17378.AA Pkinase 236-303 34 1.9e-10 38.0 Pfam 66-146 (293) Show / Hide 
Range on Protein: 236-303
Range on HMM: 66-146/293
Sequence Identity: 34% (28 aa)

IDSY-NNKFIY-VIERCHMK----DLS-----SNLKTL--SLRDIVLIFYQIAYGLEYLHSLLIVHHDIKLENVLIDYNDN
.|.. ... || | | | .     ||.     .. ...  | ...  ..|||. ||||.||  |.| |.|.||.||| |..
YDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGH
Kinase GL50803_17378.AA CAMKL 903-975 25 2.4e-10 29.08 In-house 212-297 (297) Show / Hide 
Range on Protein: 903-975
Range on HMM: 212-297/297
Sequence Identity: 25% (22 aa)

YMGMPSDVWQFGVALYSVLIGKHR--------------ELPLQRSSEEAMQ-ISTHLSLLLADLLCGLLAPSPMQRYTMVEVVNHPFF
| | . |.|  || ||  . |.                .| ..  .   .  |  |.|  . ||. ..| . |..|.|. ...|||..
YDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase GL50803_17378.AA Ciliate-E2 240-298 28 7e-10 30.09 In-house 106-194 (365) Show / Hide 
Range on Protein: 240-298
Range on HMM: 106-194/365
Sequence Identity: 28% (25 aa)

NNKFIYVIERCHMKDLSSNLK--------------TLSLRDIVLIFYQIAY---------------GLEYLHSLL-IVHHDIKLENVLI
.|.. .| | |  .|| . .|               .... |  |..||..               .||||||   |.| |||.||.|.
DNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF
Kinase GL50803_17378.AA ULK 260-302 39 4.3e-09 28.47 In-house 121-163 (324) Show / Hide 
Range on Protein: 260-302
Range on HMM: 121-163/324
Sequence Identity: 39% (17 aa)

KTLSLRDIVLIFYQIAYGLEYLHSLLIVHHDIKLENVLIDYND
|.||   .. .|.||. |. .||.  |.| |||..| ||  ..
KRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQ
Kinase GL50803_17378.AA AMPK 942-975 38 7.2e-09 22.53 In-house 221-254 (254) Show / Hide 
Range on Protein: 942-975
Range on HMM: 221-254/254
Sequence Identity: 38% (13 aa)

THLSLLLADLLCGLLAPSPMQRYTMVEVVNHPFF
..||   .||....| . ||.|.|  ...|||.|
KFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase GL50803_17378.AA ULK 240-302 29 1.2e-08 26.45 In-house 91-167 (329) Show / Hide 
Range on Protein: 240-302
Range on HMM: 91-167/329
Sequence Identity: 29% (23 aa)

N-NKFIYVIERCHMKDLSSNLK-------------TLSLRDIVLIFYQIAYGLEYLHSLLIVHHDIKLENVLIDYND
| | .  . | |   ||.. .|             .||   .. .|.||. |. .||.  |.| |||..|.||. ..
NHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQ
Kinase GL50803_17378.AA CAMK 941-975 28 1.8e-08 22.67 In-house 392-425 (425) Show / Hide 
Range on Protein: 941-975
Range on HMM: 392-425/425
Sequence Identity: 28% (10 aa)

STHLSLLLADLLCGLLAPSPMQRYTMVEVVNHPFF
. ..|    ||....| . | .|.|  .. |||..
H-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_17378.AA PLK 942-975 33 2.7e-08 23.23 In-house 223-258 (258) Show / Hide 
Range on Protein: 942-975
Range on HMM: 223-258/258
Sequence Identity: 33% (12 aa)

TH--LSLLLADLLCGLLAPSPMQRYTMVEVVNHPFF
.|  .|  ..||.  .| . | .|.|. .. .||||
EHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase GL50803_17378.AA S_TKc 68-975 4 4.3e-08 -58.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 68-975
Range on HMM: 1-231/231
Sequence Identity: 4% (43 aa)

YKLHNQIGKGSYADVYTAENTVLRKTFVLRMVDRIRLAKTLGTQEAADKFLWSAASLMDRLQHPNVVRLYEVFFNLLVVPTPYLKQEDVNTSAPTRMLNA
|.....||||... || . ..   . . . ...                                                                   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------------------------------------------------

GVIYSNFGGLFSSSQNLTVDSLHLHVSTSFSRPNKTITYNMVKGILSPTHLGQIFDVNGTSAIRPPDDIDSYNNKFIYVIERCHM--KDLSSNLKT----
                                 .     .. |      .. ...||  .             ...  | | |     || . .|     
--------------------------------EHIRREIQILKK--HHPNIVKLYDVFQD-------------DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LSLRDIVLIFYQIAYGLEYLHSLLIVHHDIKLENVLIDYNDN---------------------------SPSH--------------SVTSEKPY
     ..  ..  ..|||. .|||.||. |.| |.| ||.|.|   .                           . ..               .. . |.
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPF

KSSLMYGIDLSNLYNLCSSLDTNNSDPDSIKCLRTWIQPFKPATPEFESPCPCTQQPNAAKTTTQYEHDPFSSTKRSLAAKSKPKVCRSTNADFSASSCN
        ..  .....                                                                                   
P-------QMQMMFKKIG----------------------------------------------------------------------------------

KHLIPPISLGAYDSVETILDTSVTSLEFAKIAPFYIYYSLIFSSQFDSTNRVAFEHAIKRSNINTYFLVAKLSDFDTAKDLSVHGKVLPSLQDLLGKIVH
                                                                                                    
----------------------------------------------------------------------------------------------------

ELIKVLIDVFTDNWSSLLTNFDFLDAFLEDFFFSTIRYEPDSHQPNILHTDYYVSCENLDKLRPKTKIFGGTNELKSFLTNSSKCGHLQETFTLSTSSSS
                                                                                                    
----------------------------------------------------------------------------------------------------

ELSFAKSTFCTDTTERFFVPDQTTSDLILPASMTPNDIEICSSPVSSTTQFITTLTDENQPLVCSDNESSSDSQLLDNMGQCHSHGADGANLLDTRNQET
                                                                                                    
----------------------------------------------------------------------------------------------------

SCSTLEKNGPVLLSDIQTNTSTYSSPSHILHCALNLTSKALTFNNLQRHDASSKSFARRLPRVHKASNFSFSQVVLSRKSSSTRRLYLHHVIRYLNKLLI
                                                                                                    
----------------------------------------------------------------------------------------------------

SDMQPQVFQDFYFLLELLNTYFTSSIFEDKLAERLTVLFSSSEFICHHPLSRHVFPAYLSSIAGTRQCMPPESLRVWNTPSAATPNLYMGMPSDVWQFGV
                                                                                                    
----------------------------------------------------------------------------------------------------

ALYSVLIGKHRELPLQRSSEEAMQISTHLSLLLADLLCGLLAPSPMQRYTMVEVVN-------HPFF
                             |  . |.....|   | .|.|  |. .       ||.|
-----------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_17378.AA Ciliate-E2a 273-304 41 6.3e-08 19.44 In-house 109-142 (275) Show / Hide 
Range on Protein: 273-304
Range on HMM: 109-142/275
Sequence Identity: 41% (14 aa)

QIAY-GLEYLHSLLIVHHDIKLENVLID-YNDNS
|. . ||.|.|.. |.| |.|.||.|..  . ||
QLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNS
Kinase GL50803_17378.AA Ciliate-E2 68-140 16 6.6e-08 23.2 In-house 1-101 (365) Show / Hide 
Range on Protein: 68-140
Range on HMM: 1-101/365
Sequence Identity: 16% (17 aa)

YKLHNQIGKGSYADVYTAEN----------------------------TVLRKTFVLRMVDRIRLAKTLGT-----QEAADKFLWSAASLMDRLQHPNVV
||....||.|....|| ...                             .  |..  ...  |   . .       .    |..    ... .|.|||..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFY----KKI-NEKNILEQLNHPNII

RLYEVF
..||.|
KMYECF
Kinase GL50803_17378.AA MARK 940-975 33 1.1e-07 21.33 In-house 227-262 (262) Show / Hide 
Range on Protein: 940-975
Range on HMM: 227-262/262
Sequence Identity: 33% (12 aa)

ISTHLSLLLADLLCGLLAPSPMQRYTMVEVVNHPFF
| .|.|  . .|.. || . |..| |. |...||..
IPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase GL50803_17378.AA Pkinase 865-975 18 5.2e-07 25.86 Pfam 158-293 (293) Show / Hide 
Range on Protein: 865-975
Range on HMM: 158-293/293
Sequence Identity: 18% (27 aa)

LSR---HVFPAYLSSIAGTRQCMPPESLRVWNTPSAATPNLYMGMPSDVWQFGVALYSVLIGKHRELPLQRS-----------SEEAMQISTHLS-----
|..   .     .....||.  |.|| .|          . | | ..|.| .|. || .| |.   .| . .            .. |.  .| .     
LAKQFDY-NNS-MTTFCGTPWYMAPEVIR---------GGQYYGPKVDMWSCGCILYEMLCGR---PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWC

--------------------LLLADLLCGLLAPSPMQRYTMVEVVNHPFF
                      . |.....|.. | .|.|  ....||.|
SISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase GL50803_17378.AA Ciliate-E2a 68-86 47 7.4e-07 16.25 In-house 1-19 (275) Show / Hide 
Range on Protein: 68-86
Range on HMM: 1-19/275
Sequence Identity: 47% (9 aa)

YKLHNQIGKGSYADVYTAE
||....||||... || |.
YKFIKKIGKGNFGSVYLAQ
Kinase GL50803_17378.AA Ciliate-E2 908-975 23 3e-06 17.36 In-house 277-365 (365) Show / Hide 
Range on Protein: 908-975
Range on HMM: 277-365/365
Sequence Identity: 23% (21 aa)

SDVWQFGVALYSVLIGKH--RELPLQRSSEEAMQ--------------ISTHLSLLLADLLCG----LLAPSPMQRYT-MVEVVNHPFF
.|.| .|| ||  | ||.   .  .|   .   .              .  ..|.   ||.      .|   | .|.| . .. |||.|
CDIWSLGVILYEMLFGKPPFQQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_17378.AA TyrKc 68-476 10 5e-06 -125.33 SMART 1-280 (280) Show / Hide 
Range on Protein: 68-476
Range on HMM: 1-280/280
Sequence Identity: 10% (52 aa)

YKLHNQIGKGSYADVYTAENTVLRKTFVLRMVDRIRLAKTLGTQEAADKFLWSAASLMDRL--QHPNVVRLYEVFF---------NLLVVPTPYLKQEDV
 .|  ..| | .  || .. .            .    |.|        |. . |..| .|  .|||.|||| |             | . . | .  | 
ITLGKKLGEGAFGEVYKGTWK------------IQVAVKMLKEDA-REDFM-REARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

N----TSAPTRMLNAGVIYSNFGGLFSSSQNLTVDSLHLHVSTSFSRPNKTITYNMVKGILSPTHLGQIFDVNGTSAIRPPDDIDSYNNKFIYVIERCHM
.     . |.                                                                                          
KDYLRKHRPK------------------------------------------------------------------------------------------

KDLSSNLKTLSLRDIVLIFYQIAYGLEYLHSLLIVHHDIKLENVLIDYND-----------NSPSH-------SVTS------EK---PYK-------SS
         |...| . . .||| | |||||  ..| |.   |.|.. |            .  ..       .. .      .|   |..         
---------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

L---------MYGIDLSNLYNLCSSLDTN-----NSDPDSIKCLRTWIQPFKPATPEFE-SPCPCTQQPNAAKTTTQYEHDPFSSTKRSLAAKSKPKVCR
          ..|. .  .. .. .   .      |. . |.....   . .|. .. . |                                       
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMS---------------------------------------

STNADFSASSCNKHLIPPISLGAYDSVETILDTSVTSLEFAKIAPFYIYYSLIFSS-QFDSTNRVAFEHAIKRS
                                       |  ..|  .|  .. .  ..|  .|  |.  ... 
---------------------------------------F-VCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase GL50803_17378.AA PLK 270-301 46 7e-06 15.26 In-house 105-136 (258) Show / Hide 
Range on Protein: 270-301
Range on HMM: 105-136/258
Sequence Identity: 46% (15 aa)

IFYQIAYGLEYLHSLLIVHHDIKLENVLIDYN
. |||. ||.|||.  |.| |.|| |.... |
YMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDN
Kinase GL50803_17378.AA ULK 68-140 24 1.2e-05 15.8 In-house 1-87 (329) Show / Hide 
Range on Protein: 68-140
Range on HMM: 1-87/329
Sequence Identity: 24% (22 aa)

YKLHNQIGKGSYADVYTAENTVLR----KTFVLRMVDRIRLAKTL----GTQEAADKFLWSAASLMDRL--------QHPNVVRLYEVF
| |....||||.. || ..|        . ..  |.|.  . . .    |  . . ..| .   .| .|        .|||.|.||..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEG--QYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWF
Kinase GL50803_17378.AA Ciliate-E2-Unclassified 929-975 25 1.6e-05 15.1 In-house 302-352 (352) Show / Hide 
Range on Protein: 929-975
Range on HMM: 302-352/352
Sequence Identity: 25% (13 aa)

PLQRSSEEA----MQISTHLSLLLADLLCGLLAPSPMQRYTMVEVVNHPFF
..| ....     ...| .   .. |||. .|   | .|.|. .. |||.|
NIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_17378.AA CAMKL 122-143 27 4.4e-05 11.99 In-house 63-98 (297) Show / Hide 
Range on Protein: 122-143
Range on HMM: 63-98/297
Sequence Identity: 27% (10 aa)

ASLMDRLQ---HPNVVRLYEVF-----------FNL
...| .|.   |||...||||.           ..|
IQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYL
Kinase GL50803_17378.AA Pkinase 68-140 30 5.5e-05 18.7 Pfam 1-69 (293) Show / Hide 
Range on Protein: 68-140
Range on HMM: 1-69/293
Sequence Identity: 30% (22 aa)

YKLHNQIGKGSYADVYTAENTVLRKTFVLRMVDRIRLAKTLGTQEAADKFLWSAASLMDRLQHPNVVRLYEVF
|... .||.||.. || . .   .|....     |.. ..   .. ..  | | ...| ||.|||.||||..|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKI---IKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWF
Kinase GL50803_17378.AA ULK 68-87 42 6.7e-05 13.39 In-house 1-21 (324) Show / Hide 
Range on Protein: 68-87
Range on HMM: 1-21/324
Sequence Identity: 42% (9 aa)

YKLHNQIGKGSYA-DVYTAEN
| |....||||..  || ..|
YCLNHCLGKGSFGVKVYKGRN
Kinase GL50803_17378.AA Ciliate-E2a 950-975 38 6.7e-05 10.38 In-house 250-275 (275) Show / Hide 
Range on Protein: 950-975
Range on HMM: 250-275/275
Sequence Identity: 38% (10 aa)

DLLCGLLAPSPMQRYTMVEVVNHPFF
||. ..| . | .|.|  .  |||.|
DLMKKMLEKDPKKRITAQQALNHPWF
Kinase GL50803_17378.AA Ciliate-E2-Unclassified 68-87 40 8.6e-05 12.57 In-house 1-20 (352) Show / Hide 
Range on Protein: 68-87
Range on HMM: 1-20/352
Sequence Identity: 40% (8 aa)

YKLHNQIGKGSYADVYTAEN
||.. |||.|....|| ...
YKIIKQIGQGGFGKVYKCQH
Kinase GL50803_17378.AA CAMKL 68-93 26 0.000363 9.03 In-house 1-26 (297) Show / Hide 
Range on Protein: 68-93
Range on HMM: 1-26/297
Sequence Identity: 26% (7 aa)

YKLHNQIGKGSYADVYTAENTVLRKT
|..  ..||||.. |  |... . ..
YRIGKTLGKGSFGKVKLATHIRTTGE
Kinase GL50803_17378.AA MARK 68-85 55 0.000528 9.17 In-house 1-18 (262) Show / Hide 
Range on Protein: 68-85
Range on HMM: 1-18/262
Sequence Identity: 55% (10 aa)

YKLHNQIGKGSYADVYTA
||.  .||.|||| |. |
YKMLKTIGHGSYAKVKLA
Kinase GL50803_17378.AA MARK 122-140 36 0.001425 7.74 In-house 50-68 (262) Show / Hide 
Range on Protein: 122-140
Range on HMM: 50-68/262
Sequence Identity: 36% (7 aa)

ASLMDRLQHPNVVRLYEVF
...| .|.|||...|..|.
IEIMKKLDHPNIIKLFHVI
Kinase GL50803_17378.AA PLK 905-924 40 0.0019 7.21 In-house 180-199 (258) Show / Hide 
Range on Protein: 905-924
Range on HMM: 180-199/258
Sequence Identity: 40% (8 aa)

GMPSDVWQFGVALYSVLIGK
.. .|.| .|. .|  ||||
SYEVDCWSLGCIMYTLLIGK
Kinase GL50803_17378.AA ULK 950-975 34 0.001988 7.93 In-house 304-329 (329) Show / Hide 
Range on Protein: 950-975
Range on HMM: 304-329/329
Sequence Identity: 34% (9 aa)

DLLCGLLAPSPMQRYTMVEVVNHPFF
||. ..|   . .| .  |. |||.|
DLIRRMLQYDEKDRISWEELFNHPWF
Kinase GL50803_17378.AA Ciliate-E2a 123-140 50 0.003352 5.3 In-house 51-68 (275) Show / Hide 
Range on Protein: 123-140
Range on HMM: 51-68/275
Sequence Identity: 50% (9 aa)

SLMDRLQHPNVVRLYEVF
..| .| |||. .||||.
NIMRQLDHPNIIKLYEVY
Kinase GL50803_17378.AA Pkinase_Tyr 255-291 32 0.003801 11.28 Pfam 98-137 (270) Show / Hide 
Range on Protein: 255-291
Range on HMM: 98-137/270
Sequence Identity: 32% (13 aa)

LSSN---LKTLSLRDIVLIFYQIAYGLEYLHSLLIVHHDI
| ..    . |.. |.. . .||| |.|||.|  ..| |.
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase GL50803_17378.AA ULK 943-975 30 0.005252 6.58 In-house 292-324 (324) Show / Hide 
Range on Protein: 943-975
Range on HMM: 292-324/324
Sequence Identity: 30% (10 aa)

HLSLLLADLLCGLLAPSPMQRYTMVEVVNHPFF
..|  . ||. ..|   . .| .  |. |||.|
KISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase GL50803_17378.AA ULK 125-140 44 0.012306 5.25 In-house 67-84 (324) Show / Hide 
Range on Protein: 125-140
Range on HMM: 67-84/324
Sequence Identity: 44% (8 aa)

MDRLQHPN--VVRLYEVF
...|.|||  .|.||..|
LKELKHPNHHIVKLYDWF
Kinase GL50803_17378.AA Pkinase_Tyr 106-137 36 0.01708 9.07 Pfam 34-70 (270) Show / Hide 
Range on Protein: 106-137
Range on HMM: 34-70/270
Sequence Identity: 36% (14 aa)

KTL--GTQEAA---DKFLWSAASLMDRL-QHPNVVRLY
|.|  |. . .   ..|.   |..|  | .|||.||||
KMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLY
Kinase GL50803_17378.AA PLK 127-140 42 0.023169 3.62 In-house 55-68 (258) Show / Hide 
Range on Protein: 127-140
Range on HMM: 55-68/258
Sequence Identity: 42% (6 aa)

RLQHPNVVRLYEVF
.|.|||.|... .|
QLHHPNIVKFHHFF
Kinase GL50803_17378.AA PLK 68-107 20 0.027006 3.4 In-house 1-40 (258) Show / Hide 
Range on Protein: 68-107
Range on HMM: 1-40/258
Sequence Identity: 20% (8 aa)

YKLHNQIGKGSYADVYTAENTVLRKTFVLRMVDRIRLAKT
|.  . .|||  | .| ...   .. .   .|.. ...|.
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKP
Kinase GL50803_17378.AA AMPK 128-139 50 0.052306 1.82 In-house 56-67 (254) Show / Hide 
Range on Protein: 128-139
Range on HMM: 56-67/254
Sequence Identity: 50% (6 aa)

LQHPNVVRLYEV
. ||....||||
FRHPHIIQLYEV