Gene GL50803_17250 (G.lamblia)
GL50803_17250
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| GL50803_17250.AA | Protein | None | 854 | None | Fasta, JSON |
| GL50803_17250.kin_dom | Protein Kinase Domain | None | 272 | None | Fasta, JSON |
Protein domains of GL50803_17250.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| S_TKc | GL50803_17250.AA | S_TKc | 9-282 | 13 | 3.2e-07 | -71.09 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 9-282
Range on HMM: 1-231/231
Sequence Identity: 13% (43 aa)
YEAVRYLNSDIYGISYLVRDRNLDLSATCRIVSEADVGRGRYALIRDLARQAHRLDHESITPLLEAFVDDEQECIFLISRGAG--QSLYEYSEELCF--L
|| .| . . .| |..|... . . |.. ..| .. . .|. | |...|.| .. . | .|..| .. |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGL
QVNLEEEVIITILVELINAILYVYSTNRK------------------TDFTDALASNLPSTGLDPLCIRLSSKGRALVDYSAFAVKLAAQRHSAFTMAYL
.. . | .. .. ....|. | | . .|| | .. | |.
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDEHIKICDFGLARQL----------------------------------TTFCGTPWYM
CPEVLHSRHSGEDRARLNVSPLKMLAYNV--------GRLCCELCFAGSKCKAVKGEYDTAYMLKSIIKENAYSKDLVRVLTWLTNPCNNSRPYLDEVLA
|||| |. | . |.. . . |.| | |... . . . . || |.|.
APEVL--------------------GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQ
-------HPFI
||..
DEWDIKCHPWF
|
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| Kinase | GL50803_17250.AA | NEK | 246-282 | 28 | 0.000119 | 12.75 | In-house | 249-286 (286) | Show / Hide |
Range on Protein: 246-282 Range on HMM: 249-286/286 Sequence Identity: 28% (11 aa) IKENA-YSKDLVRVLTWLTNPCNNSRPYLDEVLAHPFI | .. ||.|| .... . .. .|| ...|..||| IPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI |
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| Kinase | GL50803_17250.AA | MLCK | 268-282 | 33 | 0.000244 | 6.78 | In-house | 243-257 (257) | Show / Hide |
Range on Protein: 268-282 Range on HMM: 243-257/257 Sequence Identity: 33% (5 aa) NSRPYLDEVLAHPFI ..|.. .| |.||.. EKRMTAHECLQHPWL |
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| Kinase | GL50803_17250.AA | Aur | 268-282 | 40 | 0.000497 | 5.97 | In-house | 243-257 (257) | Show / Hide |
Range on Protein: 268-282 Range on HMM: 243-257/257 Sequence Identity: 40% (6 aa) NSRPYLDEVLAHPFI ..| ||....||.| KQRMTLDQIMNHPWI |
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| Ank | GL50803_17250.AA | Ank | 333-354 | 45 | 0.001357 | 17.22 | Pfam | 1-22 (33) | Show / Hide |
Range on Protein: 333-354 Range on HMM: 1-22/33 Sequence Identity: 45% (10 aa) DGATALMAAAVLGNIEVLKILI || |.|. |. |..||.| |. DGFTPLHLACRCGHTEVVKMLL |
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| Ank | GL50803_17250.AA | Ank | 369-389 | 52 | 0.003317 | 15.82 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 369-389 Range on HMM: 1-21/33 Sequence Identity: 52% (11 aa) NGATALILAARNGQTEACKLL .| |.| ||.|.|.|| .|.| DGFTPLHLACRCGHTEVVKML |
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| Ank | GL50803_17250.AA | Ank | 400-433 | 35 | 0.006362 | 14.8 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 400-433 Range on HMM: 1-33/33 Sequence Identity: 35% (12 aa) DGFTALMEATVRGHSSAADVLMKYEAKSVIQLDD ||||.|. | .|| . . |.. .| || DGFTPLHLACRCGHTEVVKMLLQ-HGADVNAQDD |
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| Ank | GL50803_17250.AA | Ank | 439-464 | 34 | 0.010335 | 14.04 | Pfam | 1-26 (33) | Show / Hide |
Range on Protein: 439-464 Range on HMM: 1-26/33 Sequence Identity: 34% (9 aa) NGTTALMLACEFHQLHIANSLIQYEA .| |.|.|||. .. .. |.|. | DGFTPLHLACRCGHTEVVKMLLQHGA |
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| Ank | GL50803_17250.AA | Ank | 470-491 | 40 | 0.006201 | 14.84 | Pfam | 1-22 (33) | Show / Hide |
Range on Protein: 470-491 Range on HMM: 1-22/33 Sequence Identity: 40% (9 aa) SGYTALHRAAALGLVSAVKLLI |.|.|| |. | .. ||.|. DGFTPLHLACRCGHTEVVKMLL |
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| Ank | GL50803_17250.AA | Ank | 502-522 | 38 | 0.000256 | 19.83 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 502-522 Range on HMM: 1-21/33 Sequence Identity: 38% (8 aa) KGQTALMFAAQYGHSKCVELL |.|.|. |...|| ..|..| DGFTPLHLACRCGHTEVVKML |
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| Ank | GL50803_17250.AA | Ank | 534-557 | 37 | 0.001719 | 16.85 | Pfam | 1-24 (33) | Show / Hide |
Range on Protein: 534-557 Range on HMM: 1-24/33 Sequence Identity: 37% (9 aa) KGWSALMSAITNGHTEAAKLLIDY |...|. |. .|||| .|.|... DGFTPLHLACRCGHTEVVKMLLQH |
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| Ank | GL50803_17250.AA | Ank | 565-585 | 38 | 0.00069 | 18.28 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 565-585 Range on HMM: 1-21/33 Sequence Identity: 38% (8 aa) MGYTPLMCAVEHKQYEVIDLL .|.|||..|... ..||. .| DGFTPLHLACRCGHTEVVKML |
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| Ank | GL50803_17250.AA | Ank | 605-627 | 26 | 0.022092 | 12.85 | Pfam | 1-23 (33) | Show / Hide |
Range on Protein: 605-627 Range on HMM: 1-23/33 Sequence Identity: 26% (6 aa) NGATALMLAAYSNDADGCRKLVE .| |.|.||....... .. |.. DGFTPLHLACRCGHTEVVKMLLQ |
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| Ank | GL50803_17250.AA | Ank | 636-656 | 23 | 2.261281 | 5.6 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 636-656 Range on HMM: 1-21/33 Sequence Identity: 23% (5 aa) DGMTASMIAASNDSAAALSIL ||.|. ..|...... .. | DGFTPLHLACRCGHTEVVKML |
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| Ank | GL50803_17250.AA | Ank | 673-705 | 24 | 0.004148 | 15.47 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 673-705 Range on HMM: 1-33/33 Sequence Identity: 24% (8 aa) DNRTCLMIAALSRSLSCVRVLAEQRIGMGCQDG | .|.|..|... ....|. | .. || DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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| Ank | GL50803_17250.AA | Ank | 706-726 | 33 | 0.021535 | 12.89 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 706-726 Range on HMM: 1-21/33 Sequence Identity: 33% (7 aa) KGSTALIMAALSGYADICKVL | |.| .|...|.....| | DGFTPLHLACRCGHTEVVKML |
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| Ank | GL50803_17250.AA | Ank | 737-765 | 48 | 2e-06 | 27.46 | Pfam | 1-29 (33) | Show / Hide |
Range on Protein: 737-765 Range on HMM: 1-29/33 Sequence Identity: 48% (14 aa) DGFTALMSAAQEGHKECVSILLSKEGDVH ||||.|. |.. ||.|.|. ||.. ||. DGFTPLHLACRCGHTEVVKMLLQHGADVN |
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| Ank | GL50803_17250.AA | Ank | 768-788 | 33 | 0.006568 | 14.75 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 768-788 Range on HMM: 1-21/33 Sequence Identity: 33% (7 aa) GGWTALMSAALKNKPEIVQIL |.|.|. |.... .|.|. | DGFTPLHLACRCGHTEVVKML |
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| Ank | GL50803_17250.AA | Ank | 802-822 | 42 | 3.5e-05 | 22.93 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 802-822 Range on HMM: 1-21/33 Sequence Identity: 42% (9 aa) DGITALMIAVQSGHIECIRIL || |.|..|...||.|... | DGFTPLHLACRCGHTEVVKML |
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