Gene GL50803_16826 (G.lamblia)

GL50803_16826

Species: G.lamblia
Alias: GL50803_16826, GK291
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_16826.AA Protein None 497 None Fasta, JSON
GL50803_16826.kin_dom Protein Kinase Domain None 267 None Fasta, JSON

Protein domain

Protein domains of GL50803_16826.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc GL50803_16826.AA S_TKc 21-276 17 7.1e-10 -32.12 SMART 1-231 (231) Show / Hide 
Range on Protein: 21-276
Range on HMM: 1-231/231
Sequence Identity: 17% (52 aa)

FE-----------KVYAATDDQ-RRDLLIREVDFSSMPKSGAQRILAAYSLLSKLSSPGLVGCTIVKTTPSSLVAELDITGA--TTLASYIRHRTVLGDR
.|           ||| ...    |   | ...         ..|.   ..|.|   | .| .  |  . ..|   ..  .    .| .||..|   | |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LPEEQILRITYQIAAVLSFLSSG------------LISIGNAPVRLACLSLSPQTIYIHGGSTIMLGDFSSSSIHGSRISGPLPPERCYLSPEVWADR
  .|| .. ...|||.  | .. |             |..                        .|...|| .. .  . . |     . |..|||    
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----------------------HIKICDFGLARQL-TTFCGT----PWYMAPEVL--G

ISSPCVDMWSLGCIVYELCTGVPPPLLSVESAGLNAAIKQYTASILADISKTPYSKGISALVEGLLA-PASARLSASAVME-------HEAM
 . . .|.||.|||.||...| ||         ... .|.              |.    .....|    . |..|  ...       |. .
YGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_16826.AA AGC 183-216 41 2.2e-09 18.9 In-house 273-304 (395) Show / Hide 
Range on Protein: 183-216
Range on HMM: 273-304/395
Sequence Identity: 41% (15 aa)

YLSPEVWADRISSPCVDMWS--LGCIVYELCTGVPP
|..||.      .. .| ||  |||. ||. || ||
YMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPP
Kinase GL50803_16826.AA ULK 183-217 35 1.1e-08 26.58 In-house 217-256 (329) Show / Hide 
Range on Protein: 183-217
Range on HMM: 217-256/329
Sequence Identity: 35% (14 aa)

YLSPEVWADR--ISSPC---VDMWSLGCIVYELCTGVPPP
| .|... ..     ..   .|.|||||| ||. .| ||.
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPF
Kinase GL50803_16826.AA MAST 183-216 42 2.5e-08 20.84 In-house 234-268 (337) Show / Hide 
Range on Protein: 183-216
Range on HMM: 234-268/337
Sequence Identity: 42% (15 aa)

YLSPEVWADRI-SSPCVDMWSLGCIVYELCTGVPP
|..|||   .  ... || ||.| |.||. .|.||
YIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPP
Kinase GL50803_16826.AA ULK 183-217 32 3.4e-08 25.26 In-house 213-252 (324) Show / Hide 
Range on Protein: 183-217
Range on HMM: 213-252/324
Sequence Identity: 32% (13 aa)

YLSPEVWADR--ISSPC---VDMWSLGCIVYELCTGVPPP
| .|... ..     ..   .|.|||||| ||. .| .|.
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPF
Kinase GL50803_16826.AA Akt 183-216 42 5.7e-08 21.48 In-house 168-202 (264) Show / Hide 
Range on Protein: 183-216
Range on HMM: 168-202/264
Sequence Identity: 42% (15 aa)

YLSPEVWADRISSPCVDMWS-LGCIVYELCTGVPP
||.||.  .   . .|| |. |||. ||...| ||
YLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPP
Kinase GL50803_16826.AA Fused 183-216 50 6.3e-08 23.08 In-house 163-196 (251) Show / Hide 
Range on Protein: 183-216
Range on HMM: 163-196/251
Sequence Identity: 50% (17 aa)

YLSPEVWADRISSPCVDMWSLGCIVYELCTGVPP
|..||  . .      ||||||||.|||  | ||
YMAPELVEEQPYDHHADMWSLGCILYELMVGQPP
Kinase GL50803_16826.AA CDK 194-215 42 6.3e-08 21.27 In-house 198-223 (284) Show / Hide 
Range on Protein: 194-215
Range on HMM: 198-223/284
Sequence Identity: 42% (11 aa)

S-SPCVDMWSLGCIVYELCT---GVP
| .. .||||.||| .|. |   . |
SGGTPIDMWSVGCIFAEMFTDVTRKP
Kinase GL50803_16826.AA NEK2 183-216 41 1.1e-07 21.85 In-house 230-263 (319) Show / Hide 
Range on Protein: 183-216
Range on HMM: 230-263/319
Sequence Identity: 41% (14 aa)

YLSPEVWADRISSPCVDMWSLGCIVYELCTGVPP
| |||.  ..  ..  | ||.||..||.|.  ||
YMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPP
Kinase GL50803_16826.AA DYRK1 156-215 45 1.7e-07 21.89 In-house 143-201 (321) Show / Hide 
Range on Protein: 156-215
Range on HMM: 143-201/321
Sequence Identity: 45% (27 aa)

STIMLGDFSSSSIHGSRISGPLPPERCYLSPEVWADRISSPCVDMWSLGCIVYELCTGVP
| | . || ||   | ||   .   | | ||||  .   .  .||||||||. |. || |
SAIKIIDFGSSCQLGQRIYQYI-QSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGEP
Kinase GL50803_16826.AA Pkinase 183-216 51 2.1e-07 27.26 Pfam 177-211 (293) Show / Hide 
Range on Protein: 183-216
Range on HMM: 177-211/293
Sequence Identity: 51% (18 aa)

YLSPEVWA-DRISSPCVDMWSLGCIVYELCTGVPP
|..|||   ..  .| |||||.|||.||...| ||
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPP
Kinase GL50803_16826.AA NEK 182-212 48 2.8e-07 22.1 In-house 189-219 (286) Show / Hide 
Range on Protein: 182-212
Range on HMM: 189-219/286
Sequence Identity: 48% (15 aa)

CYLSPEVWADRISSPCVDMWSLGCIVYELCT
.|.||||. ..  .  .|.|||||..||.||
YYMSPEVCQNKPYNNKSDIWSLGCVLYEMCT
Kinase GL50803_16826.AA NEK 92-120 25 0.202329 1.24 In-house 93-124 (286) Show / Hide 
Range on Protein: 92-120
Range on HMM: 93-124/286
Sequence Identity: 25% (8 aa)

TLASY---IRHRTVLGDRLPEEQILRITYQIA
.|.     | ...  |. ..||||... .|..
DLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMC
Ank GL50803_16826.AA Ank 410-433 45 6.4e-05 22.01 Pfam 1-24 (33) Show / Hide 
Range on Protein: 410-433
Range on HMM: 1-24/33
Sequence Identity: 45% (11 aa)

TGTTALMIAAFKGHLPVVTLLLNH
 | |.|..|...||. ||..||.|
DGFTPLHLACRCGHTEVVKMLLQH
Ank GL50803_16826.AA Ank 441-471 36 0.001281 17.31 Pfam 1-33 (33) Show / Hide 
Range on Protein: 441-471
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

RGRNALQYAVRAGQPECVKALLE--AEFDELDV
 |. .| .|.| |..|.|| ||.  |. .  | 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD