Gene GL50803_16034 (G.lamblia)

GL50803_16034

Species: G.lamblia
Alias: GL50803_16034, GK013
External Links: GiardiaDB ,
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: AMPK

Sequence

Name Sequence Type Origin Length Description Download
GL50803_16034.AA Protein None 432 None Fasta, JSON
GL50803_16034.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of GL50803_16034.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_16034.AA AMPK 21-274 55 2.5e-168 503.79 In-house 1-254 (254) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-254/254
Sequence Identity: 55% (142 aa)

YITGKSLGVGTFGDVRLATHLITGERVALKVLDKSRIQCEDDFKRIVREIQVLKLLDHSNIVRLLEVI-DTPRHIYLVTEYVDNGELFNYVVQKQKLSEE
||.|| .|.|||| | ..|| .||| ||.|.|.| .|. .|. .|| |||. |||. | .|..| ||| .||. |..|.||| .|||| |.|....|.|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EACKYFHQIVSALSYCHSRKVCHRDMKLENVLLDSSYNIKLIDFGLSNILMSDEAKFKTACGSPSYASPEMLSGKKYHGPSIDVWAIGIILFAMICGHLP
|||..| ||.|...|||  .. |||.|.||.|||  .|||. ||||||. |.|  . ||||||| ||.||| |||.| || .|.|  |.||.||.|| ||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNM-MKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

FDHDNTETLYKKIISGVFHIPDHVSPEAADLISKILVVDPDKRITLDEITKHPWY
|| .|| ||||||..|.. ||...||||.|||...| ||| |||| ..| .|||.
FDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase GL50803_16034.AA CAMKL 21-274 46 4.90000000001e-151 485.35 In-house 1-297 (297) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-297/297
Sequence Identity: 46% (139 aa)

YITGKSLGVGTFGDVRLATH-LITGERVALKVLDKSRIQC-------------EDDFKRIVREIQVLKLLD---HSNIVRLLEVIDTPRH------IYLV
|. || || |.|| |.|||| ..|||.|| |..||..|..             |.|  || |||| .|.|.   | ||..|.|||.||.|      ||||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

TEYVDNGE--LFNYVVQK----QKLSEEEACKYFHQIVSALSYCHSRKVCHRDMKLENVLLDSSY--NIKLIDFGLSNILMS----DEAKFKTACGSPSY
.||...||  ||.|.|..    ....|.||..|| |||||..||||....||| |.||.|||..   |||.||||.||. .     .. |.|| ||||.|
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

ASPEMLSG--KKYHGPSIDVWAIGIILFAMICGHLPFDHD--------NTETLYKKIISGVFHIP--DHVSPEAADLISKILVVDPDKRITLDEITKHPW
..||...|  |.|.|| .|.|..|.||.||.||.|||| |        |. .||.||..| ...|   ||| .. |||.|.|.|.|.||.|...| .|||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

Y
.
M
Kinase GL50803_16034.AA MARK 21-274 44 4.90000000001e-136 447.05 In-house 1-262 (262) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-262/262
Sequence Identity: 44% (117 aa)

YITGKSLGVGTFGDVRLATHLITGERVALKVLDKSRIQCEDDFKRIVREIQVLKLLDHSNIVRLLEVID--TPRH-IYLVTEYVDNGELFNYVVQK--QK
|  .| .| |... |.||.|. ||..||.|...| ...    .| . |||...|.||| ||..|..||.  |..| |||. ||. .|||..|....   .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSEEEACKYFHQIVSALSYCHSRKVCHRDMKLENVLLDSSY--NIKLIDFGLSNILMSDEAKFKTACGSPSYASPEMLSGKKYHGPSIDVWAIGIILFAM
|.|||| ..|.|||||..||||. ..|||.|.||.|.|.    |||.||||.|.. .... | .| ||.|.|..||....|.| || .|.|. |..|..|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQ-KLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

ICGHLPFDHDN--TETLYKKIISGVFHIPDHVSPEAADLISKILVVDPDKRITLDEITKHPWY
.||..||| |.   ..||||| .|...||.|||.|. .||...|.|.|..|.|..|| |||| 
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase GL50803_16034.AA CAMK 26-274 27 4.5e-132 428.17 In-house 1-425 (425) Show / Hide 
Range on Protein: 26-274
Range on HMM: 1-425/425
Sequence Identity: 27% (119 aa)

SLGVGTFGDVRLATHLITG------------ERVALKVLDKSRIQC-------------------------EDDFKRIVREIQVLKL-------LDHSNI
 || |.|| |.|..|  |.            ..|| |..||....                          . | |.. |||...|.       ||| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLLEVID------------TPRH--------IYLVT---EYVDNGEL----FNYVVQK---------------QKLSEEEACKYFHQIVSALSYCHSRK
..|.||..            | ..        .|.|.   ||...|||    |.|.|..                ...|.||..||.||.||. ||||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VCHRDMKLENVLLDSS-----------------YNIKLIDFGLSNILMSDE-----------------------AKFKTACGSPSYAS-PEMLSG-----
..||| |.||.|||..                 .|||.||||..|.....|                        |.|| ||.|.|.. ||.|.|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KKYHGPSIDVWAIGIILFAMICGHLPFDHD-------------NTETLYKKIISGVFH-IPDH-----------------------VSPEAA
        |.|.||..|.|..|.||..| ||..||..|             | . |..||..| .. .|..                       ||.|. 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLISKILVVDPDKRITLDEITKHPWY
|||.|.|.|||.||.|.... .|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_16034.AA NuaK 21-274 43 1.6e-117 310.61 In-house 1-252 (252) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-252/252
Sequence Identity: 43% (111 aa)

YITGKSLGVGTFGDVRLATHLITGERVALKVLDKSRIQCEDDFKRIVREIQVLKLLDHSNIVRLLEVIDTPRHIYLVTEYVDNGELFNYVVQKQKLSEEE
|   | || ||.| |.|||   ||  || |   |..|. | |  .| |||...  |.| .|.   ||      | .| ||   |||..|. ....|.|.|
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ACKYFHQIVSALSYCHSRKVCHRDMKLENVLLDSSYNIKLIDFGLSNILMSDEAKFKTACGSPSYASPEMLSGKKYHGPSIDVWAIGIILFAMICGHLPF
| . | |||||. |||  ..||||.||||.|||   |.|  |||||| . .|.   .| |||| |||||   |. |||| .| |. |..|..|. | .||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSN-YYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPF

DHDNTETLYKKIISGVFHIPDHVSPEAADLISKILVVDPDKRITLDEITKHPWY
| ..  .| | | .| .  | . | .|  || ..| |.|..| |. .| .|.| 
DGHDFKHLVKQISQGAYYEPCKPS-DACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase GL50803_16034.AA QIK 21-274 40 8.70000000001e-114 384.33 In-house 1-272 (272) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-272/272
Sequence Identity: 40% (110 aa)

YITGKSLGVGTFGDVRLATHLITGERVALKVLDKSRIQCEDDFKRIVREIQVLKLLDHSNIVRLLEVIDTPRHIYLVTEYVDNGELFNYVVQKQK-----
|  .. .| | |. |.||.| || ..|| |..|||..  |.......||.|..|.|.| .|..|..|. | . .|.||||  |||.| |.... .     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLD-EENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LSEEEACKYFHQIVSALSYCHSRKVCHRDMKLENVLLDSSYNIKLIDFGLSNILMSDEAKFKTACGSPSYASPEMLSGKKYHGPS
               ..|.|| . | ||.||  |||.|.. |||.| ||.|||.  |||..|||.||   ...   .| |||| || |||. ||.| || 
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQL-LMTWCGSPPYAAPEMFEGKEYDGPK

IDVWAIGIILFAMICGHLPFDHDNTETLYKKIISGVFHIPDHVSPEAADLISKILVVDPDKRITLDEITKHPWY
.|.| .|..|....|| |||| .. ..| ....|| | ||  .| . ..|| . |||||..|.| . | .|.| 
VDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase GL50803_16034.AA S_TKc 21-274 37 6.30000000001e-109 369.1 SMART 1-231 (231) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-231/231
Sequence Identity: 37% (101 aa)

YITGKSLGVGTFGDVRLATHLITGERVALKVLDKSRIQCEDDFKRIVREIQVLKLLDHSNIVRLLEVIDTPRHIYLVTEYVDN--GELFNYVVQKQK---
|  .. .| |.|| |....|  ||..||.|...          ..| ||||.||  .| |||.|..|...  |.|.|.||.|.  |.|| | .....   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LSEEEACKYFHQIVSALSYCHSRKVCHRDMKLENVLLDSSYNIKLIDFGLSNILMSDEAKFKTACGSPSYASPEMLSGKKYHGP-SIDVWAIGIILF
   ..| .|..|..||..|| ||||....||| | ||.|||.  .||..||||. .|       .| ||.| | .||.|     .|. ..|.|..|.||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILY

AMICGHLPFDHDNTETLYKKIISGVFHIPDHVSPEAADLISKILVVDPDKRITLDEITK-------HPWY
 |.||  ||.  . ....|||           |||| |.|.|.|..||.||.|  |. .       ||| 
EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_16034.AA Pkinase 21-274 32 1.3e-100 345.34 Pfam 1-293 (293) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-293/293
Sequence Identity: 32% (97 aa)

YITGKSLGVGTFGDVRLATHLITGERVALKVLDKSRIQCEDDFKRIV-REIQVLKLLDHSNIVRLLEVIDTPRHIYLVTEYVDNG----ELFNYVV--QK
| .|. .| |.|| |....|  ||..||.|...|... .. |  ..  .|||..| |.| |||||...  ...|||.|.||...|    .|| |.   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

QKL--SEEEACKYFHQIVSALSYCHSRKVCHRDMKLENVLLDSSYNI----KLIDFGLSNIL-MSDEAKFKTACGSPSYASPEMLSGKKYHGPSIDVWAI
 ..  ||.|...|. ||...| ||||....|||.|.||.|.|. ..|    |..||||.  .       ..| ||.| |..|| . | .|.||..|.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIILFAMICGHLPFDHD------NTETLYKKIISGVFHIPDHVS---------------------PEAADLISKILVVDPDKRITLDEITKHPWY
|.||. |.||..||...      .   ....| .. .| .   .                     .|. |.|...| .|| ||.| ..| .||| 
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase GL50803_16034.AA BRSK 21-274 45 1.2e-99 337.32 In-house 1-254 (254) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-254/254
Sequence Identity: 45% (117 aa)

YITGKSLGVGTFGDVRLATHLITGERVALKVLDKSRIQ-CEDDFKRIVREIQVLKLLDHSNIVRLLEVIDTPRHIYLVTEYVDNGELFNYVVQKQKLSEE
|. .| || |. | |.| .| .||..|| |.  | .    |   ... ||| ..|| || .. .. .|  . .  ||. |.|  |||| | |.| .|   
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

EACKYFHQIVSALSYCHSRKVCHRDMKLENVLLDSSYNIKLIDFGLSNILMSDEAKFKTACGSPSYASPEMLSGKKYHGPSIDVWAIGIILFAMICGHLP
|| |.| ||.||| .|||. .||||.| || |||   |||  |||.  . . |     | |||| ||.||  .| || |   |||  |.||.|.  | ||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMM-LHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALP

FDHDNTETLYKKIISGVFHIPDHVSPEAADLISKILVVDPDKRITLDEITKHPWY
|| ||   |  |.  ||||.|  . | . ||  . . |||||||.| || |||||
FDDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase GL50803_16034.AA MELK 21-274 42 9.3e-93 314.47 In-house 1-254 (254) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-254/254
Sequence Identity: 42% (109 aa)

YITGKSLGVGTFGDVRLATHLITGERVALKVLDKSRIQCEDDFKRIVREIQVLKLLDHSNIVRLLEVIDTPRHIYLVTEYVDNGELFNYVVQKQKLSEEE
|   . .| | |. |.||.|..|...||.|..|| ..   .|. |.  |.. || | | .| .|  .|.|   |..| ||   ||.|.|......|.|||
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQL--GHDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEE

ACKYFHQIVSALSYCHSRKVCHRDMKLENVLLDSSYNIKLIDFGLSNILMSDEAKF--KTACGSPSYASPEMLSGKKYHGPSIDVWAIGIILFAMICGHL
. ..| |||||..| ||.   |||.| ||.|.|  ...|||||||         .   .| |||| || ||...||.| |   |||..||.|....|| |
TRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PFDHDNTETLYKKIISGVFHIPDHVSPEAADLISKILVVDPDKRITLDEITKHPWY
||| || . .||||.||... |...|||. .|. ..| |||.||| . .. .||| 
PFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase GL50803_16034.AA GIN4 66-274 50 4.4e-92 294.41 In-house 81-293 (293) Show / Hide 
Range on Protein: 66-274
Range on HMM: 81-293/293
Sequence Identity: 50% (107 aa)

IVREIQVLKLLDHSNIVRLLEVIDTPRHIYLVTEYVDNGELFNYVVQKQKLSEEEACKYFHQIVSALSYCHSRKVCHRDMKLENVLLDSSYN-IKLIDFG
| ||| ..||..|.|..|| .| .|   .||| ||.. ||||||.|.. .| | || .||.||.  .||||.  .||||.| ||.|||. || ||. |||
IEREIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFG

LSNILMSDEAKFKTACGSPSYASPEMLSGKKYHGPSIDVWAIGIILFAMICGHLPFDHD--NTETLYKKIISGVFHIPDH--VSPEAADLISKILVVDPD
.   |  |.   .|.|||| ||.||. .|  ||| . |||. |.||||.. |||||| .  |  .|  |. .| ...|.   .| || |||.|||||||.
MA-ALETDNKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPE

KRITLDEITKHPWY
|||.  .| |||  
KRIKTRDILKHPLI
Kinase GL50803_16034.AA Ciliate-E2 21-274 25 4.3e-91 308.94 In-house 1-365 (365) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)

YITGKSLGVGTFGDVRLATHLITGER-----------------------VALKVLDKSRIQCEDDFKRIVREIQ----------VLKLLDHSNIVRLLEV
|.  | .| |.||.|.....  ....                       .|.|.. |. |.     ..| |||.          .|..|.| ||... |.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

ID--TPRHIYLVTEYVDNGELFNYVVQK-----------QKLSEEEACKYFHQIVS---------------ALSYCHSRK-VCHRDMKLENVLLDSSYNI
    .  .||||.||.. |.|| |  ..           ....|.|..... ||..               || |.||.. ..||| |.||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLIDFGLSNILMSD-------------------------------EAKFKTACGSPSYASPEMLSGKKY--------HGPSIDVWAIGIILFAMICGHLP
|.|||||| ..  |                               .  |.| ||.| | .||.|.||||        .. ..|.|..|.||. |..| .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FDHDNTETLYKKIISGVFHIP------------------DHVSPEAADLISK----ILVVDPDKRIT-LDEITKHPWY
|        ...|. . . .|                  ...|.|. |||.|    .|..||.||||  ..| .||| 
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_16034.AA Pkinase_Tyr 21-173 30 8.4e-21 71.07 Pfam 1-165 (270) Show / Hide 
Range on Protein: 21-173
Range on HMM: 1-165/270
Sequence Identity: 30% (52 aa)

YITGKSLGVGTFGDVRLATHL----ITGERVALKVLDKSRIQCEDD---FKRIVREIQVLKLL-DHSNIVRLLEVID-TPRH--IYLVTEYVDNGELFNY
 . || || | ||.|...|       |.  || |.| |   .. ..    .   ||....| | .| |||||. |.    ..  ||.|.||. .| | .|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

VVQ----KQKLSEEEACKYFHQIVSALSYCHSRKVCHRDMKLENVLLDSSYNIKLIDFGLSNILMSDE
  .    ||.|. .. ... .|| ....| .|..  |||    |.|....  .|  ||||.  ...|.
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDD
Kinase GL50803_16034.AA TyrKc 21-278 22 5.7e-17 51.67 SMART 1-280 (280) Show / Hide 
Range on Protein: 21-278
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

YITGKSLGVGTFGDVRLATHLITGERVALKVLDKSRIQCEDDFKRIVREIQVLKLL--DHSNIVRLLEVIDTP-------RHIYLVTEYVDNGELFNYVV
   || || | || |...|     . || |.| ..        . . ||..... |  .| |||||. |. ..         ...|.||...| | .|  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QKQK-LSEEEACKYFHQIVSALSYCHSRKVCHRDMKLENVLLDSSYNIKLIDFGLSNILMSD-------EAKFKTA-CGSPS-----YASPEMLSGKKYH
 ... |. .. ... .|| .  .| ||... |||    |.|... . .|  |||||  . .|       . . |.   |. .       .|| .  .|. 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-

GPSIDVWAIGIILF-AMICGHLPFDH-----DNTETLYKKIISG-VFHIPDH--------VSPEAADLISKILVVDPDKRITLDEITKHPWYIQCY
 .  |||. |. ..  .  |  |         . . ..... .|    .|..         ..|  .....    ||..| |  ||      ..| 
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------HECF
Kinase GL50803_16034.AA GIN4 21-57 43 3.2e-07 18.67 In-house 1-37 (293) Show / Hide 
Range on Protein: 21-57
Range on HMM: 1-37/293
Sequence Identity: 43% (16 aa)

YITGKSLGVGTFGDVRLATHLITGERVALKVLDKSRI
.  |. ||.|  | |.|| .  ||.| |.||. | .|
WKLGETLGFGSTGKVQLAKNMETGQRAAVKVISKKKI
UBA_CAMKL GL50803_16034.AA UBA_CAMKL 295-334 41 1.4e-14 50.41 In-house 1-41 (41) Show / Hide 
Range on Protein: 295-334
Range on HMM: 1-41/41
Sequence Identity: 41% (17 aa)

DFRIIYTMVTKISDWSATKIIRSLNNNRH-NQMTATYFLLC
| .||  |... .... ..||.||.||.. |..||||.||.
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL