Gene GL50803_11775 (G.lamblia)
GL50803_11775
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| GL50803_11775.AA | Protein | None | 1618 | None | Fasta, JSON |
| GL50803_11775.kin_dom | Protein Kinase Domain | None | 283 | None | Fasta, JSON |
Protein domains of GL50803_11775.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| S_TKc | GL50803_11775.AA | S_TKc | 6-288 | 12 | 1.4e-08 | -51.15 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 6-288 Range on HMM: 1-231/231 Sequence Identity: 12% (40 aa) YTLISQVSATENCKTMLVQHNG-TGNYAFKYFYTSWPVPNARLRSCMDAYLQLTCPHIIRLQTYSIDTAFTLVTDMTNG--PSLRSLIIKRRI--AQQWF |... .. | ....|.. .| | ..|. .. . .|.|..| . |. . .|... .| .|...| ||. ...| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF TSVEIWLLITQLLEGVKAYQSF------------------------YARVGAAADTPPNLFLSPFFILISDEERMKLQITEFYQTLLLPSVQRLYATSGV . ... .. |...... | ||. . | PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL----------------------------------------TTFCGTPWY APPEVSKHLPISA-SADIWMIGAILYELLT----LQQLDLDRLIELNSDVVTLAKIDNLYPIDYEPLEPYQSVAVYSFLDHGKAFRYRELYSLLSCMLII .||| . . ..|.| .| ||||.|. . ........ .|. .... .| MAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------------------------------SPEAKDFIRKCLQK NPDKRPPVELLLD-------YALL .|.||| . .| . DPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | GL50803_11775.AA | RSKL | 179-205 | 44 | 4e-06 | 8.99 | In-house | 347-373 (436) | Show / Hide |
Range on Protein: 179-205 Range on HMM: 347-373/436 Sequence Identity: 44% (12 aa) PEVSKHLPISASADIWMIGAILYELLT |||. . |.| ||.|||||. PEVGQIWELTEACDWWSYGAVLYELLC |
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| Kinase | GL50803_11775.AA | Ciliate-D1 | 192-210 | 52 | 2.8e-05 | 18.47 | In-house | 1-19 (19) | Show / Hide |
Range on Protein: 192-210 Range on HMM: 1-19/19 Sequence Identity: 52% (10 aa) DIWMIGAILYELLTLQQLD ||| .| ||||.|. |. . DIWSFGCILYEMLFGQPPF |
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| Kinase | GL50803_11775.AA | DRAK | 179-205 | 40 | 0.000146 | 9.47 | In-house | 170-196 (259) | Show / Hide |
Range on Protein: 179-205 Range on HMM: 170-196/259 Sequence Identity: 40% (11 aa) PEVSKHLPISASADIWMIGAILYELLT ||. . ||. . |.| || . | .|| PEILNYDPITMATDMWSIGVLTYVMLT |
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| Kinase | GL50803_11775.AA | NEK10 | 179-207 | 41 | 0.000164 | 10.53 | In-house | 189-217 (279) | Show / Hide |
Range on Protein: 179-207 Range on HMM: 189-217/279 Sequence Identity: 41% (12 aa) PEVSKHLPISASADIWMIGAILYELLTLQ ||. . .| ||.| .| .||.. ||| PEIVQSEPYGEKADVWAFGCCLYQMCTLQ |
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| Kinase | GL50803_11775.AA | MLK | 179-205 | 36 | 0.000202 | 11.4 | In-house | 202-231 (291) | Show / Hide |
Range on Protein: 179-205 Range on HMM: 202-231/291 Sequence Identity: 36% (11 aa) PEV---SKHLPISASADIWMIGAILYELLT ||| ... . | ..|.| .| .|.|.|| PEVIQQFRCEKYSEKCDVWSWGVVLWEMLT |
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| Kinase | GL50803_11775.AA | NEK2 | 259-288 | 23 | 0.00047 | 9.41 | In-house | 290-319 (319) | Show / Hide |
Range on Protein: 259-288 Range on HMM: 290-319/319 Sequence Identity: 23% (7 aa) RELYSLLSCMLIINPDKRPPVELLLDYALL |.| . . |. ... .|| .| .| . .. RHLNEIIHFMINVDHYHRPSIEEILQHPQI |
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| Kinase | GL50803_11775.AA | NEK | 179-207 | 44 | 0.00054 | 10.41 | In-house | 193-221 (286) | Show / Hide |
Range on Protein: 179-207 Range on HMM: 193-221/286 Sequence Identity: 44% (13 aa) PEVSKHLPISASADIWMIGAILYELLTLQ ||| .. | . .|||..| .|||. ||. PEVCQNKPYNNKSDIWSLGCVLYEMCTLK |
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| Kinase | GL50803_11775.AA | MSK | 177-205 | 29 | 0.000723 | 8.95 | In-house | 172-205 (277) | Show / Hide |
Range on Protein: 177-205 Range on HMM: 172-205/277 Sequence Identity: 29% (10 aa) APPEVSK----HLP-ISASADIWMIGAILYELLT ..||. . . . ... |.| |.|||..|| MAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLT |
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| Kinase | GL50803_11775.AA | NEK8 | 260-288 | 24 | 0.000788 | 6.68 | In-house | 250-278 (278) | Show / Hide |
Range on Protein: 260-288 Range on HMM: 250-278/278 Sequence Identity: 24% (7 aa) ELYSLLSCMLIINPDKRPPVELLLDYALL |. .| . | |..||.. .... |. EMRMLVHNCLQQDPEQRPSASQIMAMPLC |
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| Kinase | GL50803_11775.AA | NEK8 | 192-206 | 46 | 0.001099 | 6.26 | In-house | 204-218 (278) | Show / Hide |
Range on Protein: 192-206 Range on HMM: 204-218/278 Sequence Identity: 46% (7 aa) DIWMIGAILYELLTL |.| .| .|||...| DMWALGCVLYEMCCL |
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| Kinase | GL50803_11775.AA | NEK1 | 259-288 | 40 | 0.002297 | 7.73 | In-house | 247-276 (276) | Show / Hide |
Range on Protein: 259-288 Range on HMM: 247-276/276 Sequence Identity: 40% (12 aa) RELYSLLSCMLIINPDKRPPVELLLDYALL .|| ||.| |. .|| || | .| . YELQSLVSQMFKRNPRHRPSVNQILERPFI |
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| Kinase | GL50803_11775.AA | NEK1 | 192-206 | 66 | 0.002688 | 7.49 | In-house | 203-217 (276) | Show / Hide |
Range on Protein: 192-206 Range on HMM: 203-217/276 Sequence Identity: 66% (10 aa) DIWMIGAILYELLTL ||| | .||||.|| DIWSLGCVLYELCTL |
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| Kinase | GL50803_11775.AA | NEK | 259-288 | 30 | 0.004325 | 7.19 | In-house | 257-286 (286) | Show / Hide |
Range on Protein: 259-288 Range on HMM: 257-286/286 Sequence Identity: 30% (9 aa) RELYSLLSCMLIINPDKRPPVELLLDYALL ..| .|.| || .|..|| .. .| .. QDLQNLISQMLQKDPEQRPSCNQILEMPFI |
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| Kinase | GL50803_11775.AA | NEK2 | 179-206 | 32 | 0.109212 | 1.32 | In-house | 233-260 (319) | Show / Hide |
Range on Protein: 179-206 Range on HMM: 233-260/319 Sequence Identity: 32% (9 aa) PEVSKHLPISASADIWMIGAILYELLTL ||. . .. . ||| .| ..||. .| PEQMHGQKYNEKSDIWSVGCLIYEMCAL |
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| Ank | GL50803_11775.AA | Ank | 374-394 | 38 | 0.009695 | 14.14 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 374-394 Range on HMM: 1-21/33 Sequence Identity: 38% (8 aa) DGNTALVYAIKANNEDAVKIL ||.|.| .|.. .... || | DGFTPLHLACRCGHTEVVKML |
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| Ank | GL50803_11775.AA | Ank | 405-425 | 42 | 0.005564 | 15.01 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 405-425 Range on HMM: 1-21/33 Sequence Identity: 42% (9 aa) EGYSPLHLALLLNHIQLAKYL .|..||||| . .|.. .|.| DGFTPLHLACRCGHTEVVKML |
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| Ank | GL50803_11775.AA | Ank | 475-506 | 18 | 1.35694 | 6.4 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 475-506 Range on HMM: 1-21/33 Sequence Identity: 18% (6 aa) DGKTALIKAVLNYNEGLPAGQEDVNLAIIRLL || |.| |... .. ....| DGFTPLHLACRCG-----------HTEVVKML |
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| Ank | GL50803_11775.AA | Ank | 517-537 | 33 | 0.007607 | 14.52 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 517-537 Range on HMM: 1-21/33 Sequence Identity: 33% (7 aa) RGRTALMYAAECGYLAAIDVL |.|.|..|..||.. . | DGFTPLHLACRCGHTEVVKML |
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| Ank | GL50803_11775.AA | Ank | 612-629 | 22 | 0.403439 | 8.3 | Pfam | 1-18 (33) | Show / Hide |
Range on Protein: 612-629 Range on HMM: 1-18/33 Sequence Identity: 22% (4 aa) NGNTALMHCVIHDRPEFI .|.|.|. ......| . DGFTPLHLACRCGHTEVV |
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| Ank | GL50803_11775.AA | Ank | 643-666 | 20 | 6.279172 | 4.0 | Pfam | 1-24 (33) | Show / Hide |
Range on Protein: 643-666 Range on HMM: 1-24/33 Sequence Identity: 20% (5 aa) TGHSAMMLAVQLERRACFEALIKH | .. .||.. . . . |..| DGFTPLHLACRCGHTEVVKMLLQH |
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| Ank | GL50803_11775.AA | Ank | 674-706 | 21 | 2.081199 | 5.73 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 674-706 Range on HMM: 1-33/33 Sequence Identity: 21% (7 aa) SGMTALMMCASQGLRPYVNRLLNIETNIFNGTW |.|.|.. .. | | ||. .. . DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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| Ank | GL50803_11775.AA | Ank | 767-784 | 33 | 0.248348 | 9.06 | Pfam | 1-18 (33) | Show / Hide |
Range on Protein: 767-784 Range on HMM: 1-18/33 Sequence Identity: 33% (6 aa) SGYTPLMFAAQQANINAV |.|||. |.. ... | DGFTPLHLACRCGHTEVV |
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| Ank | GL50803_11775.AA | Ank | 798-820 | 34 | 0.014221 | 13.54 | Pfam | 1-23 (33) | Show / Hide |
Range on Protein: 798-820 Range on HMM: 1-23/33 Sequence Identity: 34% (8 aa) HGFTALIYATRVKSLECCRLLVD .|||.| .| | ..|....|.. DGFTPLHLACRCGHTEVVKMLLQ |
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| Ank | GL50803_11775.AA | Ank | 981-992 | 41 | 0.992449 | 6.89 | Pfam | 1-12 (33) | Show / Hide |
Range on Protein: 981-992 Range on HMM: 1-12/33 Sequence Identity: 41% (5 aa) SGETALMLAAKS |.|.|.||... DGFTPLHLACRC |
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| Ank | GL50803_11775.AA | Ank | 1077-1109 | 24 | 58.157131 | 0.51 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 1077-1109 Range on HMM: 1-33/33 Sequence Identity: 24% (8 aa) SAYTALNICIYCGKNTLIPLFLPYEADIEIHDK .|.| . ..|| . ..| . ||. ..|. DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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| Ank | GL50803_11775.AA | Ank | 1249-1281 | 36 | 1.1e-05 | 24.81 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 1249-1281 Range on HMM: 1-33/33 Sequence Identity: 36% (12 aa) KGETALMLAARSGSEAVVDILLNYEAEMQDNNK |.|.|.||.|.|.. || ||.. |. .. DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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| Ank | GL50803_11775.AA | Ank | 1312-1330 | 31 | 2.72115 | 5.31 | Pfam | 1-19 (33) | Show / Hide |
Range on Protein: 1312-1330 Range on HMM: 1-19/33 Sequence Identity: 31% (6 aa) CELSPLMLAVLEGDIKTVS . .||.||.. |... |. DGFTPLHLACRCGHTEVVK |
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| Ank | GL50803_11775.AA | Ank | 1342-1364 | 34 | 3.424163 | 4.95 | Pfam | 1-20 (33) | Show / Hide |
Range on Protein: 1342-1364 Range on HMM: 1-20/33 Sequence Identity: 34% (8 aa) SGMTALHMAIYLRQQAHANLLKM |.|.||.|.. |.. .|| DGFTPLHLACRCG---HTEVVKM |
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| Ank | GL50803_11775.AA | Ank | 1399-1417 | 31 | 12.751064 | 2.89 | Pfam | 1-19 (33) | Show / Hide |
Range on Protein: 1399-1417 Range on HMM: 1-19/33 Sequence Identity: 31% (6 aa) LGCTELHRAAIQNNSQQVR |.| || |.. .. . |. DGFTPLHLACRCGHTEVVK |
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| Ank | GL50803_11775.AA | Ank | 1429-1461 | 27 | 0.00267 | 16.16 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 1429-1461 Range on HMM: 1-33/33 Sequence Identity: 27% (9 aa) NGRTSLMEAALAGSLDAAKILVDHEHGMRARAR .|.| |. |.. |... .| |..| |. . DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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| Ank | GL50803_11775.AA | Ank | 1470-1491 | 36 | 0.000925 | 17.82 | Pfam | 1-22 (33) | Show / Hide |
Range on Protein: 1470-1491 Range on HMM: 1-22/33 Sequence Identity: 36% (8 aa) DEATALMFAAAAGHESIVRLLI | |.|. |. ||...|..|. DGFTPLHLACRCGHTEVVKMLL |
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| Ank | GL50803_11775.AA | Ank | 1502-1524 | 34 | 0.000364 | 19.28 | Pfam | 1-23 (33) | Show / Hide |
Range on Protein: 1502-1524 Range on HMM: 1-23/33 Sequence Identity: 34% (8 aa) NGKTALMAAAAAGHLSTLKLLID .| |.|. |. ||.. .|.|.. DGFTPLHLACRCGHTEVVKMLLQ |
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| Ank | GL50803_11775.AA | Ank | 1533-1558 | 26 | 0.088287 | 10.68 | Pfam | 1-26 (33) | Show / Hide |
Range on Protein: 1533-1558 Range on HMM: 1-26/33 Sequence Identity: 26% (7 aa) NGWTALMSVVSKQYVDCVAPLLEKEA .|.|.|. ... ....| ||.. | DGFTPLHLACRCGHTEVVKMLLQHGA |
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| Ank | GL50803_11775.AA | Ank | 1564-1584 | 28 | 1.142098 | 6.67 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 1564-1584 Range on HMM: 1-21/33 Sequence Identity: 28% (6 aa) QGNCALVTAISNGNMDIVRVL |. .| |...|....|. | DGFTPLHLACRCGHTEVVKML |
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