Gene GL50803_104150 (G.lamblia)
GL50803_104150
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| GL50803_104150.AA | Protein | None | 678 | None | Fasta, JSON |
| GL50803_104150.kin_dom | Protein Kinase Domain | None | 288 | None | Fasta, JSON |
Protein domains of GL50803_104150.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| S_TKc | GL50803_104150.AA | S_TKc | 22-309 | 28 | 4.7e-82 | 279.84 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 22-309
Range on HMM: 1-231/231
Sequence Identity: 28% (87 aa)
YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYDKFVTEVTIHRGLVHPNICRVLNVFKDQMNYYIILEKCNG--GTLTDLIRRRKH---
|. ....|||.|. || ...... .|.|| . ... |. |.. ||||.. . || | ..|...| |.| |.| |.|..|..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL
---LTETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDVKVGDFGLAVKCETPEELHWTMCGTPNFLPSEVIYSHIMKRKASGRGPDPNLDED
..| .|||. . |..|| |.|.. |||||.| .||.| | .|..||||| . |.||||.... ||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---------------------
CVNLCHQLLPAYSGQGHSF-SADMWSFGCLVFSMIYGRPPFEAADIKTTYKRIVRCDFSFPGSISVSEDLKNFIKGLLTPDPRKRFTVKECLD-------
|... ..|.||.||... |..|.|||. ......|.|. |...|.||...|. ||.|| |. |.|
---------------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC
HSWL
| |.
HPWF
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| Kinase | GL50803_104150.AA | CAMK | 27-309 | 19 | 6.6e-81 | 260.29 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 27-309
Range on HMM: 1-425/425
Sequence Identity: 19% (85 aa)
LLGKGGFAYVYEFHDVNSD------------SSYACKITPRSALQK-------------------------KKYYDKFVTEVTIHRGLV-------HPNI
||.|.|. |.. . |. .|.|| ... |.. | ... |. |.. | ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
CRVLNVFKD-------------------QMNYYIIL---EKCNGG----TLTDLIRRRKH---------------LTETEARFFSKRILNALWYLHDLYI
.. . |. | ....|... | | || | | |..... .|| |||.. . |. |. |.|.. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
IHRDIKTSNIFLMED-----------------FDVKVGDFGLAVKCET-----------------------PEELHWTMCGTPNFLP-SEVIYSHIMKRK
.|||.| || | .. ...|. |||.| |.. . .. .|.|||| . . ||. . .. .
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
ASGRGPDPNLDEDCVNLCHQLLPAYSGQGHSFSADMWSFGCLVFSMIYGRPPFEAA-------------DIKTTYKRIVRCDFSFPGS------------
. . . .......|||| |.. . | |.|||.. ... ....| .....|| .
Q-N-A-T----------------DEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPE
----ISVS------EDLKNFIKGLLTPDPRKRFTVKECLDHSWL
|| . .. |..|...|..|| ||.|...||.| |.
WWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
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| Pkinase | GL50803_104150.AA | Pkinase | 22-309 | 28 | 4.3e-80 | 277.19 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 22-309
Range on HMM: 1-293/293
Sequence Identity: 28% (94 aa)
YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYDKFV-TEVTIHRGLVHPNICRVLNVFKDQMNYYIILEKCNGG----TLTDLIR--RR
|. |. .|.|.|. ||. |.... .|.|| ... ..| . .. .|. |.. | ||||.| . .| | ..|...| |.|| | |.|. |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH
KHL--TETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDV----KVGDFGLAVKC-ETPEELHWTMCGTPNFLPSEVIYSHIMKRKASGRGPD
. . .| |..|. . || .| |.|. |||||.| .||.. .. .. |..||||| . . . . .| ||||.... |||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR--------------
PNLDEDCVNLCHQLLPAYSGQGHSFSADMWSFGCLVFSMIYGRPPFEAA------DIKTTYKRIVRCDFSFPGSISVS-------------------EDL
.||... ..||||.||... |. ||||| . | . ..|| .....|. . . | |..
------------------GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEEC
KNFIKGLLTPDPRKRFTVKECLDHSWL
| |||..|..|| || | ...| | |.
KDFIKWCLCKDPKKRPTAEQILQHPWF
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| Kinase | GL50803_104150.AA | PLK | 22-186 | 46 | 8.8e-77 | 249.58 | In-house | 1-166 (258) | Show / Hide |
Range on Protein: 22-186 Range on HMM: 1-166/258 Sequence Identity: 46% (77 aa) YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYDKFVTEVTIHRGLVHPNICRVLNVFKDQMNYYIILEKCNGGTLTDLIRRR-KHLTET |. |..||||||| .||. |. .. || |. |.| .||.. ..| |. ||| | |||| . ..| |. | || || |....| ....|| |.|||. YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP EARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDVKVGDFGLAVKCETPEELHWTMCGTPNF |.|.. | ..| |||. |||||.| .|.|| .. ||.||||||...| ..| . |||||||. EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNY |
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| Kinase | GL50803_104150.AA | PLK-Unclassified | 22-185 | 45 | 1.9e-67 | 230.42 | In-house | 1-171 (264) | Show / Hide |
Range on Protein: 22-185 Range on HMM: 1-171/264 Sequence Identity: 45% (77 aa) YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYDKFVTEVTIHRGLVHPNICRVLNVFKDQMNYYIILEKCNGGTLTDLIRRR------- |. |..||||||| .|.. .. . || || | | |.|.. . | | || | |.|| . . .| |. | || || |..||| ..|.|| YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK KHLTETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDVKVGDFGLAVKCETPEELHWTMCGTPN | |||.|..... |..|| |||. ||||| | |||| .. || .|||||.| | .| | ||||| KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPN |
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| Kinase | GL50803_104150.AA | PLK1 | 22-192 | 45 | 2.3e-62 | 203.68 | In-house | 1-171 (253) | Show / Hide |
Range on Protein: 22-192 Range on HMM: 1-171/253 Sequence Identity: 45% (77 aa) YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYDKFVTEVTIHRGLVHPNICRVLNVFKDQMNYYIILEKCNGGTLTDLIRRRKHLTETE |. |. ||||||| ||..|.. . .| |. |.| | |.. || |..||| | |..| .. . | |. | ||.|| |. | .| .||| .|| | YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE ARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDVKVGDFGLAVKCETPEELHWTMCGTPNFLPSEVI .|.. . |... |||.. |||||.| |.|| ....||.|||||| ||| | |.|||||.. ||. CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVL |
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| Kinase | GL50803_104150.AA | PLK2 | 22-192 | 43 | 2.5e-56 | 179.79 | In-house | 1-175 (257) | Show / Hide |
Range on Protein: 22-192 Range on HMM: 1-175/257 Sequence Identity: 43% (76 aa) YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYDKFVTEVTIHRGLVHPNICRVLNVFKDQMNYYIILEKCNG----GTLTDLIRRRKHL |. |||||||||| || | . . || || |.| | . | |. .|| | |..| . | |. | ||.|| | . |.|| YCRGKLLGKGGFARCYEMTDMDTHYVYAVKIVPHSRVAKPHQREKMEREIELHRQLRHRHIVQFHHHFEDRDNIYILLEYCSRQVPLKSMAHMWKVRHHL TETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDVKVGDFGLAVKCETPEELHWTMCGTPNFLPSEVI || | |.. . |. | |||. ||||| | .| |. . ||.|||||| . | .|. | |||||||.. ||. TEPEVRYYMRQIVSGLRYLHQQCIIHRDLKLGNFFINDNMEVKIGDFGLAARLEPEEHCHRTMCGTPNYIAPEVL |
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| Kinase | GL50803_104150.AA | SAK | 22-192 | 39 | 6.9e-44 | 147.2 | In-house | 1-172 (254) | Show / Hide |
Range on Protein: 22-192 Range on HMM: 1-172/254 Sequence Identity: 39% (68 aa) YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYDKFVTEVTIHRGLVHPNICRVLNVFKDQMNYYIILEKCNGGTLTDLIRRR-KHLTET |. ..|||||||| || . . | |. . ..|| .. || || | || | . | |.|. |..|| | | . ...| . ||. YQVQHLLGKGGFACVYRAKCIHTHQEVAIKMIDKKLMQKTGMVQRVRNEVEIHCQLKHPSILELYNYFEDNNYVYLVLEMCHNGEMHRYMKHRMRPFTEE EARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDVKVGDFGLAVKCETPEELHWTMCGTPNFLPSEVI ||| | ..|. . ||| |.|||. ||| | | ..|. ||||| . . |.| |.|||||||.. |.. EARHFMHQIVIGMLYLHSHGIMHRDLTLSNILLTRDMHCKIADFGLATQLKMPHEKHYTMCGTPNYISPEIA |
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| Kinase | GL50803_104150.AA | CAMKL | 22-186 | 29 | 3e-43 | 135.77 | In-house | 1-199 (297) | Show / Hide |
Range on Protein: 22-186 Range on HMM: 1-199/297 Sequence Identity: 29% (58 aa) YRPGKLLGKGGFAYVYEFHD-VNSDSSYACKITPRSALQKKKYYDKF------------VTEVTIHRGLV---HPNICRVLNVFKDQMN------YYIIL || || ||||.|. | .. . .| || .. .... . .| |. |.. | ||||.. . |. .. . .|... YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EKCNGGT--LTDLIRRRKH----LTETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFD--VKVGDFGLAVKCET----PEELHWTMCGTPNF | | || | | |....| ..| |||.. . |. |. |.|.. |.||||| || | |. . .|. |||.. ... |... | ||.|.. EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY |
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| Kinase | GL50803_104150.AA | CAMK-Unique | 22-192 | 23 | 3.1e-40 | 130.41 | In-house | 1-261 (363) | Show / Hide |
Range on Protein: 22-192
Range on HMM: 1-261/363
Sequence Identity: 23% (61 aa)
YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYD-----------------KFVTEVTIHRGLVHPNICRVLNV----FKDQM-------
|. ....|.|.| ||| .| .|||. . . ||.. |. |. | . . |||| ... . | |
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------NYYIILEKCNGGTLTDLIRR--------------------RKHLTE--TEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFD-----
..||..| |.||.| |.| . . |..| ....| . ..| |. |.|.. |.|||.| || . . |.
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH
-----------VKVGDFGLAVKCETPEELH--WTMCGTPNFLPS--------------EVI
.|. ||||... .. .. | |||||| .. |||
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVI
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| Kinase | GL50803_104150.AA | Ciliate-E2 | 22-192 | 23 | 1.2e-38 | 130.22 | In-house | 1-259 (365) | Show / Hide |
Range on Protein: 22-192 Range on HMM: 1-259/365 Sequence Identity: 23% (63 aa) YRPGKLLGKGGFAYVYEFHDVNSDSSYA----------------CKITPRSALQKKKYYDKFV-TEVTIHRGLV----------------HPNICRVLNV | |..|.|.|. ||. . . . .| .|| ..||. ... | | | . ||||.. . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FK--DQMNYYIILEKCNGGTLTDLIRRRKH-----------LTETEARFFSKRILN---------------ALWYLHDLY-IIHRDIKTSNIFLMEDFDV |. |. |.|...| |.||.| |.|. .|. .|| |.....| ||. || ||| ||||||| .||.. . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KVGDFGLAVKCETP-------------------------------EELHWTMCGTPNFLPSEVI |. ||||. |. .. .....| ||||.... |.. KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEIL |
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| Kinase | GL50803_104150.AA | ULK | 22-167 | 31 | 9.5e-38 | 131.54 | In-house | 1-185 (324) | Show / Hide |
Range on Protein: 22-167 Range on HMM: 1-185/324 Sequence Identity: 31% (58 aa) YRPGKLLGKGGFA-YVYEFHDVNS---DSSYACKITPRSALQKKKYY-------DKFVTEVTIHRGLV---HPN--ICRVLNVFKDQ--MNYYIILEKCN | . |||| |. .||. .... . .|||. ... ..|||. ... |. | . | ||| |.. . .|... |.|||.| || YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN GGTLTDLIRRRKH---------LTETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFD------------VKVGDFGLA ||.| ..| ..|. |.| ||. | | |.|.. .||. ||||||| .|| . ... .|..|||.| GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA |
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| Kinase | GL50803_104150.AA | PLK | 228-309 | 40 | 1.6e-34 | 109.91 | In-house | 177-258 (258) | Show / Hide |
Range on Protein: 228-309 Range on HMM: 177-258/258 Sequence Identity: 40% (33 aa) QGHSFSADMWSFGCLVFSMIYGRPPFEAADIKTTYKRIVRCDFSFPGSISVSEDLKNFIKGLLTPDPRKRFTVKECLDHSWL ||||. .|.||.|| . .. |.||||..|.|.|||||. ...||| .. .| .|..|. .| ..|..|.| .. |.| .. QGHSYEVDCWSLGCIMYTLLIGKPPFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF |
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| Kinase | GL50803_104150.AA | PLK-Unclassified | 228-309 | 39 | 4e-31 | 109.74 | In-house | 183-264 (264) | Show / Hide |
Range on Protein: 228-309 Range on HMM: 183-264/264 Sequence Identity: 39% (32 aa) QGHSFSADMWSFGCLVFSMIYGRPPFEAADIKTTYKRIVRCDFSFPGSISVSEDLKNFIKGLLTPDPRKRFTVKECLDHSWL ||||. |.||||| . .. |.||||. |.|.|||.| ..||| . .| .|..|. |...| .|.| . ..|... QGHSYEVDCWSFGCILYTLLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY |
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| Kinase | GL50803_104150.AA | CAMKL | 232-309 | 26 | 4.2e-24 | 73.67 | In-house | 215-297 (297) | Show / Hide |
Range on Protein: 232-309 Range on HMM: 215-297/297 Sequence Identity: 26% (23 aa) FSADMWSFGCLVFSMIYGRPPFEAA--------DIKTTYKRIVRCDFSFPGSISVSEDLKNFIKGLLTPDPRKRFTVKECLDHSWL . .|.|| | . . |..|. ||... .| . |..| .. . .| ..|| |....|...|...| ||.|... . | |. PKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | GL50803_104150.AA | Ciliate-E2 | 227-309 | 25 | 9.8e-24 | 78.34 | In-house | 270-365 (365) | Show / Hide |
Range on Protein: 227-309 Range on HMM: 270-365/365 Sequence Identity: 25% (27 aa) GQGHSFSADMWSFGCLVFSMIYGRPPFEAADIKTTYKRIVRCDFSFP----------------GSISVSEDLKNFIKG----LLTPDPRKRFT-VKECLD ..|.....|.||.|.. . |..|.||| .. | |...|| ..|.. |..|| .| || ||.| ...|. QKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN HSWL | |. HPWF |
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| Kinase | GL50803_104150.AA | CAMK-Unique | 234-309 | 27 | 1.5e-22 | 71.06 | In-house | 274-363 (363) | Show / Hide |
Range on Protein: 234-309 Range on HMM: 274-363/363 Sequence Identity: 27% (25 aa) ADMWSFGCLVFSMIYGRPPFEAADIK--------TTYKRIVRCDF-SFPG---SIS--VSEDLKNFIKGLLTPDPRKRFTVKECLDHSWL .| || | . ..|. |.|||...... ....| .|. .|. ... .|. .|.|.|...| || .| . || |.|.|. SDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI |
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| Kinase | GL50803_104150.AA | PLK1 | 228-309 | 35 | 4.3e-22 | 69.18 | In-house | 174-253 (253) | Show / Hide |
Range on Protein: 228-309 Range on HMM: 174-253/253 Sequence Identity: 35% (29 aa) QGHSFSADMWSFGCLVFSMIYGRPPFEAADIKTTYKRIVRCDFSFPGSISVSEDLKNFIKGLLTPDPRKRFTVKECLDHSWL .|||| |.|| ||... ...|.||||. .| ||.|| ..... | ..|. ...|. .| ||| .| |... | .. KGHSFEVDIWSIGCIMYILLFGQPPFETKCLKETYSRIKKNEYRIP--SHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF |
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| Kinase | GL50803_104150.AA | PLK2 | 228-309 | 35 | 1.2e-20 | 62.91 | In-house | 178-257 (257) | Show / Hide |
Range on Protein: 228-309 Range on HMM: 178-257/257 Sequence Identity: 35% (29 aa) QGHSFSADMWSFGCLVFSMIYGRPPFEAADIKTTYKRIVRCDFSFPGSISVSEDLKNFIKGLLTPDPRKRFTVKECLDHSWL ||||. .| |. || . | ||||||.|. | ||..| . .| . | . . | .| |||. | . ..| QGHSCESDIWALGCIMYTMLCGRPPFETANLKETYRCIRHNHYHMPTHLSPP--ARHLIARMLSPDPEDRPSLDHIIRHDFF |
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| Kinase | GL50803_104150.AA | ULK | 227-309 | 24 | 2.1e-19 | 65.58 | In-house | 221-324 (324) | Show / Hide |
Range on Protein: 227-309 Range on HMM: 221-324/324 Sequence Identity: 24% (26 aa) GQG----HS-FSADMWSFGCLVFSMIYGRPPFEAADIKTTYK------------RIVRCD--FSFP---GSISVSEDLKNFIKGLLTPDPRKRFTVKECL ||| .. . .|.||.||. . |.||..||.. . ..|. | .. . || .. .|...|..|...|. |...|.. | . GQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIF DHSWL .| |. NHPWF |
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| Kinase | GL50803_104150.AA | SAK | 230-309 | 27 | 2.2e-17 | 55.54 | In-house | 177-254 (254) | Show / Hide |
Range on Protein: 230-309 Range on HMM: 177-254/254 Sequence Identity: 27% (22 aa) HSFSADMWSFGCLVFSMIYGRPPFEAADIKTTYKRIVRCDFSFPGSISVSEDLKNFIKGLLTPDPRKRFTVKECLDHSWL | .|.|| ||... .. |||||. .|.| ... .. | .|. . . |. .| .| | |.. |.| .. HGLQSDVWSLGCMLYTLLIGRPPFDTDAVKNTLNKVMMAEYIMPAHLSM--EAQDLIHKMLRKNPHERITLSTVLCHPFM |
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| Kinase | GL50803_104150.AA | TyrKc | 22-309 | 20 | 2.6e-10 | -55.96 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 22-309
Range on HMM: 1-280/280
Sequence Identity: 20% (66 aa)
YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYDKFVTEVTIHRGL--VHPNICRVLNVFKDQ-------MNYYIILEKCNGGTLTDLIR
. || || | | ||. . | | .| | | | . | |||| | . | .| ..|..| . .| | | .|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR
RRKH-LTETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDVKVGDFGLAVKCETPEELHWTMCGTPNFLPSEVIYSH-IMKRKASGRGPDPNL
.... |. . |. | . |||. .||||. . |. . |.. ||..||||. . ||.. . .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRD----------------------IYDDDQQG---------ESK
DEDCVN---LCHQLLP-------AYSGQGHSFSADMWSFGCLVFSMI-YGRPPFEA-----ADIKTTYKRIVRCDFSFPGSI-------SVSEDLKNFIK
| . .. .|| . .. | |||| . . . || .| . . . .... . . . .... . .|
DYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMK
GLLTPDPRKRFTVKECLDHSWL
|| .| | .|. |. .
QCWHEDPEDRPTFSEI--HECF
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| Kinase | GL50803_104150.AA | Pkinase_Tyr | 79-167 | 32 | 4e-05 | 17.97 | Pfam | 63-158 (270) | Show / Hide |
Range on Protein: 79-167 Range on HMM: 63-158/270 Sequence Identity: 32% (31 aa) HPNICRVLNVFK-DQMN--YYIILEKCNGGTLTDLIRR----RKHLTETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDVKVGDFGLA |||| | . | .. .||..| . .| | | |. ...|| . .. | ... ||.. .||||. . |. . |.. ||..||||| HPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA |
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| POLO_box | GL50803_104150.AA | POLO_box | 442-478 | 46 | 8.8e-10 | 39.73 | Pfam | 1-39 (74) | Show / Hide |
Range on Protein: 442-478 Range on HMM: 1-39/74 Sequence Identity: 46% (18 aa) YSNRYGFAYQISNGSIGVI-FNDESAAILSPNAL-IVDY |...||. || |||...| ||| . ||.||. |.| YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTY |
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| POLO_box | GL50803_104150.AA | POLO_box | 575-636 | 19 | 0.000475 | 18.56 | Pfam | 7-74 (74) | Show / Hide |
Range on Protein: 575-636 Range on HMM: 7-74/74 Sequence Identity: 19% (13 aa) LCLLFNTKVFQVN-FADHSKVV--VAHR-SVTFMS--EKREIYTYPSEYLKDDRFSFKELRRRVDRAR . ..... .||| | ||.|.. . .||... .... .||| . . . . ..|.... .. IMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTYIDHDPNWQRQTYPLSTILEHGCYPEDLQKKLTYLK |
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