Gene TVAG_120800 (T.vaginalis)

TVAG_120800

Species: T.vaginalis
Alias: TvagK1045, TVAG_120800
External Links:
Annotation:

Classification

Group: Other
Family: Other-Tvag3

Sequence

Name Sequence Type Origin Length Description Download
TVAG_120800.AA Protein None 2047 None Fasta, JSON
TVAG_120800.kin_dom Protein Kinase Domain None 450 None Fasta, JSON

Protein domain

Protein domains of TVAG_120800.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

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Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
IQ TVAG_120800.AA IQ 8-28 42 2.2e-05 21.29 Pfam 1-21 (21) Show / Hide 
Range on Protein: 8-28
Range on HMM: 1-21/21
Sequence Identity: 42% (9 aa)

KLAAIKIQSVFRGFMYRNNIK
. ||||||...||.. | . .
HRAAIKIQAWWRGYLARKHYR
IQ TVAG_120800.AA IQ 6-28 43 3.8e-05 24.35 SMART 1-23 (23) Show / Hide 
Range on Protein: 6-28
Range on HMM: 1-23/23
Sequence Identity: 43% (10 aa)

KMKLAAIKIQSVFRGFMYRNNIK
.|. |||.||. .||.. | . |
RMHRAAIIIQAWWRGYLARKRYK
IQ TVAG_120800.AA IQ 34-54 33 7.8e-05 19.53 Pfam 1-21 (21) Show / Hide 
Range on Protein: 34-54
Range on HMM: 1-21/21
Sequence Identity: 33% (7 aa)

NKAATVIQKCFRKFRARMIME
 .||..||...| ..||  ..
HRAAIKIQAWWRGYLARKHYR
IQ TVAG_120800.AA IQ 32-54 30 0.004613 17.42 SMART 1-23 (23) Show / Hide 
Range on Protein: 32-54
Range on HMM: 1-23/23
Sequence Identity: 30% (7 aa)

KKNKAATVIQKCFRKFRARMIME
....||..||...| ..||  . 
RMHRAAIIIQAWWRGYLARKRYK
Kinase TVAG_120800.AA STE20 73-95 40 0.050602 3.54 In-house 46-70 (288) Show / Hide 
Range on Protein: 73-95
Range on HMM: 46-70/288
Sequence Identity: 40% (10 aa)

KKKHEIQKEINHLKKFDH--ILTYY
.....|||||. .|...|  | .||
DEWEDIQKEISIMKQCKHPNIVKYY
Kinase TVAG_120800.AA FRAY 1207-1230 58 1.8e-07 18.95 In-house 254-277 (277) Show / Hide 
Range on Protein: 1207-1230
Range on HMM: 254-277/277
Sequence Identity: 58% (14 aa)

IGLCLQLDPNKRPTVQELIKFNVF
|  ||| || ||||  || |  .|
IEKCLQKDPSKRPTASELLKHKFF
Kinase TVAG_120800.AA Ciliate-E2-Unclassified 1002-1105 21 2e-07 21.86 In-house 148-269 (352) Show / Hide 
Range on Protein: 1002-1105
Range on HMM: 148-269/352
Sequence Identity: 21% (27 aa)

IISKILQALKRLHARN-VVCRTVVPSNIFIDSANN--TTQIGSIFDCQHLLPNKSSTVLPL-------PSDFAQPS---NPFL----PPEYYHKPQYEHT
..  |||.|. ||  | .. |   |.||..|. ..     |   . . ..  |  ..           ... ..     . ..    .||.. . .|.|.
YFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHS

--TKFDVWQIGVLLLYILTGNLP
   | |.|  ||.| ..|.|..|
KAYKCDIWSLGVILYEMLFGYYP
Kinase TVAG_120800.AA MAK 1203-1230 50 2.3e-07 19.03 In-house 325-352 (352) Show / Hide 
Range on Protein: 1203-1230
Range on HMM: 325-352/352
Sequence Identity: 50% (14 aa)

LIEVIGLCLQLDPNKRPTVQELIKFNVF
.||..  .|| ||||||| |.. |.  |
AIELMKDMLQWDPNKRPTAQQCCKYPYF
Kinase TVAG_120800.AA Ciliate-E2 1069-1105 27 5.7e-07 19.94 In-house 252-295 (365) Show / Hide 
Range on Protein: 1069-1105
Range on HMM: 252-295/365
Sequence Identity: 27% (12 aa)

PFLPPEYYHKPQYE-------HTTKFDVWQIGVLLLYILTGNLP
....|| . . .|.       ...| |.| .||.| . |.|..|
GYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP
S_TKc TVAG_120800.AA S_TKc 902-1230 12 9.8e-07 -78.13 SMART 1-231 (231) Show / Hide 
Range on Protein: 902-1230
Range on HMM: 1-231/231
Sequence Identity: 12% (46 aa)

WSTTKLFG----------RDSD-SHNFLMKWILPRGYFDNNAVWNHFKFVSNLSNASHFVSTHVYGHKTDVINKTTHLVVTQNTRSL---PLSHFLTVHS
.   .. |          |. .  . . .| |        . ...  .  ..     |    . |..  |     .|| .     .     | ...  . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK----HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRG

FLGS-TQNRISTARIIISKILQALKRLHARNVVCRTVVPSNIFIDSANNTTQI-------GSIFDCQHLLPNKSSTVLPLPSDFAQPSNPFLPPEYYHKP
  |   .    .|| ..  |..||. .| .... | . |.||..|.     .|         ..                 . |    . ...||     
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-----------------TTFCGTPW-YMAPEVL---

QYEHTT-KFDVWQIGVLLLYILTGNLPPSYGTELLSRLNQNDIPKRVRFTHDFNLEEPPLYPDIGFFYDWMKGATVVPPTERMYGECGEIFFVSELNNPA
   ... | |.| .|..|   |.|  | .   ... ..                                                              
--GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG------------------------------------------------------------

TCLDIEYYKFAPLNCKEDQEELHKLIEVIGLCLQLDPNKRPTVQELIK-------FNVF
                      . ... |  ||| ||.||||. |. .          |
---------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TVAG_120800.AA STE 1202-1230 41 2e-06 18.53 In-house 329-359 (359) Show / Hide 
Range on Protein: 1202-1230
Range on HMM: 329-359/359
Sequence Identity: 41% (13 aa)

KLIEVIGLCLQLDPNKRPTVQELIK--FNVF
.... | .||| |||||||...|.|     .
EFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase TVAG_120800.AA NEK 1202-1230 27 3e-06 18.24 In-house 258-286 (286) Show / Hide 
Range on Protein: 1202-1230
Range on HMM: 258-286/286
Sequence Identity: 27% (8 aa)

KLIEVIGLCLQLDPNKRPTVQELIKFNVF
.| ..| ..|| || .||........   
DLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase TVAG_120800.AA Dicty3 1205-1225 47 7e-06 15.09 In-house 331-351 (351) Show / Hide 
Range on Protein: 1205-1225
Range on HMM: 331-351/351
Sequence Identity: 47% (10 aa)

EVIGLCLQLDPNKRPTVQELI
. |  |.| |||.|. . |||
NFIQHCWQIDPNHRWDMHELI
Kinase TVAG_120800.AA TTK 1203-1230 35 8e-06 15.1 In-house 317-344 (344) Show / Hide 
Range on Protein: 1203-1230
Range on HMM: 317-344/344
Sequence Identity: 35% (10 aa)

LIEVIGLCLQLDPNKRPTVQELIKFNVF
||.|  .||...| ||... ||      
LIHVMKCCLYRNPKKRWSIPELLNHPFH
Kinase TVAG_120800.AA STE20 1207-1230 45 1.9e-05 16.2 In-house 265-288 (288) Show / Hide 
Range on Protein: 1207-1230
Range on HMM: 265-288/288
Sequence Identity: 45% (11 aa)

IGLCLQLDPNKRPTVQELIKFNVF
. .||| ||.||||...| |   .
VDKCLQKDPEKRPTASQLLKHPFI
Kinase TVAG_120800.AA TBCK 1202-1230 44 6.7e-05 13.37 In-house 318-346 (346) Show / Hide 
Range on Protein: 1202-1230
Range on HMM: 318-346/346
Sequence Identity: 44% (13 aa)

KLIEVIGLCLQLDPNKRPTVQELIKFNVF
.||. |  |||  | |||.  || .  .|
WLIQIIRKCLQMCPMKRPSPTELMEHPMF
Kinase TVAG_120800.AA TBCK 1002-1035 35 8.9e-05 12.91 In-house 85-118 (346) Show / Hide 
Range on Protein: 1002-1035
Range on HMM: 85-118/346
Sequence Identity: 35% (12 aa)

IISKILQALKRLHARNVVCRTVVPSNIFIDSANN
|.. ||..|  .| .. | | . |.|| .|. .|
IYYQILCGLSYMHKHHIVHRFLHPHNIYLDDNGN
Kinase TVAG_120800.AA Ciliate-E2 1210-1230 36 0.005214 6.15 In-house 344-365 (365) Show / Hide 
Range on Protein: 1210-1230
Range on HMM: 344-365/365
Sequence Identity: 36% (8 aa)

CLQLDPNKRPT-VQELIKFNVF
.|| ||.||.|  .....   |
MLQKDPEKRITGWEQILNHPWF
Kinase TVAG_120800.AA Pkinase 1203-1230 35 0.005794 11.56 Pfam 266-293 (293) Show / Hide 
Range on Protein: 1203-1230
Range on HMM: 266-293/293
Sequence Identity: 35% (10 aa)

LIEVIGLCLQLDPNKRPTVQELIKFNVF
....|  ||..||.|||| ... .   |
CKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase TVAG_120800.AA Ciliate-E2-Unclassified 1197-1230 25 0.014243 4.77 In-house 318-352 (352) Show / Hide 
Range on Protein: 1197-1230
Range on HMM: 318-352/352
Sequence Identity: 25% (9 aa)

QEELHKLIE-VIGLCLQLDPNKRPTVQELIKFNVF
..|   .|.  .  .|. .||||.| .....   |
SPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase TVAG_120800.AA Pkinase 1080-1105 30 0.482296 4.77 Pfam 186-211 (293) Show / Hide 
Range on Protein: 1080-1105
Range on HMM: 186-211/293
Sequence Identity: 30% (8 aa)

QYEHTTKFDVWQIGVLLLYILTGNLP
. ....| |.| .|..| . |.|..|
GQYYGPKVDMWSCGCILYEMLCGRPP