Gene 94534.m00165 (T.vaginalis)

94534.m00165

Species: T.vaginalis
Alias: TvagK0754, 94534.m00165
External Links:
Annotation:

Classification

Group: Other
Family: CAMKK

Sequence

Name Sequence Type Origin Length Description Download
94534.m00165.AA Protein None 354 None Fasta, JSON
94534.m00165.kin_dom Protein Kinase Domain None 272 None Fasta, JSON

Protein domain

Protein domains of 94534.m00165.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 94534.m00165.AA S_TKc 48-319 23 7.4e-60 206.08 SMART 1-231 (231) Show / Hide 
Range on Protein: 48-319
Range on HMM: 1-231/231
Sequence Identity: 23% (67 aa)

YVFLREIGSGAMSHVYEAVHTETGEHIAAKVYNLIQLCKPTLRSEPPPIDDVQKEIKIMMSIDHSYILSLIEAIEDDATRSLIIFMPFAQY--GSVQTLL
| .||.||.||.. || ..|..||.. | |. .                .....||.|... .| .|  |.....|    .| ..| ..    |.. ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYI

DKNQ-------MNQDEISICFLQIAYGLEELHSKNIVHRDIKNENFLCFQKDFYVLSDFSVSTILDDPDQKLEDTKGSPAFLSPEECSGEAFYPK-PADV
.|..       ..  ..   . ||. .|| .||..|.|||.| || |. .     ..|| ....|           |.| ...|| .     | | ..|.
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDW

WAYGVSLYLAVYKKLPFNLDQSNACPVANTVLLVTQNLETQTLQFPENADVDSFVEDLISQCLNKDPTQRPTFTEITK-------HTYF
|. |. ||  .. . ||            .. .. ...             ... . .|..||.|||..|||  |. .       | .|
WSCGCILYEMLCGYPPFP-----------QMQMMFKKIG-----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94534.m00165.AA CAMK 53-319 17 2.5e-55 176.4 In-house 1-425 (425) Show / Hide 
Range on Protein: 53-319
Range on HMM: 1-425/425
Sequence Identity: 17% (75 aa)

EIGSGAMSHVYEAVHTETG------------EHIAAKVYNLIQLCKPT---------LRSE----------PPPIDDVQKEIKIMMS-------IDHSYI
..|.|. . |....|..|.            .. |.|...  .| . .         .. .          |   . |..||.||..       .||  |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LSLIEAIEDDA---------TRS---------LIIFM---PFAQYG----SVQTLLDKN----------------QMNQDEISICFLQIAYGLEELHSKN
..|.|..||.          | |         ....|    ... |     .   . ..                 .. .| . .| ||. ... .||.|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDIKNENFLCFQKD----------------F-YVLSDFSVSTILDD-----------------------PDQKLEDTKGSPAFLS-PEECSG-----
|||||.| || |. ...                .   ..||  ....|.                       ..||...  |.|.. . ||  .|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------EAFYPKPADVWAYGVSLYLAVYKKLPFNLD-QSNACP----VANTVLLVTQNLETQ-TLQFPE---------------------NADVDSFV
        .  |....|.|. || ||  .  ..||. | ... |      .|   |  . .. . .   |.                     .  |.  .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQEC

EDLISQCLNKDPTQRPTFTEITKHTYF
 |||...|..||..|.| ... .|  .
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 94534.m00165.AA CAMKK 48-319 22 4.4e-53 166.6 In-house 1-396 (396) Show / Hide 
Range on Protein: 48-319
Range on HMM: 1-396/396
Sequence Identity: 22% (92 aa)

YVFLREIGSGAMSHVYEAVHTET-GEHIAAKVYNL----IQLCK--PTLRSEPP---------------PIDDVQKEIKIMMSIDHSYILSLIEAIEDDA
| ...|||.|.   |  |..... . | | |..|     ..| |   . |..|.               |.|.|..|| ||  ..| .|  |.| |.|  
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDPQ

TRSLIIF-MPFAQYGSVQTLLDKNQ--------------------------MNQDE---------------------ISICFLQIAYGLEELH-SKN---
 ... .  | ....|... . ...|                          |....                         |.... ||| || ...   
NDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKACS

----------------IVHRDIKNENFLCFQKD---FYVLSDFSVSTILDDPDQKLED-----------TKGSPAFLSPEECSGEAFYP-----------
                |.||||| .| |. . .     ...||.||.|... ||.| .           | | |||. || || |  ..           
YIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRFRF

----KPADVWAYGVSLYLAVYKKLPFNLDQSNACPVANTVLLVTQ---NLETQTLQFPE-----------NADVDSFVEDLISQCLNKDPTQRPTFTEIT
    |.||.|| ||.||  |..|.||.         .|. .         . . ..|||           . ..     ||| ..|.|.||.| | ..| 
IYCGKAADIWALGVTLYCFVFGKCPFW---------HNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIK

KHTYF
.|. .
VHPWV
Kinase 94534.m00165.AA CAMKL 48-319 26 7.5e-52 163.68 In-house 1-297 (297) Show / Hide 
Range on Protein: 48-319
Range on HMM: 1-297/297
Sequence Identity: 26% (79 aa)

YVFLREIGSGAMSHVYEAVH-TETGEHIAAKVYN--LIQLCKPTLRSEPP---PIDD-VQKEIKIMMSID---HSYILSLIEAIEDDAT----RSLIIFM
| .....| |. . |  |.|   |||. | |...   |..   ...  ..   . |. ...||.||....   |  | .| | ||.. .      . ..|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

PFAQYGS--VQTLLDKNQ-----MNQDEISICFLQIAYGLEELHSKNIVHRDIKNENFLCFQKD--FYVLSDFSVSTILDD----PDQKLEDTKGSPAFL
  .. |.   .  ..|.      |  .|    | ||  ... .||..||||||| || |  ...     ..||  |.. ..    |.|||.   |||.. 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPEECSG--EAFYPKPADVWAYGVSLYLAVYKKLPFNLDQSNACPVANTVLLVTQNLETQTLQFPENAD--VDSFVEDLISQCLNKDPTQRPTFTEITKH
.|| ..|  . .. ...|.|. || ||  |. .|||. |  |    ..     .  ... .. . ..    |.  ..|||.. |...|..|||  .| .|
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN-K--QGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH

TYF
  .
PWM
Kinase 94534.m00165.AA Ciliate-E2 48-319 20 1.2e-51 175.57 In-house 1-365 (365) Show / Hide 
Range on Protein: 48-319
Range on HMM: 1-365/365
Sequence Identity: 20% (78 aa)

YVFLREIGSGAMSHVYEAVHTETGEHIAAKVYNLIQLCKPT-------------LRSEPPPIDDVQKEIKIMM----------------SIDHSYILSLI
| |.. ||.|. . ||.. . .... .| |. .   . ...              . ..  |  . .||.||.                ...| .|. ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

EAIEDDATRSLIIFMPFAQYGSVQTLLDKN------------QMNQDEISICFLQIAY---------------GLEELHSKN-IVHRDIKNENFLCFQKD
|. ..  . .. . | ..|.|. . .. .|            ...  ||.  . ||..               .||.||||| |.||||| || |     
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

FYVLSDFSVSTILDDPDQ---------KLEDTK-----------------------GSPAFLSPEECSGEAF--------YPKPADVWAYGVSLYLAVYK
   ..||  |...||. |         .. . |                       |.| ...||  .|.          | . .|.|. || ||  ...
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

KLPFNLDQSNACPVANTVLLVTQNLETQTLQFP----------------ENADVDSFVEDLISQ----CLNKDPTQRPT-FTEITKHTYF
|.||                  |. . . ..||                .. ...  . |||..    .|.||| .|.| . .| .| .|
KPPF-----------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 94534.m00165.AA Pkinase 48-319 22 5e-46 163.84 Pfam 1-293 (293) Show / Hide 
Range on Protein: 48-319
Range on HMM: 1-293/293
Sequence Identity: 22% (70 aa)

YVFLREIGSGAMSHVYEAVHTETGEHIAAKVYNLIQLCKPTL-----RSEPPPIDDVQKEIKIMMSIDHSYILSLIEAIEDDATRSLIIFMPFAQYG---
|...| ||||... ||...|  ||.  | |. ..    .  .     .           ||.|| ...| .|. |... ||   ... . |.... |   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL----------SEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYV

-SVQTLLD---KNQM--NQDEISICFLQIAYGLEELHSKNIVHRDIKNENFLCFQKDFY----VLSDFSVSTIL-DDPDQKLEDTKGSPAFLSPEECSGE
 .  ...    .. .    .|.  ...||. ||| .||..|.|||.| ||.|. ...       ..|| ..  .   ... . .  |.| ...|| . | 
MDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGG

AFYPKPADVWAYGVSLYLAVYKKLPFNLDQSNACPVANTVLLVTQNLETQTLQFPENADVD-------------------SFVEDLISQCLNKDPTQRPT
  |....|.|..|. ||  . ...||  ..    .  .. . . ..     | |..  . .                   .   |.|. ||.|||..|||
QYYGPKVDMWSCGCILYEMLCGRPPFP-GHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT

FTEITKHTYF
...| .| .|
AEQILQHPWF
Kinase 94534.m00165.AA Meta 48-319 28 9.1e-35 97.79 In-house 1-287 (287) Show / Hide 
Range on Protein: 48-319
Range on HMM: 1-287/287
Sequence Identity: 28% (85 aa)

YVFLREIGSGAMSHVYEAVHTETGEHIAAKVYNLIQLCKPT--LRS---------------EPPPIDDVQKEIKIMMSIDHSYILSLIEAIEDDATRSLI
|.. .||| |.   |  | . |.  | | |. . . | | .   |                 . |.|.|..|| |.   ||  .  |.| . | .. .| 
YRLMEEIGKGSYGVVKLAYNEEDHHHYAMKILSKKKLLKQYGFMRRPPPRGNKPNQGGCIQPRNPLDRVYQEIAILKKLDHPNVVKLVEVLDDPNEDYLY

IFMPFAQYGSVQTLLDKNQMNQDEISICFLQIAYGLEELHSKNIVHRDIKNENFLCFQKDFYVLSDFSVSTILDDPDQKLED--TKGSPAFLSPEECSGE
. . . . |.|      | .  |     |  |  ||| ||   |.||||| .| |          || || . .. |  | .  | |.|||. || || |
MVFEYVEKGPVMEVPCDNPLSEDQAWSYFRDIVCGLEYLHYQKIIHRDIKPSNLLLNDDGHVKIADFGVSNEFEGDDAFLCNGSTAGTPAFMAPEACSEE

AFY---PKPADVWAYGVSLYLAVYKKLPFNLDQSNACPVA--NTVLLVTQNLETQTLQFPENADVDSFVEDLISQCLNKDPTQRPTFTEITKHTYF
.      . .|||| ||.||  |. . ||         ..  | ...  .   .. . |||. ..   . |.|.. | |.|..| .  ||  |.  
QNHFYCGRALDVWAMGVTLYCFVFGQCPF---------IDKTNYIMCLHDKIKNHPVMFPEQPEISEDLKDCIKRMLDKNPEHRIMIPEIKTHPWV
Kinase 94534.m00165.AA Ciliate-E2-Unclassified 48-319 20 1.1e-34 117.68 In-house 1-352 (352) Show / Hide 
Range on Protein: 48-319
Range on HMM: 1-352/352
Sequence Identity: 20% (73 aa)

YVFLREIGSGAMSHVYEAVHTETGEHI-----AAKVYNLIQLCKPTLRSEPPPIDDVQKEIK-------------IMMSIDHSYILSLIEAIEDDATRSL
| ... ||.|. . ||...| ...  .     . |. .  |. . .   |   . .  ...|             |. ...| .|. .... .|. .  .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQN--I

IIFMPFAQYGSVQTLLDKN-----------------QMNQDEISI------CFLQIAYGLEELHSKN-IVHRDIKNENFLCFQKD----FYVLSDFSVST
.| | ....|. .  . |.                 .. ... ..       | ||  ||| ||.|| |.||||| || | |...       ..||. | 
YIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENIL-FDNNGKNYYIKIIDFGISK

ILDDP---------------DQKLEDTKGSPAFL----SPEECSGEAFYP---KPADVWAYGVSLYLAVYKKLPFN---LDQSNACPVANTVL-----LV
 ....               .|.. .. |.| ..    .||   |.  .    . .|.|. || ||  .. ..||.    .|..    ... .      .
KYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-NNAYRKQL

TQNLETQTLQFPENA------DVDSFVEDLIS----QCLNKDPTQRPTFTEITKHTYF
 ||   . .|||.        ...  ..|.|.    ..|.|.| .|.|| .| .| .|
YQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 94534.m00165.AA ULK 48-319 22 9.5e-34 117.15 In-house 1-324 (324) Show / Hide 
Range on Protein: 48-319
Range on HMM: 1-324/324
Sequence Identity: 22% (72 aa)

YVFLREIGSGAMS-HVYEAVHTET---GEHIAAKVYNLIQLCKPTLRSE-PPPIDDVQKEIKIMMSID---HSY--ILSLIEAIEDDATRSLIIFMPFAQ
|.  ...|.|.    ||.. . .|   ....|.|. .. .. |  ...|    ..  ..||.||  ..   | .  |  |..  |..    . |.| . .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

YGSVQTLLDKNQ----------MNQDEISICFLQIAYGLEELHSKNIVHRDIKNENFLCFQKDFYV------------LSDFSVSTILDDPD---QKLED
 |  .... ||.           ...|. . | ||. |. |||..||.||||| .| |   .. .             ..||  . ..|...   |..  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

TK------GSPAFLSPEECS----GEAFYPKPADVWAYGVSLYLAVYKKLPFNLDQSNACPVANTVLLVTQ------NLETQTLQFP---ENADVDSFVE
..      |.| . .|.  .    .. .| . .|.|  |. .|  .| | ||. .  |         |. .        ..| .|||   ..  . . ..
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

DLISQCLNKDPTQRPTFTEITKHTYF
|||...| .|...| ...|| .|  |
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 94534.m00165.AA ULK 48-319 21 8.3e-33 111.89 In-house 1-329 (329) Show / Hide 
Range on Protein: 48-319
Range on HMM: 1-329/329
Sequence Identity: 21% (72 aa)

YVFLREIGSGAMSHVYEAVHTET----GEHIAAKVYNLIQLCKPTLRSE-PPPIDDVQKEIKIMMSID--------HSYILSLIEAIEDDATRSLIIFMP
|.  ...|.|.   ||.. . .|    .| .|.|.  . .. .    .|    .. ...|||||  ..        | .|  |..  |..    . |.| 
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FAQYGSVQTLLDKNQ-----------MNQDEISICFLQIAYGLEELHSKNIVHRDIKNENFLCFQKDFYV------------LSDFSVSTILDDP---DQ
. . |  .... ||.            ...|. . | ||. |. |||..||.||||| .| |   .. .             ..||  .  .|..   .|
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

KLEDTK------GSPAFLSPEECS----GEAFYPKPADVWAYGVSLYLAVYKKLPFNLDQSNACPVANTV-LLVTQNLE----------TQTLQFP---E
 .  ..      |.| . .|.  .    .. .| . .|.|  |. .|  .| | ||     .|.    .. . ......          .| ||||   .
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPF-----YAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGN

NADVDSFVEDLISQCLNKDPTQRPTFTEITKHTYF
.  . . ..|||...| .|...| ...|. .|  |
DPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 94534.m00165.AA STE 48-319 20 1.2e-32 112.61 In-house 1-359 (359) Show / Hide 
Range on Protein: 48-319
Range on HMM: 1-359/359
Sequence Identity: 20% (74 aa)

YVFLREIGSGAMSHVYEAVHT------ETGEH---------IAAKVYNLIQ------LCKPTLRSE-----PPPIDDVQKEIKIMMSID--HSYILSLIE
. ....||.||   || |..       .|||          .| |. || .      .  .  . |     .  .....||||||.  .  | .|   . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQ-EN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYG

AIEDDATR-----SLIIFMPFAQYGSVQTLLDKNQ---------------MNQDEISICFLQIAYG-LEELHSKNIVHRDIKNENFLCFQKDFYVLSDFS
. ... .      .| |.| .  .||.  .....                .. ..|..   ||  | |. |||..|.|||||  | |        |.|| 
CYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFG

VSTILDD----------------PDQKLEDTKGSPAFLSPEECSGEAFYPK------PADVWAYGVSLYLAVYKKLPFNLDQSN--ACPVANT------V
|...|.|                 .||     |.| . .||  ...    .       .|.|  |  .   .  | |.   .      . ..       .
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQF

LLVTQNLETQTLQFPE-----------------NADVDSFVEDLISQCLNKDPTQRPTFTEITK--HTYF
 .. . .. .  ..|.                    . .   | |..||.||| .||| ..  |  |  .
EQL-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 94534.m00165.AA CAMKK-Unclassified 159-255 25 6e-28 87.89 In-house 184-334 (392) Show / Hide 
Range on Protein: 159-255
Range on HMM: 184-334/392
Sequence Identity: 25% (39 aa)

FLQIAYGLEELHSKN---------------------IVHRDIKNENFLCFQKDF-----YVLSDFSVSTILDDPDQK-LEDTKGSPAFLSPEECSGEAFY
|.|.. ||  .| .|                     |.||||| .| |. . |       ...||..|.|. . .|| | .. | ..|..|| .| | | 
FRQCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEFWSKENFK

PKPAD---------------------------VWAYGVSLYLAVYKKLPFN
 .. |                           .|. ||..|  ||..|||.
YDYNDYSFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPFW
Kinase 94534.m00165.AA TyrKc 48-319 22 7.1e-14 1.7 SMART 1-280 (280) Show / Hide 
Range on Protein: 48-319
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

YVFLREIGSGAMSHVYEAVHTETGEHIAAKVYNLIQLCKPTLRSEPPPIDDVQKEIKIMMSI--DHSYILSLIEAIEDDAT-----RSLIIFMPFAQYGS
 ......|.||   ||... .   .  | |. .               . |  .|..||...  .|  |. |. .. ..         | | | .. .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD

VQTLLDKNQ--MNQDEISICFLQIAYGLEELHSKNIVHRDIKNENFLCFQKDFYVLSDFSVSTILDDP-------DQKLE----DTKG-SPAFLSPEECS
 .  | |..   . ..     .||| | | |||||..|||.   | |   .     |||  |  ..|        | .      ..|.  |    . || 
LKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

GEAFYPKPADVWAYGVSLY-LAVYKKLPFNLDQSNACPVANTVLLVTQNLETQ-TLQFPENA-------DVDSFVEDLISQCLNKDPTQRPTFTEITKHT
 .  .    |||..|| .. .  | . |   .  .      .   | .....   .  |.|.         |   . ...|| . || .||||.||  | 
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ----MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HE

YF
.|
CF
Kinase 94534.m00165.AA Pkinase_Tyr 48-179 23 2.3e-11 39.14 Pfam 1-137 (270) Show / Hide 
Range on Protein: 48-179
Range on HMM: 1-137/270
Sequence Identity: 23% (35 aa)

YVFLREIGSGAMSHVYEAVHT----ETGEHIAAKVYNLIQLCKPTLRSEPPP---IDDVQKEIKIMMSI-DHSYILSLIEAIEDDATRS--LIIFMPFAQ
 .|....|.||  .||... .    .|. . | |. .          .  ..   ..|  .|.|||... .|  |..|. ..  |  ..  ..| |....
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK---------EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT-DQGEPNQIYIVMEYMP

YGSVQTLLDKN-----QMNQDEISICFLQIAYGLEELHSKNIVHRDI
.|.  . | |.     . .  ..    .||| |.| |.|||..|||.
HGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 94534.m00165.AA CAMKK-Unclassified 294-319 34 2.5e-05 12.99 In-house 367-392 (392) Show / Hide 
Range on Protein: 294-319
Range on HMM: 367-392/392
Sequence Identity: 34% (9 aa)

DLISQCLNKDPTQRPTFTEITKHTYF
|||  ...|.|. | | . . .| .|
DLIQKMCDKNPKKRITIDQMLVHPWF
Kinase 94534.m00165.AA Pkinase_Tyr 292-319 46 3.9e-05 18.0 Pfam 245-270 (270) Show / Hide 
Range on Protein: 292-319
Range on HMM: 245-270/270
Sequence Identity: 46% (13 aa)

VEDLISQCLNKDPTQRPTFTEITKHTYF
. ||. || ..|| .||||.||  |  .
IYDLMKQCWHYDPEDRPTFSEI--HEQL
Kinase 94534.m00165.AA CAMKK-Unclassified 48-123 28 7.3e-05 11.43 In-house 1-89 (392) Show / Hide 
Range on Protein: 48-123
Range on HMM: 1-89/392
Sequence Identity: 28% (25 aa)

YVFLREIGSGAMSHVYEAVHTET-----GEHIAAKVYNLIQLCKPTLRSEPP--------PIDDVQKEIKIMMSIDHSYILSLIEAIED
|.|| ..|.|.   |  |. . |       . | ||.. ..| |  .              .. ||.|| ||  ..| .|  | | |.|
YEFLDKLGRGSFGKVKLATRRYTTDDGVQKQFAIKVFKKQKLKKKKFIYNDNAFTMKMKNRLHLVQQEIAIMKKLWHPNICKLYEVIDD