85686.m00166

Species: T.vaginalis
Alias: 85686.m00166, TvagK0182
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
85686.m00166.AA Protein None 339 None Fasta, JSON
85686.m00166.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 85686.m00166.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 85686.m00166.AA S_TKc 12-263 29 7.7e-73 249.22 SMART 1-231 (231) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-231/231
Sequence Identity: 29% (79 aa)

YVFKKAIGKGGFSTVYLVESEVYHQSYVAKVTPIDSEPIKEGDVDPLDAEIKALMSLSHQNIIRLYDHFTEGNNFYMILEYCQH--GSLQDSVGENG---
| . . ||||.|..||..     .. .  |. .           . .  ||. |..  | ||..|||.| . ...||..||| .  |.| |   ..|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LPLPQFITYGRQILSAPAFVHSKDIAHRDIKPGNILVDSLGHIKLSDFGISIRNANNVVSAFSGSFLYEAPEVILKKPHNPMQADIWSLGVLFAFL
    .|  .   | .||..| .. ||. | |||.|| |||.|.  |||..|||.. .      . | |.  | ||||.   ....  .|.||.|.... .
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

INGMTPWRSDNLTILKNRICTASYKLRSNTPPEVAELINKMIVIDPNERPTAQEILS-------MPLF
. | .|..  ..  . ..|.          .||. ..|.|. . ||..|||| |.|        .| |
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 85686.m00166.AA CAMKL 12-263 29 8.1e-67 212.21 In-house 1-297 (297) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-297/297
Sequence Identity: 29% (88 aa)

YVFKKAIGKGGFSTVYLVESEVY-HQSYVAKVTP---IDSEPIKEG---------DVDPLDAEIKALMSLS---HQNIIRLYDHFTEGNN------FYMI
| . | .|||.|..| | . . .  . .  |.     |  .|...          |.  .  ||. ...|.   |.|||.||....  ..      .|..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

LEYCQHGS--LQDSVGENG-----LPLPQFITYGRQILSAPAFVHSKDIAHRDIKPGNILVDSLG--HIKLSDFGIS-----I-RNANNVVSAFSGSFLY
.|||. |.  |.| . ..|     .| ..   | |||.|| .. ||..|.|||||| |||.|. |   ||..||| |     .  . ..  . | ||  |
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

EAPEVILK--KPHNPMQADIWSLGVLFAFLINGMTPWRSD--------NLTILKNRICTASYKLR--SNTPPEVAELINKMIVIDPNERPTAQEILSMPL
 |||....  ||..  ..||||.||.  ... |  |.. |        |   |...| .  |. .  .  . ..  || || . .|..|||...|.. | 
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

F
.
M

Kinase 85686.m00166.AA CAMK 17-263 19 3.4e-62 198.93 In-house 1-425 (425) Show / Hide
Range on Protein: 17-263
Range on HMM: 1-425/425
Sequence Identity: 19% (82 aa)

AIGKGGFSTVYLVESEVYH------------QSYVAKVTPIDSEPI------------------------KEGDVDPLDAEIKALMSLS-------HQNI
 .|.|.|..|.|..                 | . .|. . .  .                         .. | . .  ||. ...|.       | ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLYDHFTEGNN-------------------FYMIL---EYCQHG----SLQDSVGENG----------------LPLPQFITYGRQILSAPAFVHSKDI
|.||...  ...                   .||..   |||. |     | | . |.|                ..  .  .| |||.|| .. ||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDIKPGNILVDSL-----------------GHIKLSDFGIS--IRNA-----------------------NNVVSAFSGSFLYEA-PEVILK------
.|||.|| |||.|.                  . ||..||| .  ..                         .   . | |.  | | |||...      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------KPHNPMQADIWSLGVLFAFLINGMTPWRSD-------------NLTILKNRICTASYKLRSNTPP------------------------EVAE
       ||  . ..|.||.||.  ..  |  |...|             |.  |. .|... |   .   .                        |.  
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LINKMIVIDPNERPTAQEILSMPLF
||.|| . ||..|.|....|. | .
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 85686.m00166.AA Pkinase 12-263 28 5.8e-60 210.33 Pfam 1-293 (293) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-293/293
Sequence Identity: 28% (84 aa)

YVFKKAIGKGGFSTVYLVESEVYHQSYVAKVTPIDSEPIKEGD----VDPLDAEIKALMSLSHQNIIRLYDHFTEGNNFYMILEYCQHG----SLQDSVG
|.... ||.|.|..||.     . . .. |. . ..|  ..           .||. . .|.| ||.|||| |..... ||..|||..|    .| | . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL----SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

---ENGL--PLPQFITYGRQILSAPAFVHSKDIAHRDIKPGNILVDSLGHI----KLSDFGISIR--NANNVVSAFSGSFLYEAPEVILKKPHNPMQADI
   ....  .  . . | .|||.. .. ||. | |||.|| |||.|. |||    |..|||..    . ||. . | |.  | |||||.. .. .  .|.
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGVLFAFLINGMTPWRSD----NLTILKNRICTASY-KLRSNTP-----------------------PEVAELINKMIVIDPNERPTAQEILSMPLF
||.|.... ...| .|....    |    . .||   . .|... |                       .|  ..|....  ||..||||..||  | |
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 85686.m00166.AA Ciliate-E2-Unclassified 12-263 24 1.1e-59 204.55 In-house 1-352 (352) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-352/352
Sequence Identity: 24% (85 aa)

YVFKKAIGKGGFSTVYLVES----EVYHQSYVAKVTPIDSEPIKEGDVDPLDAEIKALMSLS-------------------HQNIIRLYDHFTEGNNFYM
| . | ||.|||..||...     ..|.. |  |.  ...  |.. | . .  |.|......                   | .|......|.  .|.|.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-E-IMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

ILEYCQHGSLQDSVGE------------------NGLPLPQFI-----TYGRQILSAPAFVHSKD-IAHRDIKPGNILVDSLG---HIKLSDFGISI---
..|||..|.|..   .                  . ..  | .     .| .|||..  . |.|  | |||||| |||.|. |   .||..|||||.   
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

--------------RNANNVVSAFSGSFLYE----APEVILKKPHNPM---QADIWSLGVLFAFLINGMTPWRSDNLTI----------------LKNRI
              .. ..  . |.|.  |     ||||. .. .. .   ..|||||||.. ... |  |  . | ..                |.. |
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

CTASYKLRS--------NTPPEVAELIN----KMIVIDPNERPTAQEILSMPLF
.   .. ..        . .||....||    ||.. .||.|.|...||  |.|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 85686.m00166.AA ULK 12-263 25 6e-58 198.83 In-house 1-329 (329) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-329/329
Sequence Identity: 25% (83 aa)

YVFKKAIGKGGFSTVYLVESEVYH----QSYVAKVTPIDSEPIKEGDVD------PLDAEIKALMSLS--------HQNIIRLYDHFTEG--NNFYMILE
|. .. .||| | .||  . .  .    . ...|. ..... .|. . .       |. ||| .  |         |.||..||| | .   ||.|.|.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCQHGSLQDSVGENG-----------LPLPQFITYGRQILSAPAFVHSKDIAHRDIKPGNILVDSL------------GHIKLSDFGISIRNANN-----
||..| |..   .|.           |. .. | . .|||..  . |.. | |||||| |||..              |..|..||| .    |.     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

VVSAFS------GSFLYEAPEVIL----KKPHNPMQADIWSLGVLFAFLINGMTP---W-RSDNLTILKNR----------ICTASYKLR-----SNTPP
.  ...      |. || ||...     .||..   .||||||..|  .. | .|   | ....| |...           |..   . .      .  |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

EVAELINKMIVIDPNERPTAQEILSMPLF
|. .|| .|...|...| . .|....|.|
ECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 85686.m00166.AA ULK 12-263 25 1.1e-57 197.91 In-house 1-324 (324) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-324/324
Sequence Identity: 25% (82 aa)

YVFKKAIGKGGFS-TVYLVESEVYH---QSYVAKVTPIDSEPIKEGDVD------PLDAEIKALMSLS---HQN--IIRLYDHFTEG--NNFYMILEYCQ
|. .. .||| |  .||  . .  .   | . .|. ....  .|. . .       |. ||. .  |    |.|  |..||| | .   ||.|.|.|||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

HGSLQDSVGENG----------LPLPQFITYGRQILSAPAFVHSKDIAHRDIKPGNILVDSL------------GHIKLSDFGISIR-NANNVVSAFS--
.| |..   .|.          |. .. | . .||...  . |.. | |||||| |||.               |..|..||| .   . ||        
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GSFLYEAPEVIL----KKPHNPMQADIWSLGVLFAFLINGMTPWRSDNLTILKNR--------------ICTASYKLR---SNTP--PEVAE
        |. || ||...     .||..   .||||||..|  .. | .|..|.  . ....              |..   . .   .. .  ||. .
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LINKMIVIDPNERPTAQEILSMPLF
|| .|...|...| . .||...|.|
LIRRMLQYDEKDRISWEEIFNHPWF

Kinase 85686.m00166.AA AGC 12-263 20 6.7e-57 144.59 In-house 1-395 (395) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-395/395
Sequence Identity: 20% (83 aa)

YVFKKAIGKGGFSTVYLVESE------VYHQSYVAKVTPIDS-EPIKEG-DVDPLDAE------------IKALMSLS----------HQNIIR-LYDHF
. |.| ||||.|..||||.           . |  ||   .    ||.  .|.   .|             . |. ..          |..|.. |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

TEGNN--FYMILEYCQ----------HGSLQDSV----GENGLPLPQFITYGRQ-------ILSAPAFVHS-KDIAHRD-IKPGNILVDSLGHIKLSDFG
   ..   |...||..           . |  .     .|  .. ..   |  .       |..|  . || ..| ||| .|| ||| |. |||||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

ISIRNAN----------------------------------------------------NVVSAFSG--SFLYEAPEVILKKPHNPMQADIWS--LGVLF
 . .. |                                                    .  . | |  .  | |||..    ...  .|.||  ||.|.
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKA-CDWWSFGLGCLM

AFLINGMTPWRSDNLT----------ILKNRIC------TASYKLR----------SNTPPEVAELINKMIVIDPNERPT----------AQEILSMPLF
  .. | .| ..||             . ..|.      .   |.           ..  ||   ||.|... ||..|..          |.|| . | |
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF





Kinase 85686.m00166.AA Ciliate-E2 12-263 22 2e-56 192.16 In-house 1-365 (365) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-365/365
Sequence Identity: 22% (85 aa)

YVFKKAIGKGGFSTVYLV-ESEVYHQS-----------------YVAKVTPIDSEPIKEGDVDPLDAEIKALM----------------SLSHQNIIRLY
| | | ||.|.|..||..   .| .|.                 . .|   . .  .|. ..  .  ||. ..                .|.| |||..|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKI--MKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

DHFT--EGNNFYMILEYCQHGSLQD--------------SVGENGLPLPQFITYGRQILS---------------APAFVHSKD-IAHRDIKPGNILVDS
..|     ||.|...||||.|.|.|              . . . . . . ... .|||.               |  . |||  | |||||| |||.  
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--

LGHIKLSDFGISIRNAN---------------------------------NVVSAFSGSFLYEAPEVILKKP--------HNPMQADIWSLGVLFAFLIN
   ||..|||.| .. .                                 |..  . |.  | |||.. .|.        .   ..|||||||.. ... 
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GMTPWRSDNLTILKNRICTASYK----------------LRSNTPPEVAELINK----MIVIDPNERPT-AQEILSMPLF
| .|.      . ..  |  ..                    . ..|.  ||.|    |.. ||..|.| ...||  | |
GKPPF------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 85686.m00166.AA STE 12-263 21 4.5e-49 169.35 In-house 1-359 (359) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-359/359
Sequence Identity: 21% (79 aa)

YVFKKAIGKGGFSTVYLV---------ESEVY------HQSYVAKVTPIDSEPIKEGD--------------VDPLDAEIKALMSLS--HQNIIRLYDHF
. . . ||||.| |||.          ..         .. .  |. .....  |. .              .. .  ||| .. ..  |.||.. |...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

TEG-------NNFYMILEYCQHGSLQDSVGENG---------------LPLPQFITYGRQILSA-PAFVHSKDIAHRDIKPGNILVDSLGHIKLSDFGIS
  .       .. ....||.  ||| | . ...               .| .| ... |||| .  .. ||. | ||||||.|||.     .||.|||..
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

IRNANN------------------VVSAFSGSFLYEAPEVILKKPHNPM------QADIWSLGVLFAFLINGMTPWRS-DNL----TILKNRICTA----
 . ...                      | |.  . |||||..  ..        ..|||||| .   ...|  ||    ..     |..| .. .    
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-------SYKLRSNTP-------------------PEVAELINKMIVIDPNERPTAQEILS--MPLF
       . .| ...                    ||  . |||  ..|||.||||.. |.   | .
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase 85686.m00166.AA MELK 12-263 32 1.3e-45 153.65 In-house 1-254 (254) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-254/254
Sequence Identity: 32% (83 aa)

YVFKKAIGKGGFSTVYLVESEVYHQSYVAKVTPIDSEPIKEGDVDPLDAEIKALMSLSHQNIIRLYDHFTEGNNFYMILEYCQHGSLQDS-VGENGLPLP
|   . || |||. | |    .  |    |.  .| . . . |.  . .|. || .|.||.| .||      . ..|..|||  | . |  . .. |   
YEVHDEIGTGGFAKVKLACHILTNQMVAIKI--MDKNQLGH-DLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEE

QFITYGRQILSAPAFVHSKDIAHRDIKPGNILVDSLGHIKLSDFGISIRNANNVVSA----FSGSFLYEAPEVILKKPHNPMQADIWSLGVLFAFLINGM
.   . |||.|| |.|||.  ||||.|| |.|.|   |.|| |||.  .   ..         ||  | |||.|  |      ||.||.|.|   |. |.
ETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGF

TPWRSDNLTILKNRICTASYKLRSNTPPEVAELINKMIVIDPNERPTAQEILSMPLF
 |.  ||. |.  .|    |.      ||  .|. .|. .||. |   ...|  |  
LPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV

Kinase 85686.m00166.AA MARK 117-263 40 5.8e-42 135.05 In-house 111-262 (262) Show / Hide
Range on Protein: 117-263
Range on HMM: 111-262/262
Sequence Identity: 40% (62 aa)

RQILSAPAFVHSKDIAHRDIKPGNILVDSLG--HIKLSDFGISIRNANNV-VSAFSGSFLYEAPEVILKKPHNPMQADIWSLGVLFAFLINGMTPWRSDN
|||.||  . |||.|.|||||| |||.|. |   ||..||| ||.  ..   . | |.  | |||..|||| .   .|||||||.  |.. |  |.. |.
RQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDT

--LTILKNRICTASYKLRSNTPPEVAELINKMIVIDPNERPTAQEILSMPLF
  .  |. .| . .|.  .. ..|   ||.......|.||||..||.. | .
QDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 85686.m00166.AA MARK 12-100 25 2.8e-16 49.89 In-house 1-91 (262) Show / Hide
Range on Protein: 12-100
Range on HMM: 1-91/262
Sequence Identity: 25% (24 aa)

YVFKKAIGKGGFSTVYLVESEVYHQSYVAKVTP---IDS-EPIKEGDVDPLDAEIKALMSLSHQNIIRLYDHFT--EGNN-FYMILEYCQHGSLQD
| ..| ||.|....|.|. .  ... .  |. .   ..  . .|     ..  ||. ...|.| |||.|.. .   . .. .|.|.||.  |.| |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMK-----NVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYD

Kinase 85686.m00166.AA TyrKc 12-263 21 2.2e-14 9.98 SMART 1-280 (280) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YVFKKAIGKGGFSTVYLVESEVYHQSYVAKVTPIDSEPIKEGDVDPLDAEIKALMSL--SHQNIIRLYDHFTEG-------NNFYMILEYCQHGSLQDSV
 ...| .| | | .||. .     .    |.   |.       .  .  |.. ...|  .|.||.|||   |..          ....||. ||.|.|  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

GENG--LPLPQFITYGRQILSAPAFVHSKDIAHRDIKPGNILVDSLGHIKLSDFGISIRNANN--------VVSA-F--SGSFL----YEAPEVILKKPH
 ...  |...... .  || .  .. ||| . |||.   |.||.. ...| |||| |    .         . ..    .| ..      |||.|     
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----

NPMQA------DIWSLGVL----FAFLINGMTPWRS-----DNLTILKNRICTASYKLRSNT---------PPEVAELINKMIVIDPNERPTAQEILSMP
  .        |.|| ||.    | .   |..|.        . . . ... .  .  .            |.|. ... .    ||..||| .||    
--NYGKFTTKSDVWSFGVCMWEIFTY---GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HE

LF
.|
CF

Kinase 85686.m00166.AA Pkinase_Tyr 61-157 31 3.7e-12 41.8 Pfam 53-158 (270) Show / Hide
Range on Protein: 61-157
Range on HMM: 53-158/270
Sequence Identity: 31% (33 aa)

EIKALMSL-SHQNIIRLYDHFT-EGNN--FYMILEYCQHGSLQDSVGEN-----GLPLPQFITYGRQILSAPAFVHSKDIAHRDIKPGNILVDSLGHIKL
|.| ...| .|.||.|||   | .|     |...||..||.| |   ..      |.... . . .|| .. .. .|| . |||.   |.||.. ...| 
EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKI

SDFGIS
.||| .
CDFGLA