Gene 85241.m00273 (T.vaginalis)

85241.m00273

Species: T.vaginalis
Alias: 85241.m00273, TvagK0044
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
85241.m00273.AA Protein None 360 None Fasta, JSON
85241.m00273.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of 85241.m00273.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85241.m00273.AA CAMKL 8-256 36 2.6e-101 324.08 In-house 1-297 (297) Show / Hide 
Range on Protein: 8-256
Range on HMM: 1-297/297
Sequence Identity: 36% (109 aa)

YVFDKHLSSGNFGKVYVATH-EPSNEKVAIKIVT--KNA-HSINSSK--------------EYDIMMKLH---HLFIVSLYEVIEDAEN------LYLVM
| . | |  |.||||  |||    .|||||||.   |     .....              |. ||..|.   |  |..||||||. |.      .||||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYVEGPT--LLDYIKEQ----GKLPDWKIKHIFCEILSAVLYLHKTLKIVHRDLKLENIIIDKNL--NVRLLDFGLSNQQK-H---DAALFKTTCGSPSY
||..|    |.|||...    |..| .  ...|. |.||| |.|.   |||||.|.||| .|.|   |. . |||.||... .   .  ..|| ||||.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

SAPELLMG--KPYN-HKVDMWSLGIILYALTYNTLPFGDPNM-------QSLTSKIITKDPFYPMIS---NQQIITVIKELLNKDPEERPSSEEAAELPW
 |||.. |  |||.  |||.||.|.||||. . .||| |...       . .  ..| .. .|| |      . .  |. .|...||.||. ..  . ||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

I
 
M
Kinase 85241.m00273.AA CAMK 13-256 24 1.8e-92 298.21 In-house 1-425 (425) Show / Hide 
Range on Protein: 13-256
Range on HMM: 1-425/425
Sequence Identity: 24% (104 aa)

HLSSGNFGKVYVATHEPSN------------EKVAIKIVTKNAHS------------------------------INSSKEYDIMMK-------LHHLFI
 | .|.||||. ..|  ..            .||||||. |. ..                               |  .|..||.|       |.|  |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSLYEVIEDAEN-------------------LYLVM---EYVEGP----TLLDYIKEQ---------------GKLPDWKIKHIFCEILSAVLYLHKTLK
..||||.||...                   .|.||   ||..|      |.|||.|.               |... .  ...|  |.||| |.|.   
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-

IVHRDLKLENIIIDKN-----------------LNVRLLDFGLSNQQKH-----------------------DAALFKTTCGSPSYSA-PELLMG-----
|||||||.||| .|.|                  |. . |||..|. ..                       .  ..|| ||.|.| | ||.| |     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------KPYNHKVDMWSLGIILYALTYNTLPFGDP-------------NMQSLTSKIITKD-PFYPM----------------ISNQ-------QII
         ..|. |.||||.|.|||..   ..|| ..             |.. |  ||.. .  |.|                 ||..       . .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

TVIKELLNKDPEERPSSEEAAELPWI
  |. .|..|||.|.. |.. . ||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 85241.m00273.AA S_TKc 8-256 34 2.5e-87 297.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-256
Range on HMM: 1-231/231
Sequence Identity: 34% (91 aa)

YVFDKHLSSGNFGKVYVATHEPSNEKVAIKIVTKNAHSINSSKEYDIMMKLHHLFIVSLYEVIEDAENLYLVMEYVEG--PTLLDYIKEQGK------LP
| . ... .| ||||| ..|  ....|||||.      ..  .| .|..| || .|| ||.|..| ..||.||||..|   .|.||||..|.      .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

DWKIKHIFCEILSAVLYLHKTLKIVHRDLKLENIIIDKNLNVRLLDFGLSNQQKHDAALFKTTCGSPSYSAPELLMGKPYNH-KVDMWSLGIILYALTYN
   .......|..|. |.|.  .|.||||| ||| .|.  .. . ||||. |        .| ||.| | |||.|   .|.. |.|.||.|.||| . . 
E-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

TLPFGDPNMQSLTSKIITKDPFYPMISNQQIITVIKELLNKDPEERPSSEEAAE-------LPWI
  ||     . .. |.|           .. .  |. .|.||||.||.  || .        ||.
YPPFP---QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 85241.m00273.AA MARK 8-256 39 1.9e-86 282.59 In-house 1-262 (262) Show / Hide 
Range on Protein: 8-256
Range on HMM: 1-262/262
Sequence Identity: 39% (103 aa)

YVFDKHLSSGNFGKVYVATHEPSNEKVAIKIVT---KNA-HS-INSSKEYDIMMKLHHLFIVSLYEVIE--DAEN-LYLVMEYVEGPTLLDYIKEQ--GK
| . | .  |...||..|.| ....||||||.    .|  ..  |   | .||.||.|  |..|..|||  . .. .||.|||..|  |.||||..  |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LPDWKIKHIFCEILSAVLYLHKTLKIVHRDLKLENIIIDKNL--NVRLLDFGLSNQQKHDAALFKTTCGSPSYSAPELLMGKPYN-HKVDMWSLGIILYA
|.    ..||  |.||| |.|.   |||||.|.||| ||.|   |. . |||.|.. . .  | .| ||.|.| |||.. .|||.  |||.||||..||.
LHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKL-NTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYF

LTYNTLPFGDPN--MQSLTSKIITKDPFYPMISNQQIITVIKELLNKDPEERPSSEEAAELPWI
..  ..|| . .  .  |  || . .. .|.    ..   |. ||. .|||||. ||  . ||.
MVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 85241.m00273.AA AMPK 8-256 40 1.3e-85 254.16 In-house 1-254 (254) Show / Hide 
Range on Protein: 8-256
Range on HMM: 1-254/254
Sequence Identity: 40% (103 aa)

YVFDKHLSSGNFGKVYVATHEPSNEKVAIKI-----VTKNAHSINSSKEYDIMMKLHHLFIVSLYEVI-EDAENLYLVMEYVEGPTLLDYIKEQGKLPDW
|. .| .  | |||| ..||.  .|||||||      .. . .   ..| .|. .. |  |. ||||| |  . ...||||| |  | |||   |.|.  
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

KIKHIFCEILSAVLYLHKTLKIVHRDLKLENIIIDKNLNVRLLDFGLSNQQKHDAALFKTTCGSPSYSAPELLMGKPYN-HKVDMWSLGIILYALTYNTL
  .  |  |.|.| |.|. ..|||||||.||. .|.| |. . ||||||  | |. . || |||| | |||.  ||.|.  .|| || |.||||.   .|
EACRFFQQIISGVEYCHR-HMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMK-DGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYL

PFGDPNMQSLTSKIITKDPFYPMISNQQIITVIKELLNKDPEERPSSEEAAELPWI
|| |.|  .|  ||.  ..  |   ....   ||..|..||..| . ..  . || 
PFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 85241.m00273.AA NuaK 8-256 38 9.2e-84 219.98 In-house 1-252 (252) Show / Hide 
Range on Protein: 8-256
Range on HMM: 1-252/252
Sequence Identity: 38% (99 aa)

YVFDKHLSSGNFGKVYVATHEPSNEKVAIKIVTKNAHSINSS-------KEYDIMMKLHHLFIVSLYEVIEDAENLYLVMEYVEGPTLLDYIKEQGKLPD
| | | | .| .|||  || . .  .|||| . |..  | .        .|  ||  |.|  |.. ||| |  . . .||||  |  | ||| | ..|| 
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCK--IEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPE

WKIKHIFCEILSAVLYLHKTLKIVHRDLKLENIIIDKNLNVRLLDFGLSNQQKHDAALFKTTCGSPSYSAPELLMGKPYN-HKVDMWSLGIILYALTYNT
  ..|.|  | |||.| ||  .|.|||||||||  |.| |..  ||||||   ||  . .| |||| |  ||   |.||.   || ||||..||.. | |
REARHFFRQIVSAVHYCHKH-RICHRDLKLENILLDQNCNAKIADFGLSNYY-HDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGT

LPFGDPNMQSLTSKIITKDPFYPMISNQQIITVIKELLNKDPEERPSSEEAAELPWI
.||.  . . |   |   . . |    ..  . | ..|  .|. | . .. .. .|.
MPFDGHDFKHLVKQISQGAYYEPCKPSDA-CMLIRWMLMVNPRRRATIYDICHHWWV
Kinase 85241.m00273.AA AGC 8-256 21 4.1e-81 208.66 In-house 1-395 (395) Show / Hide 
Range on Protein: 8-256
Range on HMM: 1-395/395
Sequence Identity: 21% (86 aa)

YVFDKHLSSGNFGKVYVATHE------PSNEKVAIKIVTKNA--------HSINSSKE------------YDIMMKLH----------HLFIVS-LYEVI
. | |... | ||||| . .        ...  |.|.. |             .   |             .|..|..          | |||. |.   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EDAEN--LYLVMEYVE----------GPTLLDYIK---EQGKLPDWKIKHIFCE-------ILSAVLYLHKTLKIVHRD-LKLENIIIDKNLNVRLLDFG
.| ..  ||.||||..          |  |. ...    .|...   ......|       |..|. |||. ..|.||| ||.||| .|.. ...| |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSNQ--------------------------------------QKHDA------------ALFKTTCG--SPSYSAPELLMGKPYNHKVDMWS--LGIILY
|. .                                       ....            .. .| ||  .| | ||| |    |.. .| ||  ||...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ALTYNTLPFGDPNMQ----------SLTSKII------TKDPFYP----------MISNQQIITVIKELLNKDPEERPS----------SEEAAELPWI
 . .   || . | |           .  ||.      .... .|              ..    || ||.||||.|.            ||  . || 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 85241.m00273.AA Pkinase 8-256 31 6e-78 270.06 Pfam 1-293 (293) Show / Hide 
Range on Protein: 8-256
Range on HMM: 1-293/293
Sequence Identity: 31% (95 aa)

YVFDKHLSSGNFGKVYVATHEPSNEKVAIKIVTKNAHSINSSK--------EYDIMMKLHHLFIVSLYEVIEDAENLYLVMEYVEGP----TLLDYIK--
|.. . . ||.||.|| ..|  ....||.||. |   ...|.|        |  || .|.| .|| ||.. ||  ..|.||||.||      | |||.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

EQGKL--PDWKIKHIFCEILSAVLYLHKTLKIVHRDLKLENIIIDKNLNV----RLLDFGLSNQ--QKHDAALFKTTCGSPSYSAPELLM-GKPYNHKVD
..|..  ..| .|... .||... |.|.  .|.|||||.||| ||.| ..    .. ||||. |    ..   ..| ||.| | |||... |..| .|||
RHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVD

MWSLGIILYALTYNTLPFGDP------NMQSLTSKIITKDPFYPMISN---------------------QQIITVIKELLNKDPEERPSSEEAAELPWI
|||.|.||| .    .|| .       ... .  .|  ... ..                         .  . .|| .|.|||..||. |.. . ||.
MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 85241.m00273.AA Ciliate-E2-Unclassified 8-256 25 3.9e-76 259.24 In-house 1-352 (352) Show / Hide 
Range on Protein: 8-256
Range on HMM: 1-352/352
Sequence Identity: 25% (88 aa)

YVFDKHLSSGNFGKVYVATHEPSNEKVAIKIVTKNAHSINSSKEY--------DIMMKLH-------------------HLFIVSLYEVIEDAENLYLVM
| . | . .|.||||| . |.  ... |.|.  |. .    ....        ..|...                    |.||| .... .| .|.|.||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYVEGPTLLDYIKEQGK-----------------LPDWKIK-----HIFCEILSAVLYLHKTLKIVHRDLKLENIIIDKNL---NVRLLDFGLSNQQKHD
||.|| .|..|||...|                 ... ..|     ..| .||..  |||. ..|.|||.|.|||..|.|    .... |||.| ... .
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---------------AALFKTTCGSPSYS----APELLMGKPYN----HKVDMWSLGIILYALTYNTLPFGDPNMQS----------------LTSKIIT
                 ...|.||.|.|     |||.|.|. |.    .|.|.||||.|||.. ....||.|.|  .                | ..|. 
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

KDPFYP--------MISNQQIITVIK----ELLNKDPEERPSSEEAAELPWI
|....|        ...... .  |.     .|.|.|..|.. |.. . ||.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 85241.m00273.AA Ciliate-E2 8-256 24 2.3e-70 240.05 In-house 1-365 (365) Show / Hide 
Range on Protein: 8-256
Range on HMM: 1-365/365
Sequence Identity: 24% (94 aa)

YVFDKHLSSGNFGKVYVATH-----------------------EPSNEKVAIKIVTKNAHSINSSKEYDI---------------MMKLHHLFIVSLYEV
| | | . .||||.|| ...                       .  . ..|.||. ||   . ..... .               . .| | .|. .||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IE--DAENLYLVMEYVEGPTLLDYIKEQ-----------GKLPDWKIKHIFCEILS---------------AVLYLHKTLKIVHRDLKLENIIIDKNLNV
 .  | .|.||||||..| .|.||||..           ... . .||.|. .||.               |. |||.  .|.|||.|.|||..     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RLLDFGLSNQQKHD-------------------------------AALFKTTCGSPSYSAPELLMGKP---------YNHKVDMWSLGIILYALTYNTLP
 . ||||| ... |                                 .|.|.||.| | ||| |.||.         |..|.|.||||.||| . .. .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FGDPNMQSLTSKIITK-DPFYPMISNQ------------------QIITVIKE----LLNKDPEERPS-SEEAAELPWI
|          ..| . .  .|   .|                  . .  ||     .|.||||.|..  |.. . ||.
F---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 85241.m00273.AA QIK 8-256 35 7.2e-62 211.85 In-house 1-272 (272) Show / Hide 
Range on Protein: 8-256
Range on HMM: 1-272/272
Sequence Identity: 35% (96 aa)

YVFDKHLSSGNFGKVYVATHEPSNEKVAIKIVTKNA-HSINSSK---EYDIMMKLHHLFIVSLYEVIEDAENLYLVMEYVEGPTLLDYIKEQGK------
|  .. .  |||. | .|.|    .||||||. | .  . |  |   |  ||  | | .|. ||.|.|  . .|.|.|| ..  . ||. ..|.      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------LPDWKIKHIFCEILSAVLYLHKTLKIVHRDLKLENIIIDKNLNVRLLDFGLSNQQKHDAALFKTTCGSPSYSAPELLMGKPYN-HK
              ..  . . .| .|.||| |.|| ..||||||| ||| .|.|.|. . |||.|| .| .. | .| |||| | |||.. || |.  |
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHK-RNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLL-MTWCGSPPYAAPEMFEGKEYDGPK

VDMWSLGIILYALTYNTLPFGDPNMQSLTSKIITKDPFYPMISNQQIITVIKELLNKDPEERPSSEEAAELPWI
|| ||.|..||.|    |||  ...|.| ....      |    |   . |.  |  ||| | . .   . .|.
VDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 85241.m00273.AA ULK 8-256 26 2.9e-59 203.19 In-house 1-324 (324) Show / Hide 
Range on Protein: 8-256
Range on HMM: 1-324/324
Sequence Identity: 26% (86 aa)

YVFDKHLSSGNFG-KVYVATHEPS---NEKVAIKIVTKNAHSINSS------------KEYDIMMKLH------HLFIVSLYEVIEDA--ENLYLVMEYV
|. .. | .| || ||| .... .   |..||.|.. |.  .....            .|  || ||.      |  || ||.. |..   |.|..||| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC

EGPTLLDYIKEQGKLPDWK----------IKHIFCEILSAVLYLHKTLKIVHRDLKLENIIIDKNLN------------VRLLDFGLSNQ-QK--HDAAL
.| .| .|||...|||  .          ....|  |...  .|||  .|.|||.|..|| | ..              . . |||.. . ..   .. .
NGGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHK-HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQM

FKTTC------GSPSYSAPELLM----GKPYN-HKVDMWSLGIILYALTYNTLPFGDPNMQSLT-------------SKIITKDPF-YPM-----ISNQQ
..|..      |.| | ||..|.    .|||. .|.|.||||.|.| . |.  ||  .  ...                .| . |. .|.     .  ..
CQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPE

IITVIKELLNKDPEERPSSEEAAELPWI
..  |. .| .|...| | ||  . ||.
CKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 85241.m00273.AA Pkinase_Tyr 8-193 27 1.3e-19 67.05 Pfam 1-205 (270) Show / Hide 
Range on Protein: 8-193
Range on HMM: 1-205/270
Sequence Identity: 27% (58 aa)

YVFDKHLSSGNFGKVYVATHE----PSNEKVAIKIVTKNAHSINS------SKEYDIMMKL-HHLFIVSLYEVIE-DAEN--LYLVMEYVEGPTLLDYIK
 .|.| | .|.||.|| .|        . .||.|.. |. ..          .|  ||..| ||  ||.|| |.  . |   .|.||||...  |||| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

E----QGKLPDWKIKHIFCEILSAVLYLHKTLKIVHRDLKLENIIIDKNLNVRLLDFGLSNQQ-KHDAALFKTTC---GSPSYSAPELLMGKPYNHKVDM
.    ...|.   . ..  .| ..  ||.   ...||||   |. ...|. |.  ||||.    . |   ....          ||| .. . ...| | 
KHREDKQPLTMKDLLQMCWQIAKGMEYLES-KNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDV

WSLGIILY
|| |. ..
WSFGVLMW
Kinase 85241.m00273.AA TyrKc 8-254 26 3.2e-17 55.68 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-254
Range on HMM: 1-280/280
Sequence Identity: 26% (76 aa)

YVFDKHLSSGNFGKVYVATHEPSNEKVAIKIVTKNAHSINSSKEYDIMMKL--HHLFIVSLYEVIEDA-------ENLYLVMEYVEGPTLLDYIKEQGKL
 ...| | .|.||.|| .|     ..||.| . ..|      .|  ||.||  ||  || || |. .        | |..||||...  |.||... .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

PDWKIKHIFC-EILSAVLYLHKTLKIVHRDLKLENIIIDKNLNVRLLDFGLSNQQKHD------AALFKTTC--GSPS-----YSAPELLMGKPYNHKVD
  .| .. ||  | .   |||.  ...||||   |. ...|. |.  |||||   ..|          ...   |. .       ||| .. . ...| |
LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

MWSLGIILY-ALTYNTLPFGD-----PNMQSLTSKIITK--DPFYPM-------ISNQQIITVIKELLNKDPEERPSSEEAAELP
 || |. ..  .||   |  .      . | .  .. .    |  |        .  . . ...|.  . |||.||. .|  |. 
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF