Gene 84692.m00144 (T.vaginalis)

84692.m00144

Species: T.vaginalis
Alias: 84692.m00144, TvagK0460
External Links:
Annotation:

Classification

Group: CK1
Family: TTBK

Sequence

Name Sequence Type Origin Length Description Download
84692.m00144.AA Protein None 350 None Fasta, JSON
84692.m00144.kin_dom Protein Kinase Domain None 188 None Fasta, JSON

Protein domain

Protein domains of 84692.m00144.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84692.m00144.AA CK1 10-264 28 1.3e-90 307.33 In-house 1-339 (339) Show / Hide 
Range on Protein: 10-264
Range on HMM: 1-339/339
Sequence Identity: 28% (97 aa)

YTVGPKIGAGAFG-EIYAV-----RNAGDN-----KIFALKVEPL-SNRRNILELEASVLKRL---------------------SPCPYFPKFRIFGRTS
..|. ||| |.|| .|| |     ..  .|     . .|.||||  |. .. ...|.......                     ..||..... . |.. 
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

TYS-WLVMELLGPSLSTVVK--RLPSGRLSMSTGLRVANSILCGLESMHKKGFIHRDVKPSNILLRR-------------SREYP-IAIIDFGLSR-VYV
 |  ..||.||||.|. . |  |.. ...||.|.|..|  .| .|| || .||||||.||.|... |             ..|.  . .||||..|  |.
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR

DR-----------KTERHLPARA---HPGFRG-TAVYASPNAHMHQDLSRRDDLISWFYLVIDVMAGP--LPWKKLENRAE-----ILHMKRRISISNLS
|.           || .| |.|    . |||| || |.|.|.| .....||||| ||||..|. . |   |||....   .     . .||. .   .. 
DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM

DQ------------IAHQLTLIWDHIQSLGFTDAPNYAYM
 .            .  ..  |...| || . |.|.|.. 
STPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase 84692.m00144.AA TTBKL 10-268 30 9.1e-80 268.97 In-house 1-288 (288) Show / Hide 
Range on Protein: 10-268
Range on HMM: 1-288/288
Sequence Identity: 30% (89 aa)

YTVGPKIGAGAFGEIYAVRNAGDNKI-FALKVEPLS-NR-RNILELEASVLKRLS--PCPYFPKFRIFGRTSTYSWLVMELLGPSLSTVVKRLPSGR-LS
...  .|| |.||..| |.. .| |  .|.|.|. . ..  .....|. ||..|.  ..|.|||.   |..  |...||.|.||.|. . |..| .. .|
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

MSTGLRVANSILCGLESMHKKGFIHRDVKPSNILLRRS---REY--PIAIIDFGLSRVYV----------DRKTERHLPARA---HPGFRGTAVYASPNA
 .| .|..  .| .|  || .|||||||||.|. .  .   .|.   . .||||..| |.           ... .. ..|    ...||||  |.|||.
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM

HMHQDLSRRDDLISWFYLVIDVMAGPLPWKKLENRAEILHMKRRISISNLSDQ------IAHQLTLIWDHIQSLGFTDAPNYAYMHDLL
|......| ||| ||.| .|  ..| |||. .|.. || |||.  .  .|.        .  ... .  |. || . | |.| ..  ..
HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase 84692.m00144.AA Worm6 10-264 31 4.7e-70 239.05 In-house 1-279 (279) Show / Hide 
Range on Protein: 10-264
Range on HMM: 1-279/279
Sequence Identity: 31% (88 aa)

YTVGPKIGAGAFGEIYAVRNAGDNK--IFALKVEP--LSNRRNILELEASVLKRL--SPCPYFPKFRIFGRTST--YSWLVMELLGPSLSTVVKRLPSGR
..|. ||| |.|| .| | .. |.|   ||.|.|    .. |. | .|..|||..  ..|..|.|.   |..    . ..||.|.|..|.   | .| ..
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

LSMSTGLRVANSILCGLESMHKKGFIHRDVKPSNILLRR------SREYPIAIIDFGLSR--VYVDRKTERHLPAR-AHPGFRGTAVYASPNAHMHQDLS
.||.|||..|   | ..| .|. |||||||||.|    |        .  | ..|||..|  .| ....|.. | | .. |||||  ||. ..| .|...
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTP-RWTACGFRGTVRYAPLACHKGQEQC

RRDDLISWFYLVIDVMAGPLPWKKLENRAEIL--HMKRRISI-----SNLSDQIAH-QLTLIWDHIQSLGFTDAPNYAYM
|.||. ||||....   | |||.... . .    ....|  .     . .   . . ... | | | .. . |.|.|.. 
RKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase 84692.m00144.AA TTBK 10-264 36 8.5e-69 234.87 In-house 1-257 (257) Show / Hide 
Range on Protein: 10-264
Range on HMM: 1-257/257
Sequence Identity: 36% (95 aa)

YTVGPKIGAGAFGEIYAVRNAGDN-KIFALKVEPLSNRRNILELEASVLKRLSPCPYFPKFRIFGRTSTYSWLVMELLGPSLSTVVKRLPSGRLSMSTGL
 .|  ||| |.|||||   .   .    |.|||     . .| .|  |||.|  |..  .|   ||   . ..||.|.| .|.      | |  |.|| |
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTL

RVANSILCGLESMHKKGFIHRDVKPSNILL-RRSREYPIA-IIDFGLSRVYVDRKTERHLPARAHPGFRGTAVYASPNAHMHQDLSRRDDLISWFYLVID
|.   || ..|| |  || |||.||||  . | . .. .  ..|||| | |.  . |   |.|.  |||||. ||| |||  ... |.||| | ||. . 
RLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVR-PPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVE

VMAGPLPWKKLENRAEILHMKRRISISNLSDQIAHQLTLIWDHIQSLGFTDAPNYAYM
 . | ||| |.  . .. .|| .     | . . |.. .  |||.||.. | |.|. .
FVQGQLPWRKIKDKDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase 84692.m00144.AA CK1 10-262 32 2.1e-51 175.2 In-house 1-271 (271) Show / Hide 
Range on Protein: 10-262
Range on HMM: 1-271/271
Sequence Identity: 32% (90 aa)

YTVGPKIGAGAFGEIYAVRNAGDNKIF---ALKVEPLSNRRNILELEASVLKRLSP------CPYFPKFRIFGRT--STYSWLVMELLGPSLSTVVKRLP
| || |||.|.||.|| . |  .|. .   | |.|.  ..   |  || ..|.|        |...|. . .|.   . |  .||.||||||    . . 
YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLED-LFNFC

SGRLSMSTGLRVANSILCGLESMHKKGFIHRDVKPSNILLRR--SREYPIAIIDFGLSRVYVDRKTERHLPARAHPGFRGTAVYASPNAHMHQDLSRRDD
....|. | | .|  ... .| .|.|.|||||.|| |.|  |   ..  . ||||||.  |.| || .| | | . .. ||| ||| |.|.    |||||
NRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDD

LISWFYLVIDVMAGPLPWK--KLENRAE----ILHMKRRISISNLSDQ-IAHQLTLIWDHIQSLGFTDAPNYA
. |  |  .    | |||   | ... .    |. .|. ...  |    .  ...    .. .|.| ..|.|.
MESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase 84692.m00144.AA CK1-Unclassified 10-197 38 3e-51 149.52 In-house 1-199 (244) Show / Hide 
Range on Protein: 10-197
Range on HMM: 1-199/244
Sequence Identity: 38% (77 aa)

YTVGPKIGAGAFGEIYAVRNAGDNKIFALKVEPLSNRRNILELEASVLKRLSPCP-------YFPKFRIFGRT--STYSWLVMELLGPSLSTVVKRLPSG
| |. |||.|.||||| . |  .|. .|.|.|   ..   |  || ....|  .        ..||   .|.   ..|  .||.||||||    .    .
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMC-NR

RLSMSTGLRVANSILCGLESMHKKGFIHRDVKPSNILL--RRSREYPIAIIDFGLSRVYVDR-KTERHLPARAHPGFRGTAVYASPNAHMHQDLSRRDDL
..|. | |  |. ..  .| .|.|.||||| || |.|   .  . . . |||||||  |.|. || .| | |   .. ||| ||| |||     ||||||
KFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDL
Kinase 84692.m00144.AA CK1-A 10-264 34 7.3e-51 175.29 In-house 1-261 (261) Show / Hide 
Range on Protein: 10-264
Range on HMM: 1-261/261
Sequence Identity: 34% (90 aa)

YTVGPKIGAGAFGEIYAVRNAGDNKIFALKVEPLSNRRNILELEASVLKRLSPCPYFPKFRIFGRTSTYSWLVMELLGPSLSTVVKRLPSGRLSMSTGLR
| .  |||.|.||.||   |  . .  |.|.|    |   |  || | . |. |. .|. | .|.   |  .||.||||||  .   . . | .| | | 
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFN-FCKRRFTMKTVLM

VANSILCGLESMHKKGFIHRDVKPSNILLRRSRE-YPIAIIDFGLSRVYVDRKTERHLPARAHPGFRGTAVYASPNAHMHQDLSRRDDLISWFYLVIDVM
.|  ..  .| .|.|.|||||.|| | |.   |    . .|||||.. | | .|..|.| |      ||| ||| |||.  . |||||. |  | ..   
LADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFN

AGPLPWKKLENRAE------ILHMKRRISISNLSDQIAHQLTLIWDHIQSLGFTDAPNYAYM
 | |||. ..  .       |.  |  ..|  |      .....  ....|.| ..|.| |.
RGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase 84692.m00144.AA CK1-D 10-264 34 4.7e-48 165.96 In-house 1-261 (261) Show / Hide 
Range on Protein: 10-264
Range on HMM: 1-261/261
Sequence Identity: 34% (90 aa)

YTVGPKIGAGAFGEIYAVRNAGDNKIFALKVEPLSNRRNILELEASVLKRLSPCPYFPKFRIFGRTSTYSWLVMELLGPSLSTVVKRLPSGRLSMSTGLR
| .| |||.|.||.||   |   |   |.|.|..  .   |..|. . | ..     |. | .|.   |  .||.||||||  .     . . |. | | 
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFN-YCHRKFSLKTVLM

VANSILCGLESMHKKGFIHRDVKPSNILLR-RSREYPIAIIDFGLSRVYVDRKTERHLPARAHPGFRGTAVYASPNAHMHQDLSRRDDLISWFYLVIDVM
.|. ..| .| .| . |||||.|| | |.    |   . ||||||.. | | .|..|.| | .    ||| ||| | |.  . |||||| |  |...   
LADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFN

AGPLPWK------KLENRAEILHMKRRISISNLSDQIAHQLTLIWDHIQSLGFTDAPNYAYM
 | |||.      | .    |   |  ..|  | .   .. .   .. ..| | | |.|.|.
RGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase 84692.m00144.AA CK1-G 10-264 34 2.6e-42 141.17 In-house 1-266 (266) Show / Hide 
Range on Protein: 10-264
Range on HMM: 1-266/266
Sequence Identity: 34% (92 aa)

YTVGPKIGAGAFGEIYAVRNAGDNKIFALKVEPLSNRRNILELEASVLKRLSPCP-YFPKFRIFGRTSTYSWLVMELLGPSLSTVVKRLPSGRLSMSTGL
| ||.||| | |||..  .|   |   | | ||   |   | .|    | |. ||   |.   ||    |  .||.||||||      .   . |. | .
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFD-WCDRKFSVKTVC

RVANSILCGLESMHKKGFIHRDVKPSNILLRRS---REYPIAIIDFGLSRVYVDRKTERHLPARAHPGFRGTAVYASPNAHMHQDLSRRDDLISWFYLVI
 ||  ..  .| .|..  | ||||| | |  |.   ..  | |||||. . |.| .|..| | | |    ||| | | | |. .  |||||. .   . .
MVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFM

DVMAGPLPWKKL------ENRAEILHMKRRISISNLSDQ--IAHQLTLIWDHIQSLGFTDAPNYAYM
  . | |||  |      |    |   ||.. |  | .   . .|.      . .| | . | | |.
YFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase 84692.m00144.AA Pkinase 10-196 25 8.1e-36 127.73 Pfam 1-194 (293) Show / Hide 
Range on Protein: 10-196
Range on HMM: 1-194/293
Sequence Identity: 25% (53 aa)

YTVGPKIGAGAFGEIYAVRNAGDNKIFALKVEPLSNRRNILEL-------EASVLKRLSPCPYFPKFRIFGRTSTYSWLVMELLGP-----SLSTVVKRL
|..| |||.|.||. |  .. |..||.|.|. ... ...  ..       |....|||  .|.  ... . ..... ..|||...      .|...... 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

PSGRL--SMSTGLRVANSILCGLESMHKKGFIHRDVKPSNILLRRSREYP---IAIIDFGLSRVYVDRKTERHLPARAHPGFRGTAVYASPNAHM-HQDL
 .|..  |. .  ...  ||.||| .|..|.||||.||.|||.  .. ..   . |.||||....       . . .   .| ||  |..|  .. .|. 
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRGGQYY

SRRDD
... |
GPKVD
Kinase 84692.m00144.AA CK1-Unique 10-215 22 1.2e-25 85.88 In-house 1-233 (337) Show / Hide 
Range on Protein: 10-215
Range on HMM: 1-233/337
Sequence Identity: 22% (53 aa)

YTVGPKIGAGAFGEIYAVRNAGDN------KIFALKVEPLSNRRN--ILELEASVLKRLSPCP-------YFPKFRIFGRTSTYSWLVMELLGPSLSTVV
. |  .||.| .|  . |    .       . .. | |  . ..   .|  | .|.| .. |         |.. . |. .  ..|.|| ..|||.   .
WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFHQHRDWWWIVMTMHGPSMEE-C

KRLPSG-RLSMS------TGLRVANSILCGLESMHKKGFIHRDVKPSNILLRRSR---EYPIAIIDFGLS-RVYVDRKTERHLPARAHPGFRGTAVYASP
.... .     .      . .. .  .| ..| ||. ||.||. || |. .       .  . ..|.| . ||    .     . |    |||.  |.. 
CMMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQIRQPRPITPFRGCKDYCPC

NAHMHQDLSRRDDLISWFYLVIDVMAGP--LPWK
  |  ....||||. ||||. ..   .   | ||
SCHQCREHGRRDDMESWFYMLYHLVHNTRGLSWK
Kinase 84692.m00144.AA S_TKc 10-289 19 3e-21 77.84 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-289
Range on HMM: 1-231/231
Sequence Identity: 19% (59 aa)

YTVGPKIGAGAFGEIYAVRNAGDNKIFALKVEPLSNRRNILELEASVLKRLSPCPYFPKFRIFGRTSTYSWLVMELLGP---SLSTVVKRLPSGR----L
|... ||| ||||. | .|. ....|.|.|. .     . .. | ..||.   .|.  |.  . .. .. ..|||...    .| .. |. ....    .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

SMSTGLRVANSILCGLESMHKKGFIHRDVKPSNILLRRSREYPIAIIDFGLSRVYVDRKTERHLPARAHPGFRGTAVYASPNAHMHQDLSRRDDLISWFY
.  .  ...  |.|.|| .|..|.||||.||.|||| .     | |.||||.|..                | ||  | .|               .. .
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL--------------TTFCGTPWYMAPEVL------------GYGK

----------LVIDVMAGPLPWKKLENRAEILHMKRRISISNLSDQIAHQLTLIWDHIQSLGFTDAPNYAYMHDLLREACEQN-----NVHQSDE--WDW
          ...  ..|  |.    . ...... .                                   . |..|  .. .      . .  .  ||.
CKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG--------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDI

--HPQI
  || .
KCHPWF
Kinase 84692.m00144.AA TyrKc 10-239 18 3e-06 -121.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 10-239
Range on HMM: 1-280/280
Sequence Identity: 18% (53 aa)

YTVGPKIGAGAFGEIYAVRNAGDNKIFALKVEPLSNRRNILELEASVLKRL-SPCPYFPKFRIFGRTS-------TYSWLVMELLGP-SLSTVVKRLPSG
 | | |.| |||||.|  .        | |.   .  |  .  ||.....|    |   ..    ...          ..|||.    .|    ..    
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

RLSMSTGLRVANSILCGLESMHKKGFIHRDVKPSNILLRRSREYPIAIIDFGLSRVYVDR----KTERHLPARAHPGFR--GTAVYASPNAHMHQ-----
 |.|.. |  .  | || |  |.|..||||    |.|. . .   . | ||||||   |       .    .. | | .        .| . ..      
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

-----------------DLSRRDDL---ISWFYLVIDVMAGPLPWKKLE--------NRAEI---------LHMKRRISISNLSDQI
                 .    ..    .|.. .. .|..|  . .  .          .|.            . | . |.. ...
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 84692.m00144.AA APH 125-156 20 0.000922 13.71 Pfam 171-204 (248) Show / Hide 
Range on Protein: 125-156
Range on HMM: 171-204/248
Sequence Identity: 20% (7 aa)

GFIHRDVKPSNILLR-RSR-EYPIAIIDFGLSRV
...|.|..| |.... |.. .  ...||.. ...
CWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACW