Gene 93148.m00098 (T.vaginalis)

93148.m00098

Species: T.vaginalis
Alias: 93148.m00098, TvagK0688
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
93148.m00098.AA Protein None 800 None Fasta, JSON
93148.m00098.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of 93148.m00098.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93148.m00098.AA NEK 4-258 50 2.6e-155 522.24 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-286/286
Sequence Identity: 50% (143 aa)

YTTIKVLGEGGYGKALLVEAKSDKQK-----YVVKEVRMANLKPQEKLDAK-KEVDVLHALNHPNIVKYVESFQENG--RLYIVMEYAD-GGDLSQL---
|. ||..|.| .||. .|. |||...     || |.. | |....|| .|  .|| .|  |.||||||| .||.|..  .|.|||||.. ||||.|.   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IERR--GRKLLSESDVMHYFIQIALALKYMHDR-----KILHRDLKGQNVFLCKNGK----VKLGDFGIAKVLDSTAQLCKT-QIGTPYYLSPEICEGRR
|...   .|...|. ....|||..|||||||||     ||||||.| ||.|| ||..    ||.|||||.|||..|... .| |.|||||.|||.|... 
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP

YNSKTDIWSLGCILYELCTL--HHPFDAS--NMNALLACIIRG-RYSPISSQ--YSSDLRNLVSRMLTKDTKPRPSINQIIMLPFI
||.| |||||||.|||.|||   |||.|.  ||..|   |..|  |.||.|.  ||.||.||.|.||.|| . |||.|||. .|||
YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 93148.m00098.AA NEK1 4-258 53 2.4e-149 502.45 In-house 1-276 (276) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-276/276
Sequence Identity: 53% (147 aa)

YTTIKVLGEGGYGKALLVEAKSDKQKYVVKEVRMANLKPQEKLDAKKEVDVLHALNHPNIVKYVESFQENGR--LYIVMEYADGGDLSQLIERR--GRKL
|. ||..||| .|||.||  |.| | || || .  . ...|. ....|| .|  . ||||||| |||.|||.  |||||||.||||| | |.|.    ||
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

LSESDVMHYFIQIALALKYMHDRKILHRDLKGQNVFLC--KNG---------------KVKLGDFGIAKVLDSTAQLCKTQIGTPYYLSPEICEGRRYNS
 ||   ||.|.|| |||...|||||||||.| ||.||   |||               .|||||||||..| .|  . .| ||||||||||||. . || 
FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN

KTDIWSLGCILYELCTLHHPFDASNMNALLACIIRGRYSPISSQYSSDLRNLVSRMLTKDTKPRPSINQIIMLPFI
|.|||||||.||||||| |||.| |. .|   |..|.|.||.. || .|..||| |. .. . |||.|||   |||
KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase 93148.m00098.AA NEK8 4-258 41 1.5e-129 372.1 In-house 1-278 (278) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-278/278
Sequence Identity: 41% (114 aa)

YTTIKVLGEGGYGKALLVEAKSDK--QKYVVKEVRMANLKPQEKLDAKKEVDVLHALNHPNIVKYVESFQENGRLYIVMEYADGGDLSQLIERRGRKLLS
|. | |.| |  | . |   |.|   .. . |.. |  . . |  .|  |..||  |.||||. | ..| |.. | |.||||||| | |.| ..  ||..
YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQHQQNKLFE

ESD-----------------VMHYFIQIALALKYMHDRKILHRDLKGQNVFLCKN-GKVKLGDFGIAKVLDST--AQLCKTQIGTPYYLSPEICEGRRYN
|                   . .||.|. .|. .||.  ||||||| ||.|. .  . ||.|||||.|.. .   .|  || .|||||.|||.|||. ||
EERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYN

SKTDIWSLGCILYELCTLHHPFDASNMNALLACIIRG-RYSPISSQYSSDLRNLVSRMLTKDTKPRPSINQIIMLPFI
 | |.|.|||.|||.|.|   |.|||  ||   |...  | |||..||...| ||.  | .|.  |||  ||   | .
QKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase 93148.m00098.AA NEK4 4-258 48 1.8e-111 376.63 In-house 1-257 (257) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-257/257
Sequence Identity: 48% (125 aa)

YTTIKVLGEGGYGKALLVEAKSDKQKYVVKEVRMANLKPQEKLDAKKEVDVLHALNHPNIVKYVESFQ-ENG-RLYIVMEYADGGDLSQLIERRGRKLLS
|  .|| | | ||   ||  . || .||.| . . |   .|. .| .|. .|  | |||||.| ||.. |||  ||||| . .|||| .   ..  ..|.
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQFLE

ESDVMHYFIQIALALKYMHDRKILHRDLKGQNVFLCKNGKVKLGDFGIAKVLDSTAQLCKTQIGTPYYLSPEICEGRRYNSKTDIWSLGCILYELCTLHH
|. |.  |.|||.|| |||...||||||| ||.|| |   .|.|||||..||.  ... || ||||||.|||.   | |. | ||||||| .||. || |
EYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITLKH

PFDASNMNALLACIIRGRYSPISSQYSSDLRNLVSRMLTKDTKPRPSINQIIMLPFI
 ||| .|| |.  || |.  |.. .|| || |||  || |  . |||| .|.  |.|
AFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase 93148.m00098.AA S_TKc 4-258 30 4.4e-99 336.38 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-231/231
Sequence Identity: 30% (82 aa)

YTTIKVLGEGGYGKALLVEAKSDKQKYVVKEVRMANLKPQEKLDAKKEVDVLHALNHPNIVKYVESFQENGRLYIVMEYADG--GDLSQLIERRGR----
|. ....|.|..||  ..  |...... .|...          ....|...|.  .||||||. ..||. ..||.||||.||  ||| ..|..|||    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

KLLSESDVMHYFIQIALALKYMHDRKILHRDLKGQNVFLCKNGKVKLGDFGIAKVLDSTAQLCKTQIGTPYYLSPEICEGRRYNS-KTDIWSLGCILYEL
. ..| .. .|. ||..||.|.|...|.||||| .|..|..   .|..|||.|..|       .|..|||.|..||..    |.  | |.||.||||||.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

CTLHHPFDASNMNALLACIIRGRYSPISSQYSSDLRNLVSRMLTKDTKPRPSINQIIM-------LPFI
..   ||.     ...  .|.          |..........|.|| . ||.. ..          |..
LCGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 93148.m00098.AA CAMK 9-258 21 2.5e-86 278.08 In-house 1-425 (425) Show / Hide 
Range on Protein: 9-258
Range on HMM: 1-425/425
Sequence Identity: 21% (93 aa)

VLGEGGYGKALLVEAKSDK------------QKYVVKEVRMANLK--------------------------PQEKLDAKKEVDVLHA-------LNHPNI
.||.|..||  |.. |...            ||. .| .    ||                          |. .   ..|....         |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKYVESFQENG-------------------RLYIVM---EYADGG----DLSQLIERRGR-------------KLLSESDVMHYFIQIALALKYMHDRKI
.|  | .. .                    ..|.||   ||..||    || . | ..|.             . ..|... .|| ||. |..|.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDLKGQNVFLCKN-----------------GKVKLGDFGIAKVLDS-----------------------TAQLCKTQIGTPYYLS-PEICEG------
 |||||  |. |..|                 ...|. ||| |...|.                       . |..||. |||.| . ||. .|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------RRYNSKTDIWSLGCILYELCTLHHPFDAS-------------NMNALLACIIRGRYS-P------------------ISSQ----YSSDLRN
        . |. |.|.||.|.||| . . . ||...             |.. |.  |..|.|. |                  || .     | . ..
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LVSRMLTKDTKPRPSINQIIMLPFI
|...||..| . |..| |.   |..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 93148.m00098.AA Pkinase 4-258 28 2.5e-84 291.26 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-293/293
Sequence Identity: 28% (85 aa)

YTTIKVLGEGGYGKALLVEAKSDKQKYVVKEVRMANLKPQEKLDAKK--EVDVLHALNHPNIVKYVESFQENGRLYIVMEYADGG----DLSQLIE-RRG
|......|.|..|.  .   |.. ....||...  . |....  . .  |. ... |||||||.. ..|......|.||||..||    ||. .|. .|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RKL-LSESDVMHYFIQIALALKYMHDRKILHRDLKGQNVFLCKNGKV----KLGDFGIAKVL-DSTAQLCKTQIGTPYYLSPEICE-GRRYNSKTDIWSL
... .|| .. .|. ||. .|.|.|...|.||||| .|... .|| .    |..|||.||..     . ..|  |||.|..||..  |. | .| |.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCILYELCTLHHPFDAS----NMNALLACIIRGRYSPISSQYS-----------------------SDLRNLVSRMLTKDTKPRPSINQIIMLPFI
||||||... . ||. .    | .  ...| | .. |......                       .... .....|.|| | ||.. ||   |..
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 93148.m00098.AA NEK2 4-258 33 5.6e-78 262.15 In-house 1-319 (319) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-319/319
Sequence Identity: 33% (106 aa)

YTTIKVLGEGGYGKALLVEAKSDKQKYVVKEVRMANLKPQEKLDAKKEVDVLHALNHPNIVKYVESF--QENGRLYIVMEYADGGDLSQLIE--RRGRKL
|   ...|.| .|.   |  |||.   | ||    ..   |.     |. .|  | |||||.|       .| .|||||||  ||||||.|   |  |. 
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

LSESDVMHYFIQIALALKYMHD---------------------RKILHRDLKGQNVFLCKNGK-------------------------------------
. |. .   . |. .||.  |                      . |||||.|  |.||  ..                                      
MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQ

--VKLGDFGIAKVLDSTAQLCKTQIGTPYYLSPEICEGRRYNSKTDIWSLGCILYELCTLHHPFDASNMNALLACIIRGRYSPISSQYSSDLRNLVSRML
  ||||||| |..|    .  .| .||||| |||  .|. || | ||||.||..||.|.|| || | |  .|   |  |....| .|||..|  ....|.
VVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMI

TKDTKPRPSINQIIMLPFI
  | . ||||. |.  |.|
NVDHYHRPSIEEILQHPQI
Kinase 93148.m00098.AA NEK-Unclassified 4-258 37 6.4e-78 257.52 In-house 1-258 (258) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-258/258
Sequence Identity: 37% (98 aa)

YTTIKVLGEGGYGKALLVEAKSDKQKYVVKEVRMANLKPQEKLDAKKEVDVLHALNHPNIVKYVESFQENGRLYIVMEYADGGDLSQLIERRGRK--LLS
|  |  || || |   ||  .  |   | .   ..  | . |   |  . .|  | || || | .|| || .|.   .| |||.| ..| ..  |   . 
YDKITTLGQGGGGAVYLVRHQISKRHLVQQ---ISKRKKKKKRQNK--IIILSQLRHPHIVTYHDSFFENAKLFYTQDYCDGGNLDRRIQKHRKKNEPFD

ESDVMHYFIQIALALKYMHDRKILHRDLKGQNVFLCKNGKVKLGDFGIAKVLDSTAQLCKTQIGTPYYLSPEICEGRRYNSKTDIWSLGCILYELCTLHH
|  .|  .||.  |. | | |||.||||| ||.|| .   | .|||||....| |    .| .||. ..|||.|.   || . |.||||||.||.||   
EGRIMQWCIQMIMAVQYIHQRKIIHRDLKPQNIFLTDDDTVSMGDFGISRIMDHTRDKARTCVGTMCWMSPEVCQDQPYNNRSDVWSLGCIIYEMCTCEP

PFDASNMNALLACIIRGRY------SPISSQYSSDLRNLVSRMLTKDTKPRPSINQIIMLPFI
 ||. ||  ..  | ..         |.|. || || ...  || ..   |||   |. ...|
FFDTHNMGEVYMKIKQDDNRLEEALEPVSKTYSTDLQQVIRFMLRRNFQQRPSATEIVEQDYI
Kinase 93148.m00098.AA ULK 4-258 28 2.2e-74 253.46 In-house 1-329 (329) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-329/329
Sequence Identity: 28% (93 aa)

YTTIKVLGEGGYGKALLVE-AKSD---KQKYVVKEVRMANLKPQEKLDA--------KKEVDVLHALN--------HPNIVKYVESFQENGR--LYIVME
|  ...||.| .||    .  |..   ..|...| .    .. .....         |.|..... |.        ||||||. . |..     .||.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YADGGDLSQLIERRGR--------KLLSESDVMHYFIQIALALKYMHDRKILHRDLKGQNVFLCK-NGK-----------VKLGDFGIAKVLDST---AQ
| .||||.|.|.....        | |||. . ..|.||. ..|..|...| |||.| ||. . . ..|           .|..||| ||..|.    .|
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LCKTQI------GTPYYLSPEICEGR----RYN-SKTDIWSLGCILYELCTLHHPFDASNMNALLACIIRGR------------YSPIS-------SQYS
. .|.       |||.| .|.| .|.     |. .|.||||||||.||. .   || |.  | .   ||.                |.         | |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

SDLRNLVSRMLTKDTKPRPSINQIIMLPFI
.....| .|||..| | | |. ...  |..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 93148.m00098.AA ULK 4-258 28 5.4e-74 252.13 In-house 1-324 (324) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-324/324
Sequence Identity: 28% (91 aa)

YTTIKVLGEGGYG-KALLVE-AKSD--KQKYVVKEVRMANLKPQEKLDA--------KKEVDVLHALN---HPN--IVKYVESFQENGR--LYIVMEYAD
|  ...||.| .| |    .  |..  .|.. .| . . ... .....         |.|. ..  |.   |||  |||. . |..     .||.||| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLSQLIERRGR-------KLLSESDVMHYFIQIALALKYMHDRKILHRDLKGQNVFLCK-NGK-----------VKLGDFGIAKVLD---STAQLCKT
||||.|.|.....       | |||. . ..|.||. ..|..|...| |||.| ||  . . ..|           .|..||| ||..|     .|.|.|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

QI------GTPYYLSPEICEGR----RYN-SKTDIWSLGCILYELCTLHHPFDASNMNALL-------------ACIIRGRYSPIS-----SQYSSDLRN
.       |||.| .|.| .|.     |. .|.||||||||.||. .   || ..  | .                .|. .  ..       . |.....
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LVSRMLTKDTKPRPSINQIIMLPFI
| .|||..| | | |. .|.  |..
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 93148.m00098.AA Ciliate-E2 4-258 22 1.8e-71 243.79 In-house 1-365 (365) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-365/365
Sequence Identity: 22% (85 aa)

YTTIKVLGEGGYGKALLVEAKSDKQ------------------KYVVKEVRMANLKPQEKLDAKKEVDVLHALN----------------HPNIVKYVES
|  ||..|.|..|.  ... .....                  |. .|.. | ..|....   |.| ...  .|                ||||.|..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--ENGRLYIVMEYADGGDLSQLIERR----------GRKLLSESDVMHYFIQIAL---------------ALKYMHDRK-ILHRDLKGQNVFLCKNGK
||   .  .|.||||..|||| ..|. .          . | ..|  . ... ||.                ||.|.| .. |.|||.| .|...     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKLGDFGIAKVLDS-------------------------------TAQLCKTQIGTPYYLSPEICE---------GRRYNSKTDIWSLGCILYELCTLHH
.|. |||..| .|                                  .. .|..|||.|..||| .         . .|. | ||||||.||||...  .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFDASNMNALLACIIRGRYSP-------------ISSQYSSDLRNLVSR----MLTKDTKPRPS-INQIIMLPFI
||    ..  . | |. .                .  . | .  .| ..    || || . |.. ..||.  |..
PF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 93148.m00098.AA Pkinase_Tyr 4-199 26 1.2e-30 104.42 Pfam 1-210 (270) Show / Hide 
Range on Protein: 4-199
Range on HMM: 1-210/270
Sequence Identity: 26% (56 aa)

YTTIKVLGEGGYGKALLVEAK----SDKQKYVVKEVRMANLKPQE--KLDAKKEVDVLHAL-NHPNIVKYVESFQ-ENGR--LYIVMEYADGGDLSQLIE
 | .|.|||| .|.  . ..|    ..|..  || .   .  ...  . |  .|. ... | .|||||...     . .   .||||||. .|||     
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

RR--GRKLLSESDVMHYFIQIALALKYMHDRKILHRDLKGQNVFLCKNGKVKLGDFGIAKVLDSTAQL-CKTQ---IGTPYYLSPEICEGRRYNSKTDIW
..  ... |. .|  .. .||| .. | ..... ||||   |. . .|..|| .||| |. . .. .   |..   .  . . .||    .....|.|.|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM-APECINYGKFTTKSDVW

SLGCILYELCTL
| |  ..|..|.
SFGVLMWEIFTY
Kinase 93148.m00098.AA TyrKc 4-258 21 4.6e-28 100.48 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-258
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YTTIKVLGEGGYGKALLVEAKSDKQKYVVKEVRMANLKPQEKLDAKKEVDVLHAL--NHPNIVKYVESFQEN-------GRLYIVMEYADGGDLSQLIER
 | .|.|||| .|.  . ..|   ..  || ..        . |  .|  ... |  .|||||. .    .        . |.|||||...||| . . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

RGRKLLSESDVMHYFIQIALALKYMHDRKILHRDLKGQNVFLCKNGKVKLGDFGIAKVLDST-------AQLCKTQ-IGTP-----YYLSPEICEGRRYN
...| |. .|  .. .|||    | |.... ||||   |. . .|. || .||| .. ...            |..  |.        ..||    ....
HRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

SKTDIWSLGCILYELCTL-HHPFDA-----SNMNALLACIIRGRYSPISSQ--------YSSDLRNLVSRMLTKDTKPRPSINQIIMLPFI
.|.|.|| |  ..|..|.   |         .   ..... .|.. |.            .... .. ..    | . ||. ..|    ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF