Gene 82576.m00127 (T.vaginalis)

82576.m00127

Species: T.vaginalis
Alias: TvagK0770, 82576.m00127
External Links:
Annotation:

Classification

Group: Other
Family: PLK
Subfamily: PLK1

Sequence

Name Sequence Type Origin Length Description Download
82576.m00127.AA Protein None 508 None Fasta, JSON
82576.m00127.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of 82576.m00127.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82576.m00127.AA PLK 23-279 48 9.20000000001e-123 401.55 In-house 1-258 (258) Show / Hide 
Range on Protein: 23-279
Range on HMM: 1-258/258
Sequence Identity: 48% (124 aa)

YTRHEELGHGGFATVFRVTDQANGEDYAMKVVPKARVSKPKSLEKMKSEIKIQSSLNHVNVVKAYGSFEDEINYYIIIELCPGHSIRDIIKKE-GFLKED
|.| . || |||| ....|| .... || |||||... ||.  ||||.||.|...|.| |.|| . .|||. | ||  |.|...|  ...|.    | |.
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

VVVQYTRDVLEGLSYLHDNRIIHRDLKIENFLFGSDGKIKIADFGLSAQLDYDNEKKFTVCGTPNYISPELLTQAFKGHSYEVDIWAIGVCVFAMLYGTP
 | .|.. . .|| |||..||||||||. |... ..  .||.||||...|.|| |.| |.|||||||.|| |    .|||||||.|..|. . ..| |.|
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFETAKTKETYEQIKHCQYKFPCYPIVSDEAKDFIQSTLKLDPKERPNCQELLAHPFI
||||.  ||||. |||..| || ....||||||.||. |. .| |||.  ..| ||| 
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase 82576.m00127.AA PLK-Unclassified 23-279 44 1.6e-115 390.09 In-house 1-264 (264) Show / Hide 
Range on Protein: 23-279
Range on HMM: 1-264/264
Sequence Identity: 44% (118 aa)

YTRHEELGHGGFATVFRVTDQANGEDYAMKVVPKARVSKPKSLEKMKSEIKIQSSLNHVNVVKAYGSFEDEINYYIIIELCPGHSIRDIIKKE-------
| | . || |||| .. |..  . . || |..||.   | .  .| .|||||..||.| |.|| . .|||. | ||  |.||.... ..||.        
YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK

GFLKEDVVVQYTRDVLEGLSYLHDNRIIHRDLKIENFLFGSDGKIKIADFGLSAQLDYDNEKKFTVCGTPNYISPELLTQAFKGHSYEVDIWAIGVCVFA
  | |. |  ||  ....| |||.|||||||||. | ..... ..||.||||.. | .| ||| |.|||||||.|| |    .|||||||.|..|. . .
KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILYT

MLYGTPPFETAKTKETYEQIKHCQYKFPCYPIVSDEAKDFIQSTLKLDPKERPNCQELLAHPFI
.| | |||||   | ||. ||  ||.||  ...||.|||.||. |...|..||.  ....||| 
LLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY
Kinase 82576.m00127.AA AGC 23-279 22 3.8e-105 272.24 In-house 1-395 (395) Show / Hide 
Range on Protein: 23-279
Range on HMM: 1-395/395
Sequence Identity: 22% (90 aa)

YTRHEELGHGGFATVFRVTDQ------ANGEDYAMKVVPKAR-VSKPK--SLEKMKSE------------IKIQSSLN----------HVNVVK-AYGSF
.  .  .| |.| .|. | .       ..|. |||||. |.. . . |   .|. ..|             .| . .|          | ..||  . ||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EDEIN--YYIIIELCP---------GH-SIRDIIK---KEGFLKEDVVVQYTRD-------VLEGLSYLHD-NRIIHRD-LKIENFLFGSDGKIKIADFG
.|. .   |.. |..|         |      ...   ||| . |...  |.         .. .| |||. . ||||| || || |. .|| ||..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSAQLDYDN--------------------------------------------------EKKFTVCG--TPNYISPELLTQAFKGHSYEVDIWA--IGVC
|. ..  |.                                                  ..  | ||  ||.|..|| |      .....|.|.   |..
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL------YGKACDWWSFGLGCL

VFAMLYGTPPFETA----------KTKETYEQIKHCQYKFPCYPI--------------VSDEAKDFIQSTLKLDPKERPNC----------QELLAHPF
 . ||.| |||               .|....|....|.... .               .|.||||.|.  |. ||..|. |          .|. .||.
MYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPW

I
 
F
Kinase 82576.m00127.AA CAMK 28-279 20 3.7e-98 316.91 In-house 1-425 (425) Show / Hide 
Range on Protein: 28-279
Range on HMM: 1-425/425
Sequence Identity: 20% (87 aa)

ELGHGGFATVFRVTDQANG------------EDYAMKVVPKARVSK-------------------------PKSLEKMKSEIKIQSS-------LNHVNV
.||.|.|..|.....  ..            . .|.|...| ....                         ||.......||.| ..       |.| |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKAYGSFED-------------------EINYYIII---ELCPGH----SIRDIIKKEGF---------------LKEDVVVQYTRDVLEGLSYLHDNRI
.| |  .||                   . ..|..    |.|.|      . | |.. |                ..|. . .| | ..... |.|.. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKIENFLFGSD-----------------GKIKIADFGLSAQLDY-----------------------DNEKKFTVCGTPNYIS-PELLTQ----AF
.||||| || |. ..                 ..|||.|||.....|                        ...|  |.|||| |.. ||.| .    ..
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------KGHSYEVDIWAIGVCVFAMLYGTPPFETA-------------KTKETYEQIKHCQYKFPCYPI--------------VSDE--------AKD
        .......|.|..||  ..|| |.|||.                 .|..|.|. ..| || ...              .|||        .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FIQSTLKLDPKERPNCQELLAHPFI
.|.. |. ||..|..... |.||..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 82576.m00127.AA S_TKc 23-279 32 8.7e-98 332.09 SMART 1-231 (231) Show / Hide 
Range on Protein: 23-279
Range on HMM: 1-231/231
Sequence Identity: 32% (88 aa)

YTRHEELGHGGFATVFRVTDQANGEDYAMKVVPKARVSKPKSLEKMKSEIKIQSSLNHVNVVKAYGSFEDEINYYIIIELCPG--HSIRDIIKKEGF---
|. ....|.|.|..|.....   |. .|.|...          |....||.| .. .| |.|| |..|.|  ..|.. |.|.|   . .|.||| |    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LKEDVVVQYTRDVLEGLSYLHDNRIIHRDLKIENFLFGSDGKIKIADFGLSAQLDYDNEKKFTVCGTPNYISPELLTQAFKGHSY-EVDIWAIGVCV
   . | ..  |.. ....| |.|...||||||| || |. .   |||.||||..||        |.||||.|..||.|     |... ..|.|..|...
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCIL

FAMLYGTPPFETAKTKETYEQIKHCQYKFPCYPIVSDEAKDFIQSTLKLDPKERPNCQELLA-------HPFI
. ||.| |||.    ......|.            |.||||||.  |. ||..|| . |.|.       ||..
YEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 82576.m00127.AA PLK1 23-279 42 3.7e-92 303.24 In-house 1-253 (253) Show / Hide 
Range on Protein: 23-279
Range on HMM: 1-253/253
Sequence Identity: 42% (109 aa)

YTRHEELGHGGFATVFRVTDQANGEDYAMKVVPKARVSKPKSLEKMKSEIKIQSSLNHVNVVKAYGSFEDEINYYIIIELCPGHSIRDIIKKEGFLKEDV
|.. . ||.||||  . ..|..  | .| |||||. . |..  .||  ||.|  .|.| ..|| .  |||. | ||..|||  .|. .. |. . . |  
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE

VVQYTRDVLEGLSYLHDNRIIHRDLKIENFLFGSDGKIKIADFGLSAQLDYDNEKKFTVCGTPNYISPELLTQAFKGHSYEVDIWAIGVCVFAMLYGTPP
   |.. ..||  |||.|.|||||||. |  .  . ..|| ||||  ...|| |.| | ||||||| ||.|..  ||||.|||||.||  .. .|.| ||
CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLNK--KGHSFEVDIWSIGCIMYILLFGQPP

FETAKTKETYEQIKHCQYKFPCYPIVSDEAKDFIQSTLKLDPKERPNCQELLAHPFI
||| . |||| .||...|. | .  .|  |...|.. |. ||..||. ...|   |.
FETKCLKETYSRIKKNEYRIPSH--ISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase 82576.m00127.AA Pkinase 23-279 31 2.9e-89 307.65 Pfam 1-293 (293) Show / Hide 
Range on Protein: 23-279
Range on HMM: 1-293/293
Sequence Identity: 31% (92 aa)

YTRHEELGHGGFATVFRVTDQANGEDYAMKVVPKARVSKPKSLEKMK-SEIKIQSSLNHVNVVKAYGSFEDEINYYIIIELCPGH----SIRDIIK--KE
|.... .| |.|..|.. ... .|. .|.|...| . .. |  .. . |||.|  .||| |.|. |..|||. ..|.. |.|.|     .  |.|.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GFL--KEDVVVQYTRDVLEGLSYLHDNRIIHRDLKIENFLFGSDGKI----KIADFGLSAQL-DYDNEKKFTVCGTPNYISPELLTQAFKGHSYEVDIWA
| .   |...  | . .|.|| |.|...||||||| ||.|. ..| |    ||.||||..|.    |.   |.||||.|..||..    ......||.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPKVDMWS

IGVCVFAMLYGTPPFETA------KTKETYEQIKHCQYKFPCYPIVS-------------------DEAKDFIQSTLKLDPKERPNCQELLAHPFI
.|. .. || | |||  .        .. ...|......|...   |                   .|.|||| . |..|||.||.....| ||..
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 82576.m00127.AA CAMKL 23-279 28 1.3e-84 269.9 In-house 1-297 (297) Show / Hide 
Range on Protein: 23-279
Range on HMM: 1-297/297
Sequence Identity: 28% (85 aa)

YTRHEELGHGGFATVFRVTD-QANGEDYAMKVVPKARVS-KPKSLEK-----------MKSEIKIQSSLN---HVNVVKAYGSFEDEIN------YYIII
|.  ..||.|.|..|   |. . .|| .|.|.. | . . .|... .            . ||.|...||   | |..| |  .|.. .      .|.. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCPGHS--IRDIIKKEGF----LKEDVVVQYTRDVLEGLSYLHDNRIIHRDLKIENFLFGSDG--KIKIADFGLSAQLD-Y---DNEKKFTVCGTPNYI
|.|.| .    | |.|.|     ..|.   .| | ......|.|...|.|||.| || |. ..|  .|||.|||.|.. . .   ...|  | ||.|.| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPELLTQ-AFKGHSYEVDIWAIGVCVFAMLYGTPPFETAKTK-------ETYEQIKHCQYKFPCYPIVSDEAKDFIQSTLKLDPKERPNCQELLAHPFI
.||..     . . ..||||..||  .||..|. ||. .  .       . |..|. . |..| .. || ...|.|.. |. .|..||...... ||. 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 82576.m00127.AA Ciliate-E2 23-279 26 1.7e-83 283.7 In-house 1-365 (365) Show / Hide 
Range on Protein: 23-279
Range on HMM: 1-365/365
Sequence Identity: 26% (100 aa)

YTRHEELGHGGFATVFRVTD-----------------------QANGEDYAMKVVPKARVSKPKSLEKMKSEIK----------IQSSLNHVNVVKAYGS
|  .. .| |.|..|.....                       ....  ||||.. |  .   |. ...  ||.          |...||| |..| | .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--DEINYYIIIELCPGHSIRDIIK------------KEGFLKEDVVVQYTRDVLE---------------GLSYLHDNR-IIHRDLKIENFLFGSDGK
|.  |. |.|.. |.| | . .|.||            . . ..|  . .... .|.               .| ||| .  |||||.| || ||     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKIADFGLSAQLDYDNEKK-------------------------------FTVCGTPNYISPELLT-------QAFKGHSYEVDIWAIGVCVFAMLYGTP
|||.||||| ..| ||...                               .|.||||.| .|| |        |..||..|..|||..||. . ||.| |
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFETAKTKETYEQIKHCQYKFPCY----------------PIVSDEAKDFIQS----TLKLDPKERPN-CQELLAHPFI
||        ..||| |...|||.                  .|.|.||.|.      |. ||..|..  ...| ||..
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 82576.m00127.AA PLK2 23-279 42 9e-82 263.06 In-house 1-257 (257) Show / Hide 
Range on Protein: 23-279
Range on HMM: 1-257/257
Sequence Identity: 42% (111 aa)

YTRHEELGHGGFATVFRVTDQANGEDYAMKVVPKARVSKPKSLEKMKSEIKIQSSLNHVNVVKAYGSFEDEINYYIIIELCPG----HSIRDIIKKEGFL
|.|   || ||||  .  ||  ..  ||.|.||. ||.||.  |||  || . . | | ..|. .  |||  | ||. |.|       |.  . |    |
YCRGKLLGKGGFARCYEMTDMDTHYVYAVKIVPHSRVAKPHQREKMEREIELHRQLRHRHIVQFHHHFEDRDNIYILLEYCSRQVPLKSMAHMWKVRHHL

KEDVVVQYTRDVLEGLSYLHDNRIIHRDLKIENFLFGSDGKIKIADFGLSAQLDYDNEKKFTVCGTPNYISPELLTQAFKGHSYEVDIWAIGVCVFAMLY
 |  |  | | ...|| |||. .|||||||  ||       .|| |||| | |    . . | |||||||.|| |    .||| | |||| |   . || 
TEPEVRYYMRQIVSGLRYLHQQCIIHRDLKLGNFFINDNMEVKIGDFGLAARLEPEEHCHRTMCGTPNYIAPEVLNR--QGHSCESDIWALGCIMYTMLC

GTPPFETAKTKETYEQIKHCQYKFPCYPIVSDEAKDFIQSTLKLDPKERPNCQELLAHPFI
|.||||||  ||||  |.|  | .|     |  |.  | . |  ||..||   ... | | 
GRPPFETANLKETYRCIRHNHYHMPT--HLSPPARHLIARMLSPDPEDRPSLDHIIRHDFF
Kinase 82576.m00127.AA Ciliate-E2-Unclassified 23-279 27 2.3e-81 276.64 In-house 1-352 (352) Show / Hide 
Range on Protein: 23-279
Range on HMM: 1-352/352
Sequence Identity: 27% (99 aa)

YTRHEELGHGGFATVFRVTDQANGEDYAMKVVPKARVSKPKSLEKMKSEIKIQ-----------------------SSLNHVNVVKAYGSFEDEINYYII
|. .. .|.|||..|... .  ... ||||   |... | |. .... ||. .                       ....| ..|| .  |.|. | ||.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

IELCPGHSIRDIIKKEGF-----------------LKEDVVV-----QYTRDVLEGLSYLHDN-RIIHRDLKIENFLFGSDG---KIKIADFGLSAQLDY
 |.|.| . ...||| ..                 . |  ..     .|.. .|.||.||| .  |||||.| || || ..|   .|||.|||.| ....
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

DNEKKFTV----------------CGTPNYI----SPELLTQAFKGHS--YEVDIWAIGVCVFAMLYGTPPFE-TAKTK---------------ETYEQI
.|... |                 ||||||.    .||.| .   .||  |..|||. ||. ..||.|..||. . ...               . |..|
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KHCQYKFPCYP------IVSDEAKDFIQ----STLKLDPKERPNCQELLAHPFI
| ....||..|      ..|.||||||.    . || .|..|.. ...| ||..
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 82576.m00127.AA STE 23-279 25 4.6e-74 252.37 In-house 1-359 (359) Show / Hide 
Range on Protein: 23-279
Range on HMM: 1-359/359
Sequence Identity: 25% (94 aa)

YTRHEELGHGGFATVFRVTDQ------ANGED---------YAMKVVPKARVSK--------------PKSLEKMKSEIKIQSSLN--HVNVVKAYGSFE
... |..|.|.| ||..  .        .||          .|.|.... . ..              .. ... . |||| . .|  | |.|| ||...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DE-------INYYIIIELCPGHSIRDIIK-KEGFLK-------------EDVVVQYTRDVLEG-LSYLHDNRIIHRDLKIENFLFGSDGKIKIADFGLSA
.|        . .|. |...| |..|||| | | .|             |...  ..|..|.| |.|||...|||||.|  | |.     .|..|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLDYD----------------NEKKFTVCGTPNYISPELLTQA----FKGHSYEVDIWAIGVCVFAMLYGTPPFET-AKTKETYEQI--KHCQ-------
||. .                 .|  |..||| . .|| ..|      ||... .||| .| ..  |. | ||. .   ..  .. .  .|.|       
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---YKFPCYP--------------------IVSDEAKDFIQSTLKLDPKERPNCQELLA--HPFI
    . |  |                     .|.| ||||.  |. ||..||. ..||   ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 82576.m00127.AA TyrKc 23-279 23 8.7e-17 48.69 SMART 1-280 (280) Show / Hide 
Range on Protein: 23-279
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YTRHEELGHGGFATVFRVTDQANGEDYAMKVVPKARVSKPKSLEKMKSEIKIQSSL--NHVNVVKAYGSFEDE-------INYYIIIELCPGHSIRDII-
 |  ..||.| | .|.. |     .. | |.. .        .| . .|..| ..|  .| |.|. ||   ..         ..|. |..|. . .| . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KKEGFLKEDVVVQYTRDVLEGLSYLHDNRIIHRDLKIENFLFGSDGKIKIADFGLSAQLDYD-------NEKKFTV--CGTP----NYISPELLTQAFKG
|... |. .  ...  .. .| .|||....|||||   | | |... .||.|||||  .. |         .. .   .|         .|| .   .. 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGK

HSYEVDIWAIGVCVFAML-YGTPPFET-----AKTKETYEQIKHCQYKFPCYPI--------VSDEAKDFIQSTLKLDPKERPNCQELLAHPFI
 . . |.|. ||| . .. || .| .       . .| .|..|.  .  |. |          .||  . ...  . ||..||. .|.  | ..
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRM-PQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 82576.m00127.AA Pkinase_Tyr 23-168 27 3.1e-15 52.2 Pfam 1-158 (270) Show / Hide 
Range on Protein: 23-168
Range on HMM: 1-158/270
Sequence Identity: 27% (44 aa)

YTRHEELGHGGFATVFRVTDQ----ANGEDYAMKVVPKARVSKPK-SLEKMKSEIKIQSSL-NHVNVVKAYGSFE-DEIN--YYIIIELCPGHSIRDIIK
 |  ..||.| | .|.. |       .. . | |.. |   ...   .|.. .|.|| ..| .| |.|. ||    ..    .||. |..|. . .|  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K----EGFLKEDVVVQYTRDVLEGLSYLHDNRIIHRDLKIENFLFGSDGKIKIADFGLS
|    .. |.    .|. ... .|..||.....|||||   | | ......||.||||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
POLO_box 82576.m00127.AA POLO_box 335-371 33 7.6e-08 32.58 Pfam 1-39 (74) Show / Hide 
Range on Protein: 335-371
Range on HMM: 1-39/74
Sequence Identity: 33% (13 aa)

HSAKYGLGYLLIDGSVGAC-FNDLSRMIMDPYQE-FIQY
 . |||..|.| .|.|. . ||| ...|..| .. ...|
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTY
POLO_box 82576.m00127.AA POLO_box 431-458 41 0.000535 18.37 Pfam 1-29 (74) Show / Hide 
Range on Protein: 431-458
Range on HMM: 1-29/74
Sequence Identity: 41% (12 aa)

IRNDDATLFRLDNRNVQVN-FTDRTKVAL
 |.. .  ..| | .|||| |.| ||..|
YRTKYGIMYQLSNGTVQVNFFNDHTKIIL