Gene 95790.m00039 (T.vaginalis)

95790.m00039

Species: T.vaginalis
Alias: TvagK0121, 95790.m00039
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag4

Sequence

Name Sequence Type Origin Length Description Download
95790.m00039.AA Protein None 223 None Fasta, JSON
95790.m00039.kin_dom Protein Kinase Domain None 194 None Fasta, JSON

Protein domain

Protein domains of 95790.m00039.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 95790.m00039.AA CAMKL 12-204 38 1.6e-93 298.78 In-house 1-230 (297) Show / Hide 
Range on Protein: 12-204
Range on HMM: 1-230/297
Sequence Identity: 38% (88 aa)

YTLGRTLGKGTTGKVRIATK-QGSGQQYAIKIVKKSLFEAKPQLETK-----------IRREVGLMRLLN---HPHLLKFEECFESHRH------FYIVL
|..|.|||||. |||. ||  .  |...||||..|.    .|. . .           ||||. .|..||   ||.  |. |..|  .|      .|.|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAENGE--LFDFLIKR----KSLTLECGMHFFHELLYGLEYLHEHAICHRDLKPENILLDQFN--HIKIADFGFARWMR------SNIAETSCGSPHYA
||...||  |||...|.    .... .   ..|  .. ...|.|.| |.|||.||||||||. .   |||.||||. ..|       .  .|.||||.|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVIKG--STYDGRAADIWSLGVILFALL
|||...|    |||...||||.||||.|..
APEIFQGNNKPYDGPKVDIWSCGVILYAMV
Kinase 95790.m00039.AA CAMK 17-204 24 2e-87 281.67 In-house 1-328 (425) Show / Hide 
Range on Protein: 17-204
Range on HMM: 1-328/425
Sequence Identity: 24% (80 aa)

TLGKGTTGKVRIATKQGSG------------QQYAIKIVKKSLFEA------------------------KPQLETKIRREVGLMRL-------LNHPHL
|||.|. |||. ..   ..            |..||||..|.                            .|. . ..|||. .|..       |.||..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LKFEECFESHRH-------------------FYIVL---EYAENGEL----FDFLIKRKS---------------LTLECGMHFFHELLYGLEYLHEHAI
.|. | .|....                   .|.|.   ||...|||    ||.......               .| .   ..|. .. ...|.|.| |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

CHRDLKPENILLDQF-----------------NHIKIADFGFARWMRSNI-------------------------AETSCGSPHYAA-PEVIKG------
.||||||||||||.                  | |||.|||||. ....                           .|.||.|.|.| |||..|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------STYDGRAADIWSLGVILFALL
        .|.|...|.||.||||...|
QNATDEEKPYYGPKCDMWSCGVILYIML
Kinase 95790.m00039.AA NuaK 12-203 46 2.9e-86 226.69 In-house 1-192 (252) Show / Hide 
Range on Protein: 12-203
Range on HMM: 1-192/252
Sequence Identity: 46% (89 aa)

YTLGRTLGKGTTGKVRIATKQGSGQQYAIKIVKKSLFEAKPQLETKIRREVGLMRLLNHPHLLKFEECFESHRHFYIVLEYAENGELFDFLIKRKSLTLE
| . .|||||| |||. || . .|.. ||| .||.  |..  .  .||||. .|  |||||  .  | ||.     ||.|||  |||.|.. ..|||. .
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDM-VHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPER

CGMHFFHELLYGLEYLHEHAICHRDLKPENILLDQFNHIKIADFGFAR-WMRSNIAETSCGSPHYAAPEVIKGSTYDGRAADIWSLGVILFAL
   |||      . | | | ||||||| ||||||| . .||||||    .   .. .| |||| || ||.. |  | |   | |||||.|...
EARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTM
Kinase 95790.m00039.AA AMPK 12-204 43 8.8e-85 251.63 In-house 1-194 (254) Show / Hide 
Range on Protein: 12-204
Range on HMM: 1-194/254
Sequence Identity: 43% (85 aa)

YTLGRTLGKGTTGKVRIATKQGSGQQYAIKIVKKSLFEAKPQLETKIRREVGLMRLLNHPHLLKFEECF-ESHRHFYIVLEYAENGELFDFLIKRKSLTL
| .| |.|.|| ||| ..| .  |.. ||||  |     . .   .|.||. ...|..|||. .  |   |. . ...|.||. .|||||. .|.. |. 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQ-DMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQE

ECGMHFFHELLYGLEYLHEHAICHRDLKPENILLDQFNHIKIADFGFARWMRSNIA-ETSCGSPHYAAPEVIKGSTYDGRAADIWSLGVILFALL
.    ||   . |.||.|.| | ||||||||.|||. ..|||.|||    |  .    |.|||| |||||.| |  | |.  |||| ||||.|.|
REACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAML
Kinase 95790.m00039.AA BRSK 12-204 48 1.2e-83 284.26 In-house 1-194 (254) Show / Hide 
Range on Protein: 12-204
Range on HMM: 1-194/254
Sequence Identity: 48% (95 aa)

YTLGRTLGKGTTGKVRIATKQGSGQQYAIKIVKKSLFEAKPQLETKIRREVGLMRLLNHPHLLKFEECFESHRHFYIVLEYAENGELFDFLIKRKSLTLE
| |..|||||.||.|.. .   .|.  ||||. | .   |. .  |. ||. .|.| .||| .|  . .|  .  | .||. . |||||.|.|.  ||  
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

CGMHFFHELLYGLEYLHEHAICHRDLKPENILLDQFNHIKIADFGFARWMRSN-IAETSCGSPHYAAPEVIKGSTYDGRAADIWSLGVILFALL
    ||     .|.. | | |||||||||| |||  | ||||||| |   .   . .||||||||| ||||.|  |||| ||.|| ||||.|||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALL
Kinase 95790.m00039.AA Pkinase 12-204 38 1.4e-78 272.2 Pfam 1-206 (293) Show / Hide 
Range on Protein: 12-204
Range on HMM: 1-206/293
Sequence Identity: 38% (81 aa)

YTLGRTLGKGTTGKVRIATKQGSGQQYAIKIVKKSLFEAKPQLETKIR-REVGLMRLLNHPHLLKFEECFESHRHFYIVLEYAENG----ELFDFLI--K
|..||..|.|. |.|......|.|...|.||.||.  | . ...|..| .|. .|. ||||. ... ..||...| |.|.||.|.|    .|||..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

RKSL--TLECGMHFFHELLYGLEYLHEHAICHRDLKPENILLDQFNHI----KIADFGFAR---WMRSNIAETSCGSPHYAAPEVIKGSTYDGRAADIWS
....  . .   ... ..| ||||.|.. |.||||||||||.|. .||    ||.|||.|.   . ..  . | ||.|.|.|||||.|..|.|...|.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGVILFALL
.|.||. .|
CGCILYEML
Kinase 95790.m00039.AA MARK 12-204 36 2.9e-75 245.51 In-house 1-200 (262) Show / Hide 
Range on Protein: 12-204
Range on HMM: 1-200/262
Sequence Identity: 36% (74 aa)

YTLGRTLGKGTTGKVRIATKQGSGQQYAIKIVK-KSLFEAKPQLETKIRREVGLMRLLNHPHLLKFEECFE--SHRH-FYIVLEYAENGELFDFLIKR--
| ...|.|.|. .||. |. . .|...||||.. ..|..  ||   ...||. .|..|.||.  |. . .|    .| .|...|||..|||.|.....  
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLND--PQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPN

KSLTLECGMHFFHELLYGLEYLHEHAICHRDLKPENILLDQFN--HIKIADFGFARWM-RSNIAETSCGSPHYAAPEVIKGSTYDGRAADIWSLGVILFA
  |. |   ..|. ......|.|.. |.|||.||||||.|. .   |||.||||..     .  .| ||.| |.|||....  |||...|||||||.|..
GRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYF

LL
..
MV
Kinase 95790.m00039.AA CAMK1 12-204 35 3.6e-70 203.17 In-house 1-210 (276) Show / Hide 
Range on Protein: 12-204
Range on HMM: 1-210/276
Sequence Identity: 35% (77 aa)

YTLGRTLGKGTTGKVRIATKQGS---GQQYAIKIVKKSLFEAKPQLET-------KIRREVGLMRL---LNHPHLLKFEECFESHRHFYIVLEYAENGEL
| .| ..|.|. ..|. .|.  .   |.|||||. .|     | ....       ....|.. |.    ..||.  ||.| .|| .|||.|.|.  .|||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDK-----KKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGEL

FDFLIKRKSLTLECGMHFFHELLYGLEYLHEHAICHRDLKPENILL-DQFNH--IK--IADFGFARWMRSN--IAETSCGSPHYAAPEVIKG---STYDG
||  ..... | .   |  ...|  .||.|.. |.||||||||.|. |. ..  ||  ||||| ..   ..  . .| ||.| | ||||...     || 
FDRIVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYD-

RAADIWSLGVILFALL
 | |.|| |||.. ||
KACDMWSIGVITYILL
Kinase 95790.m00039.AA Ciliate-E2 12-204 26 6.6e-68 231.91 In-house 1-290 (365) Show / Hide 
Range on Protein: 12-204
Range on HMM: 1-290/365
Sequence Identity: 26% (77 aa)

YTLGRTLGKGTTGKVRIATK-----------------------QGSGQQYAIKIVKKSLFEAKPQLETKIR---------REVGLMRLLNHPHLLKFEEC
| . . .|.|. |.|. ...                       .  ...||.||.||.  |.. | .  .|          |  ....||||...|. ||
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--SHRHFYIVLEYAENGELFDFLIKR-----------KSLTLECGMHFFHELLY---------------GLEYLHEHA-ICHRDLKPENILLDQFNHI
|.  .  ..|.|.||.. |.|||.....           |..|..   ... ..|.               .|||||.   |.|||.||||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIADFGFAR-----------------WMRSN-----------------IAETSCGSPHYAAPEVIKGSTYDG--------RAADIWSLGVILFALL
||.|||...                 .|  .                 .. | ||.|.| |||...|  ||.         ..|||||||||. .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML
Kinase 95790.m00039.AA QIK 12-205 39 1.5e-65 224.13 In-house 1-213 (272) Show / Hide 
Range on Protein: 12-205
Range on HMM: 1-213/272
Sequence Identity: 39% (84 aa)

YTLGRTLGKGTTGKVRIATKQGSGQQYAIKIVKKSLFEAKPQLETKIRREVGLMRLLNHPHLLKFEECFESHRHFYIVLEYAENGELFDFLIKRKS----
|...||.|||  . |..|.     .. ||||. ||  ...  |. |. ||| .| .|.|||  |  .  |. .  ||| ||..|||.|| |.|       
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEE-NLQ-KCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVK

----------------LTLECGMHFFHELLYGLEYLHEHAICHRDLKPENILLDQFNHIKIADFGFARWMRSNI-AETSCGSPHYAAPEVIKGSTYDGRA
                .. .     | ... . .|.|.. | ||||| ||||||.   ||||||||  |  .    .| |||| |||||. .|  |||  
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK

ADIWSLGVILFALLA
.||||.||.|..| .
VDIWSMGVVLYVLVC
Kinase 95790.m00039.AA S_TKc 12-223 32 4.2e-64 220.18 SMART 1-220 (231) Show / Hide 
Range on Protein: 12-223
Range on HMM: 1-220/231
Sequence Identity: 32% (79 aa)

YTLGRTLGKGTTGKVRIATKQGSGQQYAIKIVKKSLFEAKPQLETKIRREVGLMRLLNHPHLLKFEECFESHRHFYIVLEYAEN--GELFDFLIKRKS--
|...|..|||. |||. ... ..|...||||.|            .||||. ...  .||.. |. ..|..  |.|.|.||...  |.|||.. ||..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LTLECGMHFFHELLYGLEYLHEHAICHRDLKPENILLDQFNHIKIADFGFARWMRSNIAETSCGSPHYAAPEVIKGSTYDGRAADIWSLGVILFAL
    ..     ....... .|||.|.| |.||||||||||||.  ||||.|||.|| .      | ||.|.| ||||.    |.....|.||.|.||. .
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LAVCIIFF------------------------NTS-RKSNIATVT
|. .  |                         . . | .     .
LCGYPPFPQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQ
Kinase 95790.m00039.AA GIN4 58-204 50 1.2e-60 192.28 In-house 81-229 (293) Show / Hide 
Range on Protein: 58-204
Range on HMM: 81-229/293
Sequence Identity: 50% (75 aa)

IRREVGLMRLLNHPHLLKFEECFESHRHFYIVLEYAENGELFDFLIKRKSLTLECGMHFFHELLYGLEYLHEHAICHRDLKPENILLDQFNH-IKIADFG
| ||. .|.|..||  ..  . .| .   |.|||||| ||||..|...  |     .|.|. .. |. | |   ||||||||||.|||.... |||||||
IEREIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFG

FARW-MRSNIAETSCGSPHYAAPEVIKGSTYDGRAADIWSLGVILFALL
 |   . ... |||||||||||||.. |  |.| |.|.|| ||||||||
MAALETDNKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALL
Kinase 95790.m00039.AA Pkinase_Tyr 12-159 29 4.1e-20 68.74 Pfam 1-159 (270) Show / Hide 
Range on Protein: 12-159
Range on HMM: 1-159/270
Sequence Identity: 29% (48 aa)

YTLGRTLGKGTTGKVRIATKQ----GSGQQYAIKIVKKSLFEAKPQL--ETKIRREVGLMRLL-NHPHLLKFEECFE-SHRH--FYIVLEYAENGELFDF
 |.|..||.|  |.|. .|      . ... |.|..|     | ..     .  ||. .|. | .||.....  .     ..   |||.||...| | |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LIK----RKSLTLECGMHFFHELLYGLEYLHEHAICHRDLKPENILLDQFNHIKIADFGFAR
| |    ...||..   .. ..   |.|||... . ||||   |.|..  |..||.||| ||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase 95790.m00039.AA TyrKc 12-222 19 4.4e-13 -11.17 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-222
Range on HMM: 1-280/280
Sequence Identity: 19% (58 aa)

YTLGRTLGKGTTGKVRIATKQGSGQQYAIKIVKKSLFEAKPQLETKIRREVGLMRLL--NHPHLLKFEECFESH-------RHFYIVLEYAENGELFDFL
 |||..|| |  |.|. .|     .| |.| .|..        .  ..||  .|. |  .||.....  .  ..          .||.||...| | |.|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

IKRKS-LTLECGMHFFHELLYGLEYLHEHAICHRDLKPENILLDQFNHIKIADFGFARWMRSN------IAETSC----GSP-----HYAAPEVIKGSTY
 |..  |...   .| .    | ||||.. . ||||   |.|..  ...||.||| .|   .           .     |.         |||.|. ...
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

DGRAADIWSLGVILFALLAVCIIFFNT---------------------SRKSN----------------------------------IATV
   . |.|| || .. ..  .                            .  |                                  .   
T-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 95790.m00039.AA GIN4 12-48 44 5.1e-12 34.25 In-house 1-38 (293) Show / Hide 
Range on Protein: 12-48
Range on HMM: 1-38/293
Sequence Identity: 44% (17 aa)

YTLGRTLGKGTTGKVRIATKQGSGQQYAIKIVK-KSLF
. ||.|||.| ||||..| ..  ||. |.|..  |..|
WKLGETLGFGSTGKVQLAKNMETGQRAAVKVISKKKIF