94984.m00243

Species: T.vaginalis
Alias: TvagK0843, 94984.m00243
External Links:
Annotation:

Classification

Group: CMGC
Family: RCK
Subfamily: MOK

Sequence

Name Sequence Type Origin Length Description Download
94984.m00243.AA Protein None 378 None Fasta, JSON
94984.m00243.kin_dom Protein Kinase Domain None 284 None Fasta, JSON

Protein domain

Protein domains of 94984.m00243.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94984.m00243.AA CMGC 11-294 20 1.7e-89 294.18 In-house 1-513 (513) Show / Hide
Range on Protein: 11-294
Range on HMM: 1-513/513
Sequence Identity: 20% (104 aa)

YTIMAKVGDGTFSNVFKVKK--------------NSTGEIFAMKVMKKHYESVEEVD-----------ANDEIRYMRELG----------------EHQN
|.|. |.| ||...|.| .               . |.|| |.| .|.     |.             |..||.....|                  | |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

ILQLYDVIFEPK---------------LGRLSLVTDLMEFNLLNLLNTPHF---------FPDDV-------------LYYS------YQLLNGLS--YL
|..|||..  ..               .  | ||...|. .|....   .|         ... .              |..      ||.|.||   |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSAG--FVHRDIKPENILINLRSRE-------------------LRIGDFGSLVEEPCNYIP----------------------GEYITTRWYRAPELLL
||..  ..|||.|||||||| . .                    |.|.|||.   .  .  .                       .|. ||||||||.||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

KCPTYN---------CAIDVWSVGCVIAEMILK--------HPLFP-----------GGDTTSQLEMIHNALGAPT---------------AE-------
 .. |.         ..||.|||||..|||...        .||||           | ..  ||..| . || ||                |       
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

------------------LFETMAADSRYKAEDFQNVTPISLINRLEV----------------------------------CPYTDLVALVMTMLKYNP
                   .   |   . .  .|... |... |                                      |   ... |.. ||.|.|
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

SDRVDSGTAAASTVF
..|     | .   |
DKRITAEQALQHPYF

Kinase 94984.m00243.AA RCK 11-282 32 2.5e-74 235.2 In-house 1-286 (298) Show / Hide
Range on Protein: 11-282
Range on HMM: 1-286/298
Sequence Identity: 32% (94 aa)

YTIMAKVGDGTFSNVFKVKKNSTGEIFAMKVMKKHYESVEEVDANDEIRYMRELGEHQNILQLYDVIFEPKLGRLSLVTDLMEFNLLNLLNT----PHFF
|.|....||||.. |.| ..  |||| |.| ||....| ||.    ||. .| |  | ||..|..||.. . ..|..|  .|. ||  .. .     . .
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKYL

PDDV---LYYSYQLLNGLSYLHSAGFVHRDIKPENILINLR--------SRELRIGDFGSL--VEEPCNYIPGEYITTRWYRAPELLLKCPTYNCAIDVW
|  .     . ||.| ||...|. || |||.|||||...          .  . |.|||.   ..   .|   .|..||||||||.||.| .||  .|.|
PENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPY--TDYVSTRWYRAPECLLRCTYYNSPMDIW

SVGCVIAEMILKHPLFPGGDTTSQLEMIHNALGAPTAELFETMAADSRYKAEDFQNVTPISLINRLEVCPYTDLVALVMTMLKYNPSDR
.|||...|   ..||||| .   |.  |.. .| |. .  .     .. .  .|... ...|   .  |.. |.. |.. ||...|. |
AVGCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPNCSQ-DCIELMEKMLQWDPQKR

Kinase 94984.m00243.AA S_TKc 11-294 24 7.2e-72 246.0 SMART 1-231 (231) Show / Hide
Range on Protein: 11-294
Range on HMM: 1-231/231
Sequence Identity: 24% (75 aa)

YTIMAKVGDGTFSNVFKVKKNSTGEIFAMKVMKKHYESVEEVDANDEIRYMRELGEHQNILQLYDVIFEPKLGRLSLVTDLMEF---NLLNLLNTPHF--
|.|. |.| |.|. |.|.....||.|.|.|..|         ..  ||. ...   | || .||||. .   ..| .|.....    .|. ..       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FPDDVLYYSYQLLNGLSYLHSAGFVHRDIKPENILINLRSRELRIGDFGSLVEEPCNYIPGEYITTRWYRAPELLLKCPTYNC-AIDVWSVGCVIA
    || .. .| ||....| |.|| |..|||.||||||..    .. |.|||.  .         .. |.||.|||.|     |.. ..|.||.||...
LRFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILY

EMILKHPLFPGGDTTSQLEMIHNALGAPTAELFETMAADSRYKAEDFQNVTPISLINRLEVCPYTDLVALVMTMLKYNPSDRVDSGTAAA-------STV
||.   |.||      |..|. . .|                                       ..  ... .|...|..|     | .          
EMLCGYPPFP------QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPW

F
|
F

Kinase 94984.m00243.AA MOK 11-294 37 8.4e-70 217.79 In-house 1-283 (283) Show / Hide
Range on Protein: 11-294
Range on HMM: 1-283/283
Sequence Identity: 37% (108 aa)

YTIMAKVGDGTFSNVFKVKKNSTGEIFAMKVMKKHYESVEEVDANDEIRYMRELGEHQNILQLYDVIFEPKLGRLSLVTDLMEFNLLNLLNT-PHFFPDD
|  . |.|.||||.| |..    |. .| | ||.|.||.|.|..  ||  || |  | |||.| .|.|. | | |.|. .||. |.  |.    |. |..
YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNNLREIQAMRRLNPHPNILMLHEVVFDRKTGNLALICELMDMNIYELIRGRRHYLPQK

-VLYYSYQLLNGLSYLHSAGFVHRDIKPENILINLRSRELRIGDFGSLVEEPCNYIPGEYITTRWYRAPELLLKCPTYNCAIDVWSVGCVIAEMILKHPL
 .  | |||.  |  .|  |  |||.|||||||  .   |...||||           ||| |||||||| ||    |   .|.||||||  |..  |||
KIMHYMYQLCKSLDHMHRNGIFHRDVKPENILI--KQDHLKLADFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGYYTYQMDMWSVGCVFYEIASLHPL

FPGGDTTSQLEMIHNALGAPTAELFETMAADSRYKAEDFQNVTPISLINRLEVCPYTDLVALVMTMLKYNPSDRVDSGTAAASTVF
|||     |.  ||  .| | ... .     ||    ||      | |..|        . ..  |  | | .|.    .     |
FPGVNEVDQISKIHDVMGTPCQKILNKFKNQSRAMNYDFP-FKKGSGIEKLTPNLTKQCLEIMHKMCTYDPDERITAHQVIQHPYF

Kinase 94984.m00243.AA CDC2 11-211 35 1.9e-59 181.16 In-house 1-211 (301) Show / Hide
Range on Protein: 11-211
Range on HMM: 1-211/301
Sequence Identity: 35% (77 aa)

YTIMAKVGDGTFSNVFKVKKNSTGEIFAMKVMKKHYESVEE---VDANDEIRYMRELGEHQNILQLYDVIFEPKLGRLSLVTDLMEFNLLNLLN--TP--
|.   |.| ||.  |.| | . |..| |.|  .  .|. ..     |  || .. || .|.|| .| |||..    .| .|.. ....| ...    |  
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN

-HFFPDDVLYYSYQLLNGLSYLHSAGFVHRDIKPENILINLRSRELRIGDFG--SLVEEPCNYIPGE-YITTRWYRAPELLLKCPTYNCAIDVWSVGCVI
 |. |. |  | ||.|.|....|. . .|||.|| ||||.   . ..|.|||    .  | . .  |  . |.||||||.|| | .|....|.||.||..
KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIF

AEM---ILKHPLFPG
|||   . |.|||.|
AEMFMDVTKKPLFHG

Kinase 94984.m00243.AA Pkinase 11-229 32 1.1e-58 206.14 Pfam 1-235 (293) Show / Hide
Range on Protein: 11-229
Range on HMM: 1-235/293
Sequence Identity: 32% (78 aa)

YTIMAKVGDGTFSNVFKVKKNSTGEIFAMKVMKKHYESVEEVDAN---DEIRYMRELGEHQNILQLYDVIFEPKLGRLSLVTDLMEF-----NLLNLLN-
|.|  |.| |.|. |.| .. .||.|.|.|..||. |. ..  ..    ||..|..|  | ||..|||.  .   ... .|....|       |  ..  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

--TPHF--FPDDVLYYSYQLLNGLSYLHSAGFVHRDIKPENILINLRSREL----RIGDFGSLVE--EPCNYIPGEYITTRWYRAPELLLKCPTYNCAID
     |   ....  | ||.| || |.|| |..|||.|||||||. .  ..    .|.|||.     .  |  .  .  |.||.|||...... |  ..|
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VWSVGCVIAEMILKHPLFPGG----DTTSQLEMIHNALGAPT
.||.||...||....|.|||     .  .|..|| . .|.|.
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPL

Kinase 94984.m00243.AA MAPK 57-243 33 1.5e-53 183.5 In-house 54-270 (328) Show / Hide
Range on Protein: 57-243
Range on HMM: 54-270/328
Sequence Identity: 33% (74 aa)

EIRYMRELGEHQNILQLYDVIFE------PKL---GRLSLVTDLMEFNLLNLLNTPH-FFPDDVLYYSYQLLNG--LSYLHSAGFVHRDIKPENILINLR
||. .|....| ||  |.|..        . |     . .|..||| .| ......     | . |  ||.|.|  | |.|||. .|||.||.|||.|  
EIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMETDLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNEN

SRELRIGDFG-SLVEEP-CNYIPG-------------EYITTRWYRAPELLLK--CPTYNCAIDVWSVGCVIAEMIL-KHPLFPGGDTTSQLEMIHNALG
  .|.|.||| . ...|  ... .             ||..||||||||..|      |. |.|.|||||  |||.   .||||| |.  |...| . ||
C-DLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLG

APTAELFETMA-ADSRYK
 |. |. . .   .. ..
TPSEEFIQCICMSEHARN

Kinase 94984.m00243.AA p38 11-240 35 1.1e-49 167.88 In-house 1-235 (289) Show / Hide
Range on Protein: 11-240
Range on HMM: 1-235/289
Sequence Identity: 35% (86 aa)

YTIMAKVGDGTFSNVFKVKKNSTGEI---FAMKVMKKHYESVEEVDAND---EIRYMRELGEHQNILQLYDVIFEP------KLGRLSLVTDLMEFNLLN
|  .  || | . .| |.    ||.    .|.| . . ..|  |..|     |.|  . . .| |...| || | |       .    .|| .|.  | |
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQS--EIHAKRTYRELRLLKHM-RHENVICLLDV-FTPPAHSMNDFQDVYMVTHFMGADLNN

LLNTPHFFPDDVLYYSYQLLNGLSYLHSAGFVHRDIKPENILINLRSRELRIGDFGSLVEEPCNYIPGEYITTRWYRAPELLLKCPTYNCAIDVWSVGCV
.. . ..  | . .  ||.| || | |||| .||| || || .| .. |||| ||| |   .|     .|. |||||||| .|    |. ..|.|||||.
IMKCQRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDC-ELRILDFG-LAR-HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCI

IAEMILKHPLFPGGDTTSQLEMIHNALGAPTAELFETMAADS
.||.|   .|||| |  .||. | . .| |..|. . .. ..
MAELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEE

Kinase 94984.m00243.AA ERK7 11-294 29 3.1e-46 155.98 In-house 1-292 (292) Show / Hide
Range on Protein: 11-294
Range on HMM: 1-292/292
Sequence Identity: 29% (87 aa)

YTIMAKVGDGTFSNVFKVKKNSTGEIFAMKVMKKHYESVEEVDAN---DEIRYMRELGEHQNILQLYDVIFEPKLGRLSLVTDLMEFNLLNLLNTPHFFP
| |  ..| | .  | |.    |... |.| .   .   ...||     || ...|...| ||..|..||       . || . ||  | .     .   
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFR--NQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIRKGNILK

D-DVLYYSYQLLNGLSYLHSAGFVHRDIKPENILINLRSRELRIGDFG---SLVEEP----CNYIPGEYITTRWYRAPELLLKCPTYNCAIDVWSVGCVI
|  . |  ||||. . |.||.  .|||.|| |||..   . ... |||   |. . .     | .  ||. |||||||| ||   .|  ..| ||.||..
DIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECM-VKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCIL

AEMILKHPLFPGGDTTSQLEMIHNALGAPTAELFETMAADSRYKAEDFQNVTPISLINRLEVCPYTDLVALVMTMLKYNPSDRVDSGTAAASTVF
.||. . |.|||  |  |.| | . .. ||.|  | .  . . .  .  |...   .. .     .| . |.  .| .||  |..   | .    
GEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV

Kinase 94984.m00243.AA GSK 168-282 33 1.3e-38 115.16 In-house 178-316 (328) Show / Hide
Range on Protein: 168-282
Range on HMM: 178-316/328
Sequence Identity: 33% (47 aa)

YITTRWYRAPELLLKCPTYNCAIDVWSVGCVIAEMILKHPLFPGGDTTSQLEMIHNALGAPTAELFETMAADS-RYKAE--DFQNVTPISLIN-------
|| .| ||||||...|  |.|.|||||.|||.|||.. .||||| ..  ||. | ..|| ||.| .. |  .. ..| .   ||...|...         
YICSRYYRAPELIFGCTNYTCQIDVWSCGCVMAEMLKGQPLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKPHPWQKNDTKYEY

------------RLEVCPYTD--LVALVMTMLKYNPSDR
             ...|.  .  .. |.. .|.|.|. |
QTYYHKKYRTVYMFKWCHTDMQDWIDLISKCLVYDPKKR

Kinase 94984.m00243.AA CDK 11-154 31 3.6e-36 113.11 In-house 1-158 (284) Show / Hide
Range on Protein: 11-154
Range on HMM: 1-158/284
Sequence Identity: 31% (53 aa)

YTIMAKVGDGTFSNVFKVKKNSTG-----EIFAMKVMKKHYE-SVEEVDAND-----EIRYMRELGEHQNILQLYDVIFEPKLG---------RLSLVTD
| . .|.| ||.  |.| .   ||     .| |.|  .   |   || .        || ...||  |.|| .|.||.   ..          .|..| .
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

LMEFNLLNLLNTPHFFPDDVLYYSYQLLNGLSYLHSAGFVHRDIKPENILINLRSR----ELRIGDFG
 |.  |  ..         .  | .|||.||.|.|| ...|||.|| ||||| .       | |.|||
YMDHDLKKYMD--------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFG

Kinase 94984.m00243.AA GSK 11-155 30 5.4e-34 100.78 In-house 1-163 (328) Show / Hide
Range on Protein: 11-155
Range on HMM: 1-163/328
Sequence Identity: 30% (52 aa)

YTIMAKVGDGTFSNVFKVKKN----STGEI----FAMK-VMKKHYESVEEVDANDEIRYMRELG--EHQNILQL---YDVIFEP----KLGRLSLVTDLM
|..| ..| |.|..|.. . |     |.||    .| | | ...        .| |   |..||   |.|| .|   ..   |     ..  ..|| . |
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYK-----CNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLVMEYM

EFNLLNLLNT-----PHFFPDDVLYYSYQLLNGLSYLHSAGFVHRDIKPENILINLRSRELRIGDFGS
. .| ....        .   .. .|.||.. ||.|||| | .||||||.|||.. .. .| | ||||
PQTLYQVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVLKICDFGS

Kinase 94984.m00243.AA CDK 171-294 31 2.4e-31 97.39 In-house 182-284 (284) Show / Hide
Range on Protein: 171-294
Range on HMM: 182-284/284
Sequence Identity: 31% (41 aa)

TRWYRAPELLLKCPTYN--CAIDVWSVGCVIAEMIL---KHPLFPGGDTTSQLEMIHNALGAPTAELFETMAADSRYKAEDFQNVTPISLINRLEVCPYT
|.||||||||| . .|.  ..||.|||||..|||..   . |||||   . ||..| . .| || .    .     |                       
TLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-----------------------

DLVALVMTMLKYNPSDRVDSGTAAASTVF
    | . || |.|. |. .  |  .  |
---DLLNKMLCYDPKKRISAEQALQHPYF

Kinase 94984.m00243.AA CDK5 171-294 28 1e-26 81.06 In-house 161-287 (287) Show / Hide
Range on Protein: 171-294
Range on HMM: 161-287/287
Sequence Identity: 28% (37 aa)

TRWYRAPELLLKCPTYNCAIDVWSVGCVIAEMI-LKHPLFPGGDTTSQLEMIHNALGAPTAELFETMAADSRYK--AEDFQNVTPIS-LINRLEVCPYTD
| |||.|  |.   .|.  ||.||.||..|||.    ||||| |.. ||  |   .| |. .    ..  . ||  ....    .   . .         
TLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPK-LDEK

LVALVMTMLKYNPSDRVDSGTAAASTVF
.  |   ||..||  |..   |     |
GMDLLQKMLQCNPNQRISAKAALHHPYF

Kinase 94984.m00243.AA CDK5 11-154 35 1e-24 74.64 In-house 1-143 (287) Show / Hide
Range on Protein: 11-154
Range on HMM: 1-143/287
Sequence Identity: 35% (53 aa)

YTIMAKVGDGTFSNVFKVKKNSTGEIFAMKVMKKHYE-SVEEVDANDEIRYMRELGEHQNILQLYDVIFEPKLGRLSLVTDLMEFNL---LNLLNTPHFF
|  | |.|.||.  |.| .   |.||.|.|  .   |       |  ||  ..||  |.||  |.|||   |  .| ||   .   |   .. .|     
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKEL-KHKNIVRLHDVIHSEK--KLTLVFEFCDQDLKKYMDSCNG-EMD

PDDVLYYSYQLLNGLSYLHSAGFVHRDIKPENILINLRSRELRIGDFG
.. . .. |||| ||.. |.    ||| || | ||| .  ||. .|||
MHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNG-ELKLADFG

Kinase 94984.m00243.AA TyrKc 11-294 21 1.4e-12 -19.38 SMART 1-280 (280) Show / Hide
Range on Protein: 11-294
Range on HMM: 1-280/280
Sequence Identity: 21% (69 aa)

YTIMAKVGDGTFSNVFKVKKNSTGEIFAMKVMKKHYESVEEVDANDEIRYMRELG-EHQNILQLYDVIFEP-----KLGRLSLVTDLMEF-NLLNLLNTP
 |   | | | |  |.| . .   .  | |..|..     . |  .|.| |..|| .|.||..|| |. ..       . | .|. .|.  .|.. |  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

H--FFPDDVLYYSYQLLNGLSYLHSAGFVHRDIKPENILINLRSRELRIGDFG-SLVEEPC-------NYIP------GEY-ITTRWYRAPELLLKCPTY
.  . ..| |....|  .| .|||| ...|||.   |.|.. .    .|.||| |   .          |.       | . .  ||. ||| . .. ..
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECINYG-KF

NCAIDVWSVGCVIAEMI-LKHPLFPG-----GDTTSQLEMIHNA--LGAPTAELFETMAADSRYKAEDFQNVTPISLINRLEVCPYTDLVALVMTMLKYN
. . |||| | .. |.  .  .  ||      . .  .| . .   .  |   . . |.                       ||  ...  .  .  ...
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MS---------------------F-VCCPDEMYQIMKQCWHED

PSDRVDSGTAAASTVF
|.||    .      |
PEDRPTFSEI--HECF

Kinase 94984.m00243.AA Pkinase_Tyr 11-134 28 1.8e-12 42.84 Pfam 1-137 (270) Show / Hide
Range on Protein: 11-134
Range on HMM: 1-137/270
Sequence Identity: 28% (39 aa)

YTIMAKVGDGTFSNVFKVKKN----STGEIFAMKVMKKHYESVE--EVDANDEIRYMRELGEHQNILQLYDVIF---EPKLGRLSLVTDLMEF-NLLNLL
 |.. | | | | .|.| . .    .|.   | |..| .. . .    |   |.. |..|| |.||..|| |.    ||.  .. .|. .|.  .||. |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLDYL

NTP-----HFFPDDVLYYSYQLLNGLSYLHSAGFVHRDI
 ..     .. . | | ...|  .|..||.| ...|||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL

Kinase 94984.m00243.AA MAPK 11-44 20 0.006979 5.54 In-house 1-40 (328) Show / Hide
Range on Protein: 11-44
Range on HMM: 1-40/328
Sequence Identity: 20% (8 aa)

YTIMAKVGDGTFSNVFKVKKNS------TGEIFAMKVMKK
|.|  ..| | .  |.... ..      .|.. | | . .
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISR

Kinase 94984.m00243.AA CDC2 270-294 36 0.021612 2.57 In-house 277-301 (301) Show / Hide
Range on Protein: 270-294
Range on HMM: 277-301/301
Sequence Identity: 36% (9 aa)

LVMTMLKYNPSDRVDSGTAAASTVF
| | || |.|..|. . .| .   |
LLMQMLQYDPQKRISAKEALQHPYF