Gene 85889.m00376 (T.vaginalis)

85889.m00376

Species: T.vaginalis
Alias: TvagK0050, 85889.m00376
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
85889.m00376.AA Protein None 516 None Fasta, JSON
85889.m00376.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 85889.m00376.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85889.m00376.AA AGC 13-266 24 7.9e-89 229.07 In-house 1-395 (395) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-395/395
Sequence Identity: 24% (96 aa)

YTILKLTGRGAFSSVYQAVHN------DTGIKVALKVVLASS-LQEPM--QRAMVENE------------INVFKLID----------YPLVVE-FYEAF
. .||. |.|.|. ||.. ..      |||   |.||.  .   .. .  . ... .|             |......           | .|   . .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

FDKEY--FVVALEFVE---------GG-SILSYIN---KFGKLTEDEARHYFCQ-------LVQTLEYLNSRCRIAHRD-LKAENVLIDENHNIRLIDFG
 ||..      .|...         ||   ....    | |...|..||.|...       .|  |||| |   | ||| || ||.|.||. .|.| |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FSHIMSN--------------------------------------------------KIPVINGPCG--SPAYAPPEVLKNQPFTHLSDVWS--AGVFLY
.. .. |                                                  |    .  ||  .| | .||.|     ..  | ||   |...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

GITTGNLPFVDDNIQ----------RLMQKIV------YTEPKFN----------SNVSPELKDLIMKLLKKTPSQRLS----------LHEIWSHPWI
   ||  || .|| |           ..|||         ..||.          ...|||.|||| |||.| |..||             || .||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
S_TKc 85889.m00376.AA S_TKc 13-266 32 2.4e-88 300.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-231/231
Sequence Identity: 32% (89 aa)

YTILKLTGRGAFSSVYQAVHNDTGIKVALKVVLASSLQEPMQRAMVENEINVFKLIDYPLVVEFYEAFFDKEYFVVALEFVEG--GSILSYINKFGK---
|.||.. |.|||..||...|..|| .||.|..            ....||.. |  . | .| .|..| | ... . .|...|  |. ..|| | |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTEDEARHYFCQLVQTLEYLNSRCRIAHRDLKAENVLIDENHNIRLIDFGFSHIMSNKIPVINGPCGSPAYAPPEVLKNQPFTH-LSDVWSAGVFLY
   ..| .||.|..|... |||. |. .| ||||| ||.|.||  .| ..|||.. ..       .  ||.| | .||||   ....  .|.|| |. ||
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

GITTGNLPFVDDNIQRLMQKIVYTEPKFNSNVSPELKDLIMKLLKKTPSQRLSLHEIWS-------HPWI
   .|  ||   ..|....||.          |||.||.|.|.|.| |..|..  |.         |||.
EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 85889.m00376.AA CAMK 18-266 22 2.3e-85 274.95 In-house 1-425 (425) Show / Hide 
Range on Protein: 18-266
Range on HMM: 1-425/425
Sequence Identity: 22% (96 aa)

LTGRGAFSSVYQAVHNDTG------------IKVALKVVLASSLQE-------------------------PMQRAMVENEINVFKL-------IDYPLV
  |||.|. |. ..|  |.             ||| |..  . |..                         |  |..|..||.. |.       .| | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VEFYEAFFD-------------------KEYFVVAL---EFVEGG----SILSYINKF---------------GKLTEDEARHYFCQLVQTLEYLNSRCR
. .||.. |                   .....  .   |...||     ...|| .                |..||.|||.|| |... ..|. |.  
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-

IAHRDLKAENVLIDENH-----------------NIRLIDFGFSHIMSNKI-----------------------PVINGPCGSPAYAP-PEVLKN-----
|.||||| ||.|.|.|.                 || .|||||. ..  .                        .  . .||.|.|.. ||||.      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------QPFTHLSDVWSAGVFLYGITTGNLPFVDD-------------NIQRLMQKIV---YT-EPKFNSNVS--------------------PELK
         .. .  .|.||.|| ||   .| .|| .|             |...|..||    |. .|.. |..|                    .| |
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLIMKLLKKTPSQRLSLHEIWSHPWI
||| |.|.. |..|...... .|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 85889.m00376.AA CAMKL 13-266 33 5.1e-84 268.01 In-house 1-297 (297) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-297/297
Sequence Identity: 33% (100 aa)

YTILKLTGRGAFSSVYQAVH-NDTGIKVALKVVLASSLQ-EPMQRAM-----------VENEINVFKLID---YPLVVEFYEAFFDKEY------FVVAL
|.|.|  |.|.|. |  |.|   ||.||| |..  . .. .|  ...           .. ||.  |...    | .. .|| . ..|.      ..  .
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFVEGGS--ILSYINKF----GKLTEDEARHYFCQLVQTLEYLNSRCRIAHRDLKAENVLIDENH--NIRLIDFGFSHIMSN--KIPVI--NGPCGSPAY
| ..||.   . || |     |...|.|||.||.|.|  ..|. |.. |.|||.|.||.|.|||.  || .|||||| .. .  ..|    .  ||||.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

APPEVLKN--QPFT-HLSDVWSAGVFLYGITTGNLPFVDD--------NIQRLMQKIVYTEPKFN--SNVSPELKDLIMKLLKKTPSQRLSLHEIWSHPW
..||...   .|.     |.||.|| || . .|.||| ||        || .|. ||  .  ...  . || ...||| |.|.. |..| ..|.| .|||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

I
 
M
Kinase 85889.m00376.AA MARK 13-266 35 8.3e-80 260.56 In-house 1-262 (262) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-262/262
Sequence Identity: 35% (95 aa)

YTILKLTGRGAFSSVYQAVHNDTGIKVALKVVLASSLQEPMQRAMVENEINVFKLIDYPLVVEFYEAFF--DKEY-FVVALEFVEGGSILSYINKF--GK
| .||  | |... |. |.|  ||.|||.|..   .|..| .. .|. ||.. |..| | ........   ...  ... .| ..||. ..|| ..  |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LTEDEARHYFCQLVQTLEYLNSRCRIAHRDLKAENVLIDENH--NIRLIDFGFSHIMSNKIPVINGPCGSPAYAPPEVLKNQPFT-HLSDVWSAGVFLYG
|.|.|||..| |.|  ..|. |.  |.|||.|.||.|||||   || .|||||| |  .     |  ||.|.|..||... .| .    |.|| || || 
LHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFS-ICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYF

ITTGNLPFVDDN--IQRLMQKIVYTEPKFNSNVSPELKDLIMKLLKKTPSQRLSLHEIWSHPWI
...|..|| .|.  .  |..||.  .... ..||.|...|| .||.  |..| ...|| .|||.
MVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 85889.m00376.AA Pkinase 13-266 28 1.4e-75 262.22 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-293/293
Sequence Identity: 28% (84 aa)

YTILKLTGRGAFSSVYQAVHNDTGIKVALKVVLASSLQEPMQRAMVE-NEINVFKLIDYPLVVEFYEAFFDKEYFVVALEFVEGG----SILSYIN--KF
|.|..  |.|.|..||...| .||..||.|..  ..  . .... .  .|| . | .. | .|..|..| || .  . .|..|||    .  .||   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKL--TEDEARHYFCQLVQTLEYLNSRCRIAHRDLKAENVLIDENHNI----RLIDFGFSHIM-SNKIPVINGPCGSPAYAPPEVLK-NQPFTHLSDVWS
|..  .|.|...|. |... |||. | ..| ||||| ||.|||.| .|    ...|||..  .   . .  ...||.| |..|||.. .|. .. .|.||
GCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

AGVFLYGITTGNLPFVDD------NIQRLMQKIVYTEPKFNSNVS---------------------PELKDLIMKLLKKTPSQRLSLHEIWSHPWI
.|. ||   .|..|| ..      . . ....| .....|..  .                     .|.||.| ..|.| |..|.. ..|  |||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 85889.m00376.AA AMPK 13-266 38 1.3e-74 220.96 In-house 1-254 (254) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-254/254
Sequence Identity: 38% (98 aa)

YTILKLTGRGAFSSVYQAVHNDTGIKVALKVVLASSLQEPMQRAMVENEINVFKLIDYPLVVEFYEAF--FDKEYFVVALEFVEGGSILSYINKFGKLTE
| | |  |.|.|  |  ..|  || |||.|.     ...      ...||   ||.  | ..  ||      .. |.| .|.| ||   .|| | |.|.|
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMV-MEYVSGGELFDYIVKHGRLQE

DEARHYFCQLVQTLEYLNSRCRIAHRDLKAENVLIDENHNIRLIDFGFSHIMSNKIPVINGPCGSPAYAPPEVLKNQPFTHLS-DVWSAGVFLYGITTGN
.||. .| | .  .||. .|  |.||||| ||.|.|.|.|| . ||| | .|.         |||| || ||.  ...   .  |.|| || ||    | 
REACRFFQQIISGVEYC-HRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDG-EFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGY

LPFVDDNIQRLMQKIVYTEPKFNSNVSPELKDLIMKLLKKTPSQRLSLHEIWSHPWI
||| |.|.  | .||.  |..  ...||| ||||...|.. | .|.. |.|  ||| 
LPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 85889.m00376.AA Ciliate-E2 13-266 22 1.7e-69 237.16 In-house 1-365 (365) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-365/365
Sequence Identity: 22% (85 aa)

YTILKLTGRGAFSSVYQAVHNDTGIKVALKV-----------------VLASSLQEPMQRAMVENEINVFK----------------LIDYPLVVEFYEA
| ..|. |.|.|.|||.. .  .. ..|.|.                   |   ... |  ....||....                ... | ....||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FF--DKEYFVVALEFVEGGSILSYINKF-----------GKLTEDEARHYFCQLVQ---------------TLEYLNSRCRIAHRDLKAENVLIDENHNI
|   |....   .|...||. ..||...           ...|| |..... |..|                |||| |. .| |||.| ||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RLIDFGFSHIMSNK----------IPVINGP----------------------CGSPAYAPPEVLKNQP---------FTHLSDVWSAGVFLYGITTGNL
 .||||.| . ...             ..                        ||.| | .||.|....          .. .|.||.|| ||   .|..
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFVDDNIQRLMQ-KIVYTEPKFN-------------SNVSPELKDLIMK----LLKKTPSQRLS-LHEIWSHPWI
||    .|  .| || . .|...              ..|.| |||| |    .|.| |..|..   .|  |||.
PF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 85889.m00376.AA Ciliate-E2-Unclassified 13-266 26 1.6e-68 233.95 In-house 1-352 (352) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-352/352
Sequence Identity: 26% (94 aa)

YTILKLTGRGAFSSVYQAVHNDTGIKV------ALKVVLASSLQEPMQRAMVENEINVFKL------------------IDYPLVVEFYEAFFDKEYFVV
|.|.|  |.|.|..||...|.... ..        . . .. ... ..  .. ... ....                  .. |..| ....| ||...  
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

ALEFVEGGSILSYINKFGK-----------------LTEDEAR-----HYFCQLVQTLEYLNSRCRIAHRDLKAENVLIDENH---NIRLIDFGFS-HIM
 .|..|||. . ||.|..|                 .|| .|.     .|| |..| |||| .   | |||.| ||.|.|.|.   .|..||||.| .. 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

SN--------------KIPVINGPCGSPAYA----PPEVLKNQPFT----HLSDVWSAGVFLYGITTGNLPFVDDNIQR----------------LMQKI
.|              |   ..  ||.| |     .||||..|       . .|.|| || || . .|..|| | |                   | |.|
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

V---YTEPKFNS-----NVSPELKDLIM----KLLKKTPSQRLSLHEIWSHPWI
    .  |||.      ..||| ||.|     |.||| |..|... .|  |||.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 85889.m00376.AA ULK 13-266 23 5.5e-62 212.25 In-house 1-329 (329) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-329/329
Sequence Identity: 23% (78 aa)

YTILKLTGRGAFSSVYQAVHNDT----GIKVALKVVLASSLQEPMQRA-------MVENEINVFKLIDYPL--------VVEFYEAFFDK--EYFVVALE
| . .  | |.|  ||.. ...|    ..||| |... .....  . .       ...||| . | .. |         .|..|. | ..   ..   .|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FVEGGSILSYINKFGK----------LTEDEARHYFCQLVQTLEYLNSRCRIAHRDLKAENVLIDENHN------------IRLIDFGFSHIMSNK---I
. .||   .||.| .|          |.|.||...|.|... . .|... .| |||.| .|.||...              . . ||||.  ..|    .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKH-NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

PVINGPC------GSPAYAPPEVLK----NQPFT-HLSDVWSAGVFLYGITTGNLP----FVDDNIQRLMQKIVY----------TEPKFN-----SNVS
 ..          |.| |  |..|.    ..|.. . .|.|| |. .| . .|  |    | |...| ... | .          . ..|.      ..|
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PELKDLIMKLLKKTPSQRLSLHEIWSHPWI
||.|||| ..|.. ...| | .|. .|||.
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 85889.m00376.AA BRSK 13-266 38 1.4e-60 205.14 In-house 1-254 (254) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-254/254
Sequence Identity: 38% (101 aa)

YTILKLTGRGAFSSVYQAVHNDTGIKVALKVVLASSLQ-EPMQRAMVENEINVFKLIDYPLVVEFYEAFFDKEYFVVALEFVEGGSILSYINKFGKLTED
| . |  |.|    |   || .|| ||| |..    |   .  .  || || . |||| | | . |. .  | |    ||.|.||    |  | |.||  
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

EARHYFCQLVQTLEYLNSRCRIAHRDLKAENVLIDENHNIRLIDFGFSHIMSNKIPVINGPCGSPAYAPPEVLKNQPF-THLSDVWSAGVFLYGITTGNL
||| .| | .  |..  |.  | ||||| || | ||  ||.  |||   .  .        |||| || ||| .   .     ||||.|| ||   .| |
EARKFFRQIISALDFCHSHN-ICHRDLKPENLLLDEKNNIKIADFGMASLQVKDM-MLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGAL

PFVDDNIQRLMQKI---VYTEPKFNSNVSPELKDLIMKLLKKTPSQRLSLHEIWSHPWI
|| |||. .|. |.   |.  | |   . |   ||  ...   |..|.||.||  ||| 
PFDDDNLRQLLEKVKRGVFHMPHF---IHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase 85889.m00376.AA AktR 13-266 32 1.3e-59 204.4 In-house 1-268 (268) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-268/268
Sequence Identity: 32% (87 aa)

YTILKLTGRGAFSSVYQAVHN-DTGIKVALKVVLASSLQEPMQRAMVENEINVFK-LIDYPLVVEFYEAFFDKEYFVVALEFVEGGSILSYINKFGKLTE
....|. |.|||. || . .. |.. ..|.|..  . ..|  |.  . .| |. . ... |  | ....| .||.   ..|...|| ......| .|..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DEARHYFCQLVQTLEYLNSRCRIAHRDLKAENVLIDENHNIRLIDFGFSH--IMSNKIPVINGPCGSPAYAPPEVLKN-QPFTHLSDVWSAGVFLYGITT
..|| ||.| .  |||| ..  |  |||| || |.||. .....||| |   .|  . .. .  ||.|.| .||.... .. .  .| |. |.|.| . |
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GNLPFVDDNIQRLMQKIVYTE---PKFNSNVSPELKDLIM-KLLKKTPSQRLS-----LHEIWSHPWI
|. || ..| ... ||| . .   ....|..|...||||  |||.| | .||        || |||| 
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 85889.m00376.AA TyrKc 13-266 22 2.6e-15 24.96 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

YTILKLTGRGAFSSVYQAVHNDTGIKVALKVVLASSLQEPMQRAMVENEINVFKLI--DYPLVVEFYEAFFDK-------EYFVVALEFVEGGSILSYIN
 | .|  |.|||  ||... .   |.|| |.. ...      |..  .|... . .  . | .| .| .  ..       |   . .|....|. ..|. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KFGK-LTEDEARHYFCQLVQTLEYLNSRCRIAHRDLKAENVLIDENHNIRLIDFGFSHIMSNK--------IPVING--PCG--SP-AYAPPEVLKNQPF
| .. |. ..  ..  |  .  ||| |. .. |||| | |.|..||| ..  ||| |    ..          .  .   .    |    .||...   |
KHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

THLSDVWSAGVFLYGITT-GNLPFVD-----DNIQRLMQKIV--YTEPKFNSN-------VSPELKDLIMKLLKKTPSQRLSLHEIWSHPWI
|. ||||| || .. | | |  |  .      . |......   |  |.  ..        ..|. ... .  .  |..| .  ||  |  .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 85889.m00376.AA Pkinase_Tyr 13-157 27 1.4e-11 39.82 Pfam 1-156 (270) Show / Hide 
Range on Protein: 13-157
Range on HMM: 1-156/270
Sequence Identity: 27% (43 aa)

YTILKLTGRGAFSSVYQAVHN----DTGIKVALKVVLASSLQEPM--QRAMVENEINVFKLI-DYPLVVEFYEAFF-DKEY--FVVALEFVEGGSILSYI
 |..|  |.||| .||... .    .|.|.|| |..   .  ..   .... . |... | . . | .| .| .   ..|     . .|....|. |.| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

NK----FGKLTEDEARHYFCQLVQTLEYLNSRCRIAHRDLKAENVLIDENHNIRLIDFG
 |     ..||  .  ..  |  . .||| |.  . |||| | |.|..||. ..  |||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN-CIHRDLAARNCLVTENNVVKICDFG
Kinase 85889.m00376.AA Pkinase_Tyr 180-203 45 0.002267 12.04 Pfam 182-205 (270) Show / Hide 
Range on Protein: 180-203
Range on HMM: 182-205/270
Sequence Identity: 45% (11 aa)

PPEVLKNQPFTHLSDVWSAGVFLY
.||....  ||. ||||| || ..
APECINYGKFTTKSDVWSFGVLMW