89397.m00103

Species: T.vaginalis
Alias: TvagK0720, 89397.m00103
External Links:
Annotation:

Classification

Group: CMGC
Family: CK2

Sequence

Name Sequence Type Origin Length Description Download
89397.m00103.AA Protein None 343 None Fasta, JSON
89397.m00103.kin_dom Protein Kinase Domain None 283 None Fasta, JSON

Protein domain

Protein domains of 89397.m00103.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 89397.m00103.AA CK2 50-332 33 5.1e-91 271.9 In-house 1-288 (288) Show / Hide
Range on Protein: 50-332
Range on HMM: 1-288/288
Sequence Identity: 33% (97 aa)

YSIGSILGSGKFSTVFKGTDGKHVYAM----KVYKDVRPNYIRREIFMHKALRKCEHIVQLHDVVRDPVSKSTTLLLEYHKSGNWKNFFPKMKISDIKNF
| ... .|.||.| ||.| . |    .    |. | |.   |.|||   . |.  . |..| |.|.||.|| . |. || .   ... .....  ||. .
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY

MYKLLLALDECHSHGIMHRDVKQQNILYNPKTGDLHLGDLGLAEVYFPYHQYEVGIGTIRFMAPEILMSYRFYNYAIDIWSAGVILAEMI-HEEPLFKGD
|..||.||| ||| |||||||| .||. ...   | | | |||| |.|...| | ...  . .|| |. |. | |..|.|| |...| || . ||.|.|.
MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGH

YQLDILRSISRVFTASPLLEFADKIGFEVSTNLLNALSSISIGQFDAILSRVRDEYKDDDLFDLLRLMLVIDPTYRITARDALNHKFF
   | |  | .|.  . |... || | ..  .  . . . .. ..     .  ... ...  |.|  ||..|.. ||||..|..|..|
DNYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQFHDIMQQHKKKPWERFIHQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF

Kinase 89397.m00103.AA CMGC 50-332 18 2.5e-62 203.24 In-house 1-513 (513) Show / Hide
Range on Protein: 50-332
Range on HMM: 1-513/513
Sequence Identity: 18% (97 aa)

YSIGSILGSGKFSTVFKGTD----------------GKHVYAMKVYKDVRPNYIR---------------REIFMHKALR----------------KCEH
| | . .|.| ...|.|..|                .. ..|.|  | .  . .                ||| . | |.                . ..
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVQLHDVVRDPVSKST-------------TL----------LLEYHKSGN--WKN-FFPKMKISD------------IKNFM------YKLLLALD--EC
||.|.|..... |...              |          |..| |. .   ..    ...               ||.||      | .| .|.   |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSHG--IMHRDVKQQNILYNPKT-------------------GDLHLGDLGLAEVYFPY----------------------HQYEVGIGTIRFMAPEILM
|||.  |.||| | .||| |...                   | | ..| |||  | |.                      ..|   . |    |||||.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

SYRFYN---------YAIDIWSAGVILAEMIHE--------EPLFKGDYQ-----------LDILRSISRVFTASP---------------LLEFADKIG
... |.         ..||.||.| |.|||.          .|||.|.             .| |  | .|.   .                 |. ..|.
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

--------------------FEVSTNLLNA---LSSISIGQFDAILSRVRD------------------------------EYKDDDLFDLLRLMLVIDP
                     |   | ..    .  .    .  .  . ..                              .  |....|||  ||..||
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

TYRITARDALNHKFF
. |||| .||.| .|
DKRITAEQALQHPYF

Kinase 89397.m00103.AA S_TKc 50-332 25 4.3e-62 213.52 SMART 1-231 (231) Show / Hide
Range on Protein: 50-332
Range on HMM: 1-231/231
Sequence Identity: 25% (79 aa)

YSIGSILGSGKFSTVFKGTDGK--HVYAMKVYKDVRPNYIRREIFMHKALRKCEHIVQLHDVVRDPVSKSTTLLLEYHKS--GNWKNFFPK---------
| |. ..|.| |..|.|... |  ...|.|. |    . ||||| ..|   ....||.|.|| .|   ..  . .||     |. . .  |         
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

MKISDIKNFMYKLLLALDECHSHGIMHRDVKQQNILYNPKTGDLHLGDLGLAEVYFPYHQYEVGIGTIRFMAPEILMSYRFYNY-AIDIWSAGVILAEMI
.   ... .|| ...||. ||||||.|||.| .||| .     . ..| ||| ..         .||  .||||.|     |.. ..|.|| |.||.||.
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

HEEPLFKGDYQLDILRSISRVFTASPLLEFADKIGFEVSTNLLNALSSISIGQFDAILSRVRDEYKDDDLFDLLRLMLVIDPTYRITARDALN-------
  .|.|    .  ... |                                                .... |..| .|. ||. |.|| .||.       
CGYPPFP--QMQMMFKKIG-----------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

HKFF
| .|
HPWF

Kinase 89397.m00103.AA Pkinase 50-332 25 3e-56 197.97 Pfam 1-293 (293) Show / Hide
Range on Protein: 50-332
Range on HMM: 1-293/293
Sequence Identity: 25% (82 aa)

YSIGSILGSGKFSTVFKGTDGKHV--YAMKVYKDVRPNY-----IRR--EIFMHKALRKCEHIVQLHDVVRDPVSKSTTLLLEYHKSG-----NW-----
| ||...||| |..|.|... .    .|.|. | .. .       ||  || ..| | ....||.|.|...|  ...  . .||.  |      .     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

--KNFFPKMKISDIKNFMYKLLLALDECHSHGIMHRDVKQQNILYNPKTGDL----HLGDLGLAEV--YFPYHQYEVGIGTIRFMAPEILMSYRFYNYAI
  .. |  .   ..|..|| .| .|. |||.||.|||.| .|||.. ..|..    ...| |||..  | ... . .  ||...||||...... | ...
WRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DIWSAGVILAEMIHEEPLFKGD----YQLDILRSISRVFTASPLLEFADKIG----FEVSTNLLNALSSISIGQFDAILSRVRDEYKDDDLFDLLRLMLV
|.||.|.||.||.  .|.|.|.      .| .  | |.  . .  ..  ..     | ...                .  ...  . .... |... .| 
DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H------------F-HWTF-HNWSEECKDFIKWCLC

IDPTYRITARDALNHKFF
 ||. |.||...|.|..|
KDPKKRPTAEQILQHPWF

Kinase 89397.m00103.AA CAMK 55-332 17 3.9e-51 162.62 In-house 1-425 (425) Show / Hide
Range on Protein: 55-332
Range on HMM: 1-425/425
Sequence Identity: 17% (78 aa)

ILGSGKFSTVFKGTDG-K-------------HVYAMKVYK-------------------------------DVRPNYIRREIFMHKALRK------CEHI
.||.| |..|.....                . .|.|...                               ..    .|||| ..| |..       ..|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLHDVVRDPV-----------------SKSTTLLL---EYHKSGNW----------KNFF------------PKMKISDIKNFMYKLLLALDECHSHGI
..|..|  ||                   |   . .   ||   |            .  .             ... .. . ..  .. |.. ||||.|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

MHRDVKQQNILYNPKT----------------GDLHLGDLGLAEVYFP------------------------YHQYEVGIGTIRFMA-PEILMS------
.||| |  |||.. .                 ... . | |.| ...|                         . ..   ||  .|| ||.| .      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------YRFYNYAIDIWSAGVILAEMIHEEPLFKGDYQLDILRSISRVFTASPLLEFADKIGFEVSTNLLNALSSISIGQFDAILSRVRD-------EY
        . |....|.||.||||  |   .| | ||.. .|.  .                   . .|. . .  |  |..| . . . .       |.
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-D-E--W--------------IGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEW

KD-----------DDLFDLLRLMLVIDPTYRITARDALNHKFF
 |           ..  ||.| ||. ||. |.|. ..|||...
WDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 89397.m00103.AA Ciliate-E2 50-332 18 2e-45 153.89 In-house 1-365 (365) Show / Hide
Range on Protein: 50-332
Range on HMM: 1-365/365
Sequence Identity: 18% (77 aa)

YSIGSILGSGKFSTVFKG---TDGKHV----------------------YAMKVYKDVRPNYIRREIFMHKALR---------------KCEHIVQLHDV
| .  ..|.| |..|.|.    ..| .                      ||||..|    ..| .|| . . ..               .. .|......
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VRDPVSKSTTLLLEYHKSGN--------WKNFFPK------MKISDIKNFMYKLLL---------------ALDECHSHG-IMHRDVKQQNILYNPKTGD
  .   ..  | .|| . |.        .|... .      ...  ||..|...|                || ..|| . |.||| | .|||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

LHLGDLGLA-----------------EVYFPY----------------HQYEVGIGTIRFMAPEILMS--------YRFYNYAIDIWSAGVILAEMIHEE
. . |.||.                 .  |                  ...   .||  .||||||..           |.|..||||.|||| ||.  .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

PLFKGDYQLDILRSISRVFTASPLLEFADKIGFEVSTNLLNALSSISIGQFDAILSRVRD----------------------EYKDDDLF--DLLRL---
| |                                                   .    .                      ..|. ..   ||..    
PPF---------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGK

-MLVIDPTYRIT-ARDALNHKFF
 ||. ||  ||| . ..|||..|
RMLQKDPEKRITGWEQILNHPWF

Kinase 89397.m00103.AA CDC2 136-244 39 4e-34 101.87 In-house 99-212 (301) Show / Hide
Range on Protein: 136-244
Range on HMM: 99-212/301
Sequence Identity: 39% (45 aa)

KMKISDIKNFMYKLLLALDECHSHGIMHRDVKQQNILYNPKTGDLHLGDLGLA-EVYFPYHQYEVG--IGTIRFMAPEILMSYRFYNYAIDIWSAGVILA
.|  . .|..||..| ... ||...||||| | |||| . |.|.. ..| |||  . .|  .|  .  . |    |||||.  ..|. ..|.|| | |.|
HMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILID-KKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFA

EM---IHEEPLFKGD
||   .. .||| ||
EMFMDVTKKPLFHGD

Kinase 89397.m00103.AA Ciliate-E2-Unclassified 50-332 18 8.7e-32 107.55 In-house 1-352 (352) Show / Hide
Range on Protein: 50-332
Range on HMM: 1-352/352
Sequence Identity: 18% (70 aa)

YSIGSILGSGKFSTVFKGTDGKHVYA-----MKVYKDVRPNYIRR---------EIFMHK-------------ALR--KCEHIVQLHDVVRDPVSKSTTL
| |. ..|.| |..|.|  . |. ..     ||.....  ..|..         |.. .|              |.  ....|| .... .|   .   .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQD--KQNIYI

LLEYHKSGNWKNFFPKMKI--------------------SDIK-----NFMYKLLLALDECHSHG-IMHRDVKQQNILYNPKTG--DLHLGDLGLA----
 .|| . |. ...  |.|                       .|     .... .|..|. .|. . | ||| | .|||.. . .   . . |.|..    
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

-----EVYF--------PYHQYEVGIGTIRFM----APEILMSYRFYN---YAIDIWSAGVILAEMIHEEPLFKGDYQLD----------------ILRS
     . ..        ... .   .||...|    |||.|..   ..   |..|||| |||| ||.  .. |..  . .                ... 
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

I-SRVFTASPLLE--FADKIGFEVSTNLLNALSSISIGQFDAILSRVRDEYKDDDLFDLLRLMLVIDPTYRITARDALNHKFF
|  . .  ..  .  . ... .|.   .                             |||. ||. .| .|||. ..||| .|
IKQKNIQFPKFPWQQIPKHWSPEAKDFIN----------------------------DLLQKMLKKNPNKRITFEQILNHPWF

Kinase 89397.m00103.AA CDK5 50-253 36 1.3e-30 93.55 In-house 1-212 (287) Show / Hide
Range on Protein: 50-253
Range on HMM: 1-212/287
Sequence Identity: 36% (79 aa)

YSIGSILGSGKFSTVFKGT--DGKHVYAMK-VYKDVR----PNYIRREIFMHKALRKCEHIVQLHDVVRDPVSKSTTLLLEYHKSGNWK---NFFPKMKI
|.    .| | . ||.|.   . . ..|.| |  |      |    ||| . | | | . || ||||.     |  ||  |.      |   ..  .|  
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKEL-KHKNIVRLHDVIH--SEKKLTLVFEFCDQDLKKYMDSCNGEMDM

SDIKNFMYKLLLALDECHSHGIMHRDVKQQNILYNPKTGDLHLGDLGLAEVY-FPYHQYEVGIGTIRFMAPEILMSYRFYNYAIDIWSAGVILAEMI-HE
  || ||| ||  |  ||.| ..||| | || | | | | | |.| |||  .  |   |   . |  . .| .||  . |.  ||.||.| |.|||.   
HIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLIN-KNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAG

EPLFKGDYQLDILRSI
 ||| |  . | |  |
RPLFPGNDVEDQLKRI

Kinase 89397.m00103.AA CAMKL 50-231 27 9.1e-27 82.33 In-house 1-226 (297) Show / Hide
Range on Protein: 50-231
Range on HMM: 1-226/297
Sequence Identity: 27% (63 aa)

YSIGSILGSGKFSTVFKGTDG---KHVYAMKVYKDVRPNY------------------IRREIFMHKALR--KCEHIVQLHDVVRDPVS----KSTTLLL
| ||  || | |..|  .|.    .. .|.|...  . .                   |||||  .| |.  | ..|..|..|. .|      |   | .
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYHKSGN-------WKNFFPK--MKISDIKNFMYKLLLALDECHSHGIMHRDVKQQNILYNPKTG-DLHLGDLGLAEVYFP-----YHQYEVGIGTIRFM
||. .|.        |.  ..  |. .. . .   .. |.. |||||| ||| |  |||   .    . . | |..  | |      .  .   |.  .|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEILMS-YRFYN-YAIDIWSAGVIL
||||. .  . |. ...||||.||||
APEIFQGNNKPYDGPKVDIWSCGVIL

Kinase 89397.m00103.AA CDK 50-188 27 1.8e-24 75.07 In-house 1-160 (284) Show / Hide
Range on Protein: 50-188
Range on HMM: 1-160/284
Sequence Identity: 27% (48 aa)

YSIGSILGSGKFSTVFKGTDGK-------HVYAMKVYK----------DVRPNYIRREIFMHKALRKCEHIVQLHDVVRDP-VS--------KSTTLLLE
| .   .| | . .|.|. | .       ...|.|  .          .  |    ||| . | |  ...||.||||. .   .        .. ..  |
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

Y--------HKSGNWKNFFPKMKISDIKNFMYKLLLALDECHSHGIMHRDVKQQNILYNPKT----GDLHLGDLGLA
|         .               ||..|. || .|. |||..||||| | ||||.| .     |.| ..| |||
YMDHDLKKYMD---------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLA

Kinase 89397.m00103.AA CDC7 100-190 31 2.8e-18 49.86 In-house 68-158 (522) Show / Hide
Range on Protein: 100-190
Range on HMM: 68-158/522
Sequence Identity: 31% (29 aa)

CEHIVQLHDVVRDPVSKSTTLLLEYHKSGNWKNFFPKMK--ISDIKNFMYKLLLALDECHSHGIMHRDVKQQNILYNPKTGDLHLGDLGLAEV
.. ...... .|  .  .... ..| .    . |.  |.  .. ||  || |..||   |. || |||||  |.|||..|.   | | |||..
HHNVMGMCCCFR--YNDHVHIVMPYFPHCSFQDFYFHMNRDMEEIKHYMYNLFYALRHVHQFGIIHRDVKPSNFLYNRRTKKFLLVDFGLAQH

Kinase 89397.m00103.AA CDK 208-257 41 4.7e-14 41.2 In-house 187-241 (284) Show / Hide
Range on Protein: 208-257
Range on HMM: 187-241/284
Sequence Identity: 41% (23 aa)

APEILMSYRFYN--YAIDIWSAGVILAEMIH---EEPLFKGDYQLDILRSISRVF
|||.|.  . |.   .||.||.| |.|||.     .||| ||  .| |  |.|..
APELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRIC

Kinase 89397.m00103.AA CDC2 306-332 51 1.7e-12 34.17 In-house 275-301 (301) Show / Hide
Range on Protein: 306-332
Range on HMM: 275-301/301
Sequence Identity: 51% (14 aa)

FDLLRLMLVIDPTYRITARDALNHKFF
.|||. ||..||  ||.|..||.|..|
IDLLMQMLQYDPQKRISAKEALQHPYF

Kinase 89397.m00103.AA CDC7 302-332 48 9.5e-11 26.84 In-house 492-522 (522) Show / Hide
Range on Protein: 302-332
Range on HMM: 492-522/522
Sequence Identity: 48% (15 aa)

DDDLFDLLRLMLVIDPTYRITARDALNHKFF
.| ..||| . | ..|  |||| .||.| ||
PDEAYDLLDRCLEMNPHKRITAEEALKHPFF

Kinase 89397.m00103.AA CDC7 201-231 51 1.2e-10 26.52 In-house 329-359 (522) Show / Hide
Range on Protein: 201-231
Range on HMM: 329-359/522
Sequence Identity: 51% (16 aa)

IGTIRFMAPEILMSYRFYNYAIDIWSAGVIL
.||  |.||| |. ..   .||||||.|||.
AGTPGFRAPEVLLKCPDQTTAIDIWSCGVIF

Kinase 89397.m00103.AA CDK 307-332 53 3.3e-10 28.67 In-house 259-284 (284) Show / Hide
Range on Protein: 307-332
Range on HMM: 259-284/284
Sequence Identity: 53% (14 aa)

DLLRLMLVIDPTYRITARDALNHKFF
|||  ||. ||. ||.| .||.|..|
DLLNKMLCYDPKKRISAEQALQHPYF

Kinase 89397.m00103.AA CDK5 302-332 45 5.9e-10 27.15 In-house 257-287 (287) Show / Hide
Range on Protein: 302-332
Range on HMM: 257-287/287
Sequence Identity: 45% (14 aa)

DDDLFDLLRLMLVIDPTYRITARDALNHKFF
|  . |||  ||...|  ||.| .||.| .|
DEKGMDLLQKMLQCNPNQRISAKAALHHPYF

Kinase 89397.m00103.AA TyrKc 50-332 18 2.7e-09 -72.31 SMART 1-280 (280) Show / Hide
Range on Protein: 50-332
Range on HMM: 1-280/280
Sequence Identity: 18% (59 aa)

YSIGSILGSGKFSTVFKGTDGKHVYAMKVYKDVRPNYIRREIFMHKAL-RKCEHIVQLHDVVRDP-----VSKSTTLLLEYHKSGNWKNFFPKMK----I
 . | .||.| | .|.|||      | |. |.     ..||. . . |  . ..||.|. |....      ..   ...|| . |. |..  | .     
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCM

SDIKNFMYKLLLALDECHSHGIMHRDVKQQNILYNPKTGDLHLGDLGLAEVYFPY-------HQYEV-----GI--GTIRFMAPEILMSYRFYNYAIDIW
.|  .|..      .  ||... |||    |.|.. .      .| ||.     .         | .     |     || |||| .  |. .. . |.|
KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSDVW

SAGVILAEMI-HEEPLFKG-----DYQLDILRSISRVFTASPLLE----FADKIGFEVSTNLLNALSSISIGQFDAILSRVRDEYKDDDLFDLLRLMLVI
| || . |.    ..   |         .... . . .   .  .                                 .        |..... .     
SFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------------F----VCCPDEMYQIMKQCWHE

DPTYRITARDALNHKFF
||  | | ..   |..|
DPEDRPTFSEI--HECF

Kinase 89397.m00103.AA CAMKL 307-332 38 4.8e-09 24.84 In-house 272-297 (297) Show / Hide
Range on Protein: 307-332
Range on HMM: 272-297/297
Sequence Identity: 38% (10 aa)

DLLRLMLVIDPTYRITARDALNHKFF
||.| ||. .|..|.|. . .||...
DLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase 89397.m00103.AA CDC7 50-69 40 0.002145 4.36 In-house 1-20 (522) Show / Hide
Range on Protein: 50-69
Range on HMM: 1-20/522
Sequence Identity: 40% (8 aa)

YSIGSILGSGKFSTVFKGTD
| . . .|.| ||.|.|.|.
YKVHDKIGEGTFSSVYKATC