Gene 81812.m00091 (T.vaginalis)

81812.m00091

Species: T.vaginalis
Alias: 81812.m00091, TvagK0150
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
81812.m00091.AA Protein None 333 None Fasta, JSON
81812.m00091.kin_dom Protein Kinase Domain None 244 None Fasta, JSON

Protein domain

Protein domains of 81812.m00091.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 81812.m00091.AA S_TKc 24-267 27 1.6e-73 251.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 24-267
Range on HMM: 1-231/231
Sequence Identity: 27% (72 aa)

YSFVRTIAQGGYGIVFEMHSNKYNIDYAVKRIPKCFLSNSELDCLMQIDDPYIVRLYQVFYLGDFIYMVMELCQN---DLFNIFTSSQQ------LSDEQ
| ..|.| .|..| |.  . .| .  .|.|.|.      .|...|.. . |.||.|| ||.  |..|||||.| .   ||| .  . .       ..  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

MKKYALEMVLAIKSIHDRNIAHCDIKPANFFIDNYGRVKIGDFGLSSINGTATTCKIQKGTRLYMAPEMYVLKEYNAMKSDIWSLGVSLYYMATKQYPFN
 ..|. ....|.. .|...| |.|.||.| ..|.  ..||.||||. .       . . ||. |||||.     |.  |.|.||.|. || |.. . || 
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP

APDQSKLEQVVNIGLFPKEQVRDKQLLGLICRCLEKNPCRRPSINDLLR-------IPYL
      .... .. .       ..... .|..||.|.| .||.. ..|.        |..
-----QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 81812.m00091.AA Pkinase 24-267 27 3.5e-63 221.01 Pfam 1-293 (293) Show / Hide 
Range on Protein: 24-267
Range on HMM: 1-293/293
Sequence Identity: 27% (81 aa)

YSFVRTIAQGGYGIVFEMHSNKYNIDYAVKRIPKCFLSN---------SELDCLMQIDDPYIVRLYQVFYLGDFIYMVMELCQN-----DLFNIFT--SS
| ..|.| .|..| |.. |  .... .|||.|.|.  .          ||.  .  .. |.||||| .|. .| ||||||.|..     ||| . .  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

QQL--SDEQMKKYALEMVLAIKSIHDRNIAHCDIKPANFFIDNYGRV----KIGDFGLSSI--NGTATTCKIQKGTRLYMAPEMYVL-KEYNAMKSDIWS
  .  |... |.|..... ... .|...| |.|.||.|..||| | .    ||.||||.    .   . ..   ||. |||||  ..  .|   |.|.||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV-IRGGQYYGPKVDMWS

LGVSLYYMATKQYPFNAP----DQSKLEQVVNIGL----FPKEQVRD-------------------KQLLGLICRCLEKNPCRRPSINDLLRIPYL
.|. ||.|.... ||       . .... ...|.     |. .. ..                   . .. .|..||.|.| .||.. ..|  |..
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81812.m00091.AA CAMKL 24-267 24 5.7e-59 186.76 In-house 1-297 (297) Show / Hide 
Range on Protein: 24-267
Range on HMM: 1-297/297
Sequence Identity: 24% (73 aa)

YSFVRTIAQGGYGIVFEMHSNKY-NIDYAVKRIP------KCFLSNS--------------ELDCLMQID---DPYIVRLYQVFYLGDF------IYMVM
| ...|. .|..| |   .  .. .. .|.| |       ... ..               |  ......    | |..||.|..  ..      ||.||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCQND---LFNIFTSS----QQLSDEQMKKYALEMVLAIKSIHDRNIAHCDIKPANFFIDNYG--RVKIGDFGLSSI-----NGTATTCKIQKGTRLYM
|.|..    ||.   .     . .. .. ..|   .| |.. .|...|.| |||| |  .|. |   .|| |||.| .     .|.  ..|.. |.  ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEMYVL--KEYNAMKSDIWSLGVSLYYMATKQYPFNAPD---------QSKLEQVVNIGLFPKEQVRDKQLLGLICRCLEKNPCRRPSINDLLRIPYL
|||..    |.|.. | ||||.|| || | . ..||....           .... .  . .|.    . ..  || . |..|| .||.| .... | .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 81812.m00091.AA CAMK 29-267 17 2.3e-56 179.78 In-house 1-425 (425) Show / Hide 
Range on Protein: 29-267
Range on HMM: 1-425/425
Sequence Identity: 17% (73 aa)

TIAQGGYGIVFEMHSNKYN------------IDYAVKRIPKCFLSN---------------------------------SELDCLMQ-------IDDPYI
|. .|..|.|..    . .              .|.| |.|  |..                                 .|......       .| | |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLYQVFYLGDF-------------------IYMVM---ELCQN-----DLFNIFTSSQQ---------------LSDEQMKKYALEMVLAIKSIHDRNI
..||.|.  ...                   .||||   |.|..     |||.  ..  .               .. .. ..|   .. |.. .|..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHCDIKPANFFIDNY-----------------GRVKIGDFGLSSINGT------------------------ATTCKIQKGTRLYMA-PEMYVL------
.|.|.|| |  .|.                  . .|| |||.. .                              .| . ||  ||| ||.         
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------KEYNAMKSDIWSLGVSLYYMATKQYPFNAP-------------DQSKLEQVVNIGLF--PKEQVRD----------------------KQLLG
       |.|   |.|.||.|| || | .  .||...             ....| . .  | .  | ... .                      ..   
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LICRCLEKNPCRRPSINDLLRIPYL
||...|...| .|..| . |. | .
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 81812.m00091.AA AGC 24-267 18 2.8e-51 129.73 In-house 1-395 (395) Show / Hide 
Range on Protein: 24-267
Range on HMM: 1-395/395
Sequence Identity: 18% (75 aa)

YSFVRTIAQGGYGIVFEMHSN------KYNIDYAVKRIPKCF-----------LSNSE------------LDCLMQID----------DPYIVR-LYQVF
. |...| .|..| |.    .        .  ||.| . |               ..|             . |....           |.||. |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

YLGDF--IYMVMELCQ----------N-DLFNIFT---SSQQLSDEQMKKYALE-------MVLAIKSIHD-RNIAHCD-IKPANFFIDNYGRVKIGDFG
   |   .|.|||...            .|| .      .. .. |. . || |       .|||. ..|. ..| | | .|| |  .|. | .|. |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSSING-------------------------------------------------------TATTCKIQKG--TRLYMAPEMYVLKEYNAMKSDIWS--L
|. ..                                                        | | |    |  |  |||||.           |.||  |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFC----GPCTPEYMAPEIL-----YGKACDWWSFGL

GVSLYYMATKQYPFNAP----------DQSKLEQVVNIG----------------LFPKEQVRDKQLLGLICRCLEKNPCRRPS----------INDLLR
|. .| | | . ||..           .. .. | . .|                 ||...  ....  || ..|.|.| .|.           .... .
GCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKN

IPYL
 |. 
HPWF
Kinase 81812.m00091.AA Ciliate-E2-Unclassified 24-267 22 3.6e-51 175.72 In-house 1-352 (352) Show / Hide 
Range on Protein: 24-267
Range on HMM: 1-352/352
Sequence Identity: 22% (81 aa)

YSFVRTIAQGGYGIVFEM-HSNKYNIDYAVKRIPKCFLSN--------------SELDCLM----------------QIDDPYIVRLYQVFYLGDFIYMV
| ....| |||.|.|... |....   || | . |    .               |. ...                ....|.||... .|   . ||.|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MELC------------------QNDLFNIFTSSQQLSDEQMK-----KYALEMVLAIKSIHDRN-IAHCDIKPANFFIDNYG---RVKIGDFGLSSINGT
||.|                  .||||.   ........|.|     .|. . .......|  | | | |||| | ..|| |   ..|| |||.|. ...
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

ATTCKIQK-----------------GTRLYM----APEMYVLKEYNAM---KSDIWSLGVSLYYMATKQYPFNAPDQSK----------------LEQVV
   |.  .                 ||  ||    |||..  ..|. .   |.||||||| ||.| . .|||..... .                |.|  
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

NIG---LFPKEQ-----VRDKQLL----GLICRCLEKNPCRRPSINDLLRIPYL
. .    .. ..       ...       |....|.|||  |......|  |..
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 81812.m00091.AA Ciliate-E2 24-267 20 2.3e-48 164.13 In-house 1-365 (365) Show / Hide 
Range on Protein: 24-267
Range on HMM: 1-365/365
Sequence Identity: 20% (78 aa)

YSFVRTIAQGGYGIVFEM----HSNKYNID-------------------YAVKRIPKC--FLSNSELDCLM----------------QIDDPYIVRLYQV
| |.. | ||..|.|...      ....|                    ||.|.. |   .  ..|.. ..                |.. |.|...| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FY--LGDFIYMVMELCQN-DLFN------IFTSSQ-----QLSDEQMKKYALEMVL---------------AIKSIHDRN-IAHCDIKPANFFIDNYGRV
|.    . ||.|||.||  |||       ..  ..     .......|..  . .                |....| .| | | |||| | ..     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIGDFGLSSINGT----------ATTCKIQK-----------------------GTRLYMAPEMYVLKEYNA--------MKSDIWSLGVSLYYMATKQY
|| ||||| .. .          .  ..  |                       ||  |||||..  |.|.          |.||||||| ||.| ....
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFNAPDQSKLEQVVNIGLFP-------------KEQVRDKQLLGLICR----CLEKNPCRRPS-INDLLRIPYL
||    | .... ...  .              . .  ...   || .    .|.|.|  |.. ....|  |..
PF---QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 81812.m00091.AA ULK 24-267 23 4.7e-48 165.95 In-house 1-324 (324) Show / Hide 
Range on Protein: 24-267
Range on HMM: 1-324/324
Sequence Identity: 23% (76 aa)

YSFVRTIAQGGYG-IVFEMHSNKY---NIDYAVKRIPKCFLSNSELD--------CLM-------QID---DPY--IVRLYQVFYLGDF--IYMVMELCQ
|.  . . .| .|  |..   .|    | ..|.| |.|. .......         |.       ...    |.  ||.|| .|.  ..  ||..||.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

N-DLFNIFTSSQQ---------LSDEQMKKYALEMVLAIKSIHDRNIAHCDIKPANFFIDNY------------GRVKIGDFGLSSINGT----ATTCKI
  ||...    .          || .. ...    . . | .|..|| |.||||.|  | |             |..||.|||.. .       .. |. 
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

QK------GTRLYMAPEMYVLK----EYNAMKSDIWSLGVSLYYMATKQYPFNAPDQSKLEQVVNIGL-----------------FP---KEQVRDKQLL
..      || |||||.    .    .|.  |.||||||. .|.| . .|||...  .....  .. |                 ||   |.... ... 
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

GLICRCLEKNPCRRPSINDLLRIPYL
 || |.|....  | |. ... .| .
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 81812.m00091.AA ULK 24-267 22 2.5e-47 163.3 In-house 1-329 (329) Show / Hide 
Range on Protein: 24-267
Range on HMM: 1-329/329
Sequence Identity: 22% (75 aa)

YSFVRTIAQGGYGIVFEMHSNKY----NIDYAVKRIP---KCFLS------------NSELDCLMQID----DPY----IVRLYQVFYLGDF--IYMVME
|.  . . .| .| |..   .|     |...|.| |.   .   .            ..| . . ...     ..    ||.|| .|.  ..  ||..||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCQN-DLFNIFTSSQQ----------LSDEQMKKYALEMVLAIKSIHDRNIAHCDIKPANFFIDNY------------GRVKIGDFGLSSI-NGT-----
.|.  ||...    .           || .. ...    . . | .|..|| |.||||.|  |.|             |..||.|||..   .       
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-ATTCK----IQKGTRLYMAPEMYVLK----EYNAMKSDIWSLGVSLYYMATKQYPFNAPDQSKLE-----QVVNIGL------------FP---KEQVR
 ..||.    . .|| |||||.    .    .|.  |.||||||. .|.| . ..||.|.  ...      . .|...            ||   .....
MMMTCVNEKRL-CGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

DKQLLGLICRCLEKNPCRRPSINDLLRIPYL
 ...  || |.|....  | |. .|. .| .
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 81812.m00091.AA MARK 24-267 29 1.7e-42 136.81 In-house 1-262 (262) Show / Hide 
Range on Protein: 24-267
Range on HMM: 1-262/262
Sequence Identity: 29% (78 aa)

YSFVRTIAQGGYGIVFEMHSNKYNIDYAVKRIPKCFLSN--------SELDCLMQIDDPYIVRLYQVFY--LGDF-IYMVMELCQN-DLFNIFTSS--QQ
| ...|| .|.|. |   .. .... .|.| ..|  |.         .|.. ....| |.|..|..|.        ||..||.. . .|..   .     
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSDEQMKKYALEMVLAIKSIHDRNIAHCDIKPANFFIDNYG--RVKIGDFGLSSINGTATTCKIQKGTRLYMAPEMYVLKEYNAMKSDIWSLGVSLYYMA
|. |  ...   .| |..  |..||.|.|||| |  ||  |   .|| |||.| .  . .  ..  ||  |||||.   |.|.. | ||||||| ||.| 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TKQYPFNAPD--QSKLEQVVNIGLFP-----KEQVRDKQLLGLICRCLEKNPCRRPSINDLLRIPYL
. ..|| . .  . .|.. .. | ..       . |.     ||.| |  || .||.| .... | .
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRN-----LIQRLLTVNPEERPTIEEIMKHPWM
Kinase 81812.m00091.AA STE 24-267 17 4.6e-40 139.18 In-house 1-359 (359) Show / Hide 
Range on Protein: 24-267
Range on HMM: 1-359/359
Sequence Identity: 17% (66 aa)

YSFVRTIAQGGYGIVFEM---------HSNKY------NIDYAVKRIPKCFLSN----------------------SELDCLMQID--DPYIVRLYQVFY
. ... | .|..| |.           ....       .  .|.|.....  .|                       |.. ... .   |.||. |  ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

LG-------DFIYMVMELCQN----DLFN-IFTSSQQLS----------DEQMKKYALEMVLA-IKSIHDRNIAHCDIKPANFFIDNYGRVKIGDFGLSS
 .       | ....||.. .    |. .  .   ..|.           .| .... . . .  . .|. .| | |||||| ..     ||. |||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

INGT-----------------ATTCKIQKGTRLYMAPEMYVL------KEYNAMKSDIWSLGVSLYYMATKQYPF---NAP-----DQSK------LEQV
.                    .  ..   ||  .||||.         |.|.. |.||||||  .  ||| ..|.   . .      . .      .||.
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDT-KCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

VNIGLFPKEQVRD----------------------KQLLGLICRCLEKNPCRRPSINDLLR--IPYL
 .|  .|  .  |                      . .   | .||.|.|  ||. ..||.   | .
-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 81812.m00091.AA CMGC 24-200 18 1.1e-31 100.65 In-house 1-322 (513) Show / Hide 
Range on Protein: 24-200
Range on HMM: 1-322/513
Sequence Identity: 18% (59 aa)

YSFVRTIAQGGYGIVFE--------------MHSNKYNIDYAVKRIPKCFLSN-----------------SELDCLMQI-----------------DDPY
|  .. | .| ||.|..               | ...|  .|.|.| . |                     |. .|...                 ....
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVRLYQVFYLGD-----------------FIYMVMELCQNDLFNIFTSSQ---------QLSDEQ------------MKKYA------LEMVLAIK--SI
||.|| .||  .                  .|.|.|....||...  . |          ||. .             |..         .  ..|   .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HDRN--IAHCDIKPANFFIDN--------------------YGRVKIGDFGLSSINGTA------------------------TTCKIQKGTRLYMAPEM
| ..  | |.|.||.|  |..                     ||.||.||||. . ..                          |  ..  || | ||| 
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVV--TRWYRAPEI

YV-LKEYN--------AMKSDIWSLG
 .  |.|.          . |.||.|
LLGWKHYTNHNYSMHYTTPIDMWSVG
Kinase 81812.m00091.AA TyrKc 24-271 19 3.3e-12 -25.36 SMART 1-280 (280) Show / Hide 
Range on Protein: 24-271
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

YSFVRTIAQGGYGIVFEMHSNKYNIDYAVKRIP----KCFLSNSELDCLMQI--DDPYIVRLYQVFYLG-------DFIYMVMELCQN---DLFNIFTSS
 .. ...  | .|.|.. . .   |. ||| .     . |.  .|.  ....  . | ||||| |   .       . ...|||.. .   . .   .  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFM--REARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

QQLSDEQMKKYALEMVLAIKSIHDRNIAHCDIKPANFFIDNYGRVKIGDFGLSSINGTA-------TTCKIQK--GTR--L---YMAPEMYVLKEYNAMK
. |. ... ....        .|..|. | |.   |  ... ..|||.|||||   .          . . ..  |..  |    ||||    ....  |
K-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TK

SDIWSLGVSLYYMAT--KQYPFN-----APDQSKLEQVVNIGLFPKEQV--------RDKQLLGLICRCLEKNPCRRPSINDLLRIPYLKEQL
||.|| || .. . |  .| . .      ..|  .|.| . .  |. .           . .  .. .| . .|  ||. ...      .|..
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------HECF
Kinase 81812.m00091.AA CMGC 237-267 29 1.2e-05 13.47 In-house 483-513 (513) Show / Hide 
Range on Protein: 237-267
Range on HMM: 483-513/513
Sequence Identity: 29% (9 aa)

DKQLLGLICRCLEKNPCRRPSINDLLRIPYL
|.|.. |....|. .| .|... . |. ||.
DPQAIDLLKKMLQYDPDKRITAEQALQHPYF