95537.m00095

Species: T.vaginalis
Alias: 95537.m00095, TvagK0571
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
95537.m00095.AA Protein None 334 None Fasta, JSON
95537.m00095.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of 95537.m00095.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Pkinase 95537.m00095.AA Pkinase 22-270 28 3.4e-81 280.87 Pfam 1-293 (293) Show / Hide
Range on Protein: 22-270
Range on HMM: 1-293/293
Sequence Identity: 28% (84 aa)

YRVVRTIGKGGFAVVVLGVNPKTQKQVAIKIISREEVTKRNLMQYLE-NELRLSTRFDHPNVCKVLDVIYEEDIIMVVMEYFKNG----DLQSMLS--NG
|...|.||.|.|..| .... .|.|.||.|||....  .  ... .  .|...  |..|||... .|. ...| | .||||  .|    || ...|  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

VNF--TYEQKCKISFDILQGINYLHKRDISHRDIKPENVLLDDDFTP----KLIDFGLA----KENGTSLHTYCGTPFYMAPEVIISDTYDGIKADIWAF
 .|  .... ...   ||.|..|.|.. | |||.||||.|.|.. ..    |..|||||      |.. ..|.||||.||||||| ...|.| |.|.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVTVHVLSTGKFPWYVK------NDVQLIRELQANKLELIIEPT---------------------GVLGTLISKCLVFDSKKRSSSSDLLTL--L
|.... . .|..|.. .      .. |.|..    .|.  .. .                       .  .|..|| .| ||| .  ..|    .
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

S_TKc 95537.m00095.AA S_TKc 22-270 29 1.7e-76 261.4 SMART 1-231 (231) Show / Hide
Range on Protein: 22-270
Range on HMM: 1-231/231
Sequence Identity: 29% (78 aa)

YRVVRTIGKGGFAVVVLGVNPKTQKQVAIKIISREEVTKRNLMQYLENELRLSTRFDHPNVCKVLDVIYEEDIIMVVMEYFKN--GDLQSMLSNGVN---
|...|.||||.|..| .... ||...||||||.          . ...|...  . .|||..| .||... | . .||||  .  ||| ... .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FTYEQKCKISFDILQGINYLHKRDISHRDIKPENVLLDDDFTPKLIDFGLAKENGTSLHTYCGTPFYMAPEVIISDTYDGIKADIWAFGVTVHVLST
   |.  . ...   |.....|.|.. | |||.||||.|||.  . |..|||||..     .|.||||.||||||.    |.. |.|.|..|...  . .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GKFPWYVKNDVQLIRELQANKLELIIEPTGVLGTLISKCLVFDSKKRSSSSDLLT---------LL
|. |..  .. .... .          .  ..  .|.|||..| .|| .  ..|.          .
GYPPFP--QMQMMFKKIG---------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 95537.m00095.AA CAMK 27-267 20 1.9e-72 232.58 In-house 1-420 (425) Show / Hide
Range on Protein: 27-267
Range on HMM: 1-420/425
Sequence Identity: 20% (85 aa)

TIGKGGFAVVVLGVNPKTQ------------KQVAIKIISREEVTK-------------------------RNLMQYLENELRLSTR-------FDHPNV
|.|.|.|..| |... .|.            ..||||||... ...                          . .. ...|...  .        ||||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

CKVLDVIY--------------------EEDIIMVV--MEYFKNG----DLQSMLSNGVN---------------FTYEQKCKISFDILQGINYLHKRDI
.| ..|.                     .....||   |||  .|    || ...    .               || .. ...   |.....|.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

SHRDIKPENVLLDDD-----------------FTPKLIDFGLA--KEN------------------------GTSLHTYCGTPFYMA-PEVIIS------
 |||.||||.||||.                 .. |.||||.|  ..                         |  ..|.|||| ||| |||. .      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------DTYDGIKADIWAFGVTVHVLSTGKFPWYVK-------------NDVQLIRELQANKLELIIEPTGV------------------------LGT
        .|.| |.|.|. ||   .. .|..|.| .             || .| .  .. | . . ..                              
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LISKCLVFDSKKRSSSSDLL
||.|.|. | .|| . .. |
LIRKMLQVDPEKRMTIEQCL

Kinase 95537.m00095.AA CAMKL 22-260 28 8.4e-71 225.14 In-house 1-285 (297) Show / Hide
Range on Protein: 22-260
Range on HMM: 1-285/297
Sequence Identity: 28% (81 aa)

YRVVRTIGKGGFAVVVLGVN-PKTQKQVAIKIISREEVT-KRNLMQY-----------LENELRLSTRFD---HPNVCKVLDVIYEEDI------IMVVM
||...|.|||.|..| |...   |...|||||| ..  . . . ..            .. | ..  ...   |||..| ..||. ..       |  ||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYFKNGD--LQSML--SNGVN--FTYEQKCKISFDILQGINYLHKRDISHRDIKPENVLLDDDF--TPKLIDFGLAKE---N----GTSLHTYCGTPFYM
||  .|.  |. ..    ...  .. .. ...   |. ..||.|...| ||||||||.|||..   . |.||||.. .   .    |  |.| ||.| ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVIIS--DTYDGIKADIWAFGVTVHVLSTGKFPWY-------VKNDVQLIRELQANKLELI-IE--PTGVLGTLISKCLVFDSKKR
|||.. .  . ||| |.|||. ||.  .. .|..|.         |... . .. .    . . |   .   .  ||.| |. . .||
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKR

Kinase 95537.m00095.AA ULK 22-260 24 1.9e-61 210.46 In-house 1-312 (324) Show / Hide
Range on Protein: 22-260
Range on HMM: 1-312/324
Sequence Identity: 24% (77 aa)

YRVVRTIGKGGFA-VVVLGVNPKT---QKQVAIKIISREEVTKRNLM-------QYLENELRLSTRFD---HPN--VCKVLDVIYEEDI--IMVVMEYFK
| . . .||| |. .|  | | ||   ...||.|.|.. .  | ...       | |.|| ..   ..   |||  ..| .|. .. .   |  .|||  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGDLQSMLS---------NGVNFTYEQKCKISFDILQGINYLHKRDISHRDIKPENVLLDDDF------------TPKLIDFGLAKENG------TSLHT
 |||.. .          .. ... ..  ..  .|..|  .|||. | ||||||.| |. ...            . |. |||.||         . ..|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

YC------GTPFYMAPEVIISD----TYDGIKADIWAFGVTVHVLSTGKFP---WYVKNDV----QLIRE-------LQANKLELI-----IEPTGVLGT
..      ||| ||||... .      |. .|.||| .|.  . . .|| |   |   ...    .||.         . ....       .     .  
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LISKCLVFDSKKR
||...|..| |.|
LIRRMLQYDEKDR

Kinase 95537.m00095.AA Ciliate-E2 22-267 22 4.7e-60 204.82 In-house 1-360 (365) Show / Hide
Range on Protein: 22-267
Range on HMM: 1-360/365
Sequence Identity: 22% (85 aa)

YRVVRTIGKGGFAVVVLGVNPKTQKQ-----------------------VAIKIISREEVTKRNLMQYLE----------NELRLSTRFDHPNVCKVLDV
| ... ||.|.|..| .. . |.|||                       .|.||..  ..   . ....           ||...  . .|||..|  ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IY--EEDIIMVVMEYFKNGDLQSMLSNG-----------VNFTYEQKCKISFDILQ---------------GINYLHKRD-ISHRDIKPENVLLDDDFTP
 .   .. |  ||||.. |||.. . |             .|| .. ..|.  |||               ...|||..  | ||||||||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLIDFGLAKENGTS----------------------------------LHTYCGTPFYMAPEVIISDTYDG--------IKADIWAFGVTVHVLSTGKFP
|.|||||.|.. ..                                   .|.|||| |||||.. .  ||.         |.|||..||. . . .||.|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WYVKNDVQLIRELQANKLELIIEPTGVLG---------------TLISK----CLVFDSKKRSS-SSDLL
.    . ..  ... .. | . . |  .                 ||.|    .|. | .|| .  ...|
F---QQQIKQCKIDFPCPEWQKD-TQ-CIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQIL

Kinase 95537.m00095.AA ULK 22-260 25 1.7e-59 203.94 In-house 1-317 (329) Show / Hide
Range on Protein: 22-260
Range on HMM: 1-317/329
Sequence Identity: 25% (82 aa)

YRVVRTIGKGGFAVVVLGVNPKT----QKQVAIKIISREEVTKRNLMQY-------LENELRLSTRFD--------HPNVCKVLDVIYEEDI--IMVVME
| . . .||| |..|  | | ||    ...||.|.|....  . | .|.       |.|| ..  . .        |||..| .|. .. .   |  .||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YFKNGDLQSMLS----------NGVNFTYEQKCKISFDILQGINYLHKRDISHRDIKPENVLLDDDF------------TPKLIDFGLAKENGTS-----
|   |||.. ..          .. ... ..  ..  .||.|  .|||. | ||||||.|.|.....            . |. |||.||    .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-LHTYC------GTPFYMAPEVIISD----TYDGIKADIWAFGVTVHVLSTGKFP---WYVKNDV-QLIRELQAN---------KLELIIE-------PT
 ..|.       ||| ||||... .      |.  |.||| .|.  . . .|| |   |    .. | |..|  |         |  | ..         
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

GVLGTLISKCLVFDSKKR
  .  ||...|..| |.|
PECKDLIRRMLQYDEKDR

Kinase 95537.m00095.AA Ciliate-E2-Unclassified 22-267 23 2.4e-56 193.53 In-house 1-347 (352) Show / Hide
Range on Protein: 22-267
Range on HMM: 1-347/352
Sequence Identity: 23% (82 aa)

YRVVRTIGKGGFAVVVLGVNPKTQKQV-----AIKIISRE-EVTKRNLMQYLENELRLSTRF----------------DHPNVCKVLDVIYEEDI--IMV
|.....||.|||..| . .. |.. |.     ..||...     ...  ... .....  .                 .||. ..| .. ...|   |  
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEYFKNGDLQSMLSN-----------------GVNFTYEQKC-----KISFDILQGINYLHKRD-ISHRDIKPENVLLDDD---FTPKLIDFGLAKENG
||||...|||. ....                 .  || .| .     ..   ||||..|||.   | ||||||||.|.|..   . .|.||||..|...
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

TS------------------LHTYCGTPFYM----APEVIISDTYDG---IKADIWAFGVTVHVLSTGKFPWYVKNDVQ----------------LIREL
..                  ..| |||| ||    ||||. .  ||.   .|.|||..||  . . .|..| | .|. |                |... 
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

QANKLE----------LIIEPTG--VLGTLISKCLVFDSKKRSSSSDLL
......           .. |..   .  |..|.|. . .|| . ...|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQIL

Kinase 95537.m00095.AA TKL 28-270 20 4.1e-54 186.11 In-house 1-364 (364) Show / Hide
Range on Protein: 28-270
Range on HMM: 1-364/364
Sequence Identity: 20% (75 aa)

IGKGGFAVVVLGVNPKTQ--------KQVAIKIISREEVTKRN------------------------LMQYLENELRLSTRFDHPNVCKVLDVIYEEDI-
||.|||..|  |.   .         | ||.|....... ...                        ... .|.|...  |..|||... . .  ...  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------IMVVMEYFKNGD-LQSMLSNGVNFTYEQKCKISFDILQGINYLHKRD--------ISHRDIKPENVLLDDDFT--------------P
            .. |||| ..|. |  ..        .|.|... || .|.|||| ..        | |||.|..|.|.|...|              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KLIDFGLAKENGTS----------------------LHTYCGTPFYMAPEVIISDTYDGIKA---------------DIWAFGVTVHVLSTGKFPWY-VK
|. ||||.... .|                      ..| |||| .|||||.  ....  |.               |...||.    . |.. |.|  .
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

NDVQLIR-------ELQAN-KLELIIE------------PTG--VLGTLISKCLVFDSKKRSSSSDLLTLL
.. ....       .. .. .| . |             |.    .  |. .|   | .|| | ...|  |
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase 95537.m00095.AA QIK 22-226 34 2e-53 183.84 In-house 1-226 (272) Show / Hide
Range on Protein: 22-226
Range on HMM: 1-226/272
Sequence Identity: 34% (79 aa)

YRVVRTIGKGGFAVVVLGVNPKTQKQVAIKIISREEVTKRNLMQYLENELRLSTRFDHPNVCKVLDVIYEEDIIMVVMEYFKNGDLQSMLSN--------
| . |||||| |||| |. .  | ..|||||| ..  .. ||   .. |  .  . .||.. | ..|.  .| . .|.|| .||..   | .        
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQK-CYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

------------GVNFTYEQKCKISFDILQGINYLHKRDISHRDIKPENVLLDDDFTPKLIDFGLA--KENGTSLHTYCGTPFYMAPEVIISDTYDGIKA
            ||  . ..  ..  .|. .. |.||| | |||.| ||.||| .   |..|||.    ..|  | |.||.| | |||.     ||| |.
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DIWAFGVTVHVLSTGKFPWYVKNDVQL
|||  ||   || .|..|   |.. .|
DIWSMGVVLYVLVCGALPFDGKTLQNL

Kinase 95537.m00095.AA STE 22-267 23 1.8e-45 157.41 In-house 1-352 (359) Show / Hide
Range on Protein: 22-267
Range on HMM: 1-352/359
Sequence Identity: 23% (84 aa)

YRVVRTIGKGGFAVVVLGVNPK---------------TQKQVAIKIISREEVTK--------------RNLMQYLENELRLSTRFD--HPNVCKVLDVIY
.. .. ||||.| .|....| |               |.. .|||... |. ..               . || ...|...  ...  |||. | ..  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EE-------DIIMVVMEYFKNGDLQSMLSN--GVNFT------------YEQKCKISFDILQG-INYLHKRDISHRDIKPENVLLDDDFTPKLIDFGLAK
 |       | . ..|||  .| | ... .  |....             .| ..| ..||.|  .|||.  | |||||| |.||      ||.|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

-------------------ENGTSLHTYCGTPFYMAPEVIIS-----DTYDGIKADIWAFGVTVHVLSTGKFPWYVKNDVQLIRELQAN-----------
                    ..    | .||| .||||||       |   ..|.||| .| |.  . ||| ||   .. . . . . |           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---KLELIIEPT---------------------GVLGTLISKCLVFDSKKRSSSSDLL
   .    ....                       .   |.|||. | .|| ..|.||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLL

Kinase 95537.m00095.AA MARK 129-218 46 2.5e-39 126.35 In-house 113-206 (262) Show / Hide
Range on Protein: 129-218
Range on HMM: 113-206/262
Sequence Identity: 46% (44 aa)

ILQGINYLHKRDISHRDIKPENVLLDDDF--TPKLIDFGLAKEN--GTSLHTYCGTPFYMAPEVIISDTYDGIKADIWAFGVTVHVLSTGKFPW
|. ..||.|...| ||||||||.|.|..     |.||||.. .   |. | | |||| |||||.. .  ||| |.|||. ||   .. .|.||.
IVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPF

Kinase 95537.m00095.AA TyrKc 22-270 20 1.4e-31 112.17 SMART 1-280 (280) Show / Hide
Range on Protein: 22-270
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

YRVVRTIGKGGFAVVVLGVNPKTQKQVAIKIISREEVTKRNLMQYLENELRLSTRF--DHPNVCKVLDVIYEE-------DIIMVVMEYFKNGDLQSML-
 .  ...| | | .|..|.      |||.| .  .       .. . .|.|. ...  .|||. . . |. ..       . .|.|||| ..|||.. | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SNGVNFTYEQKCKISFDILQGINYLHKRDISHRDIKPENVLLDDDFTPKLIDFGLAKENGTS-------LHTYC----GTP-----FYMAPEVIISDTYD
... ... .........| .| .|||.. . |||.   |.|.....| |  ||||... .                  |.        ||||.|   .. 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GIKADIWAFGVTVH-VLSTGKFPWYV-----KNDVQLIRELQANKLELIIEP---------TGVLGTLISKCLVFDSKKRSSSSDLLTLL
 .| |.|.|||.   ... |. |..      ... ..|. ... .   . .          .  . .....|  .| ..| . |..  ..
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 95537.m00095.AA Pkinase_Tyr 22-219 24 1.5e-22 77.04 Pfam 1-217 (270) Show / Hide
Range on Protein: 22-219
Range on HMM: 1-217/270
Sequence Identity: 24% (54 aa)

YRVVRTIGKGGFAVVVLGVNP----KTQKQVAIKIISREEVTKRN-LMQYLENELRLSTRF-DHPNVCKVLDVIY-EEDI--IMVVMEYFKNGDLQSMLS
 .  ...|.| | .|..|.      .|. .||.|.. .|  .... ... . .|... . . .|||. . . |.. ...   |..|||| ..||| . | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

N----GVNFTYEQKCKISFDILQGINYLHKRDISHRDIKPENVLLDDDFTPKLIDFGLAKEN-------GTSLHTYCGTPFYMAPEVIISDTYDGIKADI
.    . ..| .........| .| .||. . . |||.   |.|...... |  |||||.          .. ..     . ||||.|    .  .| |.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFT-TKSDV

WAFGVTVHVLST-GKFP-WY
|.|||.   . | |. | ..
WSFGVLMWEIFTYGEQPTYP

Kinase 95537.m00095.AA MARK 22-109 32 2.1e-22 70.17 In-house 1-91 (262) Show / Hide
Range on Protein: 22-109
Range on HMM: 1-91/262
Sequence Identity: 32% (30 aa)

YRVVRTIGKGGFAVVVLGVNPKTQKQVAIKIISREEVTKRNLMQYLENELRLSTRFDHPNVCKVLDVIY--EEDI-IMVVMEYFKNGDLQS
|....|||.|..|.| |... .|...|||||. ..  .. . |. .. |...  . ||||. | ..||   .|   | ..|||  .|.| .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYD