Gene 83711.m00163 (T.vaginalis)

83711.m00163

Species: T.vaginalis
Alias: 83711.m00163, TvagK0030
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
83711.m00163.AA Protein None 357 None Fasta, JSON
83711.m00163.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 83711.m00163.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 83711.m00163.AA CAMKL 27-279 34 1e-99 318.9 In-house 1-297 (297) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-297/297
Sequence Identity: 34% (104 aa)

YRVVKVINHGSFSVVCLVENIRT-LQQYACKIVSRQTLRENETIQHF------------EQEIRFHQSLK---HKNICQLYEIVYEQDF------IFLIM
||..|.. .|||..| | ..|||  ...| ||. .. ..... ..              ..||. ...|.   |.||..|||... ...      |.|.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCANGE--LFELITKR----ARLPQYQIRKYFSQLVAAVNYIHSKNIAHRDLKLENIYLTEDMD--IRLGDFGFS---HS--TEKQALLSTSCGSIYYV
||| .||  ||. | |.     |.|  . |.|| |.|.||||.||..|.|||.|.||| |.|...  | . |||||         .  .|.|.|||  | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVIRG--EQYDGQKSDIWSLGVILYIMSTSALPWTEQ--------NQSRLFQQIVSASYKIPQF--VSPEAGNIIQSCLNPIPSKRPSAADLMSSSYV
|||.. |  ..|||.| ||||.||||| | . .||. ..        |. .|. .| .  |..| .  || .. ..|.. |.. |.|||.. ..|.   .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 83711.m00163.AA CAMK 32-279 21 1.4e-99 321.56 In-house 1-425 (425) Show / Hide 
Range on Protein: 32-279
Range on HMM: 1-425/425
Sequence Identity: 21% (92 aa)

VINHGSFSVVCLVENIRTL------------QQYACKIVSRQTLRENE-------------------------TIQHFEQEIRFHQS-------LKHKNI
.. .|||..| |.....|             |..|.||.... |....                         . . ...||. ...       |.|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

CQLYEIVYE-------------------QDFIFLIM---EYCANGEL----FELITKR---------------ARLPQYQIRKYFSQLVAAVNYIHSKNI
..|||.                      .......|   ||| .|||    |. |...                |..  . |.|| |.. ||.|.||.||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDLKLENIYLTEDM-----------------DIRLGDFGFSHSTEKQA------------------------LLSTSCGSIYYVA-PEVIRG------
.|||||.||| |....                 .| . ||||.   ..                          ...|.||. .|.| |||..|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------EQYDGQKSDIWSLGVILYIMSTSALPWTEQ-------------NQSRLFQQIVSASYK-IPQF-----------------------VSPEAGN
       ..|.|.|.|.||.||||||| .  .|. .              |...||..| .. |  .| .                       ||.|. .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

IIQSCLNPIPSKRPSAADLMSSSYV
 |...|.. |.||..... ..   .
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 83711.m00163.AA AMPK 27-279 37 4e-93 276.8 In-house 1-254 (254) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-254/254
Sequence Identity: 37% (94 aa)

YRVVKVINHGSFSVVCLVENIRTLQQYACKIVSRQTLRENETIQHFEQEIRFHQSLKHKNICQLYEIV-YEQDFIFLIMEYCANGELFELITKRARLPQY
| . | |  |.|  | . . |.| .. | ||  .| ... .. .  . ||.  ....| .| ||||..   .. ||..||| ..||||. |.|. ||.  
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

QIRKYFSQLVAAVNYIHSKNIAHRDLKLENIYLTEDMDIRLGDFGFSHSTEKQALLSTSCGSIYYVAPEVIRGEQYDGQKSDIWSLGVILYIMSTSALPW
. ...| | ...| |.|  .|.|||||.||. | ... | . ||| |   ..  .|.|.|||  | |||.| |  | | . |||| ||||| |    || 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

TEQNQSRLFQQIVSASYKIPQFVSPEAGNIIQSCLNPIPSKRPSAADLMSSSYV
 ..|.. |.. |..  |.||.|.|||| ..|.. |.. | || .  |.. ... 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 83711.m00163.AA MARK 27-279 37 5.1e-91 297.75 In-house 1-262 (262) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-262/262
Sequence Identity: 37% (98 aa)

YRVVKVINHGSFSVVCLVENIRTLQQYACKIVSRQTLRENETIQHFEQEIRFHQSLKHKNICQLYEIVY--EQDF-IFLIMEYCANGELFELITKR--AR
|...|.| |||...| |. ...| ...| ||. .. | ...... .. ||. ...|.|.|| .|....   .    |.|||||. .|||.. | ..   |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LPQYQIRKYFSQLVAAVNYIHSKNIAHRDLKLENIYLTEDM--DIRLGDFGFSHSTEKQALLSTSCGSIYYVAPEVIRGEQYDGQKSDIWSLGVILYIMS
|.    |..|.|.| |||| |||||.|||.|.||| . |..  .| . |||||   .   .|.| ||.  | |||.. .. |||.| |||||||.||.| 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TSALPWTEQN--QSRLFQQIVSASYKIPQFVSPEAGNIIQSCLNPIPSKRPSAADLMSSSYV
.  .|. ...  .  |...|.. .|.|| .||.|. |.||. |.. |..||.. ..|. . .
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 83711.m00163.AA Pkinase 27-279 27 3.3e-89 307.47 Pfam 1-293 (293) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-293/293
Sequence Identity: 27% (82 aa)

YRVVKVINHGSFSVVCLVENIRTLQQYACKIVSRQTLRENETIQHFE-QEIRFHQSLKHKNICQLYEIVYEQDFIFLIMEYCANG----ELFELIT--KR
|.....|  |||..|..  .. | ...|.||..... .... ..|.  .||. ...|.|.||..||..... | | ..|||| .|    .||..|.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

ARL--PQYQIRKYFSQLVAAVNYIHSKNIAHRDLKLENIYLTEDMDI----RLGDFGFSHS--TEKQALLSTSCGSIYYVAPEVIRGEQYDGQKSDIWSL
 ..  .  ....|. |.. ...|.||..| |||||.||| . ....|    ...|||..    . ..  ..| ||...|.||||||| ||.|.|.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYIMSTSALPWTEQ------NQSRLFQQIVSASYKIPQFVS---------------------PEAGNIIQSCLNPIPSKRPSAADLMSSSYV
|.|||.| .  .|. ..      .|  ....| .. .. . . .                     .|.  .| .||.. |.|||.|.... . ..
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 83711.m00163.AA S_TKc 27-279 31 1.3e-87 298.28 SMART 1-231 (231) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

YRVVKVINHGSFSVVCLVENIRTLQQYACKIVSRQTLRENETIQHFEQEIRFHQSLKHKNICQLYEIVYEQDFIFLIMEYCAN--GELFELITKRAR---
|.....| .|.|..|... ...| ...|.||..          .|...||. ... .|.||..||.. .. |.....|||| .  |.||..| || |   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LPQYQIRKYFSQLVAAVNYIHSKNIAHRDLKLENIYLTEDMDIRLGDFGFSHSTEKQALLSTSCGSIYYVAPEVIRGEQYDGQKSDIWSLGVILYIM
   .|  ..|.|. |.. |..|.||..| ||||| ||| |.|   | ..|||..         .| ||. .|.||||.   .|.. |.|.||.|.|||.|
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

STSALPWTEQNQSRLFQQIVSASYKIPQFVSPEAGNIIQSCLNPIPSKRPSAADLMS-------SSYV
 .   |.   .. ..|..|.          |||| ..|. ||.  |.|||.| ...          ..
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 83711.m00163.AA Ciliate-E2 27-279 22 2e-69 236.94 In-house 1-365 (365) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-365/365
Sequence Identity: 22% (85 aa)

YRVVKVINHGSFSVVCLVENIRT-----------------------LQQYACKIVSRQTLRENETIQHFEQEIR----------FHQSLKHKNICQLYEI
| ..|.|  |.|..|........                        ..|| ||.. . ... . ..|  .||.            ..|.|.||...|| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VY--EQDFIFLIMEYCANGELFELITKR-----------ARLPQYQIRKYFSQLVA---------------AVNYIHSKN-IAHRDLKLENIYLTEDMDI
 .   .. |.|.||||  |.||..| ..            ..  ..|.... |..                |..|.|||| | |||.|.||| .     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RLGDFGFS-HSTEK-------------------------------QALLSTSCGSIYYVAPEVIRGEQYDG--------QKSDIWSLGVILYIMSTSALP
 . |||.|   ...                               | .  | ||. .|.|||...|..||.         |.||||||||||.| .  .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WTEQNQSRLFQQIVSASYKIPQF------------------VSPEAGNIIQS----CLNPIPSKRPS-AADLMSSSYV
.        .|||    ...|..                  .|.|. ..|.     .|.  |.||.. . ...   . 
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 83711.m00163.AA QIK 27-267 35 3.2e-68 232.95 In-house 1-260 (272) Show / Hide 
Range on Protein: 27-267
Range on HMM: 1-260/272
Sequence Identity: 35% (92 aa)

YRVVKVINHGSFSVVCLVENIRTLQQYACKIVSRQTLRENETIQHFEQEIRFHQSLKHKNICQLYEIVYEQDFIFLIMEYCANGELFELITKRAR-----
| . . |  | | || |  .. | .. | ||. .  | | . .|  . |.    .|.| .|  ||..   .| .....||| |||.|. ..|  |     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEEN-LQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LPQYQIRKYFSQLVAAVNYIHSKNIAHRDLKLENIYLTEDMDIRLGDFGFSHSTEKQALLSTSCGSIYYVAPEVIRGEQYDGQKS
               ..  . |. |.|...|| | |..||.||||| ||| | ..|.| . |||||   .. .||.| |||  | |||.  |..||| |.
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DIWSLGVILYIMSTSALPWTEQNQSRLFQQIVSASYKIPQFVSPEAGNIIQSCLNPIPSKR
||||.||.||.. . |||   ..   | | ..|  ..|| |.| .   .|   |   |..|
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHR
Kinase 83711.m00163.AA CAMK-Unique 27-279 23 4.2e-68 223.86 In-house 1-363 (363) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-363/363
Sequence Identity: 23% (87 aa)

YRVVKVINHGSFSVVCLVENIRTLQQYACKIVSRQTLRENETIQ-----------------HFEQEIRFHQSLKHKNICQLYEI----VYEQD-------
|. ...| ||.|..|  . .. |   .|||.|  ||  ..  .|                  .. |..  ....| || .||..    .   .       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------FIFLIMEYCANGELFELITK--------------------RARLPQ--YQIRKYFSQLVAAVNYIHSKNIAHRDLKLENIYLTED-------
         ....||||  |.||..| |                    . ..    .... .. .|. ||.| ||..| ||||||||| . .        
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

---------MDIRLGDFGFSHSTE-KQAL--LSTSCGSIYYVAP--------------EVIRGEQYDGQKS---DIWSLGVILYIMSTSALPWTEQNQS-
          .| | ||| .   . ...   ..| ||...|.||              ||| .  ||.| |   ||||||||.|.| .  .| ....   
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------RLFQQIVSASY--------KIPQFVSPEAGNIIQSCLNPIPSKRPSAADLMSSSYV
       ..|. | .. |         .| ..|.|| .... |.. .|..| ||. | .....
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 83711.m00163.AA MELK 27-279 37 8e-67 227.33 In-house 1-254 (254) Show / Hide 
Range on Protein: 27-279
Range on HMM: 1-254/254
Sequence Identity: 37% (96 aa)

YRVVKVINHGSFSVVCLVENIRTLQQYACKIVSRQTLRENETIQHFEQEIRFHQSLKHKNICQLYEIVYEQDFIFLIMEYCANGELFELITKRARLPQYQ
| | . |  | |. | |   | | |. | ||. ...| ..  .   . |.   ..|.|..||||| ..  .| ||..||||. ||.|. | .. || . .
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGHD--LPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEE

IRKYFSQLVAAVNYIHSKNIAHRDLKLENIYLTEDMDIRLGDFGFSHST--EKQAL-LSTSCGSIYYVAPEVIRGEQYDGQKSDIWSLGVILYIMSTSAL
 |..| |.|.|. |.||.  |||||| ||. ..||. ..| |||.   |  .|    | | |||  | |||.|.| || |   |.||.|..||..   .|
TRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PWTEQNQSRLFQQIVSASYKIPQFVSPEAGNIIQSCLNPIPSKRPSAADLMSSSYV
|. . | . ....|.|  |. |...|||. ....  |   | || |  .|.   .|
PFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 83711.m00163.AA ULK 27-267 24 2.6e-66 226.62 In-house 1-317 (329) Show / Hide 
Range on Protein: 27-267
Range on HMM: 1-317/329
Sequence Identity: 24% (77 aa)

YRVVKVINHGSFSVVCLVENIRT----LQQYACKIVSRQTLRENE-------TIQHFEQEIRFHQSLK----HKN----ICQLYEIVYEQDF--IFLIME
| . ... .||| .|.  .|..|     ...|||....|......        .| ...||.  . ||    |||    |..||.. .....  |..|||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCANGELFELITKRAR----------LPQYQIRKYFSQLVAAVNYIHSKNIAHRDLKLENIYLTED------------MDIRLGDFGFSHSTE-----KQ
||  | |...| |. .          |.. .....| |....  ..|..|| |||.|..|| ....            . . ..||||. . .     .|
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

ALLSTS-----CGSIYYVAPEVIR----GEQYDGQKSDIWSLGVILYIMSTSALP---WTEQNQS-----RLFQQ-------IVSASYKIP-----QFVS
 .....     ||. .| ||...     ...|.  |.||||||.|.| | .   |   |  . |      .|...       | .   ..|     . .|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PEAGNIIQSCLNPIPSKR
||  ..|. .|   ...|
PECKDLIRRMLQYDEKDR
Kinase 83711.m00163.AA ULK 27-267 24 9.9e-66 224.68 In-house 1-312 (324) Show / Hide 
Range on Protein: 27-267
Range on HMM: 1-312/324
Sequence Identity: 24% (76 aa)

YRVVKVINHGSFS-VVCLVENIRT---LQQYACKIVSRQTLRENET-------IQHFEQEIRFHQSLK---HKN--ICQLYEIVYEQDF--IFLIMEYCA
| . ... .|||  .|.  .|..|    |..|||..... .....        .| ...||.  . ||   |.|  |..||.. .....  |..||||| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGELFELITKRAR---------LPQYQIRKYFSQLVAAVNYIHSKNIAHRDLKLENIYLTED------------MDIRLGDFGFSHSTEK----QALLST
 | |...| |. .         |.. .....| |....  ..|..|| |||.|..|| ....              . ..||||. . ..    | .. |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

SC------GSIYYVAPEVIR----GEQYDGQKSDIWSLGVILYIMSTSALP---WTEQNQS----RLFQQ-------IVSASYKIP-----QFVSPEAGN
 .      |. .| ||...     ...|.  |.||||||.|.| | .   |   |  ..|     .| ..       |     ..|     . .|||  .
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

IIQSCLNPIPSKR
.|. .|   ...|
LIRRMLQYDEKDR
Kinase 83711.m00163.AA TyrKc 27-277 21 2.8e-16 40.42 SMART 1-280 (280) Show / Hide 
Range on Protein: 27-277
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

YRVVKVINHGSFSVVCLVENIRTLQQYACKIVSRQTLRENETIQHFEQEIRFHQSL--KHKNICQLYEIVYEQ-------DFIFLIMEYCANGELFELIT
 .  |.. .| | .|.. . .   .| | | .   .      .. | .|.|   .|  .|.|| .|| .. .|       . ....|||...| | . . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KRAR-LPQYQIRKYFSQLVAAVNYIHSKNIAHRDLKLENIYLTEDMDIRLGDFGFSHSTEKQ-------ALLSTS---CGS----IYYVAPEVIRGEQYD
|. . |.  .  ..  |  .  .|.||||. ||||   |. ..|.  .. .||| |   .            ...   .|     |   |||.|   .| 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NYG

--GQKSDIWSLGVILY-IMSTSALPWTE-----QNQSRLFQQIVSASYKIPQFV---------SPEAGNIIQSCLNPIPSKRPSAADLMSSS
    |||.|| || .. |..  . |. .      . ....... .  .  .            ..|  .|...| .  |..||. ... .  
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 83711.m00163.AA Pkinase_Tyr 62-170 27 4.2e-09 31.46 Pfam 35-156 (270) Show / Hide 
Range on Protein: 62-170
Range on HMM: 35-156/270
Sequence Identity: 27% (33 aa)

TLRENETIQH-----FEQEIRFHQSL-KHKNICQLYEIVY-EQDF--IFLIMEYCANGELFELITK----RARLPQYQIRKYFSQLVAAVNYIHSKNIAH
.|.|. . ..     | .|..   .| .|.|| .|| ... ...   |...|||...| | .   |    . .|.  .. ..  |  .. .| .|||. |
MLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIH

RDLKLENIYLTEDMDIRLGDFG
|||   |. .||.. .. .|||
RDLAARNCLVTENNVVKICDFG
Kinase 83711.m00163.AA Pkinase_Tyr 205-275 22 0.030441 8.22 Pfam 194-268 (270) Show / Hide 
Range on Protein: 205-275
Range on HMM: 194-268/270
Sequence Identity: 22% (17 aa)

KSDIWSLGVILY-IMSTSALP-WTEQNQSRLFQQIVSASYKIPQFV--SPEAGNIIQSCLNPIPSKRPSAADLMS
|||.|| || .. |..  . | . .   ......|    |  |.    ..|  .....| .. |..||. ... .
KSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHE