Gene 91798.m00162 (T.vaginalis)

91798.m00162

Species: T.vaginalis
Alias: TvagK0686, 91798.m00162
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
91798.m00162.AA Protein None 388 None Fasta, JSON
91798.m00162.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 91798.m00162.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 91798.m00162.AA NEK 4-259 40 4.5e-127 428.47 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-286/286
Sequence Identity: 40% (117 aa)

YRVDKVLGKGGFGKALLVTSLENESK----KRVVKQIILSKLSEKQQLKAE-SEITILSTLKHTNIVRYRGCKKTKS--SLFILMDYAD-GGDLQQL---
|.. |..|.| |||. .| . .....    . | |.| ....|||.. .|  .|. ||. ||| |||.|. .   .   .|.| |.|.. ||||.|.   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

LKRRN--LSSIPEDKIIDWFTQICLAVKYIHDR-----KIIHRDIKPSNIFLDSNGV----LKLGDFGLARFLDSTEAFAAT-FAGSPYYMPPEICNVQK
.|..      ..|..| |||.|.|||.||.|||     ||.||||||.||||..|.     .|.||||... |..|  .| | . | |||| ||.|. ..
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP

YNASADIWSLGCVLYEMCNL--RKAFYGI--NVHNIMLDITRN-TPSKIRSF--YSKELSDLVSSMLNKDPQLRPTINEILQIPII
||  .||||||||||||| |  ...|..   | .. .. |... ....| |.  ||..|..|.|.||.|||..||..|.||. |.|
YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 91798.m00162.AA NEK1 4-259 44 1.9e-109 369.9 In-house 1-276 (276) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-276/276
Sequence Identity: 44% (122 aa)

YRVDKVLGKGGFGKALLVTSLENESKKRVVKQIILSKLSEKQQLKAESEITILSTLKHTNIVRYRGCKKTKSS--LFILMDYADGGDLQQLLKRR--NLS
| . |..|.| ||||.||.. | ...  | | | ..| .||   ..  |  ||. .|| |||.|.       .  |.| |.|.||||| |  .|.     
YHYIKQIGEGSFGKAWLVKHKE-DGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGK

SIPEDKIIDWFTQICLAVKYIHDRKIIHRDIKPSNIFLD--SNG---------------VLKLGDFGLARFLDSTEAFAATFAGSPYYMPPEICNVQKYN
...|| | .||.|||||...||||||.|||||..||||   .||               ..|||||| || | .| ..| | .| ||| .||||. . ||
LFSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYN

ASADIWSLGCVLYEMCNLRKAFYGINVHNIMLDITRNTPSKIRSFYSKELSDLVSSMLNKDPQLRPTINEILQIPII
   ||||||||||| | |  .| . | .|  | |.. | ..| . ||.||. |||.|....|..|| .| ||. |.|
NKSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase 91798.m00162.AA NEK8 4-259 35 1.2e-93 267.73 In-house 1-278 (278) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-278/278
Sequence Identity: 35% (99 aa)

YRVDKVLGKGGFGKALLVTSLENESKKRVV-KQIILSKLSEKQQLKAESEITILSTLKHTNIVRYRGCKKTKSSLFILMDYADGGDLQQLLKRRNLSSIP
|    |.|.| || . |    |  | . |. ||| .. .|||.   | .|| .|| | | ||. | .      .|.| | ||||| | |.. ..  ..  
YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQHQQNKLFE

EDK-----------------IIDWFTQICLAVKYIHDRKIIHRDIKPSNIFLDSN-GVLKLGDFGLARFLDSTEAFAAT---FAGSPYYMPPEICNVQKY
| .                 |.. |.|.|.|| ..|.  | |||.|. |||..   .|.|.||||..  . .|.  ..|     | |||| ||.|  ..|
EERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIM-NTKYHMQTTKTVVGTPYYMSPEMCEGKPY

NASADIWSLGCVLYEMCNLRKAFYGINVHNIMLDITRN-TPSKIRSFYSKELSDLVSSMLNKDPQLRPTINEILQIPII
|.  |.|.||||||||| |..|| . |  .. . |..  .   | . ||.|.  ||.. | .||. ||.  .|.  | .
NQKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase 91798.m00162.AA S_TKc 4-259 32 2.1e-87 297.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-231/231
Sequence Identity: 32% (88 aa)

YRVDKVLGKGGFGKALLVTSLENESKKRVVKQIILSKLSEKQQLKAESEITILSTLKHTNIVRYRGCKKTKSSLFILMDYADG--GDLQQLLKRRNL---
|.. ...|||.|||  ...  .   ..  .|.|           ....|| ||.  .| |||.. ..  . ..|.. |.|.||  ||| ...|.|.    
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-SSIPEDKIIDWFTQICLAVKYIHDRKIIHRDIKPSNIFLDSNGVLKLGDFGLARFLDSTEAFAATFAGSPYYMPPEICNVQKYNA-SADIWSLGCVLYE
 . .||  .  .. |||.|..|.|...|||||.||.||.||.  ..|..||||||.|        || |.|.||.||..   .|.  ..|.||.||.|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MCNLRKAFYGINVHNIMLDITRNTPSKIRSFYSKELSDLVSSMLNKDPQLRPTINEILQ-------IPII
|.  .  |.    .. |... .          |.|. |... .|.|||. |||. |.||        | .
MLCGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 91798.m00162.AA Pkinase 4-259 29 7.2e-80 276.44 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-293/293
Sequence Identity: 29% (87 aa)

YRVDKVLGKGGFGKALLVTSLENESKKRVVKQIILSKLSEKQQLKAES--EITILSTLKHTNIVRYRGCKKTKSSLFILMDYADGG----DLQQLLK---
|.. ...|.|.||.  . .   ..  . .||.| ... .....  .    || |.  |.| ||||....  .|... . |.|..||    ||  ...   
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

RRNLSSIPEDKIIDWFTQICLAVKYIHDRKIIHRDIKPSNIFLDSNGVL----KLGDFGLARFL-DSTEAFAATFAGSPYYMPPEICN-VQKYNASADIW
.....  .|. ......||. ...|.|...|||||.||.||..|.||..    |..|||||...       . ||.|.|.||.||...  |.|  ..|.|
HGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGCVLYEMCNLRKAFYGI----NVHNIMLDITRNTPSKIRSFYS-----------------------KELSDLVSSMLNKDPQLRPTINEILQIPII
|.||.||||.. |  |.|     | |. |  | |. . .... ..                       .|. |.....|.|||. |||. .||| | .
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 91798.m00162.AA ULK 4-259 27 7.6e-80 271.58 In-house 1-329 (329) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-329/329
Sequence Identity: 27% (92 aa)

YRVDKVLGKGGFGKALLVTSLENE---SKKRVVKQIILSKLSEKQQL--------KAESEITILSTLK--------HTNIVRYRGCKKTK--SSLFILMD
| ....|||| |||    .  ...    .| ..|.| ..|...|...          ..|| |. .||        | |||..  ...|.    ..| |.
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YADGGDLQQLLKRRNL--------SSIPEDKIIDWFTQICLAVKYIHDRKIIHRDIKPSNIFLDSN------------GVLKLGDFGLARFLDST---EA
| .||||.|..|...           ..|...|  | ||. . |..|...||||||||.|| .. .            ||||..|||.|...|.    ..
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

FAATFA------GSPYYMPPEICN----VQKYN-ASADIWSLGCVLYEMCNLRKAFYG-INVHN---IMLDITR---------NTPSKIR-----SFYSK
 . |.       |.|.|| |.| .     ..|. . .|||||||..|||   .  ||. .|  .   |.  |           ..| ...        |.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

ELSDLVSSMLNKDPQLRPTINEILQIPII
|. || . || .|.  | .. |....|..
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 91798.m00162.AA ULK 4-259 28 2.4e-78 266.57 In-house 1-324 (324) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-324/324
Sequence Identity: 28% (91 aa)

YRVDKVLGKGGFG-KALLVTSLENE--SKKRVVKQIILSKLSEKQQL--------KAESEITILSTLK---HTN--IVRYRGCKKTK--SSLFILMDYAD
| ....|||| || |    .  ...   ..  .|.| ..|...|...        . ..|| |. .||   | |  ||..  ...|.    ..| |.| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLQQLLKRRNL-------SSIPEDKIIDWFTQICLAVKYIHDRKIIHRDIKPSNIFLDSN------------GVLKLGDFGLARFLDSTE---AFAAT
||||.|..|...          ..|...|  | ||| . |..|...||||||||.|| .  .            ||||..|||.|...|. .       |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

FA------GSPYYMPPEICN----VQKYN-ASADIWSLGCVLYEMCNLRKAFYG-INVHNI-MLDI----------TRNTPSKIR-----SFYSKELSDL
.       |.|.|| |.| .     ..|. . .|||||||..|||   .  |.. .|  .. . .            .|.| ...        |.|. ||
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

VSSMLNKDPQLRPTINEILQIPII
 . || .|.  | .. ||...|..
IRRMLQYDEKDRISWEEIFNHPWF
Kinase 91798.m00162.AA NEK4 4-259 38 5.3e-78 265.46 In-house 1-257 (257) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-257/257
Sequence Identity: 38% (100 aa)

YRVDKVLGKGGFGKALLVTSLENESKKRVVKQIILSKLSEKQQLKAESEITILSTLKHTNIVRYRGCKKTKSS--LFILMDYADGGDLQQLLKRRNLSSI
|   || ||| .|   || .     |. |.| . | . | ...  || |. .|| ||| ||| |    .      |.| | . .|||| . ||..    .
YCHMKVVGKGSYGEVWLVRH-RRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQFL

PEDKIIDWFTQICLAVKYIHDRKIIHRDIKPSNIFLDSNGVLKLGDFGLARFLDSTEAFAATFAGSPYYMPPEICNVQKYNASADIWSLGCVLYEMCNLR
.|  ...|| || .|  |.|...|.||| |  ||||    ..|.||||..| |.    .| |  | |||| ||.   . |.   ||||||| .|||  |.
EEYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITLK

KAFYGINVHNIMLDITRNTPSKIRSFYSKELSDLVSSMLNKDPQLRPTINEILQIPII
 ||   .   ..  |    |  .   ||..| .||  ||.| |. || | .|.| | |
HAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase 91798.m00162.AA Ciliate-E2 4-259 22 3.7e-72 246.04 In-house 1-365 (365) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-365/365
Sequence Identity: 22% (86 aa)

YRVDKVLGKGGFG-----KALLVTSLE-----------------NESKKRVVKQIILSKLSEKQQLKAES-EIT----------ILSTLKHTNIVRYRGC
| . |..|.|.||     |  .|  ..                 . .|.  .|... ... .. | . .  ||           ||..|.| ||...  |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

KK--TKSSLFILMDYADGGDLQQLLKRRNLSS---------IPEDKIIDWFTQICL---------------AVKYIHDRK-IIHRDIKPSNIFLDSNGVL
 .  ....... |.|..||||....| .....         . | .|.. ..||.                |..|.| .. ||||||||.||..     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLGDFGLARFLDS-------------------------------TEAFAATFAGSPYYMPPEICNVQK---------YNASADIWSLGCVLYEMCNLRKA
|. ||||....|                                 .  . |..|.|.||.||| | .|         |. ..||||||..||||.  .  
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FYGINVHNIMLDITRNTPSKIRSF------------------YSKELSDLVSS----MLNKDPQLRPT-INEILQIPII
|         ...  . . .....                   |.|  || .     ||.|||. |.| ...||. |..
F---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 91798.m00162.AA Ciliate-E2-Unclassified 4-259 24 3.8e-69 236.05 In-house 1-352 (352) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-352/352
Sequence Identity: 24% (88 aa)

YRVDKVLGKGGFGKALLVTSLEN----------ESKKRVVKQIILSKLSEKQQLKAESEIT-------------ILSTLKHTNIVRYRGCKKTKSSLFIL
|.. |..|.|||||  ..   ..           .... .|||  ..  .....|.. ..              ||. ..| .||..  |...|  ..| 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MDYADGGDLQQLLK-------------RRNLS--SIPEDKII-----DWFTQICLAVKYIHDRK-IIHRDIKPSNIFLDSNG---VLKLGDFGLARFLDS
|.|..||||.| .|             .....   ..| ...     ..| ||... .|.|  . ||||||||.||..|.||    .|. |||.......
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

T---------------EAFAATFAGSPYYM----PPEICNVQKYNAS----ADIWSLGCVLYEMCNLRKAFYGINVHN---------------IMLDITR
                .  . ||.|.|.||    .||.   |.|. |    .||||||..||||.  .  ||. |                  .....  
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

NTPSKIRSFY--------SKELSDLVS----SMLNKDPQLRPTINEILQIPII
. . ....|         |.|  |...    .||.|.|  |.|...||. |..
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 91798.m00162.AA CAMK 9-255 21 5.5e-69 221.2 In-house 1-421 (425) Show / Hide 
Range on Protein: 9-255
Range on HMM: 1-421/425
Sequence Identity: 21% (89 aa)

VLGKGGFGKALLVTSLENES-----------KKRVVKQIILSKLS--------------------------EKQQLKAESEITILST-------LKHTNI
.||.|.|||  |..  ..             .|  .| |  .||.                          .| . . ..|| |...       |.| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRYRGCKK------------TKSS--------LFILM---DYADGG----DLQQLLKRRNL-------------SSIPEDKIIDWFTQICLAVKYIHDRK
..                  | |         ... |   .|..||    || . ....                 ..|.    .| ||| ||.|.|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDIKPSNIFLDSN-----------------GVLKLGDFGLARFLDSTE-----------------------AFAATFAGSPYYMP-PEICN------
|.|||.|| || ||.|                 . .|. |||.|...|. |                           || |.|.||. ||. |      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------VQKYNASADIWSLGCVLYEMCNLRKAFYGI-------------NVHNIMLDITRNTPSKIRSFYSK-----------------------ELS
         . |. ..|.||.|..|| |   .  |||              | ....  |..   . . .. |.                       |  
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLVSSMLNKDPQLRPTINEILQ
||...||..||. |.|| ..|.
DLIRKMLQVDPEKRMTIEQCLN
Kinase 91798.m00162.AA NEK2 43-259 35 2.6e-67 225.68 In-house 41-319 (319) Show / Hide 
Range on Protein: 43-259
Range on HMM: 41-319/319
Sequence Identity: 35% (100 aa)

EKQQLKAESEITILSTLKHTNIVRY--RGCKKTKSSLFILMDYADGGDLQQLLK--RRNLSSIPEDKIIDWFTQICLAVKYIHD----------------
|.|.|   ||. ||. ||| |||||  .   ...|.| | | |  |||| |. |  |     ..|  |   ..|.|.| . .|                 
ECQML--VSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQYMEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKP

-----RKIIHRDIKPSNIFLDSNGV---------------------------------------LKLGDFGLARFLDSTEAFAATFAGSPYYMPPEICNV
     . |.|||||| |||||...                                         ||||||||| |     ||.|| | |||| ||  . 
RIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHG

QKYNASADIWSLGCVLYEMCNLRKAFYGINVHNIMLDITRNTPSKIRSFYSKELSDLVSSMLNKDPQLRPTINEILQIPII
||||   ||||.||..|||| |.  | . |       |     . | . ||..|......|.| |.. || |.|||| | |
QKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMINVDHYHRPSIEEILQHPQI
Kinase 91798.m00162.AA TyrKc 4-257 21 2.6e-22 81.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-257
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YRVDKVLGKGGFG---KALLVTSLENESKKRVVKQIILSKLSEKQQLKAESEITILSTL--KHTNIVRYRGCKKTK-------SSLFILMDYADGGDLQQ
 . .|.|| | ||   |. .         .  || .  ..     .    .|. |.. |  .| ||||  |.  ..         |.|.| |...|||..
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

LLKRRNLSSIPEDKIIDWFTQICLAVKYIHDRKIIHRDIKPSNIFLDSNGVLKLGDFGLARFLDST-------EAFAATF--AG---SPY-YMPPEICNV
 |...    .. .. ... .||.    |.|....||||.   |. ...|.. | .||||.|....        .   ..    |    |.  |.||  | 
YLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

QKYNASADIWSLGCVLYEMCNLRKAFYG------INVHNIMLDITRN-TPSKIRSFY-------SKELSDLVSSMLNKDPQLRPTINEILQIP
 |..   |.|| | ...|.. . .  |       ..   .. .. .   . .  . |       ..|. .. ..  . ||  ||| .|| .. 
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 91798.m00162.AA Pkinase_Tyr 51-158 28 6.1e-21 71.55 Pfam 52-165 (270) Show / Hide 
Range on Protein: 51-158
Range on HMM: 52-165/270
Sequence Identity: 28% (33 aa)

SEITILSTL-KHTNIVRYRGCKK-TKSS--LFILMDYADGGDLQQLLKRR--NLSSIPEDKIIDWFTQICLAVKYIHDRKIIHRDIKPSNIFLDSNGVLK
.|. |...| .| ||||. |.    . .  ..| | |. .|||   |...  .  ...   .... .||. .  | .....||||.   |. ...|.| |
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVK

LGDFGLARFLDSTE
 .|||||| . ...
ICDFGLARDIYNDD
Kinase 91798.m00162.AA Pkinase_Tyr 171-200 33 0.09802 6.5 Pfam 181-210 (270) Show / Hide 
Range on Protein: 171-200
Range on HMM: 181-210/270
Sequence Identity: 33% (10 aa)

MPPEICNVQKYNASADIWSLGCVLYEMCNL
|.||  |  |..   |.|| | ...|.. .
MAPECINYGKFTTKSDVWSFGVLMWEIFTY