Gene 91340.m00080 (T.vaginalis)

91340.m00080

Species: T.vaginalis
Alias: 91340.m00080, TvagK0601
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK7

Sequence

Name Sequence Type Origin Length Description Download
91340.m00080.AA Protein None 356 None Fasta, JSON
91340.m00080.kin_dom Protein Kinase Domain None 283 None Fasta, JSON

Protein domain

Protein domains of 91340.m00080.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 91340.m00080.AA CDK7 12-294 37 2.8e-99 265.04 In-house 1-288 (288) Show / Hide 
Range on Protein: 12-294
Range on HMM: 1-288/288
Sequence Identity: 37% (109 aa)

YRLLKTLGEGTFGVAYLARNLDTKEIVVLKKVK----IRGAEDGIDPQTIQELRQLCEMDHPNIVRYIGAFVNAGTVYIATEYVPFGLLDLIKSGPNQRP
|  .| .|||.|.. |.|. . | .||  ||.|       |.|||.   | |   | || |.|..  | .|     ..   .. .  |   ||   ..  
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKD--KSII

LSAADIKCIMRQFFSGLNYLHENWLLHRDLKPANMLVSESGILKLIDFGYSCDYPS-DSSDMGDAVTIWYKPPELLYGAKQVGPALDMWTAGCIFAELLL
|  |.|| .| .   || |.| || ||||||| | |..| |.||. |||    |.|        .||.||  ||||.||.. |.. |||  |||||||.|
LTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELML

CRPLFPGRTFGEVVQGITNLLG---PMVWPGCDHLPGYEQFKDIKPQNQIPPLEATFRGFSTDTLDLLSKLITIDPSKRISAADALMHPYF
  | .||       . | . ||   .  ||.   .. | .|||  .  .. ||.  |   | | |||.... | .|.||......| .|||
RVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRT-PLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase 91340.m00080.AA CDK 12-294 32 2.8e-93 298.81 In-house 1-284 (284) Show / Hide 
Range on Protein: 12-294
Range on HMM: 1-284/284
Sequence Identity: 32% (105 aa)

YRLLKTLGEGTFGVAYLARNLDTK-----EIVVLKKVKIRG-----AEDGIDPQTIQELRQLCEMDHPNIVRYIGAFVNA-----------GTVYIATEY
|  |. .||||.|| | ||...|.     .|| |||...       ...|.   .| |   | |. |||||. .  ..              ..|.  ||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

VPFGLLDLIKSGPNQRPLSAADIKCIMRQFFSGLNYLHENWLLHRDLKPANMLVSESGI-----LKLIDFGYSCDYPS------DSSDMG-DAVTIWYKP
..  |  ...            |||.|.|  .||.|.|.|| .||||||.| |... |.     ||. ||| .. . .       .  .    || || .
MDHDLKKYMD------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRA

PELLYGAKQVG--PALDMWTAGCIFAELLL---CRPLFPGRTFGEVVQGITNLLG---PMVWPGCDHLPGYEQFKDIKPQNQIPPLEATFRGFSTDTLDL
|||| |.|. .  .. ||| .||||||...    .|||||..  .    | ...|   . .|||. .||.|                           ||
PELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY---------------------------DL

LSKLITIDPSKRISAADALMHPYF
|.|. . ||.||||| .|| ||||
LNKMLCYDPKKRISAEQALQHPYF
Kinase 91340.m00080.AA CMGC 12-294 21 2.5e-89 293.59 In-house 1-513 (513) Show / Hide 
Range on Protein: 12-294
Range on HMM: 1-513/513
Sequence Identity: 21% (109 aa)

YRLLKTLGEGTFGVAYLARN--------------LDTKEIVVLKKVKIRG---------AEDGIDPQTIQELRQLCEM-----------------DHPNI
|  .| .||||.|| | .|.               .|.||| .||.| .          ..||.   .. |.. | ..                 .|.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VRYIGAFVNAG-----------------TVYIATEYVPFGLLDLIKSGP------NQRPLSAAD------------IKCIM------RQFFSGLN--YLH
|. .  |.  .                  .|. .||..  |...||. .      ...|||               ||..|      .| . ||.  |.|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

ENW--LLHRDLKPANMLVSES--------------------GILKLIDFGYSCDYPSDSSD----------------------MGDAVTIWYKPPELLYG
 .|   .||||||.| |...                     |.||..||| .. | . |..                        . || ||..||.| |
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

A---------KQVGPALDMWTAGCIFAELLLC--------RPLFPGRTF-----------GEVVQGITNLLG------------------PMVWPGCDHL
.         .. ... ||| .||||||...         .|||||..             .  . | ..||                  .  ||..  |
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

PGYEQ------------FKDI-----------KPQNQIPPLEATFRGFS-----------------------------------TDTLDLLSKLITIDPS
|.|..            ....           .|. . .|..  | ...                                    . .|||.|. ..||.
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

KRISAADALMHPYF
|||.|..|| ||||
KRITAEQALQHPYF
Kinase 91340.m00080.AA S_TKc 12-294 26 6.3e-86 292.68 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-294
Range on HMM: 1-231/231
Sequence Identity: 26% (78 aa)

YRLLKTLGEGTFGVAYLARNLDTKEIVVLKKVKIRGAEDGIDPQTIQELRQLCEMDHPNIVRYIGAFVNAGTVYIATEYVPF---GLLDLIKSGPNQRP-
|..|...|.|.||. |..|. .|..|| .|..|          ....|.. | . .|||||.....|.. . .|. .||..     |.|.||. . ... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSAADIKCIMRQFFSGLNYLHENWLLHRDLKPANMLVSESGILKLIDFGYSCDYPSDSSDMGDAVTIWYKPPELLYGAKQVGP-ALDMWTAGCIFAEL
  ..  .....|.| ...|.|.|... .||||||.| |..|   .|..||| .. .      .   .| || .||.|    . |. . |.|  |||..|.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEM

LLCRPLFPGRTFGEVVQGITNLLGPMVWPGCDHLPGYEQFKDIKPQNQIPPLEATFRGFSTDTLDLLSKLITIDPSKRISAADALM-------HPYF
|  .|.||       .| . ...|                                   | . .|...|. . ||.||..| .||        ||.|
LCGYPPFP------QMQMMFKKIG-----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 91340.m00080.AA Pkinase 12-294 28 5e-70 243.76 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-294
Range on HMM: 1-293/293
Sequence Identity: 28% (87 aa)

YRLLKTLGEGTFGVAYLARNLDTKEIVVLKKVKIRGAEDGIDPQTIQ--ELRQLCEMDHPNIVRYIGAFVNAGTVYIATEYVPFG-----LLDLIKSGPN
|......|.|.||. |.... .| .||..|..| |..... | . .   |.. . ...||||||....| . . .|. .||.. |     | |.|.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-WR

QRPL--SAADIKCIMRQFFSGLNYLHENWLLHRDLKPANMLVSESGIL----KLIDFGYSCD--YPSDSSDMGDAVTIWYKPPELLYGAKQVGPALDMWT
....  |  ..|..|.| ..||.|.|... .||||||.| |... | .    |..||| ..   | ..|  .. ..|.|| .||.. |..  ||. ||| 
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

AGCIFAELLLCRPLFPGR------TFGEVVQGITNLLGPMVWPGCDHLPGYEQFKDIKPQNQIPPLEATFRGFSTDTLDLLSKLITIDPSKRISAADALM
.|||..|.|. ||.|||.      .  .... |     .  ||  .  . .. |.. .     . ..      | . .|....... ||.||..|...| 
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQ

HPYF
||.|
HPWF
Kinase 91340.m00080.AA PITSLRE 12-294 34 1.9e-64 220.4 In-house 1-295 (295) Show / Hide 
Range on Protein: 12-294
Range on HMM: 1-295/295
Sequence Identity: 34% (104 aa)

YRLLKTLGEGTFGVAYLARNLDTKEIVVLKKVKIR--GAEDGIDPQTIQELR-QLCEMDHPNIVRYIGAFV--NAGTVYIATEYVPFGLLDLIKSGP-NQ
.  | . .|||.|| | |..  | ||| ||..|.      .|.    . |    | .. |||||      .  |   .|.. |||   | .|.      .
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

RPLSAADIKCIMRQFFSGLNYLHENWLLHRDLKPANMLVSESGILKLIDFGYSCDYPSD----SSDMGDAVTIWYKPPELLYGAKQVGPALDMWTAGCIF
 | .   ||| | |  .|  ..| || .||||| .|.| | .||||. |||    | |     .. .   || ||  |||| |.|   ...|||  ||||
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCV---VTLWYRAPELLLGCKKYSTPVDMWSVGCIF

AELLLCRPLFPGRTFGEVVQGITNLLGP---MVWPGCDHLPGYEQFKDIKPQNQIPPLEATFR---GFSTDTLDLLSKLITIDPSKRISAADALMHPYF
||... .|||.|.   . .. | ...|      |||   ||.   .......     |   |      |   .||| .. | .| .||.| ||| ||.|
AEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYP-YNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase 91340.m00080.AA CCRK 12-294 38 1.8e-63 217.14 In-house 1-285 (285) Show / Hide 
Range on Protein: 12-294
Range on HMM: 1-285/285
Sequence Identity: 38% (111 aa)

YRLLKTLGEGTFGVAYLARNLDTKEIVVLKKVKIRGAEDGIDPQTIQELRQLCEMDHPNIVRYIGAFVNAGTVYI-ATEYVPFGLLDLIKSGPNQRPLSA
| .|  .|||  |. . |. ..| ||| |||| .|  .|||  | . |.. | |..    |  . .    || .. . |..   | . ..    ||||. 
YCILDRIGEGAHGIVFKAKHVETGEIVALKKVALRRLDDGIPNQALREIKALQEIEDNQYVVQLKDVFPHGTGFVLVFEFMLSDLAEVVRH--AQRPLAE

ADIKCIMRQFFSGLNYLHENWLLHRDLKPANMLVSESGILKLIDFGYSCDYPSDSSDM--GDAVTIWYKPPELLYGAKQVGPALDMWTAGCIFAELLLCR
| .|  |.    |. . ||| ..||||||||.|.|||| ||. |||    .  | . .      | ||. |||||||.|     |.|. |||. |||   
AQVKSYMQMLLKGVAHCHENNIMHRDLKPANLLISESGHLKIADFGLARVFSNDEGRQYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCIMGELLNNS

PLFPGRTFGEVVQGITNLLG---PMVWPGCDHLPGYEQFKDIKPQNQIP-PLEATFRGFSTDTLDLLSKLITIDPSKRISAADALMHPYF
|.|||.   | .  .  .||   | |||.   || | .   |  . | | |||      | . |||| . .   | .||.|..||.|.||
PIFPGENDIEQLCCVLRILGTPTPKVWPEMKDLPDYNK---ISFKEQPPMPLEQVVPDASPQALDLLKQFLVYPPRQRIAASQALLHQYF
Kinase 91340.m00080.AA CDK10 12-294 35 1.5e-59 204.16 In-house 1-285 (285) Show / Hide 
Range on Protein: 12-294
Range on HMM: 1-285/285
Sequence Identity: 35% (104 aa)

YRLLKTLGEGTFGVAYLARNLDTKEIVVLKKVKIRGAEDGIDPQTIQELRQLCEMDHPNIVRYIGAFV--NAGTVYIATEYVPFGLLDLIKSGPNQRPLS
.  |  .||||.|. | ||   ..||| ||||..    ||.    . |.  | .. |.|||.     |      ...  .|    |  |.   |   | .
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDNMP--QPFT

AADIKCIMRQFFSGLNYLHENWLLHRDLKPANMLVSESGILKLIDFGYSCDYPSDSSDMG-DAVTIWYKPPELLYGAKQVGPALDMWTAGCIFAELLLCR
 ...|||| |   || |||.|...||||| .|.|... | .|. |||    |      |    ||.||. ||||.|...   |.||| .||| .|||. .
ETQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLVHK

PLFPGRTFGEVVQGITNLLGP---MVWPGCDHLPGYEQFKDIK-PQNQIPPLEATFRGFSTDTLDLLSKLITIDPSKRISAADALMHPYF
||.||      .. | .|||     .|||  .||  ..|   | | |    |.. |   |   . ||  |.  .| ||  | ..|   ||
PLMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNN---LKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase 91340.m00080.AA CDC2 12-213 33 2.4e-59 180.8 In-house 1-211 (301) Show / Hide 
Range on Protein: 12-213
Range on HMM: 1-211/301
Sequence Identity: 33% (70 aa)

YRLLKTLGEGTFGVAYLARNLDTKEIVVLKKVKIRGAEDG--IDPQTIQELRQLCEMD-HPNIVRYIGAFVNAGTVYIATEYVPFGLLDLIK-SGPNQRP
|  .. .||||.|| | .....|..||.|||...   ..|  .   .| |.  | |.. |||||.    ...   .|. .||. . |  . . | | . .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

LSAADIKCIMRQFFSGLNYLHENWLLHRDLKPANMLVSESGILKLIDFGYSCDYPSDSSDMG---DAVTIWYKPPELLYGAKQVGPALDMWTAGCIFAEL
.. . .| .| |  .|....| .  .|||||| | |....| .|. ||| . . .  .       . || || .||.| |.|.   . |||  ||||||.
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---LLCRPLFPG
      .|||.|
FMDVTKKPLFHG
Kinase 91340.m00080.AA CRK7 12-294 28 6.9e-57 194.66 In-house 1-343 (343) Show / Hide 
Range on Protein: 12-294
Range on HMM: 1-343/343
Sequence Identity: 28% (97 aa)

YRLLKTLGEGTFGVAYLARNLDTKEIVVLKKVKIRGA---EDGIDPQTIQELRQLCEMDHPNIVRYIGAFVNA----------GTVYIATEYVPFGLLDL
|....  ||||.|  | |.|..|.|.| ||||.  .    ..|     | | . | ...|.|||.     .            |..|   ||.   |  |
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

IKSGPNQRPLSAADIKCIMRQFFSGLNYLHENWLLHRDLKPANMLVSESGILKLIDFGYSCDYPSDS--SDMGDAV-TIWYKPPELLYGAKQV-------
 .|.  .   |   .||.|.|   |..|.|..  ||||.| .| |.  .|..|. |||    | |..   .    | | || ||||| |...        
LESKEMHH-FSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILK

-------------------------------GPALDMWTAGCIFAELLLCRPLFPGRTFGEVVQGITNLLG---PMVWPGCDHLPGYEQFKDIK--PQNQ
                               ||. |||  |||..||.  .|.|.|.   .    |  . |   | .||  . ||... .|  .      
ELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPKRQYNRRL

IPPLEATFR--GFSTDTLDLLSKLITIDPSKRISAADALMHPYF
    .  ..   .. . |||| |. . ||.||..| ..| |..|
REEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF
Kinase 91340.m00080.AA CDK-Unclassified 12-215 26 5.7e-51 165.86 In-house 1-243 (324) Show / Hide 
Range on Protein: 12-215
Range on HMM: 1-243/324
Sequence Identity: 26% (66 aa)

YRLLKTLGEGTFGVAYLARNLDTKEIVVLKKVKIRGAED----------GIDPQTIQELRQLCEMDHPNIVRYIGAFVNAGTVY-------------IAT
|| .. .||||||  ..|. ..|  .|  ||. .    .           .   .  |.  |  . | ||   .  .  .                 . .
YRMQCKYGEGTFGCVCKAIDFQTQKHVAIKKIMVNNKKGNKCKHILPLLNSKITDQREISCLQNCNHMNIIKFMDMHYDHDRCSKNPYYDNLHPSFYMVM

EYVPFGLLDLIKSGPNQRPLSAADIKCIMRQFFSGLNYLHENWLLHRDLKPANMLVSESG-----ILKLIDFGYSCDYP-------------SDSSDMGD
||.|  .    ..  |  .||  .|.  |.|...|..|||.| . |||.||.| ...  .     .||..||| .|.|              .. .   .
EYMPYTWYNQLHN--NRYNLSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQQYSTQ

AVTIWYKPPELLYGAKQVGPALDMWTAGCIFAELLLCRPLFPGRT
 .| ||. |||| | |. ... |.| .|||.||..   |.|.|||
VSTRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWFQGKPIFQGRT
Kinase 91340.m00080.AA CDK5 172-294 36 6.4e-39 120.28 In-house 160-287 (287) Show / Hide 
Range on Protein: 172-294
Range on HMM: 160-287/287
Sequence Identity: 36% (47 aa)

VTIWYKPPELLYGAKQVGPALDMWTAGCIFAELL-LCRPLFPGRTFGEVVQGITNLLG-PMV--WPGCDHLPGYE-QFKDIKPQNQIPPLEATFRGFSTD
|| || ||  | |.|.     ||| .||||||.    ||||||    .    |  ..| | .  ||.  .|| |  . ..  . .  ....   .. .  
VTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEK

TLDLLSKLITIDPSKRISAADALMHPYF
 .|||.|.. ..| .||||..||.||||
GMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase 91340.m00080.AA CDK5 12-156 37 6.6e-32 97.74 In-house 1-143 (287) Show / Hide 
Range on Protein: 12-156
Range on HMM: 1-143/287
Sequence Identity: 37% (54 aa)

YRLLKTLGEGTFGVAYLARNLDTKEIVVLKKVKIRGAEDGIDPQTIQELRQLCEMDHPNIVRYIGAFVNAGTVYIATEYVPFGLLDLIKSGPNQRPLSAA
|  .  .||||.|. | ||| .|.||| ||.|..     |.    | |   | |. |.|||| .          .  |..   |   . |      ....
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNG--EMDMH

DIKCIMRQFFSGLNYLHENWLLHRDLKPANMLVSESGILKLIDFG
 || .| |   || . ||.  ||||||| |.|..  |.||| |||
IIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFG
Kinase 91340.m00080.AA Pkinase_Tyr 12-156 31 3.4e-18 62.26 Pfam 1-156 (270) Show / Hide 
Range on Protein: 12-156
Range on HMM: 1-156/270
Sequence Identity: 31% (50 aa)

YRLLKTLGEGTFGVAYLARNL----DTKEIVVLKKVKIRGAEDGIDPQT------IQELRQLCEM-DHPNIVRYIGAFV-NAGT--VYIATEYVPFG-LL
 ...|.|||| ||. |...      .||  |  |..|     .| ...       ..|.. .... .||||||..|. .   .   .|| .||.| | ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

DLIKSG-PNQRPLSAADIKCIMRQFFSGLNYLHENWLLHRDLKPANMLVSESGILKLIDFG
|  ..  ....||.  |. .. .|  .|..||... . ||||   | ||.|... |  |||
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 91340.m00080.AA CDC2 232-294 35 1.9e-17 49.66 In-house 233-301 (301) Show / Hide 
Range on Protein: 232-294
Range on HMM: 233-301/301
Sequence Identity: 35% (25 aa)

WPGCDHLPGYEQ----FKDIKPQNQIPP-LEATFRGFSTD--TLDLLSKLITIDPSKRISAADALMHPYF
|||.. || | .    .| .......|  ..     . .|   .|||.... .||.||||| .|| ||||
WPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQ-SCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase 91340.m00080.AA TyrKc 12-294 21 1.1e-11 -33.76 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-294
Range on HMM: 1-280/280
Sequence Identity: 21% (69 aa)

YRLLKTLGEGTFGVAYLARNLDTKEIVVLKKVKIRGAEDGIDPQTIQELRQ----LCEM--DHPNIVRYIGAFVNA-------GTVYIATEYVPFG-LLD
 .|.|.|||| ||. |...     . |  |..|            ......    .|.   .|||||| .|. .         . ..| .||.| | |.|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

LIKSGPNQRPLSAADIKCIMRQFFSGLNYLHENWLLHRDLKPANMLVSESGILKLIDFGYSCDYPSD-------SSDM------GDA-VTIWYKPPELLY
 ...  ..  |. .|   .. |  .| .|||.. . ||||   | ||.| .. |  ||| | |  .|       .  .      |.. . |   .|| . 
YLRKHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

GAKQVG---PALDMWTAGCIFAELL-LCRPLFPG-----RTFGEVVQGITNLLGPMVWPG----CDHLPGYEQFKDIKPQNQIPPLEATFRGFSTDTLDL
   . |   .. | |  |    |.. .. .  ||      .  ||.. . .   ..  |                              | . ...  ..
---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------------FVCCPDEMYQI

LSKLITIDPSKRISAADALMHPYF
 ..    ||..| . ..   | .|
MKQCWHEDPEDRPTFSEI--HECF
Kinase 91340.m00080.AA CDK-Unclassified 268-294 22 0.000618 8.68 In-house 298-324 (324) Show / Hide 
Range on Protein: 268-294
Range on HMM: 298-324/324
Sequence Identity: 22% (6 aa)

LDLLSKLITIDPSKRISAADALMHPYF
..... .   .| .| ..  .| ||.|
NNCEFQMVMYQPYNRWKCMEILQHPWF