84270.m00585

Species: T.vaginalis
Alias: 84270.m00585, TvagK0034
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
84270.m00585.AA Protein None 451 None Fasta, JSON
84270.m00585.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 84270.m00585.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84270.m00585.AA CAMKL 6-257 37 9.60000000001e-122 390.34 In-house 1-297 (297) Show / Hide
Range on Protein: 6-257
Range on HMM: 1-297/297
Sequence Identity: 37% (112 aa)

YRLFRTIGDGSFATVKLGFD-VFTKEQVAVKIINKCMIK-TEVDMNL-----------LMQEVEVMRKLD---HPGIVKFYDFLEDDAA------YYLII
||. .|.| |||..|||. .  .|.|.||.|||.|  |.  .. ..            . .|.. |..|.   || |.|.|. .|..        .||. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCGGGE--LFDFIISR----QRVEEILAKRLFKQILLAVNYIHSQNIVHRDLKPENLLLTENN--TVKLIDFGLCS------INADKPMTNRCGSACYI
|||.|||  |||.|...    .| .|  |.|.|.||. ||||.||..|||||.||||.||.||.  ..|.||||..       .. .. .. .||| .| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEALTQ--QSYMGQPADVWALGVILYALVDGSLPWNYEDPD-------KMYKQITTGSFAPP--KELSPECLDLIQRIFNPNPDERLTIQQILAHPWF
||| .    ..| |...|.|..||||||.| | ||.. ..         ..|..| .| . ||  ...| .| |||... ..||..| ||.||. |||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase 84270.m00585.AA CAMK 11-257 26 2.1e-119 386.6 In-house 1-425 (425) Show / Hide
Range on Protein: 11-257
Range on HMM: 1-425/425
Sequence Identity: 26% (113 aa)

TIGDGSFATVKLGFDVFTK------------EQVAVKIINKCMIK-------------------------TEVDMNLLMQEVEVMRK-------LDHPGI
|.| |||..|||...  |.            ..||.|||.|  .|                         ...|.  ...|.|.|.|       |||| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKFYDFLED-------------------DAAYYLII---EYCGGGEL----FDFIISR---------------QRVEEILAKRLFKQILLAVNYIHSQNI
.|.|.. ||                   |  .|..    ||| ||||    ||.|...                |..|  |.|.|.||. ||.|.||.||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPENLLLTEN-----------------NTVKLIDFGLCS-INA------------------------DKPMTNRCGSACYIA-PEALTQ------
|||||||||.||..|                 |..|.||||.   ..                         ...|. .||. .|.| || | .      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------QSYMGQPADVWALGVILYALVDGSLPWNYE-------------DPDKMYKQITTGSFA-PPKELSP-----------------------ECLD
       . | |...|.|..|||||... | .|.. .             .. .....|..| .  ||...||                       || |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIQRIFNPNPDERLTIQQILAHPWF
||... ...|..|.||.|.|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 84270.m00585.AA MARK 6-257 42 5.5e-112 367.28 In-house 1-262 (262) Show / Hide
Range on Protein: 6-257
Range on HMM: 1-262/262
Sequence Identity: 42% (112 aa)

YRLFRTIGDGSFATVKLGFDVFTKEQVAVKIINKCMIKTEVDMNLLMQEVEVMRKLDHPGIVKFYDFLE--DDAA-YYLIIEYCGGGELFDFIISR--QR
|.. .||| ||.|.|||. .. |...||.||..|  .     |. .| |.|.|.||||| |.|...  |  .     ||| ||..||||.|.|...   |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

VEEILAKRLFKQILLAVNYIHSQNIVHRDLKPENLLLTENN--TVKLIDFGLCSIN-ADKPMTNRCGSACYIAPEALTQQSYMGQPADVWALGVILYALV
 .| .|.|.|.||. |||| ||.||||||.||||.|. ||.   .|.||||.. .   ..  .  ||.  | ||| . .. | |...|.|.|||.||..|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

DGSLPWN--YEDPDKMYKQITTGSFAPPKELSPECLDLIQRIFNPNPDERLTIQQILAHPWF
 |..|.     |  ..||.|..|..  |  .|.|| .||||....||.|| ||..|. |||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 84270.m00585.AA AMPK 6-257 42 8.20000000001e-108 321.14 In-house 1-254 (254) Show / Hide
Range on Protein: 6-257
Range on HMM: 1-254/254
Sequence Identity: 42% (108 aa)

YRLFRTIGDGSFATVKLGFDVFTKEQVAVKIINKCMIKTEVDMNLLMQEVEVMRKLDHPGIVKFYDFL-EDDAAYYLIIEYCGGGELFDFIISRQRVEEI
| .  ||| |.|  ||.|    |.|.||.||.|| .|| . ... .  |.. .... || |.. |. . |     ....||  ||||||.|....|..| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

LAKRLFKQILLAVNYIHSQNIVHRDLKPENLLLTENNTVKLIDFGLCSINAD-KPMTNRCGSACYIAPEALTQQSYMGQPADVWALGVILYALVDGSLPW
 |.|.|.||. .| |.|  .||||||||||||| .|. .|. ||||  .  | .     ||| || |||  . . | |   |.|  ||||||.. | || 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

NYEDPDKMYKQITTGSFAPPKELSPECLDLIQRIFNPNPDERLTIQQILAHPWF
  |.  . || |. | .  || ||||. |||... ...| .|.||..| .||||
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase 84270.m00585.AA S_TKc 6-257 34 3.2e-104 353.47 SMART 1-231 (231) Show / Hide
Range on Protein: 6-257
Range on HMM: 1-231/231
Sequence Identity: 34% (93 aa)

YRLFRTIGDGSFATVKLGFDVFTKEQVAVKIINKCMIKTEVDMNLLMQEVEVMRKLDHPGIVKFYDFLEDDAAYYLIIEYCGG--GELFDFIISRQR---
|.. |.|| |.|..|... .. |...||.|||.          . ...|.....| .|| |||.||. .|   .|.. |||.|  |.|||.| .|.|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---VEEILAKRLFKQILLAVNYIHSQNIVHRDLKPENLLLTENNTVKLIDFGLCSINADKPMTNRCGSACYIAPEALTQQSYMGQPADVWALGVILYALV
     |  |.....||..|..|.||..|.||||||||.||.|  ..|..||||. .      |  ||.  |.||| |   .| . ..|.|..|.||| ..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

DGSLPWNYEDPDKMYKQITTGSFAPPKELSPECLDLIQRIFNPNPDERLTIQQILA-------HPWF
 |  |.   ....|.|.|           |||..|.|..... .|..|.|. ..|.       ||||
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 84270.m00585.AA Pkinase 6-257 33 7.8e-99 339.45 Pfam 1-293 (293) Show / Hide
Range on Protein: 6-257
Range on HMM: 1-293/293
Sequence Identity: 33% (98 aa)

YRLFRTIGDGSFATVKLGFDVFTKEQVAVKIINKCMIKTEVDMNLLM-QEVEVMRKLDHPGIVKFYDFLEDDAAYYLIIEYCGGG----ELFDFII--SR
|.. |.|| |||..|... .. | ..||||||.|. .| ..|....  .|...|..|.|| ||..||. ||.  .|.. |||.||    .|||.|   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

QRV--EEILAKRLFKQILLAVNYIHSQNIVHRDLKPENLLLTENNTV----KLIDFGLCS---INADKPMTNRCGSACYIAPEALTQQSYMGQPADVWAL
 ..  .|  .|. ..||| ...|.||..|.||||||||.|. .|...    |..||||.    .  .  || .||.  |.||| .  ..| |...|.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYALVDGSLPWNYE------DPDKMYKQITTGSFAPPKELS---------------------PECLDLIQRIFNPNPDERLTIQQILAHPWF
|.||| .. | .|.  .      |...|...|  . .  . . .                     .||.|.| ......| .|.|..||| ||||
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 84270.m00585.AA RAD53 6-257 31 8.1e-89 264.63 In-house 1-305 (305) Show / Hide
Range on Protein: 6-257
Range on HMM: 1-305/305
Sequence Identity: 31% (96 aa)

YRLFRTIGDGSFATVKLGFDVFTKEQVAVKIINKCMIK---TEV--DMNLLMQEVEVMRKLDHPGIVKFYDFLED-DAAYYLIIEYCGGGELFDFIISRQ
| . ...| | |.||||...  | ..||.|||.| ..    . .  .|  .| |||...|| || |...||. .. .  ||...|. .|||||..|.|. 
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

R----VEEILAKRLFKQILLAVNYIHSQNIVHRDLKPENLLLTENN------------------TVKLIDFGLCSINADK-PMTNRCGSACYIAPEALTQ
|    . |  .|..|.|...||.|.|...|.|||||||| |. ...                   .|. |||| ..  ..  |.  ||.  | ||| .| 
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

Q---------------SYMGQPADVWALGVILYALVDGSLPWN--YED---PDKMYKQITT-GSFAPPKE----LSPECLDLIQRIFNPNPDERLTIQQI
.                | .   |.| .|.||| .  | .|    | .   ......||.. |... |..     | | .|||..  . .|..|.|| ..
KGHNCYHENEERQVQVGY-TKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEA

LAHPWF
| |||.
LNHPWM

Kinase 84270.m00585.AA QIK 6-257 37 5.8e-86 291.9 In-house 1-272 (272) Show / Hide
Range on Protein: 6-257
Range on HMM: 1-272/272
Sequence Identity: 37% (102 aa)

YRLFRTIGDGSFATVKLGFDVFTKEQVAVKIINKCMIKTEVDMNLLMQEVEVMRKLDHPGIVKFYDFLEDDAAYYLIIEYCGGGELFDFIISRQR-----
| . |||| | ||.|||.    ||..||.||| |  . .| ... .  ||..|  |.|| |.| |. .| | . |.. ||| .||.|| ...  |     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQL-DEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------VEEILAKRLFKQILLAVNYIHSQNIVHRDLKPENLLLTENNTVKLIDFGLCS-INADKPMTNRCGSACYIAPEALTQQSYMGQPA
               ..|  |.| |.||..|| | |..|||||||| ||.|| .|  .|..|||.      ....   |||  | ||| .  ..| |  .
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DVWALGVILYALVDGSLPWNYEDPDKMYKQITTGSFAPPKELSPECLDLIQRIFNPNPDERLTIQQILAHPWF
|.| .||.||.|| |.||   .   .. . .  | |  |  .| .| .|| .    .|. |.||.||. |.| 
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase 84270.m00585.AA Ciliate-E2 6-257 25 8.3e-84 284.73 In-house 1-365 (365) Show / Hide
Range on Protein: 6-257
Range on HMM: 1-365/365
Sequence Identity: 25% (98 aa)

YRLFRTIGDGSFATVKLG--FDV---------------------FTKEQVAVKIINKCMIKTEVDMNLLMQEVE----------VMRKLDHPGIVKFYDF
| . . || |.|..|...    |                     ... ..|.||..| .|.    .. .|.|..          ....|.|| |.|.|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LE--DDAAYYLIIEYCGGGELFDFIISR-----------QRVEEILAKRLFKQILL---------------AVNYIHSQN-IVHRDLKPENLLLTENNTV
 .  ||  .||. ||| ||.|||.|...           ..  |  .|...||||                |..|.||.| |.|||.||||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLIDFGLCSINADK-------PMTN--------------------------RCGSACYIAPEALTQQSYMG--------QPADVWALGVILYALVDGSLP
|.|||||. .. |.       .. .                           ||.. | ||| |  ..| .          .|.|.|||||| .. | .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WNYEDPDKMYKQITTGSFAPP------------------KELSPECLDLIQR----IFNPNPDERLT-IQQILAHPWF
.        ..||  . .  |                  |..|.|| |||..    ... .|..|.| ..||| ||||
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 84270.m00585.AA MELK 6-257 39 6.2e-82 278.52 In-house 1-254 (254) Show / Hide
Range on Protein: 6-257
Range on HMM: 1-254/254
Sequence Identity: 39% (101 aa)

YRLFRTIGDGSFATVKLGFDVFTKEQVAVKIINKCMIKTEVDMNLLMQEVEVMRKLDHPGIVKFYDFLEDDAAYYLIIEYCGGGELFDFIISRQRVEEIL
| .. .|| | || |||   ..| ..||.||..|  .    |.  .  |.. ...| |  | ..| ..| .  .....||| |||.||.||...|.||  
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQL--GHDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEE

AKRLFKQILLAVNYIHSQNIVHRDLKPENLLLTENNTVKLIDFGLCSI---NADKP-MTNRCGSACYIAPEALTQQSYMGQPADVWALGVILYALVDGSL
.. .|.||. |. |.|||   ||||||||||..|.  .||||||||.    . |.  .   |||  | ||| .  ..|.|  ||||..|..||.|. | |
TRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PWNYEDPDKMYKQITTGSFAPPKELSPECLDLIQRIFNPNPDERLTIQQILAHPWF
|.. .    |||.|  | .  || ||||  .|....   .|. |. ....| ||| 
PFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV

Kinase 84270.m00585.AA Ciliate-E2-Unclassified 6-257 26 9.6e-81 274.56 In-house 1-352 (352) Show / Hide
Range on Protein: 6-257
Range on HMM: 1-352/352
Sequence Identity: 26% (93 aa)

YRLFRTIGDGSFATVKLGFDVFTKEQV-------AVKIINKCMIKTEVDMNLLMQEVE----------------VMRKLDHPGIVKFYDFLEDDAAYYLI
|.. ..|| |.|..|..  .  .| |.        ..|.... |... .... |.|..                 .. ..|| |||...  .|.   |..
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

IEYCGGGELFDFIISR-----------------QRVEEILAK-----RLFKQILLAVNYIHSQN-IVHRDLKPENLLLTENN---TVKLIDFGLCS----
 ||| ||.|...| .|                 ....|  ||     ..|.|||.. .|.|..| |.|||.||||.|...|.    .|.||||...    
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

-------------INADKPMTNRCGSACYI----APEALTQQSYMG---QPADVWALGVILYALVDGSLPWNYEDPDK----------------MYKQIT
             |. .. |. .||. .|.    ||| | .| | .     .|.|.||||||... | .| .... ..                .|..| 
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

TGSFAPPK--------ELSPECLDLIQ----RIFNPNPDERLTIQQILAHPWF
 . .  ||         .|||. |.|.    .... ||..|.|..||| ||||
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 84270.m00585.AA ULK 6-257 29 6.2e-76 258.59 In-house 1-324 (324) Show / Hide
Range on Protein: 6-257
Range on HMM: 1-324/324
Sequence Identity: 29% (95 aa)

YRLFRTIGDGSFA-TVKLGFDVFT---KEQVAVKIINKC-MIKTEVD------MNLLMQEVEVMRKLD---HPG--IVKFYDFLEDDAA--YYLIIEYCG
| | . .| |||. .|  |... |   ...||.|.|.|. |.| . .      ..||..|...|.||.   ||   |||.||..|..    .|.| ||| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGELFDFIISRQRVEEIL----------AKRLFKQILLAVNYIHSQNIVHRDLKPENLLLTENN------------TVKLIDFGLCSI-NADKPMTNRC-
|| |...|  ...  |            |.  ||||. .  ..|..||.|||.||.|.|.....            ..|. |||.. . . .    . | 
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

---------GSACYIAPEALT----QQSYMGQPADVWALGVILYALVDGSLP---WNYEDPD----KMYKQ-------ITTGSFAPPK-----ELSPECL
         |.  | ||. |     |. |    .|.| ||.|.| .. |. |   | ..| .    |. ..       | .  . .||      .|||| 
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

DLIQRIFNPNPDERLTIQQILAHPWF
|||.| .  ....| ....|..||||
DLIRRMLQYDEKDRISWEEIFNHPWF

Kinase 84270.m00585.AA TyrKc 6-257 22 2.9e-21 77.9 SMART 1-280 (280) Show / Hide
Range on Protein: 6-257
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

YRLFRTIGDGSFATVKLGFDVFTKEQVAVKIINKCMIKTEVDMNLLMQEVEVMRKL--DHPGIVKFYDFLEDD-------AAYYLIIEYCGGGELFDFII
 .| ...| | | .| .|      .||||| ....       .  .|.| ..|.||  .|| ||..|    ..         .... ||. .| | |.. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SRQR-VEEILAKRLFKQILLAVNYIHSQNIVHRDLKPENLLLTENNTVKLIDFGLCSINADK-------PMTNRCG--SAC------YIAPEALTQQSYM
.... .          ||    .|.||.|..||||   | |..||.|||  ||||.    |.        .    .  ..         |||..    . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-

GQPADVWALGVILY-ALVDGSLPWNY-----EDPDKMYKQITTGSFAPPKEL---------SPECLDLIQRIFNPNPDERLTIQQILAHPWF
    |||. || ..  . .|  |.        ... ..... .|   |. .          ..|  .....  . .|..| | ..|  |  |
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 84270.m00585.AA Pkinase_Tyr 6-151 30 6.1e-20 68.16 Pfam 1-158 (270) Show / Hide
Range on Protein: 6-151
Range on HMM: 1-158/270
Sequence Identity: 30% (49 aa)

YRLFRTIGDGSFATVKLGFDV----FTKEQVAVKIINKCMIKTEVD--MNLLMQEVEVMRKL-DHPGIVKFYDFLE-DDAA--YYLIIEYCGGGELFDFI
 .. ...| |.| .|..|        || .||||.. |    .. .  .  .|.|...|..| .|| ||..|     ..    .|.. ||. .| | |. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

IS----RQRVEEILAKRLFKQILLAVNYIHSQNIVHRDLKPENLLLTENNTVKLIDFGLC
 .    .|..          ||  . .| .|.|..||||   | |.||||.||  ||||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA

Kinase 84270.m00585.AA APH 125-153 18 0.000986 13.61 Pfam 172-204 (248) Show / Hide
Range on Protein: 125-153
Range on HMM: 172-204/248
Sequence Identity: 18% (6 aa)

IVHRDLKPENLLLT--ENNTVK--LIDFGLCSI
..|.|..| |....  ....    .||.. . .
WCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACW