Gene 83711.m00150 (T.vaginalis)

83711.m00150

Species: T.vaginalis
Alias: TvagK0456, 83711.m00150
External Links:
Annotation:

Classification

Group: CK1
Family: TTBK

Sequence

Name Sequence Type Origin Length Description Download
83711.m00150.AA Protein None 350 None Fasta, JSON
83711.m00150.kin_dom Protein Kinase Domain None 145 None Fasta, JSON

Protein domain

Protein domains of 83711.m00150.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 83711.m00150.AA CK1 23-277 27 1.5e-83 283.85 In-house 1-339 (339) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-339/339
Sequence Identity: 27% (95 aa)

YRIDKHIGHGGYG-EIYAV-----TDISTN-----KHYAMKYETKSGE--NKGLVMEKEISKQLSGS-------------------KNFAIQYGEGTYKG
... |.|| ||.| .|| |     .|...|     ..|||| | |. .  .  | .| .. |.| |                    . . ..|. .. ..
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

--NKYMVMELLGTSLSNTRR--QLEGRHYSPYSALYLSYYTICCIEDFHSRGYIHRDIKPGNFLLRPDWD--------------FPVCLVDFGLAI-SYI
  ..||||.||| .|.  |.  .. .|. |  ..| . . ..  .|. |..|.|||||||.||..    .                | ..|||.|   |.
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR

DR-----------QTKEHIPNRN---SVGFTG-TCKYASMNAHEGHELSRRDDLISWFYSVVEFYAGR--LPWPASRDKDA-----TYDKKQRTPPETLL
|.            |..|.| |.    .||.| |..|.|.|.|.|.|..||||| |||| ..|.  |   |||   .|..        ..|.    |...
DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM

RK------------LPSFFGEIYQHIFSLDFFAKPDYQRI
              .|. | .|...| ||... .|||. |
STPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase 83711.m00150.AA TTBKL 23-281 29 3.5e-67 225.88 In-house 1-288 (288) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-288/288
Sequence Identity: 29% (85 aa)

YRIDKHIGHGGYGEIYAVTDIST-NKHYAMKYETKSGENKG--LVMEKEISKQLS--GSKNFAIQYGEGTYKGNKYMVMELLGTSLSNTRRQLEGRH-YS
..| | || ||.|..| | |... ....||| | .. |...  . || .. ..|.  ||. |.. .. | .|.  .|||.|.| .|.  |...  ..  |
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

PYSALYLSYYTICCIEDFHSRGYIHRDIKPGNFLLRPDWD-----FPVCLVDFGLAISYIDRQT----------KEHIPNRN---SVGFTGTCKYASMNA
. ... ... .. .. . |. |.||||.||.|. .    .       | |.|||.|  |.. .           ... . ||   ...| || .|.|.|.
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM

HEGHELSRRDDLISWFYSVVEFYAGRLPWPASRDKDATYDKKQRTPPETLLRK------LPSFFGEIYQHIFSLDFFAKPDYQRIKELM
|.. |..| ||| ||.|...|...| |||  . ||. .. .|. .  |.|  .      .|| |.....|. ||..   |||. | |..
HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase 83711.m00150.AA TTBK 23-277 37 4.2e-55 189.38 In-house 1-257 (257) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-257/257
Sequence Identity: 37% (98 aa)

YRIDKHIGHGGYGEIYAVTDISTN-KHYAMKYETKSGENKGLVMEKEISKQLSGSKNFAIQYGEGTYKGNKYMVMELLGTSLSNTRRQLEGRHYSPYSAL
 .. | || ||.||||  .|. ..  . |.| |        | ||  . |.| | .     .| |      ||||.|.| .|.. ||.     .|  ..|
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTL

YLSYYTICCIEDFHSRGYIHRDIKPGNFL--LRPDWDFPVCLVDFGLAISYIDRQTKEHIPNRNSVGFTGTCKYASMNAHEGHELSRRDDLISWFYSVVE
 |    .  ||  || |. |||||| ||   . |     . ..|||||  |.  .  |  | |.. || ||  ||| |||   |. |.||| | ||  ||
RLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACG-EVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVE

FYAGRLPWPASRDKDATYDKKQRTPPETLLRKLPSFFGEIYQHIFSLDFFAKPDYQRI
|  | |||   .|||     |..     ||  .|. |    .|| ||... .|||| |
FVQGQLPWRKIKDKDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase 83711.m00150.AA CK1-D 23-277 38 6.1e-47 162.27 In-house 1-261 (261) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-261/261
Sequence Identity: 38% (101 aa)

YRIDKHIGHGGYGEIYAVTDISTNKHYAMKYETKSGENKGLVMEKEISKQLSGSKNFAIQYGEGTYKGNKYMVMELLGTSLSNTRRQLEGRHYSPYSALY
||| . || | .|.||  |.|.||   |.| |.   .   | .|  . | ..|          |       |||.||| ||       . |..|    | 
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCH-RKFSLKTVLM

LSYYTICCIEDFHSRGYIHRDIKPGNFLLR-PDWDFPVCLVDFGLAISYIDRQTKEHIPNRNSVGFTGTCKYASMNAHEGHELSRRDDLISWFYSVVEFY
|.   || ||  |.| .||||||| |||.        | ..|||||  | | .|..||| |     ||| .|||.| | | | |||||| |  | .. | 
LADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFN

AGRLPW-----PASRDK-DATYDKKQRTPPETLLRKLPSFFGEIYQHIFSLDFFAKPDYQRI
 | |||      . |.| .   .||  |. .|| . .|| | .   .  .| |  ||||  .
RGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase 83711.m00150.AA CK1-A 23-277 35 3.1e-44 153.28 In-house 1-261 (261) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-261/261
Sequence Identity: 35% (94 aa)

YRIDKHIGHGGYGEIYAVTDISTNKHYAMKYETKSGENKGLVMEKEISKQLSGSKNFAIQYGEGTYKGNKYMVMELLGTSLSNTRRQLEGRHYSPYSALY
||. ..|| | .|.||    |   .  |.| | .      |. |  . ..|.|   .      |. | .  |||.||| || .    .  |...    | 
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDL-FNFCKRRFTMKTVLM

LSYYTICCIEDFHSRGYIHRDIKPGNFLLRPDWDF-PVCLVDFGLAISYIDRQTKEHIPNRNSVGFTGTCKYASMNAHEGHELSRRDDLISWFYSVVEFY
|    |  ||  | ...||||||| |||.  .     . |.|||||  | | .|..||| |.    ||| .|||.||| | | |||||. |  | .. | 
LADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFN

AGRLPWP--ASRDKDATYD----KKQRTPPETLLRKLPSFFGEIYQHIFSLDFFAKPDYQRI
 |.|||       |   |.    ||  || | | .  |. |  . ... .| |  .|||  .
RGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase 83711.m00150.AA CK1-G 23-277 33 7.9e-39 129.18 In-house 1-266 (266) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-266/266
Sequence Identity: 33% (90 aa)

YRIDKHIGHGGYGEIYAVTDISTNKHYAMKYETKSGENKGLVMEKEISKQLSGSK-NFAIQYGEGTYKGNKYMVMELLGTSLSNTRRQLEGRHYSPYSAL
||. | || | .||..  . . .| | | | |    .   |  |    |.|.|   .    |  |       |||.||| ||      . .|..|  . .
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDL-FDWCDRKFSVKTVC

YLSYYTICCIEDFHSRGYIHRDIKPGNFLL-RPDWDFP--VCLVDFGLAISYIDRQTKEHIPNRNSVGFTGTCKYASMNAHEGHELSRRDDLISWFYSVV
 ..   |  .|. ||.  | ||.|| |||  ||    .  . ..|||.|  ||| .|| ||| |     |||  | | | | | | |||||. .      
MVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFM

EFYAGRLPW-----PASRDK-DATYDKKQRTPPETLLRK--LPSFFGEIYQHIFSLDFFAKPDYQRI
 |  | |||     .  . . .   |.|..|..| |.    .|  |.   . . .|||| .|||  .
YFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase 83711.m00150.AA CK1-Unclassified 131-227 50 2.8e-35 101.58 In-house 117-216 (244) Show / Hide 
Range on Protein: 131-227
Range on HMM: 117-216/244
Sequence Identity: 50% (50 aa)

IEDFHSRGYIHRDIKPGNFLL--RPDWDFPVCLVDFGLAISYIDR-QTKEHIPNRNSVGFTGTCKYASMNAHEGHELSRRDDLISWFYSVVEFYAGRLPW
|| .|....||||||| |||   .      | ..||||.  |||.  |..||| |.  ..|||. ||| ||| |.| |||||| |  |  . |  |.|||
IEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLESLGYVLIYFLKGSLPW
Kinase 83711.m00150.AA CK1 128-210 48 9.8e-31 103.13 In-house 115-199 (271) Show / Hide 
Range on Protein: 128-210
Range on HMM: 115-199/271
Sequence Identity: 48% (41 aa)

ICCIEDFHSRGYIHRDIKPGNFLLRP-DWDFPVC-LVDFGLAISYIDRQTKEHIPNRNSVGFTGTCKYASMNAHEGHELSRRDDL
|. || .|....||||||| |||      .  .. ..|||||  |.|  |..||| |.  ..|||. ||| |.| |.| |||||.
IQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDM
Kinase 83711.m00150.AA Worm6 159-277 31 1.2e-27 96.33 In-house 151-279 (279) Show / Hide 
Range on Protein: 159-277
Range on HMM: 151-279/279
Sequence Identity: 31% (41 aa)

VCLVDFGLAI--SYIDRQTKEHIPNR-NSVGFTGTCKYASMNAHEGHELSRRDDLISWFYSVVEFYAGRLPWPASRDKDATY-DKKQ--RTPP----ETL
....|||..    |...... . | | . .|| || .||. ..| | |..|.||. |||| .||.  |.|||  ..|.|.    ||.  |.      . .
IYMLDFGMCRRKKYCNKGNELRTP-RWTACGFRGTVRYAPLACHKGQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMF

LRKLPS-FFGEIYQHIFSLDFFAKPDYQRI
... |   | .| . | ..... .|||. |
FGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase 83711.m00150.AA Worm6 23-149 34 7.8e-26 89.81 In-house 1-135 (279) Show / Hide 
Range on Protein: 23-149
Range on HMM: 1-135/279
Sequence Identity: 34% (46 aa)

YRIDKHIGHGGYGEIYAVTDISTNK--HYAMKYET--KSGENKGLVMEKEISKQLSGSK--NFAIQYGEGTYKG--NKYMVMELLGTSLSNTRRQLEGRH
. ..| || ||.| .| |.| |..|  ..||| |   .. . . | ||  . | .  .|  .|      |...    .|.||.|.| .|.. |. ...|.
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

YSPYSALYLSYYTICCIEDFHSRGYIHRDIKPGNF
.|   .| ..  ..  ||| |. |.||||.|||||
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNF
Kinase 83711.m00150.AA Ciliate-E2-Unclassified 23-190 20 9.7e-20 65.17 In-house 1-225 (352) Show / Hide 
Range on Protein: 23-190
Range on HMM: 1-225/352
Sequence Identity: 20% (47 aa)

YRIDKHIGHGGYGEIYAVTDISTNKHYAMKYETKSGENKGLVM---EKEISKQLSGSKN-----------------------FAIQYGEG-TYKGNKYMV
|.| | ||.||.|..| . ...... |||||  |. ..| . .   . ||. ..   .|                       | . . .  . | | |.|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MELL-GTSLSNTRRQLEG---------------RHYSPYSAL-----YLSYYTICCIEDFHSRG-YIHRDIKPGNFLLRPDW-DFPVCLVDFGLAISYID
||.. | .|..  .. ..               .. . . |.     .. .. ....|  |. .  ||||||| | |.  .   . ... |||... |..
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

RQTKEHI---------PNRNSVGFTGT
 . ..           .. ..  |.||
NNNCD-TNQQQKMQIWKQQMMWTFCGT
Kinase 83711.m00150.AA S_TKc 23-269 21 1.4e-15 51.67 SMART 1-231 (231) Show / Hide 
Range on Protein: 23-269
Range on HMM: 1-231/231
Sequence Identity: 21% (61 aa)

YRIDKHIGHGGYGEIYAVTDISTNKHYAMKYETKSGENKGLVMEKEISKQLSGSKNFAIQYGEGTYKGNKYMVMELLGT---SLSNTRRQLEGRH----Y
|.| ..||.|..|. | .....|....|.|        . .  | .| |.  . .|    |.     .. |||||....   .|    ..  ..     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

SPYSALYLSYYTICCIEDFHSRGYIHRDIKPGNFLLRPDWDFPVCLVDFGLAISYIDRQTKEHIPNRNSVGFTGTCKYASMNAHEGHELSRRDDLISWFY
..  | .. | ..| .|  ||.| ||||.|| | ||       . . |||||  .                | ||  | .                   |
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL--------------TTFCGTPWYMAPEVL--------------GY

SV------------VEFYAGRLPWPASRDKDATYDKKQRTPPETL------LRKLPS---FFGEIYQ---HIFSLDFF
.              |...|. |.|   . .....|    .|| .      |.| |.      |. |   .| .  .|
GKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 83711.m00150.AA CK1-Unclassified 23-103 32 4.7e-15 40.88 In-house 1-90 (244) Show / Hide 
Range on Protein: 23-103
Range on HMM: 1-90/244
Sequence Identity: 32% (29 aa)

YRIDKHIGHGGYGEIYAVTDISTNKHYAMKYETKSGENKGLVMEKEISKQLSGSK-------NFAIQYGEGTY--KGNKYMVMELLGTSL
||. . || |  |||| .... ||...|.| | |  ... |. |  | ..| . .       ...  |  |.    .  .|||.||| ||
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSL
Kinase 83711.m00150.AA CK1 23-103 31 8.1e-14 44.13 In-house 1-91 (271) Show / Hide 
Range on Protein: 23-103
Range on HMM: 1-91/271
Sequence Identity: 31% (29 aa)

YRIDKHIGHGGYGEIYAVTDISTNKH---YAMKYETKSGENKGLVMEKEISKQLSG------SKNFAIQYGEGTY--KGNKYMVMELLGTSL
||. . || |  |.|| .... ||..   .|.| | .  ..  |. |  | |.| |      .....  |  |.   .   .|||.||| ||
YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSL
Kinase 83711.m00150.AA Pkinase 23-190 26 1e-13 49.62 Pfam 1-174 (293) Show / Hide 
Range on Protein: 23-190
Range on HMM: 1-174/293
Sequence Identity: 26% (49 aa)

YRIDKHIGHGGYGEIYAVTDISTNKHYAMKYETKSGENKGLVM------EKEISKQLSGSKNFAIQYGEGTY-KGNKYMVMELLGT-----SLSNTRRQL
|.| . || |..|. |  ....|.| .|.|   |..|...  .      | .| | | ...|  ... .  . |.. |||||...      .|.   . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNI-VRLYDWFEDKDHIYMVMEYCEGGLYVMDLF---DYI

E---GRHY--SPYSALYLSYYTICCIEDFHSRGYIHRDIKPGNFLLRPDWDF--PVCLVDFGLAISYIDRQTKEHIPNRNSVGFTGT
.   .. .  |.  .    | ... .|  ||.| ||||.|| |.|.  . .   .|.. |||||  .       . .|.   .|.||
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGT
Kinase 83711.m00150.AA CK1 238-275 35 1.9e-07 21.94 In-house 233-271 (271) Show / Hide 
Range on Protein: 238-275
Range on HMM: 233-271/271
Sequence Identity: 35% (14 aa)

DKKQRTPPETLLRK-LPSFFGEIYQHIFSLDFFAKPDYQ
.||. ||.|.| .  .|. | .  ... .|.|. ||||.
EKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM