Gene 94652.m00102 (T.vaginalis)

94652.m00102

Species: T.vaginalis
Alias: TvagK0115, 94652.m00102
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
94652.m00102.AA Protein None 331 None Fasta, JSON
94652.m00102.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 94652.m00102.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94652.m00102.AA CAMK 25-273 25 2.7e-108 350.18 In-house 1-425 (425) Show / Hide 
Range on Protein: 25-273
Range on HMM: 1-425/425
Sequence Identity: 25% (109 aa)

IIGRGSFAVVVLVTRIADG------------EKFACKVISQEYLIE-------------------------NKLVESFKREVENFGK-------LDHPNI
..|||||..| |.... ..            .|.|.|.|. . | .                          |  ....||.|   |       ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LRLIDFLSD-------------------EKLIYMIM---TLCDAG----DLHGYIADHGP---------------FSEYQAKAIFKQIISAVDYLHSLNI
..|...  |                   .| .||.|    .|. |    ||  || .||.               |.| .|. .|.||.|||.|.||.||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDLKPENILLEKDM-----------------TVKLADFGFSRETVG------------------------NQLMKTKCGSPIYTA-PEIITQ------
.||||||||||| ...                 ..|..||||...  .                        .|.||| ||.| | | ||.. .      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------PEYDGKMADMWSVGVILFVMLTGKIPWESST------------NETQLFFQIRTARFH-IPENINPI-----------------------AAK
        .|.|. .||||.||||..||.|. |.....            |. .|| .|...... .|. . ||                       .  
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIGELMVPQPEMRCTAKEVLTHPWI
||  .... || | |....| |||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 94652.m00102.AA CAMKL 20-273 33 5.4e-101 323.05 In-house 1-297 (297) Show / Hide 
Range on Protein: 20-273
Range on HMM: 1-297/297
Sequence Identity: 33% (100 aa)

YRFESIIGRGSFAVVVLVTR-IADGEKFACKVISQEYLIENKLVESF------------KREVENFGKLD---HPNILRLIDFLSDEKL------IYMIM
||..  .|.|||..| | |  .  ||| | |.|  . . ..  ...             .||..   .|.   |||| .| . . ...       ||..|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

TLCDAGD--LHGYIADH----GPFSEYQAKAIFKQIISAVDYLHSLNIAHRDLKPENILLEKDM--TVKLADFGFSRETV-G----NQLMKTKCGSPIYT
 .|. |.  |. ||  |    |...| .|. .|.||.|||.|.||..|.|||.||||||| ...  ..|..||||| .   .    .|..|| |||| | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIITQ--PEYDGKMADMWSVGVILFVMLTGKIPWESST-------NETQLFFQIRTARFHIPENINP-IAAKLIGELMVPQPEMRCTAKEVLTHPWI
||||.     .|||. .|.|| ||||..|..|. |..  |       |   |. .|..  ...|  . .  .  ||  .... || | |..... ||| 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 94652.m00102.AA MARK 20-273 38 5.2e-96 314.31 In-house 1-262 (262) Show / Hide 
Range on Protein: 20-273
Range on HMM: 1-262/262
Sequence Identity: 38% (102 aa)

YRFESIIGRGSFAVVVLVTRIADGEKFACKVISQEYLIENKLVESFKREVENFGKLDHPNILRLIDFLS--DEKL-IYMIMTLCDAGDLHGYIADH--GP
|..   || ||.|.| |.. .  |.|.| |..  . | ...  ....||.|   ||||||| .| .     .|.  ||.|| ..  |.|..||  |  |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FSEYQAKAIFKQIISAVDYLHSLNIAHRDLKPENILLEKDM--TVKLADFGFSRETVGNQLMKTKCGSPIYTAPEIITQPEYDGKMADMWSVGVILFVML
 .|  |..||.||.||| |.|| ||.|||.||||||. ...   .|..|||||..   .|. .| ||.| | ||||. . .|||. .|.|| ||.|..|.
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGKIPWESST-NETQLFFQIRTARFHIPENINPIAAKLIGELMVPQPEMRCTAKEVLTHPWI
.|. |.. .| .. .|...|.. ...|| .. . . .||  |... ||.| |..|.. |||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
S_TKc 94652.m00102.AA S_TKc 20-273 34 6.8e-96 325.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-273
Range on HMM: 1-231/231
Sequence Identity: 34% (92 aa)

YRFESIIGRGSFAVVVLVTRIADGEKFACKVISQEYLIENKLVESFKREVENFGKLDHPNILRLIDFLSDEKLIYMIMTLCDA--GDLHGYIADHGP---
|..  .||.|.|..| ... . .|...|.|.|.          |...||..   | .|||| .|.|.  | . .||.| .||   |||. || ..|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSEYQAKAIFKQIISAVDYLHSLNIAHRDLKPENILLEKDMTVKLADFGFSRETVGNQLMKTKCGSPIYTAPEIITQPEYDGKMADMWSVGVILFVM
   |.| .|. ...||..|..|.||..| ||||||||||| .  ..|..|||..|.       .| ||.| | |||..    |... .|.||.|.||. |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LTGKIPWESSTNETQLFFQIRTARFHIPENINPIAAKLIGELMVPQPEMRCTAKEVLT-------HPWI
|.|. |..   .. ..| .|.           | |  .|  ...  || | || |.|.       |||.
LCGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94652.m00102.AA AMPK 20-273 37 1e-91 272.54 In-house 1-254 (254) Show / Hide 
Range on Protein: 20-273
Range on HMM: 1-254/254
Sequence Identity: 37% (95 aa)

YRFESIIGRGSFAVVVLVTRIADGEKFACKVISQEYLIENKLVESFKREVENFGKLDHPNILRLIDFL-SDEKLIYMIMTLCDAGDLHGYIADHGPFSEY
|  .  ||.|.|  | . | |  ||| | |..  . ... . ||. .||...  .. ||.| .| . . . .. |.|.|     |.|  ||. ||  .| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

QAKAIFKQIISAVDYLHSLNIAHRDLKPENILLEKDMTVKLADFGFSRETVGNQLMKTKCGSPIYTAPEIITQPEYDGKMADMWSVGVILFVMLTGKIPW
.|.  |.||||.|.|.| ..|.||||||||.|| ... .|..||| |     ... || |||| | |||.|.   | |   | || ||||..|| |. | 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

ESSTNETQLFFQIRTARFHIPENINPIAAKLIGELMVPQPEMRCTAKEVLTHPWI
. . | ..|.  |.  .. ||....| |. || ..  . |. | | ...  ||| 
DDE-NTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 94652.m00102.AA Pkinase 20-273 32 6.6e-91 313.11 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-273
Range on HMM: 1-293/293
Sequence Identity: 32% (95 aa)

YRFESIIGRGSFAVVVLVTRIADGEKFACKVISQEYLIENKLVESFK-REVENFGKLDHPNILRLIDFLSDEKLIYMIMTLCDAG----DLHGYIA--DH
|.....||.|||..| . ... .|...|.|.|. .   ..|... .. .|..   .|.||||.||.|.  |.. |||.| .|. |    ||. ||   .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPF--SEYQAKAIFKQIISAVDYLHSLNIAHRDLKPENILLEKDMTV----KLADFGFSRE--TVGNQLMKTKCGSPIYTAPEIITQPEYDGKMADMWSV
|.|  || ..| ...||.....|.|| .| ||||||||||. .....    |..|||...   .  |. |.| ||.| | |||.|   .|.|. .||||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILFVMLTGKIPWESS-----TNETQLFFQIRTARFHIPE---------------------NINPIAAKLIGELMVPQPEMRCTAKEVLTHPWI
|.||. ||.|. |. ..      .. |....|. ...| ..                     |... . ..|  .  . |. |.||...| |||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 94652.m00102.AA ULK 20-273 27 4.6e-79 268.97 In-house 1-329 (329) Show / Hide 
Range on Protein: 20-273
Range on HMM: 1-329/329
Sequence Identity: 27% (90 aa)

YRFESIIGRGSFAVVVLVTRIAD----GEKFACKVISQEYLIENK-------LVESFKREVENFGKLD--------HPNILRLIDFLSDE--KLIYMIMT
|    ..| |||..|   . . .    .||.|||.|.........       . ...|.|...  ||.        |||| .|.|.. .   . ||.|| 
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCDAGDLHGYIADHGP----------FSEYQAKAIFKQIISAVDYLHSLNIAHRDLKPENILLEKD------------MTVKLADFGFSRE-TVG---NQ
.|. |||  ||  ...          .|| .|. .||||...  .||. || |||.||.|||. ..            ...|.|||||..  . .   .|
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LMKTKC------GSPIYTAPEIIT----QPEYDGKMADMWSVGVILFVMLTGKIPWESS-TNET-----QLFFQ-------IRTARFHIP-----ENINP
.|.|        |.|.| ||.|.     | .|. . .|.||.|.|.. ||.|| |.... . .      .|. .       |..  . .|      .| |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

IAAKLIGELMVPQPEMRCTAKEVLTHPWI
    ||  ... ... |..  |.. |||.
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 94652.m00102.AA Ciliate-E2 20-273 24 2e-78 266.85 In-house 1-365 (365) Show / Hide 
Range on Protein: 20-273
Range on HMM: 1-365/365
Sequence Identity: 24% (91 aa)

YRFESIIGRGSFAVVVLVTRIADGEKFA-----------------------CKVISQEYLIENKLVESFKREVENFG-----------KLDHPNILRLID
| |  .||.|.|..| ..... ....||                        |....  ... | ...  ||..  .           .|.||||.....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FYKKINEKNILEQLNHPNIIKMYE

FLS--DEKLIYMIMTLCDAGDLHGYIA------------DHGPFSEYQAKAIFKQIIS---------------AVDYLHSLN-IAHRDLKPENILLEKDM
.    |.. ||..| .|. |||  ||             | ..|.|...| |.|||..               |. |||| | | |||.||||||.    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

TVKLADFGFSRETVGN--------------------------------QLMKTKCGSPIYTAPEIITQPEYDG--------KMADMWSVGVILFVMLTGK
 .|..|||.|..   .                                .. .| ||.| | ||||.   .||.        ...|.||.||||. ||.||
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

IPWESSTNETQLFFQIRTARFH-------------IPENINPIAAKLIGE----LMVPQPEMRCT-AKEVLTHPWI
 |.     . ..  .|.   ..             ..... . .  ||      ... .|| | | ....| |||.
PPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 94652.m00102.AA CAMK-Unique 20-273 25 2e-78 258.44 In-house 1-363 (363) Show / Hide 
Range on Protein: 20-273
Range on HMM: 1-363/363
Sequence Identity: 25% (92 aa)

YRFESIIGRGSFAVVVLVTRIADGEKFACKVISQEYLIENKLVE-----------------SFKREVENFGKLDHPNILRLIDF----LSDEK-------
|..  ||| |.| .|  .. .. | |.|||..  ..  ..|...                 ..|||..   ..|||||..| |.      |.|       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------LIYMIMTLCDAGDLHGYIAD--------------------HGPFSE--YQAKAIFKQIISAVDYLHSLNIAHRDLKPENILLEKD-------
         .|..| .|..|||  .|..                     |.|||  ...  |. .. ||| |.||..| |||||.|||.. .        
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

---------MTVKLADFGFSRETVGNQLMK---TKCGSPIYTAP--------------EIITQPEYDGKMA---DMWSVGVILFVMLTGKIPWESSTNET
           .||.||| ...  .|.      | ||.|.| ||              |.| .. ||..     | || |||.. ||.|. | ...... 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------QLFFQIRTARF-HIPENINPI-------AAKLIGELMVPQPEMRCTAKEVLTHPWI
        .|  |. ... . ..  . .       |  ..  .|.  |  | .||| | |.||
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 94652.m00102.AA ULK 20-273 28 2.2e-78 266.71 In-house 1-324 (324) Show / Hide 
Range on Protein: 20-273
Range on HMM: 1-324/324
Sequence Identity: 28% (92 aa)

YRFESIIGRGSFAVVVLVTR-IAD---GEKFACKVISQEYLIENKLV-------ESFKREVENFGKLD---HPN--ILRLIDFLSDE--KLIYMIMTLCD
|    ..| |||.|.|   | . .   ....|||.|.. .....|.        ...|.|...  ||.   |||  | .|.|.. .   . ||.|| .|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

AGDLHGYIADHGP---------FSEYQAKAIFKQIISAVDYLHSLNIAHRDLKPENILLEKD------------MTVKLADFGFSRE-TVGN---QLMKT
 |||  ||  ...         .|| .|. .||||...  .||. || |||.||.|||. ..             ..|.|||||..    .|   |...|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

KC------GSPIYTAPEIIT----QPEYDGKMADMWSVGVILFVMLTGKIPWESS-TNET----QLFFQ-------IRTARFHIP-----ENINPIAAKL
 .      |.|.| ||.|.     | .|. . .|.||.|.|.. ||.|| |..|. ...     .|  .       |..  . .|      .| |    |
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

IGELMVPQPEMRCTAKEVLTHPWI
|  ... ... |..  |.. |||.
IRRMLQYDEKDRISWEEIFNHPWF
Kinase 94652.m00102.AA Ciliate-E2-Unclassified 20-273 24 1.1e-73 251.17 In-house 1-352 (352) Show / Hide 
Range on Protein: 20-273
Range on HMM: 1-352/352
Sequence Identity: 24% (88 aa)

YRFESIIGRGSFAVVVLVTRIADGEKF-----ACKVISQEYLIE-------NKLVESFKREVENFGK------------LDHPNILRLIDFLSDEKLIYM
|..  .||.|.|..| .. .. .. ..     ..|....  ..        |.. | ....  .. .            ..||.|.....   |.. ||.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IMTLCDAGDLHGYIADHGP-----------------FSEYQAK-----AIFKQIISAVDYLHSLN-IAHRDLKPENILLEKDM---TVKLADFGFSR---
.| .|. |||. || . .                  |.|.|||      .|.||... .|||. | | |||.||||||. ...    .|..|||.|.   
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----ETVGN----------QLMKTKCGSPIYT----APEIITQPEYDG---KMADMWSVGVILFVMLTGKIPWESSTNET---------------QLFFQ
    .. .|          |.|.|.||.|.|     |||.. . .||.   ...|.||.||||. ||.|. | .. . |                ||. .
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

IRTARFHIPE--------NINPIAAKLIG----ELMVPQPEMRCTAKEVLTHPWI
|    . .|.        ...| |. .|      ... .|. | |....| |||.
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 94652.m00102.AA QIK 20-273 36 4.4e-72 245.79 In-house 1-272 (272) Show / Hide 
Range on Protein: 20-273
Range on HMM: 1-272/272
Sequence Identity: 36% (99 aa)

YRFESIIGRGSFAVVVLVTRIADGEKFACKVISQEYLIENKLVESFKREVENFGKLDHPNILRLIDFLSDEKLIYMIMTLCDAGDLHGYIADHGP-----
|  |  ||.| |||| | . .   .| | |.|  . | |  | .  .|||.    |.||.| .| . .  .. .|...  |  |..  |.. ||      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENL-QKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------FSEYQAKAIFKQIISAVDYLHSLNIAHRDLKPENILLEKDMTVKLADFGFSRETVGNQLMKTKCGSPIYTAPEIITQPEYDGKMA
                .| .|. .|.||.|||.|.|..||.||||| ||||| ..| .|.||||||    . ||..| |||| | |||.    ||||  .
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DMWSVGVILFVMLTGKIPWESSTNETQLFFQIRTARFHIPENINPIAAKLIGELMVPQPEMRCTAKEVLTHPWI
| || ||.|.|. .|..|  ..|  ..|   .   .| ||  .    ..||   .|  || | | . .. |.|.
DIWSMGVVLYVLVCGALPFDGKTL-QNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 94652.m00102.AA TyrKc 20-273 24 1.7e-17 60.11 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-273
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

YRFESIIGRGSFAVVVLVTRIADGEKFACKVISQEYLIENKLVESFKREVENFGKL--DHPNILRLIDFLSDE-------KLIYMIMTLCDAGDLHGYIA
 ... ..|.| | .|.. | .   .. | |..  .       .| | || .   ||  .||||.||.   ...       . ....| ... |||. |. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

DHGP-FSEYQAKAIFKQIISAVDYLHSLNIAHRDLKPENILLEKDMTVKLADFGFSRETVGN-------QLMKTK---CG---SPI-YTAPEIITQPEYD
.|.| ..  .   .  || .  .|||| |. ||||   |.|. .. ||| .||| ||.           .  ..|   .|    ||  .||| |   .. 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GKMADMWSVGVILFVMLT-GKIPWESS----TNETQLFFQIRTA-RFHIPEN--------INPIAAKLIGELMVPQPEMRCTAKEVLTHPWI
    | || || .. ..| |. |..       . .... ....  |  .|.|          .   ... .    .||.|.| .|.  |  .
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 94652.m00102.AA Pkinase_Tyr 20-219 28 1.8e-16 56.44 Pfam 1-217 (270) Show / Hide 
Range on Protein: 20-219
Range on HMM: 1-217/270
Sequence Identity: 28% (62 aa)

YRFESIIGRGSFAVVVLVTRI----ADGEKFACKVISQEYLIENK-LVESFKREVENFGKL-DHPNILRLIDFLS-DEKL--IYMIMTLCDAGDLHGYIA
 .|   .|.|.| .|.. |       .. . | |..  |.  .   . |.| ||..   .| .||||.||.   . ...   ||..| ..  |||. |  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

DH----GPFSEYQAKAIFKQIISAVDYLHSLNIAHRDLKPENILLEKDMTVKLADFGFSRET--VGNQ-LMKTKCGSPI-YTAPEIITQPEYDGKMADMW
.|    .|..  .   .  || .. .||.| |. ||||   |.|......|| .||| .|     ..   .....  ||  .||| |   ..  |  | |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTK-SDVW

SVGVILFVMLT-GKIP-WE
| || .. ..| |..| ..
SFGVLMWEIFTYGEQPTYP