Gene 82761.m00480 (T.vaginalis)
82761.m00480
Species: T.vaginalis
Alias: 82761.m00480, TvagK0449
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
82761.m00480.AA | Protein | None | 417 | None | Fasta, JSON |
82761.m00480.kin_dom | Protein Kinase Domain | None | 207 | None | Fasta, JSON |
Protein domains of 82761.m00480.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 82761.m00480.AA | CK1-Unclassified | 18-249 | 49 | 2.1e-131 | 390.03 | In-house | 1-244 (244) | Show / Hide |
Range on Protein: 18-249 Range on HMM: 1-244/244 Sequence Identity: 49% (121 aa) YQVIRRIGAGSFGAIYEVQHVETGKIYAVKLERFNT-SPQLQMEHKLYTLLDGAI-------AISRVYDFWVDEK--WRAMIMDRLGCSLGYYFRKCGKI |.||..||.|||| ||.. ...|.. .|.|||. |. .|||. | |... | . | ..| . .|. |.|| || || ..| .|.. YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNRK LSLKTTLMVAIQMISRLEYLHERCLIHRDIKPENFVFG-VGKNSNLLYIIDLGLAKNYRGF-KNYQHINYAEDRGLAGTARYVSINVHLGVEQSRRDDLE .||||.|| | |||.|.||||....|||||||.||. | |||.. .||||.||.| |. |. .|| | |...| ||||| ||| |||.||||||||| FSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLE SVGYVLISLVKGRLPWQEIEAGSKGDQNDNISHAKMNTPVETLC |.||||| . ||.|||| | | .| . . | ||.|||| || SLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC |
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Kinase | 82761.m00480.AA | CK1 | 18-275 | 47 | 2.8e-128 | 432.46 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 18-275 Range on HMM: 1-271/271 Sequence Identity: 47% (128 aa) YQVIRRIGAGSFGAIYEVQHVETGKI--YAVKLERFNTS-PQLQMEHKLYTLLDG------AIAISRVYDFWVD--EKWRAMIMDRLGCSLGYYFRKCGK |.|.|.||.|||| ||.. .. .|. .|.|||. .. |||. | |.|. | | .. | ..| . . .. .|.|| || || .| .|.. YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCNR ILSLKTTLMVAIQMISRLEYLHERCLIHRDIKPENFVFGV-GKNSNLLYIIDLGLAKNYRGFKNYQHINYAEDRGLAGTARYVSINVHLGVEQSRRDDLE .||||.||.| |||.|.||.|....|||||||.||. |. ||... .|||| |||| || |. ||| | |...| ||||| ||| |||.|||||||.| KFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDME SVGYVLISLVKGRLPWQEIEAGSKGDQNDNISHAKMNTPVETLCEG-LPNQFQTYMQRVRDFRFDERPQYS |.||||. . .| |||| . | .| . . |. ||.||||.||.| .||.|..|.. .| .|.|.| | SLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM |
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Kinase | 82761.m00480.AA | CK1-D | 18-277 | 49 | 1.2e-107 | 363.88 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 18-277 Range on HMM: 1-261/261 Sequence Identity: 49% (129 aa) YQVIRRIGAGSFGAIYEVQHVETGKIYAVKLERFNTS-PQLQMEHKLYTLLDGAIAISRVYDFWVDEKWRAMIMDRLGCSLGYYFRKCGKILSLKTTLMV | . |.||.|||| || . ..|. |.||| | |||..| |.| .. | | | .. . . . .|.|| || || | |.. |||| ||. YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRKFSLKTVLML AIQMISRLEYLHERCLIHRDIKPENFVFGVGKNSNLLYIIDLGLAKNYRGFKNYQHINYAEDRGLAGTARYVSINVHLGVEQSRRDDLESVGYVLISLVK | |||.|.||.| | |||||||.||. |.|| |. |||| |||| || .. ||| | |.. | ||||| ||| |.|.||||||||||.||||. . ADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNR GRLPWQEIEAGSKGDQNDNISHAKMNTPVETLCEGLPNQFQTYMQRVRDFRFDERPQYSYL | |||| . | | .. . |. ||.|...|||.|.|..||.|| .| ..||..| |.|| GSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL |
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Kinase | 82761.m00480.AA | CK1-A | 18-277 | 47 | 6.4e-102 | 344.9 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 18-277 Range on HMM: 1-261/261 Sequence Identity: 47% (125 aa) YQVIRRIGAGSFGAIYEVQHVETGKIYAVKLERFNTS-PQLQMEHKLYTLLDGAIAISRVYDFWVDEKWRAMIMDRLGCSLGYYFRKCGKILSLKTTLMV |...|.||.|||| || .. |. |.|.|. . ||| | |.|..|.|.. | .. . . . .|.|| || || | | . ..|| ||. YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVLML AIQMISRLEYLHERCLIHRDIKPENFVFGVGKNSNLLYIIDLGLAKNYRGFKNYQHINYAEDRGLAGTARYVSINVHLGVEQSRRDDLESVGYVLISLVK | |||.|.||.||.. |||||||.||. |.|. | |..|| |||| || . ||| | ||. | ||||| ||| |||.|||||||.||.|||.. . ADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNR GRLPWQEIEAGSKGDQNDNISHAKMNTPVETLCEGLPNQFQTYMQRVRDFRFDERPQYSYL |.|||| ..| | . . || || ||.| || | | .| ||. .|. ||.| | | || GKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL |
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Kinase | 82761.m00480.AA | CK1 | 18-277 | 31 | 3.4e-97 | 329.21 | In-house | 1-339 (339) | Show / Hide |
Range on Protein: 18-277 Range on HMM: 1-339/339 Sequence Identity: 31% (107 aa) YQVIRRIGAGSFG-AIYEV-----QHVETG-----KIYAVKLER-FNT--SPQLQMEHKLYTLLDGA---------------------IAISRVYDFWVD ..|.. || |.|| .||.| .... . ||.|.|. . .|||..|...| .| | . . ..| . .| WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED EKWRAMIMDRLGCSLGYYFR---KCGKILSLKTTLMVAIQMISRLEYLHERCLIHRDIKPENFVFGV------GKNSN--------LLYIIDLGLAK-NY .... |.|..|| .|. ... |.. .|.||.||.||||...|||.|... |||||||.||..|. ||. . .|.|| |.|. | DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKH-HHEWNNEHRQVYMIDFGMARRKY RGF-----------KNYQHINYAE---DRGLAG-TARYVSINVHLGVEQSRRDDLESVGYVLISLVKGR--LPWQEIEAGSK------GDQNDNISHA-K | |..||. . | .|. | ||||.|||.|||.||.|||||.|..|.|| ..|| |||| ... .| ... .. . | RDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKK MNTPVETLCEG-----LPNQFQTYMQRVRDFRFDERPQYSYL |.||.. ||.. .| .| ..|. .| ....|| | .. MSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI |
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Kinase | 82761.m00480.AA | CK1-G | 18-277 | 42 | 1.9e-90 | 306.75 | In-house | 1-266 (266) | Show / Hide |
Range on Protein: 18-277 Range on HMM: 1-266/266 Sequence Identity: 42% (114 aa) YQVIRRIGAGSFGAIYEVQHVETGKIYAVKLERFNTS-PQLQMEHKLYTLLDGAI-AISRVYDFWVDEKWRAMIMDRLGCSLGYYFRKCGKILSLKTTLM |.| ..|| |.|| ..| . . .. |.|.| . |||. | . | .| |. | .|| | |. .|.|| || || | |. |.||..| YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWCDRKFSVKTVCM VAIQMISRLEYLHERCLIHRDIKPENFVFG--VGKNSNLLYIIDLGLAKNYRGFKNYQHINYAEDRGLAGTARYVSINVHLGVEQSRRDDLESVGYVLIS ||||||.|.||.|.. || ||.||.|| | |. ....||| |.|| |. . ||| | | . | ||||| ||| ||| |||||||.|. | . . VAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFMY LVKGRLPWQEIEAGSKGDQNDNISHAKMNTPVETLCEG--LPNQFQTYMQRVRDFRFDERPQYSYL | |||| | . . | | .|..| ||.. .| || ||.. || |.| | | || FLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL |
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Kinase | 82761.m00480.AA | TTBKL | 18-281 | 25 | 2.2e-52 | 175.19 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 18-281 Range on HMM: 1-288/288 Sequence Identity: 25% (76 aa) YQVIRRIGAGSFGAIYEVQHVETGKIYAVKLERFNT----SPQLQMEHKLYTLLD--GAIAISRVYDFWVDEKWRAMIMDRLGCSLGYYFRKCGKI--LS ..... || | ||..|.| ... | .|.. | .|. . ..||... ..| |.. . .... . .. . |.| .| .|. .. .| WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS LKTTLMVAIQMISRLEYLHERCLIHRDIKPENFVFGVGKN----SNLLYIIDLGLAKNYRGFKN----------YQHINYAE---DRGLAGTARYVSINV |.. ..|| . | ..|. . ||||.|| |...|. .. . ..|.|| |.|. |. . . ... . .. || ||.|.|. DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM HLGVEQSRRDDLESVGYVLISLVKGRLPWQEIEAGSKGDQNDNISHAKMNTPVETLCEG------LPNQFQTYMQRVRDFRFDERPQYSYLRGLF |.. ||.| ||| |. |..| |..| |||. .| . ..| |.|.|. |.|. . .| .| |. .| |. .|| |.... .| HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNME------DKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF |
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Kinase | 82761.m00480.AA | Pkinase | 18-235 | 26 | 2.3e-35 | 126.14 | Pfam | 1-224 (293) | Show / Hide |
Range on Protein: 18-235 Range on HMM: 1-224/293 Sequence Identity: 26% (62 aa) YQVIRRIGAGSFGAIYEVQHVETGKIYAVK-LERFNTSPQLQM------EHKLYTLLDGAIAISRVYDFWVDEKWRAMIMDRLGC-----SLGYYFR-KC |...|.||.|||| |. .|. ||||.||| ... ..... .. | .. |. | | ||.. |... |.|. ... .| | . . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPN-IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR GKIL--SLKTTLMVAIQMISRLEYLHERCLIHRDIKPENFVFGVGKNSNL---LYIIDLGLAKNYRGFKNYQHINYAEDRGLAGTARYVSINVHL-GVEQ .. . | .. ... |... |||.|.. ||||.||||. . .| .. . |.| |||| .. . |. ...|| .|.. |.. | . HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRGGQYY SRRDDLESVGYVLISLVKGRLPWQEIEAGSKGDQNDN ... | |.| .|. .. ||.|... .... ... GPKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-HDQM |
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Kinase | 82761.m00480.AA | TTBK | 18-277 | 30 | 1.7e-32 | 112.14 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 18-277 Range on HMM: 1-257/257 Sequence Identity: 30% (82 aa) YQVIRRIGAGSFGAIYEVQHVETG-KIYAVKLERFNTSPQ-LQMEHKLYTLLDGAIAISRVYDFWVDEKWRAMIMDRLGCSLGYYFRKCGK-ILSLKTTL .|...|| | || ||| . . . |.|.| .. | |.|| | | . | . ..|. |.|. .| .| || . || ||| WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTL MVAIQMISRLEYLHERCLIHRDIKPENFVFG-VGKNSNLLYIIDLGLAKNYRGFKNYQHINYA-EDRGLAGTARYVSINVHLGVEQSRRDDLESVGYVLI . .|.. .| |. |||||| || | . .. . |..| ||| | . . | | ||.|| ||| |. | |.||| |. |.|. RLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQY--TNACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLV SLVKGRLPWQEIEAGSKGDQNDNISHAKMNTPVETLCEGLPNQFQTYMQRVRDFRFDERPQYSYL |.| ||| | | . . | | . .| .|...|. .. . .|| | . EFVQGQLPWRKIK------DKDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI |
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Kinase | 82761.m00480.AA | Worm6 | 88-277 | 25 | 2.2e-31 | 109.9 | In-house | 80-279 (279) | Show / Hide |
Range on Protein: 88-277 Range on HMM: 80-279/279 Sequence Identity: 25% (52 aa) MIMDRLGCSLGYYFRKC-GKILSLKTTLMVAIQMISRLEYLHERCLIHRDIKPENFVFGV-----GKNSNLLYIIDLGLAK--NYRGFKNYQHINYAEDR ..| .| .|. . . . .. .|. |.| .|||.. ..| || ||||.|| || .|. ... .|..| |... |.. .| . ... IVMTLVGKNLWDLRKNRPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTAC GLAGTARYVSINVHLGVEQSRRDDLESVGYVLISLVKGRLPWQEIEAGSKGDQNDN-ISHAKMNTP----VETLCEGLPN-QFQTYMQRVRDFRFDERPQ | || || ... | | ||.|.||.|| |... ...|.|||. . |...... . ...... . . .. | .|. |... .. .|| GFRGTVRYAPLACHKGQEQCRKDDCESWFYMMVEMIVGCLPWRHM----KDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPD YSYL | .. YKFI |
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Kinase | 82761.m00480.AA | VRK | 82-221 | 40 | 3.4e-23 | 71.51 | In-house | 100-240 (284) | Show / Hide |
Range on Protein: 82-221 Range on HMM: 100-240/284 Sequence Identity: 40% (58 aa) DEKWRAMIMDRLGCSLGYYFR-KCGKILSLKTTLMVAIQMISRLEYLHERCLIHRDIKPENFVFGVGKNSNLLYIIDLGLAKNYRGFKNY-QHINYAED- .|| | |.|.|.| .| .|. .| || | .|..|. |||||| | ||| .| | || . | .| ||| || ... | | || GEKYRFMVMPRFGRDLQKIYEDQNGHRFSMKTVLQLACRMLDVLEYLHENEYVHGDIKAANILLGFEKNPDQVYLVDYGLA--YR-YCPNGKHRQYKEDP -RGLAGTARYVSINVHLGVEQSRRDDLESVGYVLISLVKGRLPW |. || . |. |.|. ||| |||. || .. | ||| RRCHNGTCEFTSMDAHKGCAPSRRSDLEILGYCMMMWLYGYLPW |
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Kinase | 82761.m00480.AA | S_TKc | 18-299 | 18 | 6.6e-19 | 70.05 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 18-299 Range on HMM: 1-231/231 Sequence Identity: 18% (56 aa) YQVIRRIGAGSFGAIYEVQHVETGKIYAVKLERFNTSPQLQMEHKLYTLLDGAIAISRVYDFWVDEKWRAMIMDRLGC---SLGYYFRKCGKI-----LS |...| || |.|| | ..|..||.|.|.| . ... | .. . | . ||...| . |.|. .. .| | .|.|. .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP LKTTLMVAIQMISRLEYLHERCLIHRDIKPENFVFGVGKNSNLLYIIDLGLAKNYRGFKNYQHINYAEDRGLAGTARYVSINVHLGVEQSR-RDDLESVG .. .. |... |||.|.. ||||.|||| . . |.| |||. . . . || |.. | .. . | |.| E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG YVLISLVKGRLPWQEIEAGSKGDQNDNISHAKMNTPVETLCEGLPNQFQTYMQRVRDFRFDERPQYSYLRGLFYQLLST-----LNYAYDDK-------Y .|. .. |. |.. | . . . . . .. . ..| . . CILYEMLCGYPPFP---------QMQMMFKKIG--------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCH DWI |. PWF |
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Kinase | 82761.m00480.AA | Worm6 | 18-61 | 36 | 6.8e-13 | 42.89 | In-house | 1-49 (279) | Show / Hide |
Range on Protein: 18-61 Range on HMM: 1-49/279 Sequence Identity: 36% (18 aa) YQVIRRIGAGSFGAIYEVQHVETGK--IYAVKLER--FNTSPQ-LQMEH ..| . || |.|||.|.|.. ...| .|.|.|. | . | |.||. WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMEC |
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Kinase | 82761.m00480.AA | TyrKc | 18-281 | 14 | 0.000198 | -151.02 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 18-281 Range on HMM: 1-280/280 Sequence Identity: 14% (48 aa) YQVIRRIGAGSFGAIYEVQHVETGKIYAVKLERFNTSPQLQMEHKLYTLLDGAIAISRV--------------YDF-----WVDEKWRAMIMDRLGCSLG . .. .| | || .|. . ||| . .. . ... | ... . .. . | .|. | ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD-LK YYFRKCGKILSLKTTLMVAIQMISRLEYLHERCLIHRDIKPENFVFGVGKNSNLLYIIDLGLAKNYRGF------KNYQHINY---AE------------ | ||... |..|. | ..| . ||||....||||. | | .. | | ||... | | . . DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC -DRG--------------------LAGTARYV-------SINVHLGVEQSRRDDLESVGYVLISLVKGRLPWQEIEAGSKGDQNDNISHAKMNTPVETLC . | . .. . . |. |.| .| . .| .| INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MS-----------------------------------F EGLPNQFQTYMQRVRDFRFDERPQYSYLRGLF . | . |.. .. ..|| | .. .| VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | 82761.m00480.AA | VRK | 18-34 | 41 | 0.304946 | 0.24 | In-house | 1-17 (284) | Show / Hide |
Range on Protein: 18-34 Range on HMM: 1-17/284 Sequence Identity: 41% (7 aa) YQVIRRIGAGSFGAIYE . . . || | || ||. WRLGKPIGQGGFGCIYL |