Gene 95978.m00066 (T.vaginalis)
95978.m00066
Species: T.vaginalis
Alias: 95978.m00066, TvagK0125
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 95978.m00066.AA | Protein | None | 397 | None | Fasta, JSON |
| 95978.m00066.kin_dom | Protein Kinase Domain | None | 253 | None | Fasta, JSON |
Protein domains of 95978.m00066.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 95978.m00066.AA | CAMK | 19-266 | 24 | 3.5e-113 | 366.2 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 19-266
Range on HMM: 1-425/425
Sequence Identity: 24% (104 aa)
TIGTGAFSVVKLAYDEARK------------RYMACKIVPKSRLSS-------------------------PELEQRFEIEIKIFQQ-------LTHPGI
|.|.|.|..|||... . . |.||..|..|.. |. ..... ||.| .. | || |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
ITLYDLLKD-------------------DLNYYIFM---EFCPNGEL----FQHIVDE---------------GKLSEDETKTIVYQVFSVLSYIHSKGI
| ||. | | ..|..| |.|..||| |..||. |...|.|..... |. | . |.||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
AHRDLKPENLLLDEQ-----------------GHVKISDFGLSRFVGQ------------------------TGIANTPCGSPCYAS-PECVSG------
.||||||||.|||. . .||.|||..... . . .|.||.|.|.. || ..|
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
-------CPYNAFTSDVWSTGVIIYAMLTGQLPWTKR-------------NQTQLFQQIRRGEYT-IPKHLTP-----------------------DCQN
|| . .|.|| ||| |.||.| .|. |. .||..|..|.|. .|....| .|..
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
FIQGLMTVDITKRLTIEEALNHPWM
.|.....|| .||.|||..||||||
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 95978.m00066.AA | AMPK | 14-266 | 42 | 5.70000000001e-108 | 321.61 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 14-266 Range on HMM: 1-254/254 Sequence Identity: 42% (107 aa) YQIRGTIGTGAFSVVKLAYDEARKRYMACKIVPKSRLSSPELEQRFEIEIKIFQQLTHPGIITLYDLL-KDDLNYYIFMEFCPNGELFQHIVDEGKLSED |.| |||.|.| ||... . . . | || | .. . . .| . ||.| . ..|| || ||. . . ...||. ..|||| || |.|.|. YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER ETKTIVYQVFSVLSYIHSKGIAHRDLKPENLLLDEQGHVKISDFGLSRFVGQTGIANTPCGSPCYASPECVSGCPYNAFTSDVWSTGVIIYAMLTGQLPW |.. |. | ..|.| .|.||||||||||||.. ..|| ||||| | |||||||.|| .|| .|. |.||.||| |||| | || EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF TKRNQTQLFQQIRRGEYTIPKHLTPDCQNFIQGLMTVDITKRLTIEEALNHPWM |...|.. |. |||.|||.|.|.... |... .|| .||.||.. |||| DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | 95978.m00066.AA | CAMKL | 14-266 | 35 | 1.1e-103 | 331.82 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 14-266 Range on HMM: 1-297/297 Sequence Identity: 35% (106 aa) YQIRGTIGTGAFSVVKLAYD-EARKRYMACKIVPKSRLS-SPELEQR-----------FEIEIKIFQQLT---HPGIITLYDLLKDDLN------YYIFM |.| |.|.|.|..|||| . .. | ||. |.... | ... . ||.| ..| || || ||. . .. . .|..| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EFCPNGE--LFQHIVDE----GKLSEDETKTIVYQVFSVLSYIHSKGIAHRDLKPENLLLDEQG--HVKISDFGLSRFVG-Q----TGIANTPCGSPCYA | |..|| ||..|| . |...|.|.. . |. | ..|.||.||.|||.||||.||||.| .||.|||.| . . .| ||||.|. EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM SPECVSG--CPYNAFTSDVWSTGVIIYAMLTGQLPWTKR--------NQTQLFQQIRRGEYTIP--KHLTPDCQNFIQGLMTVDITKRLTIEEALNHPWM .|| ..| ||... |.|| ||| |||..|.||. |. |. .|..| | .| .|. ||...|.....|. .|| ||.. .||||| APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| S_TKc | 95978.m00066.AA | S_TKc | 14-266 | 34 | 3.3e-103 | 350.08 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 14-266 Range on HMM: 1-231/231 Sequence Identity: 34% (93 aa) YQIRGTIGTGAFSVVKLAYDEARKRYMACKIVPKSRLSSPELEQRFEIEIKIFQQLTHPGIITLYDLLKDDLNYYIFMEFCPN--GELFQHIVDEGK--- |.| .|| |||..|..... .|..|.||.. .... ||.| .. || |..||| | ..|..||.|.. |.||..|.. |. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---LSEDETKTIVYQVFSVLSYIHSKGIAHRDLKPENLLLDEQGHVKISDFGLSRFVGQTGIANTPCGSPCYASPECVSGCPYNAFTSDVWSTGVIIYAM ..| ... ..||... | |.||.|| ||||||||.|||| |.||.||||.|.. .| ||.| | .|| . .|. . .|.|| |.|.| | RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM LTGQLPWTKRNQTQLFQQIRRGEYTIPKHLTPDCQNFIQGLMTVDITKRLTIEEALN-------HPWM |.|. |. .. ..|..|. .|.. .||......| .||.|. |||. |||. LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 95978.m00066.AA | MARK | 14-266 | 39 | 2.5e-92 | 302.12 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 14-266 Range on HMM: 1-262/262 Sequence Identity: 39% (104 aa) YQIRGTIGTGAFSVVKLAYDEARKRYMACKIVPKSRLSSPELEQRFEIEIKIFQQLTHPGIITLYDLLK--DDLN-YYIFMEFCPNGELFQHIVDE--GK | . |||.|....|||| . .| | ||..| .|. |. . .. ||.| ..| || || |.. . . |. || ...|||...|. |. YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR LSEDETKTIVYQVFSVLSYIHSKGIAHRDLKPENLLLDEQG--HVKISDFGLSRFVGQTGIANTPCGSPCYASPECVSGCPYNAFTSDVWSTGVIIYAML |.|.|...| |. | ..| |||.|.|||.||||.|.||.| .||.|||.|. . || ||.| |..|| ... ||... |.|| ||. |.|. LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV TGQLPWTKRN--QTQLFQQIRRGEYTIPKHLTPDCQNFIQGLMTVDITKRLTIEEALNHPWM .|..|. . . .|...|.||.|.|| |. ..|.|.|| |.||. .| |||| ..|||| CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | 95978.m00066.AA | Pkinase | 14-266 | 32 | 8.8e-91 | 312.7 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 14-266 Range on HMM: 1-293/293 Sequence Identity: 32% (96 aa) YQIRGTIGTGAFSVVKLAYDEARKRYMACKIVPKSRLSSPELEQRFE-IEIKIFQQLTHPGIITLYDLLKDDLNYYIFMEFCPNG----ELFQHIV--DE |.| ..|| |.|..|..... . |.||..|.. .| ...... ||.| . | || |..||| |. ..|. ||.|..| .|| .| .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GKL--SEDETKTIVYQVFSVLSYIHSKGIAHRDLKPENLLLDEQGHV----KISDFGLSRF--VGQTGIANTPCGSPCYASPECVSGCPYNAFTSDVWST |.. ||.| | ..||... | |.||.|| ||||||||.|.|..||. ||.||||... . ..|.||.| |..|| . |..| .|.|| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVIIYAMLTGQLPWTKR------NQTQLFQQIRRGEYTIPKHLT---------------------PDCQNFIQGLMTVDITKRLTIEEALNHPWM |.|.| ||.|..|. . .| |....|..... . . ..|. || .. ..| .||.|.|..|.|||. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 95978.m00066.AA | QIK | 14-266 | 36 | 7.6e-85 | 288.19 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 14-266
Range on HMM: 1-272/272
Sequence Identity: 36% (100 aa)
YQIRGTIGTGAFSVVKLAYDEARKRYMACKIVPKSRLSSPELEQRFEIEIKIFQQLTHPGIITLYDLLKDDLNYYIFMEFCPNGELFQHIVDEGK-----
| | ||| | | ||||| | | ||. ||.| . .| |. . |..| .| || || ||. . | || .|.|.|||.| ... |.
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENL-QKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM
---------------LSEDETKTIVYQVFSVLSYIHSKGIAHRDLKPENLLLDEQGHVKISDFGLSRFVGQTGIANTPCGSPCYASPECVSGCPYNAFTS
..|.|.. . |. | | |...|.||||| ||.|||.. .|| |||.| . | .| |||| || || | |. .
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV
DVWSTGVIIYAMLTGQLPWTKRNQTQLFQQIRRGEYTIPKHLTPDCQNFIQGLMTVDITKRLTIEEALNHPWM
|.|| ||. |.. .| || . ..| | . | . || . ||. .| ..|| ..|.||. ..|.||
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
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| Kinase | 95978.m00066.AA | ULK | 14-266 | 26 | 4.5e-80 | 272.33 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 14-266 Range on HMM: 1-329/329 Sequence Identity: 26% (88 aa) YQIRGTIGTGAFSVVKLAYDEARK----RYMACKIVPKSRLSSPELEQR-------FEIEIKIFQQLT--------HPGIITLYDLLKDD--LNYYIFME |... .| |.| .| .... .| . |||...|. .. . || .. |||| ..| || |. ||| .... |.||.|| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME FCPNGELFQHIVDEGK----------LSEDETKTIVYQVFSVLSYIHSKGIAHRDLKPENLLLDE------------QGHVKISDFGLSRFVGQT----G .|. | |.| | .| |||.|.. . .| . . ..|...| |||.||.| |... .|..||.|||....| YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ IANTPC------GSPCYASPECVS----GCPYNAFTSDVWSTGVIIYAMLTGQLP---WTKRNQT-----QLFQQ-------IRRGEYTIP-----KHLT .. | |.| | .|. .. ..||. ...|.|| |.|.| ||.|. | | .. | .|... |. .| ... MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS PDCQNFIQGLMTVDITKRLTIEEALNHPWM |.|...|......| ..| ..|| .||||. PECKDLIRRMLQYDEKDRISWEELFNHPWF |
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| Kinase | 95978.m00066.AA | ULK | 14-266 | 27 | 7.6e-78 | 264.92 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 14-266 Range on HMM: 1-324/324 Sequence Identity: 27% (88 aa) YQIRGTIGTGAFS-VVKLAYDEAR---KRYMACKIVPKSRLSSPELE-------QRFEIEIKIFQQLT---HPG--IITLYDLLKDD--LNYYIFMEFCP |... .| |.| .| .... . | |||...|. .. ..| | .. ||.| ..| || |. ||| .... |.||.||.|. YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN NGELFQHIVDEGK---------LSEDETKTIVYQVFSVLSYIHSKGIAHRDLKPENLLLDE------------QGHVKISDFGLSRFVGQTG----IANT | |.| | .| |||.|.. . .| . . ..|...| |||.||.|.|. . .|..||.|||....| . . | GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT PC------GSPCYASPECVS----GCPYNAFTSDVWSTGVIIYAMLTGQLP---WTKRNQT----QLFQQ-------IRRGEYTIPK-----HLTPDCQN . |.| | .|. .. ..||. . .|.|| |.|.| ||.|. | | ...| .| .. |. .|| .. |.|.. CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD FIQGLMTVDITKRLTIEEALNHPWM .|......| ..| ..|| .||||. LIRRMLQYDEKDRISWEEIFNHPWF |
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| Kinase | 95978.m00066.AA | RSK | 14-266 | 28 | 1.1e-76 | 261.09 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 14-266 Range on HMM: 1-278/278 Sequence Identity: 28% (79 aa) YQIRGTIGTGAFSVVKLAYDEARKRYMACKIVPKSRLSSPELEQRFEI-EIKIFQQLT-HPGIITLYDLLKDDLNYYIFMEFCPNGELFQHIVDEGK--- . |..| |...... ... ... | |.. |. . . .| |..| . . || |.||.. .... |. ||.|. |||| |. |. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC LSEDETKTIVYQVFSVLSYIHSKGIAHRDLKPENLLLDE---QGHVKISDFGLSRF-VGQ-TGIANTPCGSPCYASPECVS----GCPYNAFTSDVWSTG .|||| . . ... . ....|..|| |||||||| |.|. .||.|..|||... . . .. ..|.|.. |. || . .. ... |.|| | FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDK-ACDWWSLG VIIYAMLTGQLPWTK---RNQTQLFQQIRRGE--YTIP--KHLTPDCQNFIQGLMTVDITKRLT-----IEEALNHPWM |..| ||||..| . |. .....|..|. |.| . |.......|......| |||. .|| ..|||. VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 95978.m00066.AA | Ciliate-E2 | 14-266 | 25 | 6.6e-76 | 258.48 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 14-266 Range on HMM: 1-365/365 Sequence Identity: 25% (98 aa) YQIRGTIGTGAFSVVKLAYD-EARKRY----------------------MACKIVPKSRLSSPELEQRFEIEIK----------IFQQLTHPGIITLYDL | . ||.|.|..|... . . .|.. | ||. |. . . . |.. ||. | .|| || || .|. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC LK--DDLNYYIFMEFCPNGELFQHIV------------DEGKLSEDETKTIVYQVFS---------------VLSYIHSKG-IAHRDLKPENLLLDEQGH . || |.|. ||.| |.||..| | ....| | |.| .|... | |.|||. | |||.||||.|. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----- VKISDFGLSRFVGQT--------------------------------GIANTPCGSPCYASPECVSGCPYNA--------FTSDVWSTGVIIYAMLTGQL .||.|||||... . ..|| ||.| | .|| ..| .|. . .|.|| |||.| ||.|.. IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP PWTKRNQTQLFQQIRRGEYTIP------------------KHLTPDCQNFIQG----LMTVDITKRLT-IEEALNHPWM |. .||| ... .| |.....|...|. .. .| ||.| .|..|||||. PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 95978.m00066.AA | Ciliate-E2-Unclassified | 14-266 | 26 | 2.9e-75 | 256.35 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 14-266
Range on HMM: 1-352/352
Sequence Identity: 26% (94 aa)
YQIRGTIGTGAFSVVKLAYDEARKRYMACKIVPKSRLSSPELEQRF--------EIEIK--------------IFQQLTHPGIITLYDLLKDDLNYYIFM
| | .||.|.|..|...... | | | |. |.. . . .. |...| |.... || |. ... .|. | || |
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM
EFCPNGELFQHIVDEGK-----------------LSEDETK-----TIVYQVFSVLSYIHSKG-IAHRDLKPENLLLDEQG---HVKISDFGLSRFVG--
|.|..|.|.|.| . .| ..| ..| .. .|. . |.|.|.|. | |||.||||.|.|..| ..||.|||.|.. .
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN
--------------QTGIANTPCGSPCYA----SPECVSGCPYNA---FTSDVWSTGVIIYAMLTGQLPWTKRNQTQ----------------LFQQIRR
. ...| ||.|.| .||. |. |. . .|.|| |||.|.||.|..| .|..| |.|.|
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ
GEYTIPK--------HLTPDCQNFIQ----GLMTVDITKRLTIEEALNHPWM
... .|| |. | ...||. .. ... ||.|.|..|||||.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 95978.m00066.AA | TyrKc | 14-266 | 22 | 2.7e-16 | 40.72 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 14-266 Range on HMM: 1-280/280 Sequence Identity: 22% (67 aa) YQIRGTIGTGAFSVVKLAYDEARKRYMACKIVPKSRLSSPELEQRFEIEIKIFQQL--THPGIITLYDLLKDD-------LNYYIFMEFCPNGELFQHIV . ..| ||| .| .. . | | . .. .. | |..| .| || |. || .. ..| ||..|.| | ... ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR DEGK-LSEDETKTIVYQVFSVLSYIHSKGIAHRDLKPENLLLDEQGHVKISDFGLSRFVGQT------GIANTP----CG---SPC-YASPECVSGCPYN . .. |. .. . .|. . .|.|||.. |||| | |..|...||||||||||... . .. .| | .||| . .. KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT AFTSDVWSTGVIIYAMLT-GQLPWTK-----RNQTQLFQQIRRGEYTIPKHL---------TPDCQNFIQGLMTVDITKRLTIEEALNHPWM . ||||| || .. ..| || |. . .........|.. . . ... . .. | .| | .| | . -TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | 95978.m00066.AA | Pkinase_Tyr | 14-228 | 26 | 9.1e-12 | 40.47 | Pfam | 1-233 (270) | Show / Hide |
Range on Protein: 14-228 Range on HMM: 1-233/270 Sequence Identity: 26% (64 aa) YQIRGTIGTGAFSVVKLAYDE----ARKRYMACKIVPKSRLSSPE-LEQRFEIEIKIFQQL-THPGIITLYDLLK-DDLN--YYIFMEFCPNGELFQHIV .. ..| ||| .|.... | | |.. | .... . . | |.|| || || |. || .. .|| ||..|.| | . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR D----EGKLSEDETKTIVYQVFSVLSYIHSKGIAHRDLKPENLLLDEQGHVKISDFGLSRFV-------GQTGIANTPCGSPCYASPECVSGCPYNAFTS . ...|. . . .|. . ..| .||.. |||| | |..|...|||.||||.| . ..| . | .||| . . .. | KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLP---IKWMAPECINYGKFT-TKS DVWSTGVIIYAMLT-GQLP-WTKRNQTQLFQQI-RRGE |||| || .. ..| |. | . ......| ..|. DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGY |
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