Gene 87130.m00073 (T.vaginalis)

87130.m00073

Species: T.vaginalis
Alias: TvagK0295, 87130.m00073
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
87130.m00073.AA Protein None 501 None Fasta, JSON
87130.m00073.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of 87130.m00073.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 87130.m00073.AA TKL 31-282 23 1.8e-69 237.1 In-house 1-364 (364) Show / Hide 
Range on Protein: 31-282
Range on HMM: 1-364/364
Sequence Identity: 23% (89 aa)

LGKGTYGNVWLGLNKYTGWN----------AAVKELITKE-----------------------LDQQQISFFKREVEILIKAK--DTFLLDLIGFTTKPP
.|.|..| |. |  |. ||.           ||| . ...                        . ..  .|..|.||... .     .. ..|. . ||
IGSGGFGEVYKG--KWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPP

--------------YSILTSYMQCGSLWDMIHNHPGTINGTQKTNIALGIAHAMRKLHA--------KNIIHRDLKSPNILLDEKVL-------------
              . | . |...|||.. .|         |. ..||.|| .|  ||.        ..||||||||.|||.||.               
CGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PKVADFGLGRFIGDDSAEKYMTK-----------------CIGTPIWMAPEQIHSD----------------TYDKSVDVYAFGMILYEMFTEVVPFKG
 .|..|||| ||.  ..  . . .                 ..||| ||||| .  .                .|....|||.||..|.|..|  .|...
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

YT-DVQI---------FQSVEKHLRPELPSVENQ-------PKQVQKLATLISLCWADDPSLRPSFEKIFKLF
|  . .|          . ..| |||..|.. ..       |   . .. |.  ||. ||. ||||..| | .
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 87130.m00073.AA TKL-Unique 27-282 29 8.9e-66 224.84 In-house 1-290 (290) Show / Hide 
Range on Protein: 27-282
Range on HMM: 1-290/290
Sequence Identity: 29% (88 aa)

FSRMLGKGTYGNVWLGLNKYTGWNAAVKELITKELDQQQISF-FKREVEILIKAK-DTFLLDLIGFTT----KPP-YSILTSYMQCGSLWDMIH------
|.  .| |.||.|  |  |. |   |.| .  .|.   .... |..|| .. | .   ... ..|...    .|| ..| ..|.. ||| | .|      
FWNKIGEGGYGQVYKG--KWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---NHPGTINGTQKTNIALGIAHAMRKLHAKN--IIHRDLKSPNILLDEK-----VLPKVADFGLGRFIGDDSAEKYMTK-------CIGTPIWMAPEQI
   |   ..|  |. ..|. || .|  || ..  ||||||||.|.|.|..     .  |..|||| .|   ...... ..        .|...||||| .
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

HS--DTYDKSVDVYAFGMILYEMFTEVV------PFKGYTDVQIFQSVEK---HLRPELPSVENQPKQVQKLATLISLCWADDPSLRPSFEKIFKLF
 .  ..|....|||.||..|.|..|  .      |..|... |... | .    .||..|  .. ||. ..   ||  ||..||| ||||. | .  
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIP--NHCPKEYRD---LIQQCWHHDPSQRPSFDEIIHRL
Kinase 87130.m00073.AA MLK 25-282 28 1e-53 184.66 In-house 1-291 (291) Show / Hide 
Range on Protein: 25-282
Range on HMM: 1-291/291
Sequence Identity: 28% (86 aa)

YQFSRMLGKGTYGNVWLGLNKYTGWN-----AAVKE-LITKELDQQQ----ISFFKREVEILIKAKDTF----LLDLIGFTTKPPYS--ILTSYMQCGSL
 ||.. .|.|..| ||.|  .. . .      |||.  .... | ..    .  |..|...| . .          . |  ..||.   |.. |...|||
IQFHEWIGSGSFGKVWKG--RWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSL

WDMIHNHPG-------------TINGTQKTNIALGIAHAMRKLHAKN---IIHRDLKSPNILLD-------EKVLPKVADFGLGRFIGDDSAEKYMTKCI
 . .|. ..             ..   .. |.|| .|..|  ||..    ||||||||.|||.|       ...| |..|||. |.. .    . |.. .
YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTL-KICDFGTSRDWHQMC--TNMMSNA

GTPIWMAPEQI---HSDTYDKSVDVYAFGMILYEMFTEVVPFK-GYTDVQI-FQSVEKHLRPELPSVENQPKQVQKLATLISLCWADDPSLRPSFEKIFK
||..||||| |    ...|....||. .|..|.||.|  ||.| .|   .| .. ....||| .||          .. |.. || .||. ||||  | .
GTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPST-----CPEHWKKLMKQCWNQDPHKRPSFRQIVQ

LF
 .
HL
S_TKc 87130.m00073.AA S_TKc 25-288 26 1.9e-53 184.8 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-288
Range on HMM: 1-231/231
Sequence Identity: 26% (72 aa)

YQFSRMLGKGTYGNVWLGLNKYTGWNAAVKELITKELDQQQISFFKREVEILIKAKDTFLLDLIGFTTKPPYSILTSYMQC--GSLWDMIHNHPG-----
|.. | .|||..| |... .| ||   |.|..            ..||..|| | .  ..  |...     . . . |.    |.| |.|.....     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

TINGTQKTNIALGIAHAMRKLHAKNIIHRDLKSPNILLDEKVLPKVADFGLGRFIGDDSAEKYMTKCIGTPIWMAPEQIHSDTYDK-SVDVYAFGMILYE
 ..  .   ..  |. |.  .| ..|||||||  ||||||    |..|||| |..         | ..||| .|||| .    |.| ..|....| ||||
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MFTEVVPFKGYTDVQIFQSVEKHLRPELPSVENQPKQVQKLATLISLCWADDPSLRPSFEKIFK---LFSRHVVA
|..   ||   .. ..|. .                  . .  .|. |.  ||. ||.  ....   .   |   
MLCGYPPFP--QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 87130.m00073.AA Dicty5 98-286 36 8.3e-49 166.11 In-house 76-260 (260) Show / Hide 
Range on Protein: 98-286
Range on HMM: 76-260/260
Sequence Identity: 36% (71 aa)

ILTSYMQCGSLWDMIHNHPG----TINGTQKTNIALGIAHAMRKLHAKNIIHRDLKSPNILLDEKVLPKVADFGLGRFIGDDSAEKYMTKCIGTPIWMAP
..| | . ||| ..           |   |.  .|..|| .|| || .||||||||| |.|. |    |. |||  ||.    . . ||  .||. |||.
HVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFV---DNRYHMTMHVGTQCWMAC

EQIHSDTYDKSVDVYAFGMILYEMFTEVVPFKGYTDVQIFQSVEKHLRPELPSVENQPKQVQ-KLATLISLCWADDPSLRPSFEKIFKLFSRHV
|   . .|.  .|||.|| .|.||||   |..  .   |   | |  ||..|      | ..   . ||  || . |..|||| .| | | . .
ELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIPVMVMKGERPTIP------KDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 87130.m00073.AA LRRK 84-284 33 5.2e-48 165.82 In-house 119-351 (351) Show / Hide 
Range on Protein: 84-284
Range on HMM: 119-351/351
Sequence Identity: 33% (79 aa)

LLDLIGFTTKPPYSILTSYMQCGSLWDMIHNHPGT--------INGTQKTNIALGIAHAMRKLHAKN--IIHRDLKSPNILL---D---------EKVLP
...|.||. . |. . . |...|.| . .||.  .        |. . |  ||| || .|..|| .|  |||||||||||||   .         . |  
IVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCA

KVADFGLGRFIGDDSAEKY-MTKCIGTPIWMAPEQIHSD---TYDKSVDVYAFGMILYEMFTEV-VPFKGYT-------DVQIFQSVEKHLRPELPSV-E
|.||||. | .   .  .    .| |.|.||||| .  .   .|.  ||.|.|||||.|  |    || ...         || . . . ||| .|.  .
KIADFGISR-MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYC

NQPKQVQKLATLISLCWADDPSLRPSFEKIFKLFSR
... .   . .|| .||. ||  ||.|..|.|  | 
PPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 87130.m00073.AA RAF 26-284 29 2.7e-45 144.64 In-house 2-282 (282) Show / Hide 
Range on Protein: 26-284
Range on HMM: 2-282/282
Sequence Identity: 29% (84 aa)

QFSRMLGKGTYGNVWLGLNKYTGWNAAVKELITKELDQQQISF---FKREVEILIKAKDTFLLDLIGFTTKPP---YSILTSYMQCGSLWDMIHNHPG--
. .   | | .| |. |  .. | ..||| |  ... ..|.     || || .. |      |   |...||    | | | . .  ||.  ||      
MVMTRIGSGSFGTVYRG--HWHG-DVAVKMLNVNDPTPEQMQADVFFKNEVAVYKKTRHCNILLFMGYMSKPQTNTYAIVTQWCEHSSLYHHIHVQETRE

TINGTQKTNIALGIAHAMRKLHAKNIIHRDLKSPNILLDEKVLPKVADFGLGRFIGDDS--AEKYMTKCIGTPIWMAPEQIH--------------SDTY
  .  .  .|.. .. .|  ||||||||||||| ||.|.| .  |. |||| .     |   .. .    .   ||||| |                  |
KFDMHWLIDISRQVCQGMDYLHAKNIIHRDLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQDENPY

DKSVDVYAFGMILYEMFTEVVPF---KGYTDVQIFQSVEKHLRPELPSVENQPKQVQKLATLISLCWADDPSLRPSFEKIFKLFSR
    |||.||...||. |.  |.       |  ||    . |||.|  | .  .  ...  |.. ||. ..  ||.|..| |    
SFQSDVYSFGIVMYELMTRHMPYGCHIWNRDQIIFMCGRGYLRPDLSKVRQ--DCPKAMHRLMEDCWKFQREERPLFQQILKRITV
Kinase 87130.m00073.AA Pkinase 25-282 25 1.2e-43 155.38 Pfam 1-293 (293) Show / Hide 
Range on Protein: 25-282
Range on HMM: 1-293/293
Sequence Identity: 25% (75 aa)

YQFSRMLGKGTYGNVWLGLNKYTGWNAAVKELITKELDQ-QQISFFK-REVEILIKAKDTFLLDLIGFT-TKPPYSILTSYMQCG----SLWDMIH--NH
|.. | .|.|..| |... .| ||   |||..  .. .  .... .. .|..|. . .  . . |...  .|. . . . |...|    .|.|.|.  .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PGTI--NGTQKTNIALGIAHAMRKLHAKNIIHRDLKSPNILLDEKVLP----KVADFGLGRFIGDDSAEKYMTKCIGTPIWMAPEQIH-SDTYDKSVDVY
 |..     .  .... |. ..  .|...|||||||. |||.|..  .    |..|||| ...        ||   ||| .|||| |  .  |...||..
-GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

AFGMILYEMFTEVVPFKGY----TDVQIFQSVEKHLRPELPSVENQPKQV------------------QKLATLISLCWADDPSLRPSFEKIFKL--F
..| |||||..   ||.|     . .   | ... ..|.|.. . ..  .                  . .  .|. |.. ||. ||..| |..   |
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 87130.m00073.AA Dicty4-Unclassified 26-282 33 2.9e-43 146.01 In-house 2-263 (263) Show / Hide 
Range on Protein: 26-282
Range on HMM: 2-263/263
Sequence Identity: 33% (90 aa)

QFSRMLGKGTYGNVWLGLNKYTGWNAAVKELITKELDQQ--QISFFKREVEILIKAKDTFLLDLIGFTTKP-----PYSILTSYMQCGSLWDMIH-----
|  . .|||    |  |  |  | . ||| .           |  ||.|||||       |. . |    |      . | .  |  | |  .||     
QIDQFIGKGHFSKVHKGNWK--GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSE

-NHPGTINGTQKTNIALGIAHAMRKLHAKNIIHRDLKSPNILLDEKVLPKVADFGLGRFIGDDSAEKYMTKCIGTPIWMAPEQIHSDTYDKSVDVYAFGM
 . |   . |    .|. ||  |  || .|.||||.|| |||.|     |.||||. | |   .    ||   ||| | .||      |    ||| ..|
QQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVI---DFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAM

ILYEMFTEVVPFKGYT-DVQIFQSV-EKHLRPELPSVENQPKQVQKLATLISLCWADDPSLRPSFEKIFKLF
.|||. |   |. .    . .  || .| |||..|.  | .  ..|   ||  || .||  ||....| .  
MLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPD--NCDNFWKK---LIKWCWHNDPNKRPTMNQIIQYL
Kinase 87130.m00073.AA TK 25-282 14 2e-42 139.53 In-house 1-486 (486) Show / Hide 
Range on Protein: 25-282
Range on HMM: 1-486/486
Sequence Identity: 14% (73 aa)

YQFSRMLGKGTYG---NVWLG-LNKYTGWNA------------------------AVKELI--TKELDQQQIS-FFK---------REVEILIKAK----
 .. . ||.| .|    |..| ..   .||.                        ||| |   . . .....  ...         .|.|.. . .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-DTFLLDLIG-FTTK------------PPYSILTSYMQCGS----LWDMIHNHPGT--------------------------------------------
    .. |.|  | .            .|. |.. ||..|.    | |  ......                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------INGTQKTNIALGIAHAMRKLHAK------NIIHRDLKSPNILLDEKVL-----------PKVADFGLGR
                               ..  |.  ... || .|. ||.|      |..||||   |.|..|.              |.||||| |
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----FIGDDSAEKYMTKCI------------------------GTPI---WMAPEQIHSDT---------YDKSVDVYAFGMILYEMFTEV-VPFKG-Y
        |.  ... ..                          |. .   ||||| . . .         .    ||..||  ..|.||   .|. |  
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TD---------VQIFQSVEK------------HLRPELPSVENQPKQV-----------QKLATLISLCWADDPSLRPSFEKIFKLF
..          .... ...              | ..|  .. | ..           . .. |.  ||. ||. ||.|. . . .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 87130.m00073.AA Ciliate-E2-Unclassified 25-280 20 4e-39 133.37 In-house 1-348 (352) Show / Hide 
Range on Protein: 25-280
Range on HMM: 1-348/352
Sequence Identity: 20% (71 aa)

YQFSRMLGKGTYGNVWLGLNKYTGWNAAVKELITKELDQQQISFFKREVEILIKAKDTF--------------------------LLDLIGFTTKPPYSI
| . . .|.| .| |..  .| ..  ..... . |  .. | .  . . ||. ..|  .                          . ..  |..|    |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

LTSYMQCGSLWDMIHNHPG---------------TINGTQKT------NIALGIAHAMRKLHAKN-IIHRDLKSPNILLDEKV---LPKVADFGLGRFIG
 . |.. |.||..| . ..                |   |..      ...  |  .  .|| || |||||.|  |||.|..     .|..|||. ....
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

DDSA-------------EKYMTKCIGTPIWM----APEQIHSDTYD----KSVDVYAFGMILYEMFTEVVPFKGYTDVQ---------------IFQSVE
...              .. |. ..|||. |    ||| . .  ||    ...|....|.||||| .   ||..... |               ....  
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

KHLRPELPSVEN--QPKQVQKLA-----TLISLCWADDPSLRPSFEKIFK
|   .. |. ..   ||.... |      |.. .   .|. |..||.|..
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN
Kinase 87130.m00073.AA LISK 98-221 32 2.7e-38 121.9 In-house 74-236 (296) Show / Hide 
Range on Protein: 98-221
Range on HMM: 74-236/296
Sequence Identity: 32% (54 aa)

ILTSYMQCGSLWDMIHNHPG---TINGTQKTNIALGIAHAMRKLHAKNIIHRDLKSPNILLDEK----VLPKVADFGLGRFIGDDS--------------
|.| |.. | | . ... .     .  .|. .|||.|| .|. ||..||||||||| |.|..|.       ||.|||. | . ...              
IVTEYINGGDLHQYLKDMDKHKIPLPWPQRVKIALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDP

------------------AEK-YMTKCIGTPIWMAPEQIHSDTYDKSVDVYAFGMILYEMFTEV
                   .|  || . |||.||||| .    || |.||. ||..| |. |.|
CMDNDMPMKRKIPKKCMNQRKRRMT-ICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRV
Kinase 87130.m00073.AA TyrKc 25-282 28 3.9e-37 130.59 SMART 1-280 (280) Show / Hide 
Range on Protein: 25-282
Range on HMM: 1-280/280
Sequence Identity: 28% (82 aa)

YQFSRMLGKGTYGNVWLGLNKYTGWNAAVKELITKELDQQQISFFKREVEILIKA--KDTFLLDLIGFTTK--------PPYSILTSYMQCGSLWDMIHN
 .. ..|| | .| |..|  |    . ||| |         .  | || .|. |   .   .. |.|  |.        .|. |.. ||  |.| | ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

HPGTINGTQKTNIALGIAHAMRKLHAKNIIHRDLKSPNILLDEKVLPKVADFGLGRFIGDD----SAEKYMTK-----CIG-TPI-WMAPEQIHSDTYDK
| ....  .. .... ||  |. || ||.|||||   |.|..|.   |..|||| |.|.||     ...| .|     . .  || ||||| |   ..  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

SVDVYAFGMILYEMFTE-VVPFKG-----YTDVQIFQSVEKHLRPELPSV-----ENQPKQVQKLATLISLCWADDPSLRPSFEKIFKLF
  ||..||  ..|.||    |  |      .. .... |..  |.. |          .   ... .... ||. ||. ||.|. | ..|
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF--VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 87130.m00073.AA Pkinase_Tyr 25-282 28 1.7e-36 124.23 Pfam 1-270 (270) Show / Hide 
Range on Protein: 25-282
Range on HMM: 1-270/270
Sequence Identity: 28% (80 aa)

YQFSRMLGKGTYGNVWLGLNK----YTGWNAAVKELITKELDQQQ--ISFFKREVEILIKA-KDTFLLDLIGFTT--KPP--YSILTSYMQCGSLWDMIH
 .| ..||.| .|.|..|  |     |.   ||| |     ...|  .  | ||..|. .  .   .. |.|  |  . |  . | . ||..|.| |  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

NH---PGTINGTQKTNIALGIAHAMRKLHAKNIIHRDLKSPNILLDEKVLPKVADFGLGRFIGDDSAE-KYMTKCIGTPI-WMAPEQIHSDTYDKSVDVY
.|   .. ..  .. .... || .|  |..||.|||||   |.|..|.   |..|||| | | .|.   .  ...   || ||||| |.   .    ||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVW

AFGMILYEMFT-EVVP-FKGYTDVQIFQSV-EKHLRPELPSVENQPKQVQKLATLISLCWADDPSLRPSFEKIFKLF
.||  ..|.||    | ..| .. .... . |.  | . |     ..  ... .|. .||. ||. ||.|. |   .
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCP-----ENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 87130.m00073.AA LISK 30-76 30 5.1e-05 12.02 In-house 1-50 (296) Show / Hide 
Range on Protein: 30-76
Range on HMM: 1-50/296
Sequence Identity: 30% (15 aa)

MLGKGTYGNVWLGLNKYTGWNAAVKELIT---KELDQQQISFFKREVEIL
 .||| .| |  |  ..||   |.|....   .  |   . |..|||...
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMM
Kinase 87130.m00073.AA LISK 268-282 46 0.004599 5.57 In-house 282-296 (296) Show / Hide 
Range on Protein: 268-282
Range on HMM: 282-296/296
Sequence Identity: 46% (7 aa)

DPSLRPSFEKIFKLF
||. ||||..| . .
DPKNRPSFKEIVQWL
Ank 87130.m00073.AA Ank 373-406 35 8e-06 25.19 Pfam 1-33 (33) Show / Hide 
Range on Protein: 373-406
Range on HMM: 1-33/33
Sequence Identity: 35% (12 aa)

KGYTPLHIAAILPSIPILSFLLDIKTINPNVQDD
 |.||||.|..  .. ....||. .  ..|.|||
DGFTPLHLACRCGHTEVVKMLLQ-HGADVNAQDD
Ank 87130.m00073.AA Ank 407-440 32 0.018833 13.1 Pfam 1-33 (33) Show / Hide 
Range on Protein: 407-440
Range on HMM: 1-33/33
Sequence Identity: 32% (11 aa)

KGRTPAMLAIKVHTLDVLIKLIEHPKTDVNIKDH
 |.|| .||..   ..|.  |..    |||..| 
DGFTPLHLACRCGHTEVVKMLLQ-HGADVNAQDD
Ank 87130.m00073.AA Ank 441-474 17 8.421789 3.54 Pfam 1-33 (33) Show / Hide 
Range on Protein: 441-474
Range on HMM: 1-33/33
Sequence Identity: 17% (6 aa)

SGHTIAHYSVIFNDIDALKVIMKNKNLDLKIVDK
 | |  |. .. .... .|  .. .. |. ..|.
DGFTPLHLACRCGHTEVVKMLLQ-HGADVNAQDD