Gene 95054.m00081 (T.vaginalis)

95054.m00081

Species: T.vaginalis
Alias: TvagK0568, 95054.m00081
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
95054.m00081.AA Protein None 336 None Fasta, JSON
95054.m00081.kin_dom Protein Kinase Domain None 250 None Fasta, JSON

Protein domain

Protein domains of 95054.m00081.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 95054.m00081.AA S_TKc 18-276 26 4.9e-74 253.19 SMART 1-231 (231) Show / Hide 
Range on Protein: 18-276
Range on HMM: 1-231/231
Sequence Identity: 26% (71 aa)

YKVLDILGYGGFAVVVLAQDINTQEKCAIKIIDRKEITKQNFLLYLENELRLSERFNHPNIVKVFEIIYEPDTIMIVMEYLSN--GDLQTLLEQNIN---
|..|...| |.|..| ......|....|||||.            ...|... .. .|||||| ...... | . .||||...  ||| ......     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FTIQEQFRIGLELLQAIKYLHDRGVCHRDIKPSNILFDDDFHPKIIDFGVSKEQSEALSTYCGTSFYMAPEIVKNKIYDGKKVDVWAFGITMNLITE
   |.  .  ..  ....|..|.|..|..|||.||.|||.|.  | ||.|||....     .|.||| .|||||..    |...|.|.|..|...     
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

KRFPWNKILNDAQFIKLVTQNKLEICVDQIGIIGDIISRCLVIDPNERASIDDLLKYIEEWQASRVF
 . |.    .... .|..         .. ..   .|..||. ||..| .. ..|.. ... .   |
GYPPFP---QMQMMFKKIG--------SPEAKD--FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 95054.m00081.AA Pkinase 18-267 26 1.6e-73 255.35 Pfam 1-293 (293) Show / Hide 
Range on Protein: 18-267
Range on HMM: 1-293/293
Sequence Identity: 26% (78 aa)

YKVLDILGYGGFAVVVLAQDINTQEKCAIKIIDRKEITK----QNFLLYLENELRLSERFNHPNIVKVFEIIYEPDTIMIVMEYLSNG----DLQTLLE-
|... ..| |.|..| ......|... |.|||..... .    ....|   .|...  |.||||||. ... ...| | .||||. .|    || .... 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL---SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-QNINF--TIQEQFRIGLELLQAIKYLHDRGVCHRDIKPSNILFDDDFHP----KIIDFGVS----KEQSEALSTYCGTSFYMAPEIVKNKIYDGKKVDV
 .. .|  . .|  .. ...|....|.|..|..|||.||.|||.|.. |.    ||.|||..       .. ..|.|||..|||||...   |.|.|||.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WAFGITMNLITEKRFPWNKI-----LNDAQFIKLVTQNKLEICVDQI---------------------GIIGDIISRCLVIDPNERASIDDLLKY--I
|..|...     .|.|.        ... | |... . .|.   ..                          |.|..||  ||..| .....|.   .
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 95054.m00081.AA CAMKL 18-265 29 2.5e-70 223.61 In-house 1-293 (297) Show / Hide 
Range on Protein: 18-265
Range on HMM: 1-293/297
Sequence Identity: 29% (87 aa)

YKVLDILGYGGFAVVVLAQD-INTQEKCAIKIIDRKEITKQNFLLY------------LENELRLSERFN---HPNIVKVFEIIYEPDT------IMIVM
|.... || |.|..| ||.. ..|.|| ||||||.| |..  . .             .. | .. ...|   ||||.| .|.|. |..      | .||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYLSNGD--LQTLLEQNIN----FTIQEQFRIGLELLQAIKYLHDRGVCHRDIKPSNILFDDDF--HPKIIDFGVSKE---Q----SEALSTYCGTSFYM
|| |.|.  |.  .... .    ..  |  |.   .. |..|.|..|..|||||| |||.|..     |||||| | .   .     . |.| ||.  ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIVKN--KIYDGKKVDVWAFGITMNLITEKRFPWNKI-----LNDAQFIKLVTQNKLEICVD---QIGIIGDIISRCLVIDPNERASIDDLLK
||||..   | |||.|||.|. |...  .   ..|..        .| .  ..  ....  . .   ..    |.|.. |. .|..|..|.....
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMN
Kinase 95054.m00081.AA CAMK 23-265 19 8e-66 210.82 In-house 1-421 (425) Show / Hide 
Range on Protein: 23-265
Range on HMM: 1-421/425
Sequence Identity: 19% (82 aa)

ILGYGGFAVVVLAQDINTQ------------EKCAIKIIDRKEITK------------------------QNFLLY-LENELRLSER-------FNHPNI
.|| |.|..| |....||.            .|.||||||.| ...                        . . .  ...|...  .        .||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKVFEIIY------------EPDT--------IMIVM---EYLSNG----DLQTLLEQN---------------INFTIQEQFRIGLELLQAIKYLHDRG
.| .|..               ..        . .||   || |.|    ||   . ..                 || .|  |.   ...|..|.|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VCHRDIKPSNILFDDD-----------------FHPKIIDFGVSKEQSE--------------------------ALSTYCGTSFYMA-PEIVKN-----
..|||.|| |||.||.                 .  |||||| ...  .                           ..|.|||  ||| ||...      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KIYDGKKVDVWAFGITMNLITEKRFPWNKIL------------NDAQFIKLVTQNKLEICVDQIGI------------------------IG
        | |.|.|.|.|. |. .      ..|..               || .  . ... | .   ... .                          
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DIISRCLVIDPNERASIDDLLK
| |...|. ||..|..|.. |.
DLIRKMLQVDPEKRMTIEQCLN
Kinase 95054.m00081.AA MARK 18-202 38 7.9e-60 194.31 In-house 1-194 (262) Show / Hide 
Range on Protein: 18-202
Range on HMM: 1-194/262
Sequence Identity: 38% (75 aa)

YKVLDILGYGGFAVVVLAQDINTQEKCAIKIIDRKEITK-QNFLLYLENELRLSERFNHPNIVKVFEIIY--EPDT-IMIVMEYLSNGDLQTLLEQNINF
||.|  .| |..|.| ||....|..| ||||.... ... |..   .. |...  . .||||.| |..|   .. . | ..||| |.|.|   ...  | 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKN-VMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

TIQEQ--FRIGLELLQAIKYLHDRGVCHRDIKPSNILFDDDF--HPKIIDFGVSKEQ--SEALSTYCGTSFYMAPEIVKNKIYDGKKVDVWAFGI
 ..|    ||   .. |..|.|.....|||||| ||| |..     |||||| | .    . |.| |||  ||||||.. | |||.|||.|. |.
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGV
Kinase 95054.m00081.AA Ciliate-E2 18-265 22 9.2e-59 200.33 In-house 1-361 (365) Show / Hide 
Range on Protein: 18-265
Range on HMM: 1-361/365
Sequence Identity: 22% (86 aa)

YKVLDILGYGGFAVVVLAQDINTQE------------------KCAIKIIDRKEITKQNFLLYLENELRLS----------------ERFNHPNIVKVFE
||.. ..| |.|..| .......|.                  |..|||.  | . |.. . ....|...                 |. |||||.| .|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQ-IEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

IIY--EPDTIMIVMEYLSNGDLQTLLEQNI-----------NFTIQEQFRIGLELLQ---------------AIKYLHDRG-VCHRDIKPSNILFDDDFH
  .    ..| .||||.. |||. ....|            .||..|  .|  ..||               |..||| .. ..||||||.||||     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

PKIIDFGVSKEQS----------------------------------EALSTYCGTSFYMAPEIVKNKIYDG--------KKVDVWAFGITMNLITEKRF
.|||||| ||...                                  .   |.|||  ||||||...| ||.        .|.|.|..|...     ...
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PWNKILNDAQFIKLVTQNKLEICVDQIGIIG-----------------------DIISR----CLVIDPNERAS-IDDLLK
|.              |.. . |  ..                           |.|..    .|. ||..| . ....|.
PF--------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 95054.m00081.AA ULK 18-265 24 1.6e-56 194.14 In-house 1-325 (329) Show / Hide 
Range on Protein: 18-265
Range on HMM: 1-325/329
Sequence Identity: 24% (80 aa)

YKVLDILGYGGFAVVVLAQDINT----QEKCAIKIIDRKEITKQNFLLY-------LENELRLSERFN--------HPNIVKVFEIIYEP--DTIMIVME
| . ..|| | |..|  . ...|    .||.|.|.||.... ..| . .       |.|| ..  . .        |||||| ... ...  . | |.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YLSNGDLQTLLEQN----------INFTIQEQFRIGLELLQAIKYLHDRGVCHRDIKPSNILFDDDF------------HPKIIDFGVSKE-QSE-----
|   |||......|           ... ||   .   .|.. |.||.... ||||||.||| ....            . || ||| .|  ...     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

ALSTYC------GTSFYMAPEIVK----NKIYDGKKVDVWAFGITMNLITEKRFP---WNKILNDAQFIKLVTQ-NKLE--ICVDQIGIIG---------
 . |.       ||  ||||.|..    .| |. .|.|.| .|. .  .   . |   |.  ... . .||. . ....  |.  .. .           
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

---DIISRCLVIDPNERASIDDLLK
   |.|.|.|..|...| |...|..
ECKDLIRRMLQYDEKDRISWEELFN
Kinase 95054.m00081.AA ULK 18-265 23 2.8e-55 189.98 In-house 1-320 (324) Show / Hide 
Range on Protein: 18-265
Range on HMM: 1-320/324
Sequence Identity: 23% (77 aa)

YKVLDILGYGGFA-VVVLAQDINT---QEKCAIKIIDRKEITKQNFL-------LYLENELRLSERFN---HPN--IVKVFEIIYEP--DTIMIVMEYLS
| . ..|| | |. .|  . ...|   ... |.|.||.|.. |.. .         |.|| ..   ..   |||  ||| ... ...  . | |.|||  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGDLQTLLEQN---------INFTIQEQFRIGLELLQAIKYLHDRGVCHRDIKPSNILFDDDF------------HPKIIDFGVSKE-QS-----EALST
 |||......|          ... ||   .   .... |.||.... ||||||.|||  ...            . || ||| .|  ..       . |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

YC------GTSFYMAPEIVK----NKIYDGKKVDVWAFGITMNLITEKRFP---WNKILNDAQFIKLVTQ----------NKLEICV--DQIGI---IGD
..      ||  ||||.|..    .| |. .|.|.| .|. .  .   . |   |.  ...   .||. .          .....    ... |   . |
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

IISRCLVIDPNERASIDDLLK
.|.|.|..|...| |......
LIRRMLQYDEKDRISWEEIFN
Kinase 95054.m00081.AA TKL 24-267 19 1.8e-49 170.64 In-house 1-364 (364) Show / Hide 
Range on Protein: 24-267
Range on HMM: 1-364/364
Sequence Identity: 19% (72 aa)

LGYGGFAVVVLAQDINTQ--------EKCAIKIIDRKEITKQN------------------------FLLYLENELRLSERFNHPNIVKVFEIIYEPDT-
.| |||..|  ..  ..         .  |.|.. ...  . .                        |   .|.|...  |..|||||.   .  .|.  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------IMIVMEYLSNGD-LQTLLEQNINFTIQEQFRIGLELLQAIKYLHD--------RGVCHRDIKPSNILFDDDFH--------------P
            ..||||| ..|. | .|.       ..  .|. |.  ... |||         ... |||.|..||| |....              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KIIDFGVSKEQSE----------------------ALSTYCGTSFYMAPEIVKNKIYDGKKV---------------DVWAFGITM-NLITEKRFPWNKI
|| ||| |.. |.                      ...| |||  .||||. ...... .||               ||..||| .  ..| .| |. ..
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-PYYDY

LND--------AQFIKLVTQNKLEICVD-----------QIGI---IGDIISRCLVIDPNERASIDDLLKYI
 ..         .....| ...|   ..              .   . ... .|   ||..| | ...||..
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 95054.m00081.AA STE 18-204 21 3.1e-49 169.88 In-house 1-258 (359) Show / Hide 
Range on Protein: 18-204
Range on HMM: 1-258/359
Sequence Identity: 21% (58 aa)

YKVLDILGYGGFAVVVLAQDIN---------------TQEKCAIKIIDRKEITK--------------QNFLLYLENELRLSERFN--HPNIVKVFEIIY
.. ....| |.| .|..| ...               |.| .|||... .. ..              .. .  ...|...  ..|  |||||| .   .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EP-------DTIMIVMEYLSNGDLQTLLE------QNIN------FTIQEQFR--IGLELLQA-IKYLHDRGVCHRDIKPSNILFDDDFHPKIIDFGVSK
         |.. |.|||...| |  ...      .. |      ....|.    |  ..|..  .|||. .. ||||||.|||.      |..||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

EQSEALS-------------------TYCGTSFYMAPEIVKN-----KIYDGKKVDVWAFGITM
  .. ..                   | .||  .||||....     .   . |.|.| .|.|.
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTI
Kinase 95054.m00081.AA Ciliate-E2-Unclassified 18-265 21 5.9e-49 167.94 In-house 1-348 (352) Show / Hide 
Range on Protein: 18-265
Range on HMM: 1-348/352
Sequence Identity: 21% (75 aa)

YKVLDILGYGGFAVVVLAQDINTQEKC-----AIKIIDRK-EITKQNFLLYLENELRLSERF----------------NHPNIVKVFEIIYE--PDTIMI
||.. ..| |||..| ..|..... .      ..||...|  . ...   .. ..... ..                 |||....| .. ..   ..| |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEYLSNGDLQTLLEQNIN-----------------FTIQEQF-----RIGLELLQAIKYLHDRG-VCHRDIKPSNILFDDD---FHPKIIDFGVSKE--
||||. .|||.  .... .                 || |.       ..  ..||...|||  . ..||||||.|||||..   ...|||||| ||.  
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----------------QSEALSTYCGTSFYM----APEIVKNKIYDG---KKVDVWAFGITMNLITEKRFPWNKILNDA---------------QFIKLV
                ... ..| |||  ||    |||. ... ||.   .|.|.|..|. .  .   ..| .    .                |...  
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

TQNKLEICV-------DQIGIIG-----DIISRCLVIDPNERASIDDLLK
 |.....         ...   .     |.....|. .||.| .....|.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN
Kinase 95054.m00081.AA CAMK1 124-202 38 8.3e-31 86.74 In-house 116-204 (276) Show / Hide 
Range on Protein: 124-202
Range on HMM: 116-204/276
Sequence Identity: 38% (35 aa)

ELLQAIKYLHDRGVCHRDIKPSNILFDDD-FHP--K--IIDFGVSKEQS-E--ALSTYCGTSFYMAPEIVKN---KIYDGKKVDVWAFGI
..|.|..|.|..|..|||.|| |.|. |  ..   |  |.||| ||  . .   ..| |||  |.|||....   | || |..|.|  |.
QILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYD-KACDMWSIGV
Kinase 95054.m00081.AA CAMK1 18-103 31 4.7e-26 72.69 In-house 1-95 (276) Show / Hide 
Range on Protein: 18-103
Range on HMM: 1-95/276
Sequence Identity: 31% (30 aa)

YKVLDILGYGGFAVVVLAQDINT---QEKCAIKIID-RKEITK---QNFLLYLENELRLSERF---NHPNIVKVFEIIYEPDTIMIVMEYLSNGDL
|.. ...| | |..|.|.....|   ... |||.|| .| . |   |  . .||||.    ..   .||||.| .|.  ... . .|||....|.|
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQK-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGEL
Kinase 95054.m00081.AA TyrKc 18-267 21 6.7e-21 76.68 SMART 1-280 (280) Show / Hide 
Range on Protein: 18-267
Range on HMM: 1-280/280
Sequence Identity: 21% (61 aa)

YKVLDILGYGGFAVVVLAQDINTQEKCAIKIIDRKEITKQNFLLYLENELRLSERF--NHPNIVKVFEIIYEP-------DTIMIVMEYLSNGDLQTLLE
 . ...|| | | .|.... .   ...|.| .          .  . .|.|.  ..  .|||||. . .. ..       . .|||||| ..|||.  | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QNIN-FTIQEQFRIGLELLQAIKYLHDRGVCHRDIKPSNILFDDDFHPKIIDFGVSKEQSEA------LSTYC-----GTS-----FYMAPEIVKNKIYD
 . . .. ..   . .   .   |||.... |||.   |.| ..... || ||| |..  .        ..|      |.        ||||  . ... 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GKKVDVWAFGITMN-LITEKRFPWNKI----LNDAQFIKLVTQNKLEICVDQ---------IGIIGDIISRCLVIDPNERASIDDLLKYI
  | |||.||..|  . |    |.  .    ..... |..| | .   . .             . .|...|   ||..| .  .. ...
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 95054.m00081.AA Pkinase_Tyr 18-204 24 2.8e-14 48.99 Pfam 1-204 (270) Show / Hide 
Range on Protein: 18-204
Range on HMM: 1-204/270
Sequence Identity: 24% (50 aa)

YKVLDILGYGGFAVVVLAQDI----NTQEKCAIKIIDRKEITKQN-FLLYLENELRLSERF-NHPNIVKVFEIIY-EPDT--IMIVMEYLSNGDLQTLLE
 . .  || | | .|...       ||. ..|.|.. .   .... ..  . .|...   . .|||||.   ... . .   |.|||||  .||| . | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

Q----NINFTIQEQFRIGLELLQAIKYLHDRGVCHRDIKPSNILFDDDFHPKIIDFGVSKEQSEALSTY-CGTS------FYMAPEIVKNKIYDGKKVDV
.    . ..|...   . ..  ..  ||....  |||.   |.| ..... || ||| ..   .  ..|   ..      . ||||  .....   | ||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFT-TKSDV

WAFGITM
|.||..|
WSFGVLM
Kinase 95054.m00081.AA STE 244-267 42 3e-06 18.37 In-house 332-359 (359) Show / Hide 
Range on Protein: 244-267
Range on HMM: 332-359/359
Sequence Identity: 42% (12 aa)

DIISRCLVIDPNERASIDDLLK----YI
| |..||..|||.|.. ..|||     |
DFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 95054.m00081.AA APH 124-161 23 0.000226 15.79 Pfam 162-200 (248) Show / Hide 
Range on Protein: 124-161
Range on HMM: 162-200/248
Sequence Identity: 23% (10 aa)

ELLQAIKYLHDRGVCHRDIKPSNILFD--DDFHPK--IIDFG
.|...     ....||.| .| |...|  .|  .   .||..
WLEAHWP---PPCWCHGDFHPGNVMWDPRPDGGRVTGVIDWD
Kinase 95054.m00081.AA MARK 244-265 36 0.001988 7.26 In-house 237-258 (262) Show / Hide 
Range on Protein: 244-265
Range on HMM: 237-258/262
Sequence Identity: 36% (8 aa)

DIISRCLVIDPNERASIDDLLK
..|.| |...|.||..|....|
NLIQRLLTVNPEERPTIEEIMK