Gene 89419.m00139 (T.vaginalis)

89419.m00139

Species: T.vaginalis
Alias: 89419.m00139, TvagK0077
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: AMPK

Sequence

Name Sequence Type Origin Length Description Download
89419.m00139.AA Protein None 392 None Fasta, JSON
89419.m00139.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of 89419.m00139.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 89419.m00139.AA AGC 19-274 23 1.8e-103 267.81 In-house 1-395 (395) Show / Hide 
Range on Protein: 19-274
Range on HMM: 1-395/395
Sequence Identity: 23% (95 aa)

YKLIREIGVGSFSIVWLARNL------KADLDVAIKIIPKKR---IAT--DVNIIR----------FERETNFLKQLD----------HPLIAQ-YFEHL
..... || |||. |.|.|          .   |.|.. ||.   |    .|  .           . .| | |....          || | .  .   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EDDNY--HYFVMELAP---------NG-DLLAAVN---RQGKMDEQQAKLYFAQ-------LIVVLDYLHNDMLVAHRD-LKAENVLLDKNENIRLIDFG
.|...   |||||..|          | .|.       ..|..||..|. |.|.       ..  |.|||. | . ||| || ||.|||.. .|.| |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FSRSFTADD--------------------------------------------------PNLNTTCG--SPAYVPPEMIKREAYTVQADVWS--TGILLY
..  .  |.                                                     .| ||  .| |..||..    |. ..| ||   |.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

SLVVGRLPFEDSENN--------VQKILQKIA------YSEPFYP----------RFISPDLKDLLTKMLTKQPDKRIT----------IAEIRKHPWF
 ...|. || . ...          .. |||         .. .|          |..||..|||..|.|.| |.||..          . ||..||||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 89419.m00139.AA CAMKL 19-274 33 2.2e-99 317.83 In-house 1-297 (297) Show / Hide 
Range on Protein: 19-274
Range on HMM: 1-297/297
Sequence Identity: 33% (102 aa)

YKLIREIGVGSFSIVWLARN-LKADLDVAIKIIPKKRIATDVNIIRF------------ERETNFLKQLD---HPLIAQYFEHLEDDNY------HYFVM
|......| |||. | ||.. .     |||||| ||.|  | .. .             .|| . .|.|.   || | . .|..|....       | ||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELAPNGD--LLAAVNRQ----GKMDEQQAKLYFAQLIVVLDYLHNDMLVAHRDLKAENVLLDKNE--NIRLIDFGFSRSFTA----DDPNLNTTCGSPAY
|....|.  |.  . ..    |.|.| .|. || |..  ..|.|. . ..|||.|.||.|||.|   || .||||||  ..     ..  |.| ||||.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

VPPEMIKR--EAYT-VQADVWSTGILLYSLVVGRLPFEDSENN-----VQKILQKIAYSEPFYPR---FISPDLKDLLTKMLTKQPDKRITIAEIRKHPW
 .||....  . |   ..|.|| |..|| .|.|.|||.|  .|      .  | ..  .  .||.   ..| |..||. |||.. |.||.|| .|..|||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

F
.
M
Kinase 89419.m00139.AA CAMK 24-274 23 2.3e-99 320.85 In-house 1-425 (425) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-425/425
Sequence Identity: 23% (99 aa)

EIGVGSFSIVWLARNLKAD------------LDVAIKIIPKKRIA-------------------------TDVNIIRFERETNFLKQ-------LDHPLI
..| |||..| |... .                ||||||.||..                          ....  ...|| . .|.       |||| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

AQYFEHLED-------------------DNYHYFVM---ELAPNG----DLLAAVNRQ---------------GKMDEQQAKLYFAQLIVVLDYLHNDML
 . .|. ||                   |.. |.||   |....|    ||.  . ..               |...|..|. || |..  ..|.|.   
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-

VAHRDLKAENVLLDKNE-----------------NIRLIDFGFSRSFTA-----------------------DDPNLNTTCGSPAYVP-PEMIKR-----
..||||| ||.|||.|.                 || .|||||.. |.                        ... ..| ||.|.|.. ||....     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------EAYTVQADVWSTGILLYSLVVGRLPFEDS-----------ENNVQKILQKIA---YS-EPFY---------------------PRFISPDL
         . |. ..|.|| |..|| ...|..||...            .| .....||    |. .|.|                     . |.|.. 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQEC

KDLLTKMLTKQPDKRITIAEIRKHPWF
|||. |||.. |.||.||... .|||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
S_TKc 89419.m00139.AA S_TKc 19-274 32 7.2e-96 325.72 SMART 1-231 (231) Show / Hide 
Range on Protein: 19-274
Range on HMM: 1-231/231
Sequence Identity: 32% (89 aa)

YKLIREIGVGSFSIVWLARNLKADLDVAIKIIPKKRIATDVNIIRFERETNFLKQLDHPLIAQYFEHLEDDNYHYFVMELAPN--GDLLAAVNRQGK---
|...|.|| |.|. |...|. | .  ||||||.          ....|| . ||. .|| | ..... .| .. |.|||....  |||.    ..|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---MDEQQAKLYFAQLIVVLDYLHNDMLVAHRDLKAENVLLDKNENIRLIDFGFSRSFTADDPNLNTTCGSPAYVPPEMIKREAYTV-QADVWSTGILLY
   ..| .|. |..|..  |.|.|.   . ||||| ||.|||.  .| ..|||..| .       .| ||.| |..||..    |.   .|.|| |..||
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

SLVVGRLPFEDSENNVQKILQKIAYSEPFYPRFISPDLKDLLTKMLTKQPDKRITIAEIRK-------HPWF
 ...|. ||.    ..|....||           ||..||.. |.|.| |.||.|. |. .       ||||
EMLCGYPPFP----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 89419.m00139.AA AMPK 19-274 39 7.1e-90 267.0 In-house 1-254 (254) Show / Hide 
Range on Protein: 19-274
Range on HMM: 1-254/254
Sequence Identity: 39% (103 aa)

YKLIREIGVGSFSIVWLARNLKADLDVAIKIIPKKRIATDVNIIRFERETNFLKQLDHPLIAQYFEHL-EDDNYHYFVMELAPNGDLLAAVNRQGKMDEQ
| .   ||.|.|  | ..       .|||||. |..|. .    | .||   || . || | | .| . |     . ||| ...|.|   . . |...|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

QAKLYFAQLIVVLDYLHNDMLVAHRDLKAENVLLDKNENIRLIDFGFSRSFTADDPNLNTTCGSPAYVPPEMIKREAYT-VQADVWSTGILLYSLVVGRL
.|. .|.| |  ..|.|. | ..||||| ||.|||.| || . ||| |   .     | | |||| |  ||||    |   . |.||.|. || .. |.|
EACRFFQQIISGVEYCHRHM-IVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDG-EFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYL

PFEDSENNVQKILQKIAYSEPFYPRFISPDLKDLLTKMLTKQPDKRITIAEIRKHPWF
||.|.  |. .  .||   |.  |.|.||. |||. .||.. | ||||| .||.||||
PFDDE--NTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 89419.m00139.AA Pkinase 19-274 29 5e-84 290.27 Pfam 1-293 (293) Show / Hide 
Range on Protein: 19-274
Range on HMM: 1-293/293
Sequence Identity: 29% (87 aa)

YKLIREIGVGSFSIVWLARNLKADLDVAIKIIPKKRIATDVNIIRFE-RETNFLKQLDHPLIAQYFEHLEDDNYHYFVMELAPNG----DLLAAVN--RQ
|...| || |||. |..... .    ||.|||.|...  .......  .|   .| |.|| | ....  ||... |.|||....|    || . .   |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKM--DEQQAKLYFAQLIVVLDYLHNDMLVAHRDLKAENVLLDKNENI----RLIDFGFSRSF-TADDPNLNTTCGSPAYVPPEMIK-REAYTVQADVWS
|..  .|...| |. |..  |.|.|. | . ||||| ||.|.|.| .|    ...|||... | .  .. ..| ||.| |..|| |. .. |.  .|.||
GCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

TGILLYSLVVGRLPFEDS----ENNVQKILQKIAYSEPFYPRFIS---------------------PDLKDLLTKMLTKQPDKRITIAEIRKHPWF
 |..|| .. ||.|| ..    ... ......| . .. .... .                     ...||.....|.| | ||.|...| .||||
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 89419.m00139.AA MARK 19-274 35 9.1e-84 273.7 In-house 1-262 (262) Show / Hide 
Range on Protein: 19-274
Range on HMM: 1-262/262
Sequence Identity: 35% (94 aa)

YKLIREIGVGSFSIVWLARNLKADLDVAIKIIPKKRIATDVNIIRFERETNFLKQLDHPLIAQYFEHLE-DDNYH--YFVMELAPNGDLLAAVNRQ--GK
||....|| ||.. | ||.... .  |||||..|...    ..  ..|| . .|.|||| | ..|.  | |.. |  |..||.|..|.|.  .  .  |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

MDEQQAKLYFAQLIVVLDYLHNDMLVAHRDLKAENVLLDKNE--NIRLIDFGFSRSFTADDPNLNTTCGSPAYVPPEMIKREAYT-VQADVWSTGILLYS
. |  |. .| |..  . |.|. . ..|||.|.||.|.|.|   || .||||||. ..  .  ||| ||.|.| .||..... |.   .|.|| |..|| 
LHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPP-GQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYF

LVVGRLPFEDSENNVQKILQKIAYSEPFYPRFISPDLKDLLTKMLTKQPDKRITIAEIRKHPWF
.|.|..||... ..  .. .||   .. .| ..|.....|. ..||  |..|.|| || ||||.
MVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 89419.m00139.AA QIK 19-274 36 1.3e-78 267.45 In-house 1-272 (272) Show / Hide 
Range on Protein: 19-274
Range on HMM: 1-272/272
Sequence Identity: 36% (100 aa)

YKLIREIGVGSFSIVWLARNLKADLDVAIKIIPKKRIATDVNIIRFERETNFLKQLDHPLIAQYFEHLEDDNYHYFVMELAPNGDLLAAVNRQGK-----
| . | || | | .| |||.  .   |||||| | .. .  |... .||   .|.|.|| |   .. .| |.. | |.| ..||..  ... .|.     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQL-DEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------MDEQQAKLYFAQLIVVLDYLHNDMLVAHRDLKAENVLLDKNENIRLIDFGFSRSFTADDPNLNTTCGSPAYVPPEMIKREAYT-V
               | |..|.  | |..   .|.|.   | ||||||||.|||.| || ..|||||  |. . . |.| ||||.|  ||| . . |.  
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIV-HRDLKAENILLDNNMNIKIADFGFSNWFKQGQL-LMTWCGSPPYAAPEMFEGKEYDGP

QADVWSTGILLYSLVVGRLPFEDSENNVQKILQKIAYSEPFYPRFISPDLKDLLTKMLTKQPDKRITIAEIRKHPWF
..|.|| |..||.|| | |||  .  ..|.  |..       | |.| |. .|  .||.  |..|.||. |..|.| 
KVDIWSMGVVLYVLVCGALPFDGK--TLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 89419.m00139.AA Ciliate-E2-Unclassified 19-274 28 3e-78 266.29 In-house 1-352 (352) Show / Hide 
Range on Protein: 19-274
Range on HMM: 1-352/352
Sequence Identity: 28% (100 aa)

YKLIREIGVGSFSIVWLARNLKADLDVAIKIIPKKRIAT-------DVNIIRFERETN----------------FLKQLDHPLIAQYFEHLEDDNYHYFV
||.|. || |.|..|..... | ..  |.|.. |..|         | .|.. . | |                 |....||.|  .|.. .|... |.|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MELAPNGDLLAAVNRQGK-----------------MDEQQAK-----LYFAQLIVVLDYLHNDMLVAHRDLKAENVLLDKNE---NIRLIDFGFSRSFTA
||....|||.   . ..|                  .|||||      ||||... |.|||    . |||.| ||.|.|.|    .|..||||.|.    
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

D---------------DPNLNTTCGSPAYV----PPEMIKREAYT----VQADVWSTGILLYSLVVGRLPFEDSENNV------------------QKIL
.               . ...|.||.| |     .||..... |      ..|.|| |..|| .. |..||.|   .                   |.|.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

QKIAYSEPFYP----RFISPDLKDLLT----KMLTKQPDKRITIAEIRKHPWF
||. .  .| .      .||  ||...    ||| |.|.||||. .| .||||
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 89419.m00139.AA Ciliate-E2 19-274 26 6.3e-78 265.2 In-house 1-365 (365) Show / Hide 
Range on Protein: 19-274
Range on HMM: 1-365/365
Sequence Identity: 26% (99 aa)

YKLIREIGVGSFSIVWLARNLKAD-----------------------LDVAIKIIPKKRIATDVNIIRFERETN----------FLKQLDHPLIAQYFEH
||.|. || |.|..|..... | .                         .|.||. |. |    ..|.  || |           |.||.|| | ...|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LE--DDNYHYFVMELAPNGDLLAAVNRQ-----------GKMDEQQAKLYFAQLIV---------------VLDYLHNDMLVAHRDLKAENVLLDKNENI
 .  |||. |.|||..  |||.   . .           ....|...| ...|..                 | |||.   . |||.| ||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RLIDFGFSRSFTADDPN-------------------------------LNTTCGSPAYVPPEMIKREA---------YTVQADVWSTGILLYSLVVGRLP
 .||||.|. .. |  |                                ||.||.| |..||.....          |. ..|.|| |..|| .. |..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FEDSENNVQKILQ-KIAYSEPFYP-----------RF--ISPDLKDLLTK----MLTKQPDKRIT-IAEIRKHPWF
|       |.|.| || ...|..             .  .|.. |||. |    || |.|.|||| . .| .||||
F------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 89419.m00139.AA RSK 19-274 27 2.8e-69 236.48 In-house 1-278 (278) Show / Hide 
Range on Protein: 19-274
Range on HMM: 1-278/278
Sequence Identity: 27% (78 aa)

YKLIREIGVGSFSIVWLARNLKADLDVAIKIIPK-KRIATDVNIIRFERETNFLKQLD-HPLIAQYFEHLEDDNYHYFVMELAPNGDLLAAVNRQGK---
 |.  ..|.|.....   .. ...   | |.. | |...... . .  .| | |.    || | ....  ... . | .||. . |.|.    ...    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

MDEQQAKLYFAQLIVVLDYLHNDMLVAHRDLKAENVLLDK---NENIRLIDFGFSRSFTAD-DPNLNTTCGSPAYVPPEMIK----REAYTVQADVWSTG
..|  |. |.|.... ...||    . ||||| ||.|.|    .. |.|.||||.. | .|    ..| |.. .|..|||.|    ..... ..|.|| |
FSEDEACFYMAEIVLAVEHLHQQG-IIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

ILLYSLVVGRLPFED-SENNVQKILQKIAYSE--PFYP--RFISPDLKDLLTKMLTKQPDKRIT-----IAEIRKHPWF
.|.| . .|..||     || ..|...|   .  .  |   ..|.. |||..|||.. | ||..     ..||..||||
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 89419.m00139.AA AktR 19-274 32 1.9e-68 233.71 In-house 1-268 (268) Show / Hide 
Range on Protein: 19-274
Range on HMM: 1-268/268
Sequence Identity: 32% (89 aa)

YKLIREIGVGSFSIVWLARNL-KADLDVAIKIIPKKRIATDVNIIRFERETNFLK-QLDHPLIAQYFEHLEDDNYHYFVMELAPNGDLLAAVNRQGKMDE
..... .| | |. | |.. . . .  .|.|.| || |     . .  .| | .. . .|| | . ..  ..... .|.||  |.|.|.   ....|..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

QQAKLYFAQLIVVLDYLHNDMLVAHRDLKAENVLLDKNENIRLIDFGFSR-SFTA-DDPNLNTTCGSPAYVPPEMIKR-EAYTVQADVWSTGILLYSLVV
.||. |||| .  |.|||. |..  |||| || |||.. .....||| |.  |   .|.  .. ||.|.|..||||.. . .. ..| |. ||..| .|.
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GRLPFEDSENNVQKILQKIAYSE---PFYPRFISPDLKDLLT-KMLTKQPDKRIT-----IAEIRKHPWF
|  ||..  .| . ..||| ...   . ||  .|. .|||.. | | | | ||..     . ||..||||
GCPPFYH--KNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 89419.m00139.AA TyrKc 19-274 21 6.5e-15 18.41 SMART 1-280 (280) Show / Hide 
Range on Protein: 19-274
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YKLIREIGVGSFSIVWLARNLKADLDVAIKIIPKKRIATDVNIIRFERETNFLKQL--DHPLIAQYFEHLEDD-------NYHYFVMELAPNGDLLAAV-
 .|....| | | .|....     ..||.| . .        .  | || . ...|  .|| | . .    ..         .. |||..|.|||.    
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NRQGKMDEQQAKLYFAQLIVVLDYLHNDMLVAHRDLKAENVLLDKNENIRLIDFGFSRSFTADDPN----LNTTC----GSP-----AYVPPEMIKREAY
....|   ..   .  |     .|||   .. |||| | |.|...|  ..  ||| ||  . || .       .     |.         .|| |.   .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCI-HRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TVQADVWSTGILLY---SLVVGRLPFED-SE--NNVQKILQKIAYS--EPFYPRF-------ISPDLKDLLTKMLTKQPDKRITIAEIRKHPWF
| . |||| |....   ..  |  | ..  .   . | .....      |  |          .... .. ..    .|..| | .||  |  |
TTKSDVWSFGVCMWEIFTY--GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 89419.m00139.AA Pkinase_Tyr 19-105 27 4.3e-11 38.19 Pfam 1-95 (270) Show / Hide 
Range on Protein: 19-105
Range on HMM: 1-95/270
Sequence Identity: 27% (27 aa)

YKLIREIGVGSFSIVWLARNL----KADLDVAIKIIPKKRIATDVN--IIRFERETNFLKQL-DHPLIAQYFEHLE-DDNY--HYFVMELAPNGDLL
 ......| |.|  |....      . ...||.|..  |  |.. .  .  | || . .||| .|| | ..      ..    .| |||..|.||||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL
Kinase 89419.m00139.AA Pkinase_Tyr 141-209 31 0.001316 12.84 Pfam 134-205 (270) Show / Hide 
Range on Protein: 141-209
Range on HMM: 134-205/270
Sequence Identity: 31% (23 aa)

HRDLKAENVLLDKNENIRLIDFGFSRSFTADDPNL-NTTC---GSPAYVPPEMIKREAYTVQADVWSTGILLY
|||| | |.|...|  ..  ||| .|    .| .   ..          .|| |.   .|.. |||| |.|..
HRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMW