Gene 93088.m00125 (T.vaginalis)

93088.m00125

Species: T.vaginalis
Alias: TvagK0105, 93088.m00125
External Links:
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: Fused

Sequence

Name Sequence Type Origin Length Description Download
93088.m00125.AA Protein None 965 None Fasta, JSON
93088.m00125.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 93088.m00125.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93088.m00125.AA Fused 4-254 49 7.4e-119 401.17 In-house 1-251 (251) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-251/251
Sequence Identity: 49% (125 aa)

YKLIQQIGEGSFGRVFKARRKYTGRMVAIKTIQKGNMKDEDLVNFRREVDILKKVDHPNIMRLLEYFETDSEFCLVTELGRGDLFQIISDTQRLPEEQLK
|   . .|.||||.|.||||||  . |||| | |    |  | | |||..| ..  ||.|  ... |||| |   ||.   ..|.|. ..   .|||| .
YHVSEMVGQGSFGCVYKARRKYDSKVVAIKFIPKRGRSDKELKNLRRECEIMRRMHHPHIIHMIDSFETDKEVVVVTDYAEMELHQYLEYDGKMPEEQVR

PIAAQLVSALNHLHQKKIIHRDLKPQNILVSDNSSIKLCDFGFARALSRTTLVLNSIKGTPLYMAPELVQEYPYTEKIDIWSLGIILYELYYGKPPYFTD
 ||..|||||  ||   | |||.||||||   |  ||||||||||..|  |.|| |||||||||||||| | ||    |.|||| |||||  |.||... 
RIACHLVSALYYLHSHRILHRDMKPQNILLDKNMHIKLCDFGFARNMSINTHVLTSIKGTPLYMAPELVEEQPYDHHADMWSLGCILYELMVGQPPFCAN

SMYNLIKMIINEPITWPGPISDEFKDFILKALVKDPDSRWSCEQLLNHPWI
| . |..||. ... ||  |. ... |    | |||  | |  ||| || .
SIFHLVSMIKHDDVKWPSTITSCCRNFLQGLLTKDPRHRISWPQLLCHPFV
Kinase 93088.m00125.AA S_TKc 4-254 39 3.2e-113 383.38 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-231/231
Sequence Identity: 39% (105 aa)

YKLIQQIGEGSFGRVFKARRKYTGRMVAIKTIQKGNMKDEDLVNFRREVDILKKVDHPNIMRLLEYFETDSEFCLVTELGRG---DLFQIISDTQR----
|.....||.|.||.|.|.| | ||| |||| |           ..|||..|||| .|||| .|...|.. .....|.|.  |   |||..| . .|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LPEEQLKPIAAQLVSALNHLHQKKIIHRDLKPQNILVSDNSSIKLCDFGFARALSRTTLVLNSIKGTPLYMAPELVQEYPYTE-KIDIWSLGIILYEL
  .|| . . ...|...||...|...||||||||.|||...   ||.||||.|| |       ... ||| |||||..   .|.  |.|.||.|.||||.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

YYGKPPYFTDSMYNLIKMIINEPITWPGPISDEFKDFILKALVKDPDSRWSCEQLLN-------HPWI
..|.||.    |. ..|.|           |.|.|||| | |.|||. |... ..|.       |||.
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 93088.m00125.AA AGC 4-254 25 1.2e-110 286.76 In-house 1-395 (395) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-395/395
Sequence Identity: 25% (100 aa)

YKLIQQIGEGSFGRVFKARRK------YTGRMVAIKTIQKGN--------MKDEDLVN--------FRREVDILKKVD----------HPNIMR-LLEYF
....  ||.||||.|. .|.|       ||.. |.| ..|          | .  ..         ...| .||.|..          ||.| . |   |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ETDSE--FCLVTEL----------GRG-DLFQIIS---DTQRLPEEQLKPIAAQ-------LVSALNHLHQ-KKIIHRD-LKPQNILVSDNSSIKLCDFG
....    ..| |.          | | .||...    . .|..||. . .||.       .|.|| .||. ..||||| ||| |||  ..  |||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FARALSR--------------------------------------------------TTLVLNSIKG--TPLYMAPELVQEYPYTEKIDIWS--LGIILY
..  . .                                                   .   ... |  || ||||| .    |.   |.||  ||...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELYYGKPPYFTD-------------SMYNLIK---MIINEPITWPGP----------ISDEFKDFILKALVKDPDSRWSC----------EQLLNHPWI
|. .|.||.. |              |...|.   ..||.....| |          .|.| ||.| | |.|||. |  |          |.. |||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 93088.m00125.AA Pkinase 4-254 35 4.4e-107 366.85 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-293/293
Sequence Identity: 35% (104 aa)

YKLIQQIGEGSFGRVFKARRKYTGRMVAIKTIQKGNMKDEDLVNFRR--EVDILKKVDHPNIMRLLEYFETDSEFCLVTELGRG-----DLFQIIS--DT
|.....||.||||.|.|...| ||..||.|.| | . |.. ... ||  |. |.|...|||| ||...||.... ..|.|. .|     ||| .||  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

QRL--PEEQLKPIAAQLVSALNHLHQKKIIHRDLKPQNILVSDNSSI----KLCDFGFARAL-SRTTLVLNSIKGTPLYMAPELVQ-EYPYTEKIDIWSL
 ..  .|...| .. |....|...|...||||||||.|||...|  |    |.||||.|. .       .... ||| |||||...   .|. |.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIILYELYYGKPPYFTD------SMYNLIKMIINEPITWPGPIS---------------------DEFKDFILKALVKDPDSRWSCEQLLNHPWI
|.||||.. |.||.  .      ... .|..|   |. .. | .                     .|.|||| . | ||| .|...||.|.|||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 93088.m00125.AA CAMK 9-254 25 4.5e-102 329.74 In-house 1-425 (425) Show / Hide 
Range on Protein: 9-254
Range on HMM: 1-425/425
Sequence Identity: 25% (109 aa)

QIGEGSFGRVFKARRKYTG------------RMVAIKTIQKGNMK--------------------------DEDLVNFRREVDILKK-------VDHPNI
..|.|||| |.....| |.            . |||| | |  .|                          ..|. |.|||..|.||       .|||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

MRLLEYFET-------------------DSEFCLVT---ELGRG-----DLFQIISDT---------------QRLPEEQLKPIAAQLVSALNHLHQKKI
 .|.|..|.                   |.....|.   |.  |     |||. | .                 |..|.. . .  |..||....|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKPQNILVSDNS-----------------SIKLCDFGFARALSR-----------------------TTLVLNSIKGTPLYMA-PELVQ-------
.|||||| |||..||.                  ||..|||||. . .                       ..  ..   ||| ||| ||...       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------EYPYTEKIDIWSLGIILYELYYGKPPYFTD-------------SMYNLIKMIINEPITWPGP----------------ISDE--------FKD
       . .|..|.|.||.|.||| .  |.||.  |             ..|.| ..|..   ..| |                ||||         ||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FILKALVKDPDSRWSCEQLLNHPWI
.| | |..||. |...|| |||||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 93088.m00125.AA ULK 4-254 33 1.8e-95 323.47 In-house 1-324 (324) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-324/324
Sequence Identity: 33% (108 aa)

YKLIQQIGEGSFG-RVFKARRKYT---GRMVAIKTIQKGNMKDEDLV--------NFRREVDILKKVD---HPN--IMRLLEYFETD--SEFCLVTELGR
| |....|.||||  |.|.| | |   .  ||.| |.| .|..  .         ....|. |.|| .   |||  | .|...|||.    .....|.  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

G-DLFQIIS---------DTQRLPEEQLKPIAAQLVSALNHLHQKKIIHRDLKPQNILVSDNS------------SIKLCDFGFARALS---RTTLVLNS
| ||.|.|            .||.|.. . .  |..... .||...|||||.||||||....              .|..|||||. .        .. .
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

IK------GTPLYMAPELVQ----EYPYT-EKIDIWSLGIILYELYYGKPPYFTD--SMY----NLIKM-------IINEPITWP-----GPISDEFKDF
..      ||||||||...|    . ||.  | ||||||.|.||. |||.|.|..  . |    .||..       | |.|| .|      .||.|.||.
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

ILKALVKDPDSRWSCEQLLNHPWI
| . |..|.. | | |...||||.
IRRMLQYDEKDRISWEEIFNHPWF
Kinase 93088.m00125.AA ULK 4-254 33 3.7e-95 322.46 In-house 1-329 (329) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-329/329
Sequence Identity: 33% (109 aa)

YKLIQQIGEGSFGRVFKARRKYT----GRMVAIKTIQKGNMKDEDLVN--------FRREVDILKKVD--------HPNIMRLLEYFETDSE--FCLVTE
| |....|.||||.|.|.| | |    . .||.| |.|  |. .   .        ...|..|.|| .        |||| .|...|||. .  . ...|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LGRG-DLFQIIS-------DT---QRLPEEQLKPIAAQLVSALNHLHQKKIIHRDLKPQNILVSDNS------------SIKLCDFGFARALSRT-----
.  | ||.|.|.       ||   .||.|.. . .  |..... .||...|||||.||||||....              .|..|||||. ..       
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

TLVLNS----IKGTPLYMAPELVQ----EYPYT-EKIDIWSLGIILYELYYGKPPYFTD--SMY-----NLIKM-------IINEPITWP-----GPISD
 ..  .    ..||||||||...|    . ||.  | ||||||.|.||. |||||...   . |     .||.        | ..|. .|      .||.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

EFKDFILKALVKDPDSRWSCEQLLNHPWI
|.||.| . |..|.. | | |.|.||||.
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 93088.m00125.AA STE 4-254 27 5.1e-90 305.38 In-house 1-359 (359) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-359/359
Sequence Identity: 27% (102 aa)

YKLIQQIGEGSFGRVFKARRKY---------------TGRMVAIKTIQKGNMK---------------DEDLVNFRREVDILKKVD--HPNIMRLLEYFE
...|..||.|.|| |.||...                ||...||| . . | .               .|.. .. .|..|.|| .  |||| . . ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TD-------SEFCLVTELGR-GDLFQIIS------DT--------QRLPEEQLKPIAAQLVSA-LNHLHQKKIIHRDLKPQNILVSDNSSIKLCDFGFAR
 .       .| ... |.   | | .||       ..        .|.||.|.. |. |.. . |..||...|||||.||.|||.     .||||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

ALSR---------------TTL-VLNSIKGTPLYMAPELVQE------YPYTEKIDIWSLGIILYELYYGKPPYFT-DSMYNLIKMIIN-----------
 |.                |.    |.. ||| .|||| .|        .|..| ||||||. . |.  ||||...   |...  ...|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----EPITWPGPIS-------------------DEFKDFILKALVKDPDSRWSCEQLLN--HPWI
    .| . | ..|                   .|||||| | |.|||. |.. .|||.  ||.|
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 93088.m00125.AA CAMKL 4-254 32 2.1e-89 285.48 In-house 1-297 (297) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-297/297
Sequence Identity: 32% (98 aa)

YKLIQQIGEGSFGRVFKARR-KYTGRMVAIKTIQKGNMK-DEDLVNF------------RREVDILKKVD---HPNIMRLLEYFETDSE------FCLVT
|......|.|||| |  |.  ..||..|||| | |  .. |.   .             |||. |.|...   ||||..|.| .||..       ..||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELGRGD---LFQIISDT----QRLPEEQLKPIAAQLVSALNHLHQKKIIHRDLKPQNILVSDNSS--IKLCDFGFARALSR----TTLVLNSIKGTPLYM
|.  |    ||. |       .|.||.. . .  |.|||.|..|...|.|||.|| |||...| .  ||..||||.    .    .   |.   |.| ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELVQE--YPYT-EKIDIWSLGIILYELYYGKPPYFTDS---------MYNLIKMIINEPITWPGPISDEFKDFILKALVKDPDSRWSCEQLLNHPWI
|||..|    ||   |.||||.|.||| . .|. |   |.          . ...|.  . .. .  .| . .|.| | |...|. | ...|..|||| 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 93088.m00125.AA Ciliate-E2 4-254 28 2e-86 293.41 In-house 1-365 (365) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-365/365
Sequence Identity: 28% (109 aa)

YKLIQQIGEGSFGRVFKARRKYTGRMVAIKTIQKGN-------------------MKDEDLVNFRREVDILK----------------KVDHPNIMRLLE
||.|..||.|.|| |.|.... .....||| |.  .                   ||  .. .. .| .|..                ...||||... |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

YFE--TDSEFCLVTELGRG-DLFQIIS------------DTQRLPEEQLKPIAAQLVS---------------ALNHLHQKK-IIHRDLKPQNILVSDNS
.|.  .|. . ||.|.  | |||..|             | ... |.. | | .|...               ||..||.|. |||||.||.|||.    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

SIKLCDFGFAR----------------------ALSRTTL---------VLNSIKGTPLYMAPELVQ---------EYPYTEKIDIWSLGIILYELYYGK
 ||..|||...                        |||.          . |.| ||| ||||| ..         . .|..|.||||||.||||. .||
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

PPYFTDSMYNLIKMIINEPITWPGP------------------ISDEFKDFILK----ALVKDPDSRWS-CEQLLNHPWI
||.        .. |.. .|  | |                  .|.| ||.| |     |.|||. | .  ||.|||||.
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 93088.m00125.AA MARK 4-254 39 4.4e-85 278.07 In-house 1-262 (262) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-262/262
Sequence Identity: 39% (103 aa)

YKLIQQIGEGSFGRVFKARRKYTGRMVAIKTIQKGNMKD-EDLVNFRREVDILKKVDHPNIMRLLEYFE--TDSE-FCLVTEL-GRGDLFQIISDT--QR
||....||.||.. | .|. | ||| ||||...| .. | . . |..||..|.||.||||| .|....|  | .  ..|. |. ..|.|.. |      |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LPEEQLKPIAAQLVSALNHLHQKKIIHRDLKPQNILVSDNS--SIKLCDFGFARALSRTTLVLNSIKGTPLYMAPELVQEYPYT-EKIDIWSLGIILYEL
|.||  . |  |.|||.| .|.| |.|||.||.|||. .|    ||..||||..     .. ||.  ||| |||||...  ||.  |.||||||..|| .
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQK-LNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

YYGKPPYFTDS--MYNLIKMIINEPITWPGPISDEFKDFILKALVKDPDSRWSCEQLLNHPWI
  |. |.  |.  . .| | | ..  . |  .|.| ...| . |. .|. | ..|....|||.
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 93088.m00125.AA NEK 4-254 35 8e-83 281.46 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-286/286
Sequence Identity: 35% (102 aa)

YKLIQQIGEGSFGRVFKARRKYTGRM-----VAIKTIQKGNMKDEDLVNFR-REVDILKKVDHPNIMRLLEYFETDS--EFCLVTELGR--GDLFQI---
|..|..||.||||.|.|.||| .|..     ...| |. |||....  |    || |||. .|||| .  . |. .    .| | |     |||.|    
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

ISDTQ----RLPEEQLKPIAAQLVSALNHLHQK-----KIIHRDLKPQNILVSDNSS----IKLCDFGFARALSRTTLVLNS-IKGTPLYMAPELVQEYP
|   .     ..|||   . .|...||...|..     ||.|||.|||||  ..| .    .|. ||| .. |..||  ...   ||| ||.||..|. |
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP

YTEKIDIWSLGIILYELYYG--KPPYFTD--SMYNLIKMIINE-PIT-WPGP--ISDEFKDFILKALVKDPDSRWSCEQLLNHPWI
|..| |||||| .|||.     |.|   .  .|..|.. |...      |     |.. ...| . | |||..| ||.|.|..| |
YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 93088.m00125.AA Pkinase_Tyr 4-200 31 8.4e-37 125.27 Pfam 1-216 (270) Show / Hide 
Range on Protein: 4-200
Range on HMM: 1-216/270
Sequence Identity: 31% (68 aa)

YKLIQQIGEGSFGRVFKARRK----YTGRMVAIKTIQKGNMKDED--LVNFRREVDILKKV-DHPNIMRLLEYFE-TDSE--FCLVTEL-GRGDLFQIIS
 ......|||.||.|.|.. |     |.  ||.|.. | .  .|.  .  | ||. |.|.  .|||| ||.      .     ..|.|.   |||     
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

D----TQRLPEEQLKPIAAQLVSALNHLHQKKIIHRDLKPQNILVSDNSSIKLCDFGFARAL-SRTTLVLNSIKGTPL---YMAPELVQEYPYTEKIDIW
.     |.|. ..|  ...|  .....|..|..|||||   |.||..|  .| |||| ||.. .  .  . . .|..|    ||||  ... .|.| |.|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SLGIILYELYY-GKPP-Y
| |. ..|..  |. | |
SFGVLMWEIFTYGEQPTY
Kinase 93088.m00125.AA TyrKc 4-254 25 3.3e-32 114.25 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-254
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

YKLIQQIGEGSFGRVFKARRKYTGRMVAIKTIQKGNMKDEDLVNFRREVDILKKV--DHPNIMRLLEYFETD-------SEFCLVTEL-GRGDLFQIISD
 .|....||| ||.|.|.. |   ..||.|.....      .  |.||  |..|.  .|||| ||. .  ..          ..|.|.   ||| . . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

TQR-LPEEQLKPIAAQLVSALNHLHQKKIIHRDLKPQNILVSDNSSIKLCDFGFARALSRT--------TLVLNSIKGTP--L---YMAPELVQEYPYTE
... |. ..|  .. |  .  ..||.|..|||||   |.||..|  .| .||| .|..           . .  . ||.   |    ||||  ... .|.
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KIDIWSLGIILYELY-YGKPPYFT-----DSMYNLIKMIINEPITWPGPI---------SDEFKDFILKALVKDPDSRWSCEQLLNHPWI
| |.|| |. ..|.. ||..||        | . .|. . .     . |          .||  . ...    ||..| . ...  |  .
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
HEAT 93088.m00125.AA HEAT 506-521 25 50.028601 0.49 Pfam 1-16 (31) Show / Hide 
Range on Protein: 506-521
Range on HMM: 1-16/31
Sequence Identity: 25% (4 aa)

FVQTLFKLLDDTKPHI
....|.|.|.|. ...
ILPHLLKCLNDPDWEV
HEAT 93088.m00125.AA HEAT 776-806 29 18.973678 1.95 Pfam 1-31 (31) Show / Hide 
Range on Protein: 776-806
Range on HMM: 1-31/31
Sequence Identity: 29% (9 aa)

ILELSLQDLENVSPFVRRRCCHFLGNVWRQG
||.. |. |.  .. ||. .|  ||.. .. 
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
Arm 93088.m00125.AA Arm 816-844 41 0.000815 16.62 Pfam 13-41 (41) Show / Hide 
Range on Protein: 816-844
Range on HMM: 13-41/41
Sequence Identity: 41% (12 aa)

AIPKLVKLASDNDEDVCASACYALSNAVY
..| ||.| ...||.|.  || ||.| . 
CVPPLVQLLHHPDEEVQENACWALWNLCA
HEAT 93088.m00125.AA HEAT 816-846 32 0.001652 16.01 Pfam 1-31 (31) Show / Hide 
Range on Protein: 816-846
Range on HMM: 1-31/31
Sequence Identity: 32% (10 aa)

AIPKLVKLASDNDEDVCASACYALSNAVYHT
 .| |.|. .|.|..| ..||..|.. . | 
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
Arm 93088.m00125.AA Arm 862-884 26 1.524672 5.45 Pfam 19-41 (41) Show / Hide 
Range on Protein: 862-884
Range on HMM: 19-41/41
Sequence Identity: 26% (6 aa)

DLLLKSNERAVECSASLISNLVS
.||  ..|. .| ..  ..||..
QLLHHPDEEVQENACWALWNLCA
Arm 93088.m00125.AA Arm 925-941 17 25.880461 1.25 Pfam 1-17 (41) Show / Hide 
Range on Protein: 925-941
Range on HMM: 1-17/41
Sequence Identity: 17% (3 aa)

TDEGKKLLKNSNAIKVL
..| |... .......|
NPEQKQAVIQCGCVPPL