Gene 96895.m00082 (T.vaginalis)

96895.m00082

Species: T.vaginalis
Alias: 96895.m00082, TvagK1030
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK-Unique

Sequence

Name Sequence Type Origin Length Description Download
96895.m00082.AA Protein None 260 None Fasta, JSON
96895.m00082.kin_dom Protein Kinase Domain None 234 None Fasta, JSON

Protein domain

Protein domains of 96895.m00082.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 96895.m00082.AA Ciliate-E2 13-246 17 2.2e-34 115.41 In-house 1-365 (365) Show / Hide 
Range on Protein: 13-246
Range on HMM: 1-365/365
Sequence Identity: 17% (67 aa)

YKIIQLLYNGATT-----QTYKVVS-------------------DAGLQFVAKFLQKKD-EHALTEIEIVKKMH----------------HKYILEFNNM
||.|... .|.       . .||                     ... ..  | ..|.. |. . || | ....                |..|...   
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LE--TDTEFVMLCPFYQSLALHYVQSID------------GFTPQRLATLFYKILV---------------GLKYIHNMK-IIHGDIRPENIIVSTENNE
 .  .|. . .   ..|   | .   .              || .  ......||                .|.|.|. . ||| || ||||..      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

ETPHIIDFGISHYEGQP----------------------------------FDNTLTTPAYKPP----EQD---------LTFKSDIYSLGLAFYVCFSQ
  . |||||.| .  ..                                  |.... || |..|     ..          ..|.||.|||  .| . . 
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

IQ---TASQIRMHQLFSEK-------------AWASSNPLLIDLIKN----MIERDVEKRFS-LEDCLNHPYF
        .    ......              | .  .  .||||.    |...| |||..  |..||||.|
KPPFQQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
S_TKc 96895.m00082.AA S_TKc 13-246 23 6.4e-34 119.92 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-246
Range on HMM: 1-231/231
Sequence Identity: 23% (61 aa)

YKIIQLLYNGATTQTYKVVSDA-GLQFVAKFLQKKDEHALTEIEIVKKMHHKYILEFNNMLETDTEFVMLCPFYQS---LALHYVQSIDG------FTPQ
|.|....  ||  . ||..    | ..  | .    ||.. ||.| || ||..|  .  . .. ... |   .        ..| ..  .      |.. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-

RLATLFYKILVGLKYIHNMKIIHGDIRPENIIVSTENNEETPHIIDFGISHYEGQPFDNTLTTPAYKPPEQ-DLTF-KSDIYSLGLAFYVCFS------Q
. . ..| |. .|.|.|...||| |. |||| ...     .  |.|||..       .    || | .||    .. |.|..|.|  .| ...      |
HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL----TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFPQ

IQTASQIRMHQLFSEKAWASSNPLLIDLIKNMIERDVEKRFSLEDCLN-------HPYF
.|.  .. .             | ..|.|... ..| ||| .  ..|.       ||.|
MQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 96895.m00082.AA CAMK 33-246 16 1.3e-28 88.78 In-house 30-425 (425) Show / Hide 
Range on Protein: 33-246
Range on HMM: 30-425/425
Sequence Identity: 16% (64 aa)

DAGLQFVAKFLQKK--------------------------------DEHALTEIEIVKK-------MHHKYILEFNNMLET-------------------
. | .. .|.. ||                                 .  . |||| ||       ..|. |. .  . |.                   
N-GQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTK

DTEFVMLC---PFYQSL----A-LHYVQSI---------------DGFTPQRLATLFYKILVGLKYIHNMKIIHGDIRPENIIVSTENNEE---------
|....|      . .        . |...                  || .  ...|  |. ...|.|...|.| |. |||| ... |...         
DKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIF

-----TPHIIDFGISHY--------------------------EGQPFDNTLTTPAYKP-PEQD------------------LTFKSDIYSLGLAFYVCF
     .  ||||| . .                          |||..     ||.| . ||                     ..|.|. |.|   |.. 
DWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIML

SQ----------------------IQTASQIRMHQL-FSEKAWASSN--------------------PLLIDLIKNMIERDVEKRFSLEDCLNHPYF
.                        ..  .|.  .  | .. .  .                     .  .|||..| ..| |||...|.||||| .
CGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 96895.m00082.AA Pkinase 13-246 20 1.4e-27 98.57 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-246
Range on HMM: 1-293/293
Sequence Identity: 20% (61 aa)

YKIIQLLYNGATTQTYKVVSDAGLQ-FVAKFLQKKDEHALT--------EIEIVKKMHHKYILEFNNMLETDTEFVMLCPFY--Q----SLALHYVQ--S
|.|.. .  |.  . || .     . .. | . |..|.           ||.| |...|..|...  . |....  |  ..        .|. .|..  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF-DYISTWR

IDGF--TPQRLATLFYKILVGLKYIHNMKIIHGDIRPENIIVS-TENNEETPHIIDFGIS----HYEGQPFDNTLTTPAYKPPEQDL-----TFKSDIYS
  .|  ... .   .| || ||.|.|.|.||| |. |||| .. . ..... .|.|||..    .  .. ..    || | .||  .     . |.|..|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGLAFYVCFSQIQTASQI------RMHQLFSEKAW--------ASSN-------------------PLLIDLIKNMIERDVEKRFSLEDCLNHPYF
.|. .|  ..     ..       .. |.. .. .         ...                   . ..|.||.....| .|| . |..|.||.|
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 96895.m00082.AA Ciliate-E2-Unclassified 13-246 19 2.4e-23 77.85 In-house 1-352 (352) Show / Hide 
Range on Protein: 13-246
Range on HMM: 1-352/352
Sequence Identity: 19% (69 aa)

YKIIQLLYNGATTQTYKVVSDAGLQF--------VAKFLQKKDEH---------ALTEIE-------------IVKKMHHKYILEFNNMLETDTEFVMLC
||||. . .|.  . ||.. .   |.        . .. ||. ..         .. ...             | . . | .|. .  . ...  . .  
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

PFYQSLALHYVQSIDG------------------FTPQRLA-----TLFYKILVGLKYIHNMK-IIHGDIRPENIIVSTENNEETPHIIDFGISHYEGQP
 . . . |..  .. .                  || |  .     ..|. ||.||.|.|  . ||| || ||||... ...   . ||||||| . .|.
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

------------------FDNTLTTPAYK----PPE----QDLT----FKSDIYSLGLAFYVC------FSQIQTAS----------------QIRMHQ-
                  .. .  || |.    .||    |       .|.||.|||  .| .      |.. .  .                ...  . 
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

---LFSEKAW----ASSNPLLIDLIK----NMIERDVEKRFSLEDCLNHPYF
    |..  |      ..|  .|.|.     |.. . .|| ..|. ||||.|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 96895.m00082.AA ULK 101-246 21 1e-14 47.89 In-house 128-329 (329) Show / Hide 
Range on Protein: 101-246
Range on HMM: 128-329/329
Sequence Identity: 21% (44 aa)

PQRLATLFYKILV-GLKYIHNMKIIHGDIRPENIIVSTEN---NEETPH--------IIDFGISHYEGQP------FDNTL------TTPAYKPPE---Q
..  |  | | .. |.|..| ..||| || |.|| ..  .   ...           | ||| .     .      .  ..       || |  |.   .
SEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSK--KVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQG

D-----LT-FKSDIYSLGLAFYVCFSQI-----QTASQIR---MHQLFS-----------EKAWAS-------SNPLLIDLIKNMIERDVEKRFSLEDCL
       . .|.||.|||  || .         . ...     . .|.            ..             | ..|||. |...| ..|.| |. .
QGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELF

NHPYF
||| |
NHPWF
Kinase 96895.m00082.AA STE 51-186 21 1.8e-12 40.47 In-house 76-256 (359) Show / Hide 
Range on Protein: 51-186
Range on HMM: 76-256/359
Sequence Identity: 21% (41 aa)

LTEIEIVKKMH--HKYILEFNNMLETD-------TEFVMLCPFYQ-SLALHYVQS--IDGFT------------PQRLATLFYKILVG-LKYIHNMKIIH
| ||.| ||..  |..| ..  . . .       .|  .   .     .   ...  . |..             . .|.  . || | |.|.|...|||
LKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIH

GDIRPENIIVSTENNEETPHIIDFGISH------------------YEGQPFDNTLT-TPAYKPPEQDLT----------FKSDIYSLGL
 || | || .          ..|||..                   . .|   ||.. || .  ||  .           .|.||.|||.
RDIKPANILL--------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGC
Kinase 96895.m00082.AA Ciliate-E2a 220-246 48 2.4e-11 29.66 In-house 249-275 (275) Show / Hide 
Range on Protein: 220-246
Range on HMM: 249-275/275
Sequence Identity: 48% (13 aa)

IDLIKNMIERDVEKRFSLEDCLNHPYF
.||.| | | | .||.. ...||||.|
KDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 96895.m00082.AA Ciliate-E2a 110-189 28 6.7e-11 28.34 In-house 109-207 (275) Show / Hide 
Range on Protein: 110-189
Range on HMM: 109-207/275
Sequence Identity: 28% (28 aa)

KIL-VGLKYIHNMKIIHGDIRPENIIVS--TENNE--ETPHIIDFGISHYE--GQP-FDNTLT-TPAYKP------PE----QDLTFKSDIYSLGLAFY
..|  || |.|. .|.| |..||||.      |.       ||||| . .    .. .  .   || | .      .|    .. . | |. |.|. ||
QLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFY
Kinase 96895.m00082.AA CAMKL 114-172 36 7.8e-11 30.65 In-house 200-264 (297) Show / Hide 
Range on Protein: 114-172
Range on HMM: 200-264/297
Sequence Identity: 36% (24 aa)

GLKYIHNMKIIHGDIRPENIIVSTENNEETPHIIDFGIS-HYE------GQPFDNTLTTPAYKPPE
...|.|...|.| || |||| ..  .|. .  ||||| | .|.      || ..    .|.| .||
AVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPE
Kinase 96895.m00082.AA CMGC 50-165 14 1e-10 30.48 In-house 68-284 (513) Show / Hide 
Range on Protein: 50-165
Range on HMM: 68-284/513
Sequence Identity: 14% (32 aa)

ALTEIEIVKKM-----------------HHKYILEFNNMLETDT-----------------EFVMLCPFYQSLALHYVQSID---------GFTPQR---
|| ||.| |..                 ||..|.   ... ..                  .. .   . .   ..| ..           ....     
ALREIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENK

---------LATLF------YKILVGLK--YIHNMK--IIHGDIRPENIIVSTENNE-----------------ETPHIIDFGISHYEGQPFDN------
            ..      | || |||  |.| ..  ||| |. |||| .. ..                    .  |.||| . ..... |.      
HPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQP

--------------TLTT
              ..|.
QSFKNVNKDDKPNRPYTH
Kinase 96895.m00082.AA CAMKK-Unclassified 216-246 32 5.3e-10 28.46 In-house 362-392 (392) Show / Hide 
Range on Protein: 216-246
Range on HMM: 362-392/392
Sequence Identity: 32% (10 aa)

NPLLIDLIKNMIERDVEKRFSLEDCLNHPYF
.....|||..|.. . .|| .... |.||.|
SHEFKDLIQKMCDKNPKKRITIDQMLVHPWF
Kinase 96895.m00082.AA CMGC 216-246 48 9.2e-10 27.3 In-house 483-513 (513) Show / Hide 
Range on Protein: 216-246
Range on HMM: 483-513/513
Sequence Identity: 48% (15 aa)

NPLLIDLIKNMIERDVEKRFSLEDCLNHPYF
.|..|||.|.| . | .|| . |..|.||||
DPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 96895.m00082.AA ULK 101-191 25 1.1e-09 30.65 In-house 124-245 (324) Show / Hide 
Range on Protein: 101-191
Range on HMM: 124-245/324
Sequence Identity: 25% (31 aa)

PQRLATLFYKILV-GLKYIHNMKIIHGDIRPENIIVSTEN---NEETPH--------IIDFGISHYEGQP-FDNTLT-----------TPAYKPPE--Q-
..  |  | | .. |.|..|...||| || |.|| ..  .   . .           | ||| .     . .. ...           || |  |.  | 
SEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSK--KVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQG

-----DLT-FKSDIYSLGLAFYVC
     . . .|.||.|||  || .
QGEQKPYYDYKCDIWSLGCIFYEM
Kinase 96895.m00082.AA CAMKL 219-246 35 1.6e-09 26.43 In-house 270-297 (297) Show / Hide 
Range on Protein: 219-246
Range on HMM: 270-297/297
Sequence Identity: 35% (10 aa)

LIDLIKNMIERDVEKRFSLEDCLNHPYF
..|||. | ... |||..... .||| .
CRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 96895.m00082.AA CAMKK-Unclassified 114-153 34 5e-09 25.22 In-house 190-252 (392) Show / Hide 
Range on Protein: 114-153
Range on HMM: 190-252/392
Sequence Identity: 34% (22 aa)

GLKYIHNMK---------------------IIHGDIRPENIIVSTENN--EETPHIIDFGISH
||.|.|| .                     ||| || |.||  . | |   | . |.|||||.
GLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISV
Kinase 96895.m00082.AA ULK 219-246 42 2e-06 19.24 In-house 297-324 (324) Show / Hide 
Range on Protein: 219-246
Range on HMM: 297-324/324
Sequence Identity: 42% (12 aa)

LIDLIKNMIERDVEKRFSLEDCLNHPYF
..|||. |...| ..|.| |. .||| |
CKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 96895.m00082.AA TyrKc 13-246 17 5.9e-05 -142.51 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-246
Range on HMM: 1-280/280
Sequence Identity: 17% (51 aa)

YKIIQLLYNGATTQTYKVVSDAGLQFVAKFLQKKDEHA--LTEIEIVKKM--HHKYILEFNNMLETD-------TEFVMLCPFYQSLALH-YVQSIDG-F
 . .. | .||  . || . .  .|   | |..   ..  . |..| .|   ||. |. .     ..           ..  .    .|. | ..  . .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

TPQRLATLFYKILVGLKYIHNMKIIHGDIRPENIIVSTENNEETPHIIDFGISHYEGQP------FDNTLT--TPAYK--------PPE--QDL--TFKS
... |    . |  |  |.| ...|| |.   |. |. ..   |  | ||| | . .         |   .  .   |        .||  ..   |.||
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

D----------IYSLGLAFYVC-----FSQIQTASQIRMHQLFSEKAWAS--------SNPLLIDLIKNMIERDVEKRFSLEDCLNHPYF
|          |...|   |        | ..   ...  | .  .  ..          . . ...|   ..| |.| . ...  | .|
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVK--QGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 96895.m00082.AA STE 217-246 28 6.5e-05 13.42 In-house 328-359 (359) Show / Hide 
Range on Protein: 217-246
Range on HMM: 328-359/359
Sequence Identity: 28% (9 aa)

PLLIDLIKNMIERDVEKRFSLEDCLN--HPYF
| ..| |..  ..| .|| . .. |.  || .
PEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 96895.m00082.AA ULK 39-80 18 0.000328 10.91 In-house 36-94 (324) Show / Hide 
Range on Protein: 39-80
Range on HMM: 36-94/324
Sequence Identity: 18% (11 aa)

VAKFLQKKDEHA----------LTEIEIVKKMH---HKY--ILEFNNMLETDTE--FVM
. |. ..|...             ||.|.||..   |..  | ..  ..||...  . .
IDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYI
Kinase 96895.m00082.AA ULK 53-80 26 0.00545 6.38 In-house 60-97 (329) Show / Hide 
Range on Protein: 53-80
Range on HMM: 60-97/329
Sequence Identity: 26% (10 aa)

EIEIVKKMH----HKY----ILEFNNMLETDTE--FVM
||.| ||..    ||.    | ..  ..||...  . .
EIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYI