Gene 86045.m00057 (T.vaginalis)

86045.m00057

Species: T.vaginalis
Alias: TvagK0534, 86045.m00057
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
86045.m00057.AA Protein None 342 None Fasta, JSON
86045.m00057.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of 86045.m00057.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 86045.m00057.AA CAMKL 24-270 29 1.1e-71 228.0 In-house 1-293 (297) Show / Hide 
Range on Protein: 24-270
Range on HMM: 1-293/297
Sequence Identity: 29% (87 aa)

YKIIKTLGKGGFAVVVLAYD-TTTNQKVAFKVIDRQEVN-ETGTIKF-----------VECELRLLARLS---HNNIVKIYDIIYEPEM------IMIVM
|.|.||||||.|..| || .  ||..||| |.||..  . .. . |            .. | ... .|.   | ||.|.|..|. ||.      | .||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYLPNGD--IQTLVNNS----VSLRYDEYLNYTEDLLNALNYLHKRGIAHRDIKPDNILFSQDM--MIKIIDFGLS---KDN----QIPENLLLGTPMYM
|| ..|.   .  . .      ..  .|   |   .. |.||.|..||.||||||.|||.....   |||||||.|   ...        .   |.| ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APELFKS--LDSDPMMSDVWSLGVTLHIFMTGRYPWRYAN---------EMEFIRAVKHNNVMINIEIGGILGRVLEHMLEVNPNERSNCQDLLN
|||.|..   . |    |.||.||.|   ..|..|.. ..         ... .  .   .  | ...   . . . .||.|||..| ......|
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN
S_TKc 86045.m00057.AA S_TKc 24-272 25 2e-70 241.19 SMART 1-231 (231) Show / Hide 
Range on Protein: 24-272
Range on HMM: 1-231/231
Sequence Identity: 25% (68 aa)

YKIIKTLGKGGFAVVVLAYDTTTNQKVAFKVIDRQEVNETGTIKFVECELRLLARLSHNNIVKIYDIIYEPEMIMIVMEYLPN--GDIQTLVNNSVS---
|.|....|||.|..| ..... |...|| |.|.          . .. |...| .  | ||||.||.... . . .||||...  ||  ..  .  .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LRYDEYLNYTEDLLNALNYLHKRGIAHRDIKPDNILFSQDMMIKIIDFGLSKDNQIPENLLLGTPMYMAPELFKSLDSDPM-MSDVWSLGVTLHIFM
   .   .   |.  ...||.|.|..|| |||.||.|||...   |||.||||..      . . ||| |||||..    .     .|.||.|..| ...
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

TGRYPWRYANEMEFIRAVKHNNVMINIEIGGILGRVLEHMLEVNPNERSNCQDLLN---------LI
.|. |..  .... .. ..             .   ....|...|..|  . ..|.          .
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 86045.m00057.AA Pkinase 24-272 24 2.8e-67 234.62 Pfam 1-293 (293) Show / Hide 
Range on Protein: 24-272
Range on HMM: 1-293/293
Sequence Identity: 24% (73 aa)

YKIIKTLGKGGFAVVVLAYDTTTNQKVAFKVIDRQEVNETGTIKFVE-CELRLLARLSHNNIVKIYDIIYEPEMIMIVMEYLPNG----DIQTLVN--NS
|.|....|.|.|..| ....  |...|| |.|.... ..   .  .   |.....||.| |||..||. ...  | .||||...|    |  ...   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

VSL--RYDEYLNYTEDLLNALNYLHKRGIAHRDIKPDNILFSQDMMI----KIIDFGLS----KDNQIPENLLLGTPMYMAPELFKSLDSDPMMSDVWSL
 ..   ..|  .|   .| .|.|.|..|| |||.||.|||..... |    ||.||||.      |.   . . ||| |||||. ..   ..  .|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVTLHIFMTGRYPWRYA------NEMEFIRAVKHNNVMINIEIG---------------------GILGRVLEHMLEVNPNERSNCQDLLNL--I
|..|.....|| |.. .      ..|. |. ...  .. ...                         .  ... .|...|..| .....|.   .
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 86045.m00057.AA CAMK 29-270 19 1.1e-62 200.57 In-house 1-421 (425) Show / Hide 
Range on Protein: 29-270
Range on HMM: 1-421/425
Sequence Identity: 19% (80 aa)

TLGKGGFAVVVLAYDTTTN------------QKVAFKVIDRQEVNE-------------------------TGTIKFVECELRLLARLS-------HNNI
|||.|.|..| |.... |.            |||| |.||.. . .                           . |.|. |.... .|.       | ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKIYDIIYE-------------------PEMIMIVM---EYLPNGDI-QTLVNNSVSLRY------------DEYL------NYTEDLLNALNYLHKRGI
.|.|...                     .... .||   || ..|.  . | .  |. ..            . ..       |   .. |..|.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDIKPDNILFSQDM-----------------MIKIIDFGLSKDNQIPENL--------------------------LLGTPMYMA-PELFKS------
.|||.||.|||.....                  |||||||...  .  ||.                            ||| ||| ||....      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------LDSDPMMSDVWSLGVTLHIFMTGRYPWRYA-------------NEMEFIRAVKHNNVM-INIEIGGI-----------------------LGR
        . ..  .|.||.|| | |  .|..|..               |. |  . ..  .   .  .. .|                          
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

VLEHMLEVNPNERSNCQDLLN
 . .||.|.|..| .... ||
LIRKMLQVDPEKRMTIEQCLN
Kinase 86045.m00057.AA Ciliate-E2 24-274 20 4.1e-61 208.54 In-house 1-365 (365) Show / Hide 
Range on Protein: 24-274
Range on HMM: 1-365/365
Sequence Identity: 20% (78 aa)

YKIIKTLGKGGFAVVVLA--YDT---------------------TTNQKVAFKVIDRQEVNETGTIKFVE----------CELRLLARLSHNNIVKIYDI
||.|| .|.|.|..| ..  . .                     ......| |..  ......  .. .            |...| .|.|.||.|.|. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IY--EPEMIMIVMEYLPNGDIQTLVNNS-----------VSLRYDEYLNYTEDLLN---------------ALNYLHKRG-IAHRDIKPDNILFSQDMMI
 .    . | .||||.  || . . .|.            ..   | ..... .|.               ||.|||... | ||||||.||||     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIIDFGLSKDNQIP--ENL--------------------------------LLGTPMYMAPELFKSLDSDP--------MMSDVWSLGVTLHIFMTGRYP
|||||||||.....  ...                                ..|||.||||| ... . |          ..|.|||||.|.....|..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WRYANEMEFIRAVKHNNVMINIEIGGILG----------------------------RVLEH----MLEVNPNERSN-CQDLLNLINS
.                  ... . . .                               .      ||...|..| .  ...||    
F------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 86045.m00057.AA ULK 24-262 24 1.3e-54 187.75 In-house 1-317 (329) Show / Hide 
Range on Protein: 24-262
Range on HMM: 1-317/329
Sequence Identity: 24% (77 aa)

YKIIKTLGKGGFAVVVLAYDTTT----NQKVAFKVIDRQEVNETG-------TIKFVECELRLLARLS----HNN----IVKIYDIIYEPEM--IMIVME
| ... |||| |..|  ...  |    |.||| |.||.|. |.          ..... | ... .|     |.|    ||| ||. ...    | |.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YLPNGDIQTLVN----------NSVSLRYDEYLNYTEDLLNALNYLHKRGIAHRDIKPDNILFSQD------------MMIKIIDFGLSKDNQIP-----
| . || ... .          .   |  .| ...  ..||.. .|||..| ||||||.||| . .            . .|| |||..|  . .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-ENLLL------GTPMYMAPELFKSL--DSDPM-M-SDVWSLGVTLHIFMTGRYP---WRYANEM-----EFIRA-------VKHNNVMIN-----IEIG
 .   .      |||.||||......    ..    .|.||||. ..   .|..|   | .  .      . |.        .| ..  ..     . | 
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

GILGRVLEHMLEVNPNER
  .   .  ||......|
PECKDLIRRMLQYDEKDR
Kinase 86045.m00057.AA ULK 24-262 24 1.3e-53 184.43 In-house 1-312 (324) Show / Hide 
Range on Protein: 24-262
Range on HMM: 1-312/324
Sequence Identity: 24% (76 aa)

YKIIKTLGKGGFA-VVVLAYDTTT---NQKVAFKVIDRQEVNETGT-------IKFVECELRLLARLS---HNN--IVKIYDIIYEPEM--IMIVMEYLP
| ... |||| |. .|  ...  |   ||.|| |.||... |.          ... . | ...  |    |.|  ||| ||. ...    | |.||| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGDIQTLVNNSVS---------LRYDEYLNYTEDLLNALNYLHKRGIAHRDIKPDNILFSQD------------MMIKIIDFGLSKDNQIPE---NLL--
 || ... ..            |  .| ...  ...|.. .|||..| ||||||.||| . .              .|| |||..|  . ..   ...  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

-L------GTPMYMAPELFKSL--DSDPM-M-SDVWSLGVTLHIFMTGRYP---WRYANEM----EFIRA-------VKHNNVMIN-----IEIGGILGR
 .      |||.||||......    ..    .|.||||. ..   .|.||   | . ..     . |.        .| ... ..     . |   .  
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

VLEHMLEVNPNER
 .  ||......|
LIRRMLQYDEKDR
Kinase 86045.m00057.AA Ciliate-E2-Unclassified 24-270 22 4.6e-53 182.41 In-house 1-348 (352) Show / Hide 
Range on Protein: 24-270
Range on HMM: 1-348/352
Sequence Identity: 22% (79 aa)

YKIIKTLGKGGFAVVVLAYDTTTNQKV-----AFKVIDRQEVNETGTIKFVECELRLLAR----------------LSHNNIVKIYDIIYE--PEMIMIV
|||||..|.|||..| ....  .. ..     . |....   .    . .. .....  .                |.|......... ..   . | ||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYLPNGDIQTLVNNSVS-----------LRYDEYL-----------NYTEDLLNALNYLHKRG-IAHRDIKPDNILFSQDM---MIKIIDFGLSK---D
|||...|| .   ... .           ..... .           .|.  .|..|.|||. . | ||||||.||||....    |||||||.||   .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

N------------QIPENLL---LGTPMYM----APELFKSLDSDPM---MSDVWSLGVTLHIFMTGRYPWRYANEME----------------FIRAVK
|            .......    |||.||    |||....   | .   ..|.||||| |. ...|.||  . |. .                ...  |
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

HNNVM----------INIEIGG--ILGRVLEHMLEVNPNERSNCQDLLN
 .|.            ..   .  .. . |  ||..|||.| . ...||
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN
Kinase 86045.m00057.AA QIK 24-219 34 3.9e-47 162.92 In-house 1-217 (272) Show / Hide 
Range on Protein: 24-219
Range on HMM: 1-217/272
Sequence Identity: 34% (75 aa)

YKIIKTLGKGGFAVVVLAYDTTTNQKVAFKVIDRQEVNETGTIKFVECELRLLARLSHNNIVKIYDIIYEPEMIMIVMEYLPNGDIQTLVNN--------
| | .|.||| |||| ||    | .||| |.||.   .|.  .| .. |  .. .|.| .|.| |...   .|. ||.|| .||..   ...        
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQK-CYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

------------SVSLRYDEYLNYTEDLLNALNYLHKRGIAHRDIKPDNILFSQDMMIKIIDFGLSKDNQIPENLL---LGTPMYMAPELFKSLDSDPMM
             | .  .|      ... |  |.|||.|.|||.|  |||. ..| |||.|||.|   . .. ||    |.| | |||.|.  . | . 
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFS-NWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK

SDVWSLGVTLHIFMTGRYP
.|.||.|| | .  .|  |
VDIWSMGVVLYVLVCGALP
Kinase 86045.m00057.AA STE 24-220 21 1.6e-44 154.2 In-house 1-268 (359) Show / Hide 
Range on Protein: 24-220
Range on HMM: 1-268/359
Sequence Identity: 21% (60 aa)

YKIIKTLGKGGFAVVVLAYDT------TTNQK---------VAFKVID--RQEVNETG-------------TIKFVECELRLLARLS--HNNIVKIYDII
...|. .|||.| .|..|..        |...         .| |...  ... ..                .. .. |.... ...  | |||| |.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

YEP-------EMIMIVMEYLPNGDIQTLVNNSVSLRY-------------DEYL-NYTEDLLNA-LNYLHKRGIAHRDIKPDNILFSQDMMIKIIDFGLS
.         . . |.|||...| .  ....  .                 . .  .. ..| . |.|||. .| ||||||.|||.     .|..|||..
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

K-------------------DNQIPENLLLGTPMYMAPELFKSLDSDPM------MSDVWSLGVTLHIFMTGRYPW
.                   ..|   | . ||| .||||  .  ...         .|.|||| |.    ||..||
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPW
Kinase 86045.m00057.AA TKL 30-272 18 2.1e-44 153.87 In-house 1-364 (364) Show / Hide 
Range on Protein: 30-272
Range on HMM: 1-364/364
Sequence Identity: 18% (68 aa)

LGKGGFAVVVLA-YDTTT-------NQKVAFKVIDRQEVNETG------------------------TIKFVECELRLLARLSHNNIVKIYDIIYEPEM-
.|.|||..|  . .  ..       .. || |.. .....|.                           .| | |.... ||.| |||... .  .|.  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------IMIVMEYLPNGDIQTLVNNSVSLRYDEYLNYTEDLLNALNYLHK--------RGIAHRDIKPDNILFSQDMM--------------IK
            ..||||| |.|.   ...       .  ..   |   ..||||         ..|.|||.|..|||  ...               .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

IIDFGLSKDNQIP----------------------ENLLLGTPMYMAPELFKSLDSDP---------------MMSDVWSLGVTLHIFMTGRYPWRYANE
| |||||....                         .   ||| .||||...  . ..                 .||.| |. |   .|.. |..  ..
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

M---------EFIRAVKHNNVMINIE--------------IGGILGRVLEHMLEVNPNERSNCQDLLNLI
|         |..  | ...    |               .   . . ...  . .|..| ..|..|  .
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 86045.m00057.AA MARK 131-228 41 4.6e-32 102.24 In-house 113-218 (262) Show / Hide 
Range on Protein: 131-228
Range on HMM: 113-218/262
Sequence Identity: 41% (45 aa)

LLNALNYLHKRGIAHRDIKPDNILFSQDM--MIKIIDFGLSKDNQIPENLLL----GTPMYMAPELFKSLDSDPMMSDVWSLGVTLHIFMTGRYPWR--Y
.. |.||.|...|.||||||.|||  ...   |||||||.|  ..||.. .|    ||| |||||.|.. . |    |.||||| | .  .|..|..   
IVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFS--ICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDT

--ANEMEF
   .|...
QDYKELYK
Kinase 86045.m00057.AA MARK 24-108 34 1.2e-29 94.26 In-house 1-88 (262) Show / Hide 
Range on Protein: 24-108
Range on HMM: 1-88/262
Sequence Identity: 34% (30 aa)

YKIIKTLGKGGFAVVVLAYDTTTNQKVAFKVIDRQEVNETGTIKFVECELRLLARLSHNNIVKIYDIIY--EPEM-IMIVMEYLPNGD
||..||.|.|..|.| || .. |..||| |.....  |.  ..| |. |.... .|.| ||.| ...|   ...  | ..||| ..|.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGE
Kinase 86045.m00057.AA Pkinase_Tyr 24-171 27 3.4e-17 58.84 Pfam 1-160 (270) Show / Hide 
Range on Protein: 24-171
Range on HMM: 1-160/270
Sequence Identity: 27% (44 aa)

YKIIKTLGKGGFAVVVLAYDT----TTNQKVAFKVIDRQEVNETG--TIKFVECELRLLARL-SHNNIVKIYDIIY-EPEM--IMIVMEYLPNGDIQTLV
 ...|.||.| | .|.... .     |...|| |.. ..   .      .| . |....  | .| |||. | ... . |   |.||||| |.||  .  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

NN----SVSLRYDEYLNYTEDLLNALNYLHKRGIAHRDIKPDNILFSQDMMIKIIDFGLSKD
 .      .|   . |..  .  ....||. ... |||.   |.| . .. .|| ||||..|
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD
Kinase 86045.m00057.AA TyrKc 24-272 23 2.6e-16 40.99 SMART 1-280 (280) Show / Hide 
Range on Protein: 24-272
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YKIIKTLGKGGFAVVVLAYDTTTNQKVAFKVIDRQEVNETGTIKFVECELRLLARL--SHNNIVKIYDIIYEP-------EMIMIVMEYLPNGDIQTLV-
 . .|.|| | | .|...  .   ..|| |..          ..    |.|.. .|  .| |||..| .. ..       | .|||||| |.|| .    
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NNSVSLRYDEYLNYTEDLLNALNYLHKRGIAHRDIKPDNILFSQDMMIKIIDFGLSKDNQIP-------ENLLL----GTPM-----YMAPELFKSLDSD
..   |  .. |..  .  .  .|||.... |||.   |.| . .  .|| |||||.|           .        |. .      |||| ..     
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PMMSDVWSLGVTLH-IFMTGRYPWRY-----ANEMEFIRAVKHNNVMINIEI---------GGILGRVLEHMLEVNPNERSNCQDLLNLI
.  ||||| ||..  ||  |  |.        .  | |. ||. . |   .             . .. .   . .|..| . ...  ..
T-KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 86045.m00057.AA Pkinase_Tyr 201-210 70 2.686705 1.63 Pfam 195-204 (270) Show / Hide 
Range on Protein: 201-210
Range on HMM: 195-204/270
Sequence Identity: 70% (7 aa)

SDVWSLGVTL
||||| ||..
SDVWSFGVLM