Gene 85699.m00080 (T.vaginalis)

85699.m00080

Species: T.vaginalis
Alias: 85699.m00080, TvagK0048
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
85699.m00080.AA Protein None 391 None Fasta, JSON
85699.m00080.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 85699.m00080.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85699.m00080.AA AGC 13-266 23 6.9e-107 276.84 In-house 1-395 (395) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-395/395
Sequence Identity: 23% (94 aa)

YILRQRIGEGAFSSVWLADCKD-----VSIPA-AVKIISKST-LDQPD--VFTRFQRE------------ISLLQQCS----------HPFITH-FYELY
. .   ||.|.|. |.|.  ||      .    |.|...|..   . .     . ..|               |..|.          ||||..  .  .
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EDTNR--YYVFMEYAE--------NGDFESFLQTRG-----RLPENMSRFFFAQ-------LITALDYLHNTCRIAHRD-LKPQNILLDRYNNIRITDFG
.| ..   |  |||..         |..|.||. .|     |..|...||..|.       .. ||.|||.   | ||| ||| |||||.  .|..||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKAFND--------------------------------------------------VVPNLTSNCG--SPAYAAPEVIIGKPYNKAADVWS--LGVILY
|.| ...                                                       .. ||  .| | |||..    |.||.| ||  ||...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

QMATGHLPFQSP----------DVKTVLMKIV------SFDPPYP----------PTMSSQLIDLLRRMLCRNPSKRIT----------IKEIMEHPWV
.| ||. ||..           . . .  ||       ......|          . .|... ||....||..|.||..          ..||..||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 85699.m00080.AA CAMKL 13-266 34 3.4e-105 336.67 In-house 1-297 (297) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-297/297
Sequence Identity: 34% (105 aa)

YILRQRIGEGAFSSVWLADCKDV-SIPAAVKIISKSTLD-QPDVFTR-----------FQREISLLQQCS---HPFITHFYELYEDTNR------YYVFM
|.. . .|.|.|. | ||  .    .  |.||| |. .   | .  .            .|||..... .   || | ..|| .|. .       .| .|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAENGD--FESFLQTR----GRLPENMSRFFFAQLITALDYLHNTCRIAHRDLKPQNILLD-RYN-NIRITDFGLSKAFND--VVPN--LTSNCGSPAY
||...|.     ... .    ||.||.  |..| |.. |..|.|. . |.|||.|| ||||| . | || |.|||.|  . .  . |.  |.  ||||.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

AAPEVIIG--KPYN-KAADVWSLGVILYQMATGHLPFQSP-------DVKTVLMKIVSFDPPYPP---TMSSQLIDLLRRMLCRNPSKRITIKEIMEHPW
.|||.. |  |||. ...|.||.||||| | .|.|||  .       | .  |....  .  |||    .| ...||.|.|| .||.||.||..||.|||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

V
.
M
S_TKc 85699.m00080.AA S_TKc 13-266 34 4.3e-105 356.37 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-231/231
Sequence Identity: 34% (93 aa)

YILRQRIGEGAFSSVWLADCKDVSIPAAVKIISKSTLDQPDVFTRFQREISLLQQCSHPFITHFYELYEDTNRYYVFMEYAEN--GDFESFLQTRGR---
| . . ||.|||..|...  |.     |.|||.           ...|||..|..  ||.| ..|. ..| ...|..|||...  ||  .... |||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LPENMSRFFFAQLITALDYLHNTCRIAHRDLKPQNILLDRYNNIRITDFGLSKAFNDVVPNLTSNCGSPAYAAPEVIIGKPYNK-AADVWSLGVILY
   .|| . ||...|.. ||.|.|.  .| ||||||.|||||.  .| |.||||.. .       |. ||.| | ||||.   .|.| ..|.||.|.|||
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

QMATGHLPFQSPDVKTVLMKIVSFDPPYPPTMSSQLIDLLRRMLCRNPSKRITIKEIME-------HPWV
 |..|  ||.  ...... ||.          |....|..|..|...|.||.|. |...       |||.
EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 85699.m00080.AA CAMK 18-266 23 3.1e-102 330.29 In-house 1-425 (425) Show / Hide 
Range on Protein: 18-266
Range on HMM: 1-425/425
Sequence Identity: 23% (100 aa)

RIGEGAFSSVWLADCKDVS------------IPAAVKIISKSTLD-------------------------QPDVFTRFQREISLLQQCS-------HPFI
 .|.|.|. | |.  |                  |.|||.|. |.                         .|    ...|||.......       || |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

THFYELYED-------------------TNRYYVFM---EYAENG----DFESFLQTR---------------GRLPENMSRFFFAQLITALDYLHNTCR
 ..|| |||                   ....| .|   ||...|    |  .... .               ||..|   |..| |.. |..|.|.   
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-

IAHRDLKPQNILLDRY-----------------NNIRITDFGLSKAFNDVVPN-----------------------LTSNCGSPAYAA-PEVIIG-----
|.|||||| |||||                   ||| |.|||... |..   |                       ..  ||.|.|.| |||. |     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------KPYNKAADVWSLGVILYQMATGHLPFQSP-------------DVKTVLMKIVSFDPP-YPPTMSS-----------------------QLI
         ..|....|.||.||||| | .|..||...             . .  . || . .   .|| .|                        . .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLLRRMLCRNPSKRITIKEIMEHPWV
||.|.||...|.||.||.....|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 85699.m00080.AA AMPK 13-266 41 7.6e-96 285.03 In-house 1-254 (254) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-254/254
Sequence Identity: 41% (105 aa)

YILRQRIGEGAFSSVWLADCKDVSIPAAVKIISKSTLDQPDVFTRFQREISLLQQCSHPFITHFYELY-EDTNRYYVFMEYAENGDFESFLQTRGRLPEN
||. . ||||.|  | ..  .  .   |.||. |  . . |.  | ||||..|.   || |.  ||   | .   ...|||. .|.  ..   .|||.| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

MSRFFFAQLITALDYLHNTCRIAHRDLKPQNILLDRYNNIRITDFGLSKAFNDVVPNLTSNCGSPAYAAPEVIIGKPYN-KAADVWSLGVILYQMATGHL
 .. ||.| | ...|.|.   |.|||||| |.|||  .|| | |||||.  .|    |   |||| |||||.| ||.|.    |.|| ||||| |  | |
EACRFFQQIISGVEYCHR-HMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDG-EFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYL

PFQSPDVKTVLMKIVSFDPPYPPTMSSQLIDLLRRMLCRNPSKRITIKEIMEHPWV
||  ... |   ||.. ... |  .|..  ||...||. .| |||||..|..||| 
PFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 85699.m00080.AA Pkinase 13-266 31 4.7e-95 326.89 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-293/293
Sequence Identity: 31% (95 aa)

YILRQRIGEGAFSSVWLADCKDVSIPAAVKIISKSTLDQPDVFTRFQR--EISLLQQCSHPFITHFYELYEDTNRYYVFMEYAENG----DFESFLQ--T
| . ..||.|.|..|...  |. ..  |||||.|.  . ...  .  |  ||.... ..||.|  .|. .|| ...|. |||.|.|    |  ....   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

RGRL--PENMSRFFFAQLITALDYLHNTCRIAHRDLKPQNILLDRYNNI----RITDFGLSKAF-NDVVPNLTSNCGSPAYAAPEVII-GKPYNKAADVW
.|..  .|.  .|.. |.. .|.|.|. ..| ||||||.|||.|. ..|    .|.||||.| | .   . .|. ||.| |.|||||  |..| ...|.|
HGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGVILYQMATGHLPFQSP------DVKTVLMKIVS----FDPPYPPTMS-----------------SQLIDLLRRMLCRNPSKRITIKEIMEHPWV
|.|.|||.|..|..||..       | . .. .| .    || |.. ..|                 . ..|.....||..|.||.|...|..|||.
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 85699.m00080.AA MARK 13-266 36 7e-83 270.77 In-house 1-262 (262) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-262/262
Sequence Identity: 36% (97 aa)

YILRQRIGEGAFSSVWLADCKDVSIPAAVKIISKSTLDQPDVFTRFQREISLLQQCSHPFITHFYELYE--DTNR-YYVFMEYAENGDFESFLQTR--GR
| . . ||.|... | ||  |   .  |.||. |  |. |  .  ..|||..... .|| |. ...  |  ....  |. ||||..|.  .... .  ||
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LPENMSRFFFAQLITALDYLHNTCRIAHRDLKPQNILLDRYN--NIRITDFGLSKAFNDVVPNLTSNCGSPAYAAPEVIIGKPYN-KAADVWSLGVILYQ
|.|.  | .| |.. |. |.|.   |.|||.||.|||.|  .  || |.|||.|  ..     |.. ||.|.|.|||.. .|||. ...|.|||||.|| 
LHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIP-PGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYF

MATGHLPFQ--SPDVKTVLMKIVSFDPPYPPTMSSQLIDLLRRMLCRNPSKRITIKEIMEHPWV
| .|..||   . | |.   ||.. ....|. .| .. .|..|.|  ||..|.||.|||.|||.
MVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 85699.m00080.AA ULK 13-266 26 5.6e-82 278.66 In-house 1-324 (324) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-324/324
Sequence Identity: 26% (86 aa)

YILRQRIGEGAFS-SVWLADCKDV---SIPAAVKIISKSTLDQ-PDV------FTRFQREISLLQQCS---HPF--ITHFYELYEDT--NRYYVFMEYAE
|.|....|.|.|   |  . .|.        |.|.|.|. . . .           ...||.....     ||.  |  .|. .|..  | .| .||| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGDFESFLQTR---------GRLPENMSRFFFAQLITALDYLHNTCRIAHRDLKPQNILLDRYNN------------IRITDFGLSKAFN---DVVPNLT
 ||.|......         .||.|.  . || |.. .. .||.   | |||.||||||.   .             . |.|||..| ..        ..
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKH-NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

SNC------GSPAYAAPEVII----GKPYN-KAADVWSLGVILYQMATGHLPFQSPDVKTVL----------------MKIVSFDPP---YPPTMSSQLI
. .      |.| | ||...     .|||. . .|.||||.|.|.| .|  ||.|.   .                  .|   ...|   . |  |....
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

DLLRRMLCRNPSKRITIKEIMEHPWV
||.||||......||.. || .|||.
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 85699.m00080.AA ULK 13-266 25 1.4e-78 267.32 In-house 1-329 (329) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-329/329
Sequence Identity: 25% (85 aa)

YILRQRIGEGAFSSVWLADCKDV----SIPAAVKIISKSTLDQPDVFTR-------FQREISLLQQCS--------HPFITHFYELYEDT--NRYYVFME
|.|....|.|.|  |  . .|.      .  |.|.|.|....|             ...|| ....          || |  .|. .|..  | .| .||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YAENGDFESFLQTRGRLPENM----------SRFFFAQLITALDYLHNTCRIAHRDLKPQNILLDRYNN------------IRITDFGLSKAFNDV---V
| . ||.|........|||.            . || |.. .. .||   .| |||.||||||..  .             . |.|||..| ...     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKH-NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

PNLTSNC------GSPAYAAPEVII----GKPYN-KAADVWSLGVILYQMATGHLPFQSPDVKTVL----MKIVS-----------FDPPYP-----PTM
  ...        |.| | ||...     .|||. . .|.||||.|.|.| .|  ||...   .      .| .            . . .|     |. 
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

SSQLIDLLRRMLCRNPSKRITIKEIMEHPWV
|....||.||||......||.. |. .|||.
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 85699.m00080.AA Ciliate-E2-Unclassified 13-266 24 1.9e-78 266.92 In-house 1-352 (352) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-352/352
Sequence Identity: 24% (88 aa)

YILRQRIGEGAFSSVWLADCKDVSIPA-----AVKIISKSTLDQPDVFTRFQREISLLQQ-------------------CSHPFITHFYELYEDTNRYYV
|.. . ||.|.|..|... .|.    .     . ||.... . .  .  .. .|.  ...                   . |||| ....  .|..  | 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

FMEYAENGDFESFLQTR-----------------GRLPENMSR-----FFFAQLITALDYLHNTCRIAHRDLKPQNILLDRYN---NIRITDFGLSKAFN
 |||.|.|| . ... |                  ...|. ..     |.|||.. .|.|||    | |||.||.|||.|  .   .|.|.|||.||  .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

DV---------------VPNLTSNCGSPAYA----APEVIIGKPYN----KAADVWSLGVILYQMATGHLPFQSPDVKT----------------VLMKI
.                  .....||.| |     ||||. |. |.    ...|.||||||||.| .| .||.... .                 .. .|
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

VSFDPPYPP--------TMSSQLIDLLR----RMLCRNPSKRITIKEIMEHPWV
   .. .|.        . | . .|...    .||  ||.||||...|..||| 
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 85699.m00080.AA Ciliate-E2 13-266 25 6.3e-77 261.87 In-house 1-365 (365) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-365/365
Sequence Identity: 25% (94 aa)

YILRQRIGEGAFSSVWLADCKDVSI------------------PAAVKIISKSTLDQPDVFTRFQ-----REIS----------LLQQCSHPFITHFYEL
|.. . ||.|.|.||...  . |                     ...||. . .. . ...  .|     |||           .|.| .||.|  .|| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YE--DTNRYYVFMEYAENGDFESFLQTR-----------GRLPENMSRFFFAQLIT---------------ALDYLHNTCRIAHRDLKPQNILLDRYNNI
..  |.| .|  |||.. || ..... .           ... |.  .....|..                || |||.  .| |||.||.|||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RITDFGLSKAFNDV-----------------VPNLTSN--------------CGSPAYAAPEVIIGKP---------YNKAADVWSLGVILYQMATGHLP
 |.|||||| ..|                    . |.               ||.| | |||.. ||.         |....|.||||||||.| .| .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FQSPDVKTVLMKIVSFDPP--------------YPPTMSSQLIDLLRR----MLCRNPSKRIT-IKEIMEHPWV
|     .  . . ..|..|               .   | . .||...    ||...|.|||| ...|..||| 
F----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 85699.m00080.AA QIK 13-266 35 7.6e-74 251.64 In-house 1-272 (272) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-272/272
Sequence Identity: 35% (97 aa)

YILRQRIGEGAFSSVWLADCKDVSIPAAVKIISKSTLDQPDVFTRFQREISLLQQCSHPFITHFYELYEDTNRYYVFMEYAENGDFESFLQTRGR-----
| . . || | |  | ||  .      |.||| || ||. . ...  ||. .. . .||.|.  |.  |  .  |. .||..||.    |   ||     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDE-ENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LPENMSRFFFAQLITALDYLHNTCRIAHRDLKPQNILLDRYNNIRITDFGLSKAFNDVVPNLTSNCGSPAYAAPEVIIGKPYN-K
               ..||  |. | |...| .|.|.   |.|||||  |||||   || | |||.|  |    . | . ||||.|||||.  || |.  
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKR-NIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQL-LMTWCGSPPYAAPEMFEGKEYDGP

AADVWSLGVILYQMATGHLPFQSPDVKTVLMKIVSFDPPYPPTMSSQLIDLLRRMLCRNPSKRITIKEIMEHPWV
 .|.||.||.|| . .| ||| .. ...   ...|     |. ||. . .| |.||  .|..|.||. |..|.| 
KVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 85699.m00080.AA Pkinase_Tyr 13-161 27 3.9e-18 62.06 Pfam 1-160 (270) Show / Hide 
Range on Protein: 13-161
Range on HMM: 1-160/270
Sequence Identity: 27% (44 aa)

YILRQRIGEGAFSSVWLADCK----DVSIPAAVKIISKSTLDQPD-VFTRFQREISLLQQC-SHPFITHFYELYE-DTNR--YYVFMEYAENGDFESFLQ
 .. . .||||| .|... .|    .  || |||.. | . ....     | ||.... |  .|| |  .|     .     .|. |||...||  ..|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

T----RGRLPENMSRFFFAQLITALDYLHNTCRIAHRDLKPQNILLDRYNNIRITDFGLSKA
.    ...|.  .   . .|   ...||..   . ||||   |.|... | ..|.||||...
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN-CIHRDLAARNCLVTENNVVKICDFGLARD
Kinase 85699.m00080.AA TyrKc 13-264 23 1.5e-16 44.68 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-264
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YILRQRIGEGAFSSVWLADCKDVSIPAAVKIISKSTLDQPDVFTRFQREISLLQQC--SHPFITHFYELYEDT-------NRYYVFMEYAENGDFESFLQ
  | . .|||||  |...  |   |. ||| . ...         | ||.... .   .|| |  .|    .          ... |||...||  ..|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

TRGR-LPENMSRFFFAQLITALDYLHNTCRIAHRDLKPQNILLDRYNNIRITDFGLSKAFNDV------VPNLTS----NCG--SP-AYAAPEVIIGKPY
 ... |.      |  |     .|||   .. ||||   |.|... . ..|.|||||..  |           ..    ..    |    |||.|  . .
KHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

NKAADVWSLGVILYQMAT-GHLPFQS-----PDVKTVLMKIVSF-DPPYPPT--------MSSQLIDLLRRMLCRNPSKRITIKEIMEHP
. . |||| || .. . | |  |         . . |. .. .   .| ||         ... . .. ..   ..|..| | .|| |  
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 85699.m00080.AA Pkinase_Tyr 180-203 41 0.743362 3.52 Pfam 182-205 (270) Show / Hide 
Range on Protein: 180-203
Range on HMM: 182-205/270
Sequence Identity: 41% (10 aa)

APEVIIGKPYNKAADVWSLGVILY
|||.|  . .. . |||| || ..
APECINYGKFTTKSDVWSFGVLMW