Gene 85593.m00049 (T.vaginalis)

85593.m00049

Species: T.vaginalis
Alias: TvagK0178, 85593.m00049
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
85593.m00049.AA Protein None 340 None Fasta, JSON
85593.m00049.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 85593.m00049.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 85593.m00049.AA S_TKc 12-263 27 3.9e-72 246.87 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-231/231
Sequence Identity: 27% (75 aa)

YIFKKAIGKGGFSTVYLVESEVYHQNYVAKVTPIDLEKPHTGDVDPLDAEIKALMNLSHQNIIRLYDHFTEGNNFFVILEYCQL--GSLQDSVGEDG---
| . . ||||.|..||..     .. .  |. .           . .  ||. |..  | ||..|||.| . .......|||    |.| |   . |   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LTLQQFICYGRQILSALAFVHSKNIAHRDIKPGNILVDSMGRIKLSDFGISILGANNVVSTFSGSFLYEAPEVILKKPHNPIQADIWSLGVLFAYL
    ..  .  .| .||..||.. ||..| |||.|| |||.|.  .||..|||.. .      .|| |.  | ||||.   ....  .|.||.|.... .
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

INGTTPWRSDNINVLKNRICTATFKLRSNTPPEVAELITSMLNIEPNERPTAQEILE-------MRLF
. | .|..  ..... ..|.          .||. ..|  .|. .|..|||| |.|.       .  |
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 85593.m00049.AA CAMKL 12-263 28 1.3e-68 218.02 In-house 1-297 (297) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-297/297
Sequence Identity: 28% (85 aa)

YIFKKAIGKGGFSTVYLVESEVY-HQNYVAKVTPIDLEK--PHTGDVDP---------LDAEIKALMNLS---HQNIIRLYDHFTEGNN------FFVIL
|.. | .|||.|..| | . . .  . .  |.  ..  .  |.. . ..         .  ||. .. |.   |.|||.||....  ..      .. ..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCQLGS--LQDSV---GEDG--LTLQQFICYGRQILSALAFVHSKNIAHRDIKPGNILVDSMG--RIKLSDFGIS-----I-LGANNVVSTFSGSFLYE
|||. |.  |.| .   |. .  ..  .   | |||.||... ||..|.|||||| |||.|. |   ||..||| |     .  | ..  .|| ||  | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVILK--KPHNPIQADIWSLGVLFAYLINGTTPWRSD--------NINVLKNRICTATFKLR--SNTPPEVAELITSMLNIEPNERPTAQEILEMRLF
|||....  ||..  ..||||.||.   .. |. |.. |        ||  |...| .  .. .  .  . ..  || .||.  |..|||...|.. . .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Pkinase 85593.m00049.AA Pkinase 12-263 26 1.2e-64 225.86 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-293/293
Sequence Identity: 26% (80 aa)

YIFKKAIGKGGFSTVYLVESEVYHQNYVAKVTPIDLEKP-------HTGDVDPLDAEIKALMNLSHQNIIRLYDHFTEGNNFFVILEYCQLG----SLQD
| ... ||.|.|..||.     . . .. |. . . ||.       ..       .||. . .|.| ||.|||| |.....  ...|||. |    .| |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFD

SVG---EDGL--TLQQFICYGRQILSALAFVHSKNIAHRDIKPGNILVDSMGRI----KLSDFGISIL--GANNVVSTFSGSFLYEAPEVILKKPHNPIQ
 .    . ..  . .. ..| .|||..|.. ||..| |||.|| |||.|. | |    |..|||.. .    ||. .|| |.  | |||||.. .. .  
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPK

ADIWSLGVLFAYLINGTTPWRSD------NINVLKNRICTATFKLRSNTP---------------------PEVAELITSMLNIEPNERPTAQEILEMRL
.|.||.|........| .|....      . ... .||  . ..  . ..                     .|  ..|...|.  |..||||..||.   
VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

F
|
F
Kinase 85593.m00049.AA CAMK 17-263 18 4.6e-62 198.47 In-house 1-425 (425) Show / Hide 
Range on Protein: 17-263
Range on HMM: 1-425/425
Sequence Identity: 18% (80 aa)

AIGKGGFSTVYLVESEVYH------------QNYVAKVTPID---------------LEKPHTG---------DVDPLDAEIKALMNLS-------HQNI
 .|.|.|..|.|..                 | . .|. . .               ..|  ..         | . .  ||. ...|.       | ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLYDHFTEGNN-------------------FFVIL---EYCQLGSLQDS-------VGE-------------DGLTLQQFICYGRQILSALAFVHSKNI
|.||...  ...                   .. ..   |||. | | |         |                .| ..   | |||.||... ||.||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDIKPGNILVDSM-----------------GRIKLSDFGIS--ILGA-----------------------NNVVSTFSGSFLYEA-PEVILK------
.|||.|| |||.|.                  . ||..||| .  . .                        .   .|| |.  | | |||...      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------KPHNPIQADIWSLGVLFAYLINGTTPWRSD-------------NINVLKNRICTATFKLRSNTPP------------------------EVAE
       ||  . ..|.||.||.   .  |. |...|             |.. |. .|... .   .   .                        |.  
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LITSMLNIEPNERPTAQEILEMRLF
|| .||. .|..|.|....|.   .
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 85593.m00049.AA Ciliate-E2-Unclassified 12-263 24 2e-56 193.77 In-house 1-352 (352) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-352/352
Sequence Identity: 24% (88 aa)

YIFKKAIGKGGFSTVYLVES----EVYHQNYVAKVTPIDLEKPHTGDVDPLDAEIKALMNLS-------------------HQNIIRLYDHFTEGNNFFV
|.. | ||.|||..||...     ..|.. |  |.  ..  .  . | . .  |.|...|..                   | .|......|.  .|.. 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-E-IMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

ILEYCQLGSLQDSVGEDG------------------LTLQQFI-----CYGRQILSALAFVHSKN-IAHRDIKPGNILVDSMG---RIKLSDFGISI-LG
..|||. |.|..   . .                  .| || .      | .|||..| . |.|| | |||||| |||.|. |   .||..|||||. ..
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

AN----------------NVVSTFSGSFLYE----APEVILKKPHNP---IQADIWSLGVLFAYLINGTTPWRSDNINV----------------LKNRI
 |                .  .||.|.  |     ||||. .. ..    ...|||||||.. ... |. |  . | .                 |.. |
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

CTATFKLRS--------NTPPEVAELIT----SMLNIEPNERPTAQEILEMRLF
.   .. ..        . .||....|.    .||.  ||.|.|...||.  .|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 85593.m00049.AA ULK 12-263 25 8.8e-56 191.64 In-house 1-324 (324) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-324/324
Sequence Identity: 25% (83 aa)

YIFKKAIGKGGFS-TVYLVESEVYH---QNYVAKVTPIDLEKPHTGDVD------PLDAEIKALMNLS---HQN--IIRLYDHFTEG--NNFFVILEYCQ
|. .. .||| |  .||  . .  .   | . .|. ...  .    . .       |. ||. .  |    |.|  |..||| | .   ||.. |.|||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

LGSLQDSVGEDG----------LTLQQFICYGRQILSALAFVHSKNIAHRDIKPGNILVDS------------MGRIKLSDFGISIL-GAN----NVVST
 | |..   ...          |. |. | . .||.... . |..|| |||||| |||.               |..|..||| .     |    ..  |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

FS------GSFLYEAPEVIL----KKPHNPIQADIWSLGVLFAYLINGTTP---W-RSDN--INVLKNR-------ICTATFKLR---SNTP--PEVAEL
.       |. || ||...     .||.. . .||||||..| ... | .|   | ....  |  |.|        |..  .. .   .. .  ||. .|
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

ITSMLNIEPNERPTAQEILEMRLF
|  || .....| . .||... .|
IRRMLQYDEKDRISWEEIFNHPWF
Kinase 85593.m00049.AA ULK 12-263 24 1.9e-55 190.54 In-house 1-329 (329) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-329/329
Sequence Identity: 24% (82 aa)

YIFKKAIGKGGFSTVYLVESEVYH----QNYVAKVTPIDLEKPHTGDVD------PLDAEIKALMNLS--------HQNIIRLYDHFTEG--NNFFVILE
|. .. .||| | .||  . .  .    . ...|. ... ..    . .       |. ||| .  |         |.||..||| | .   ||.. |.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCQLGSLQDSVGEDG-----------LTLQQFICYGRQILSALAFVHSKNIAHRDIKPGNILVDSM------------GRIKLSDFGISIL-GAN----N
||. | |..   ...           |. |. | . .|||... . |..|| |||||| |||..              |..|..||| .     .    .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

VVSTFS------GSFLYEAPEVIL----KKPHNPIQADIWSLGVLFAYLINGTTP---W-RSDN---INVLKNR-------ICTATFKLR-----SNTPP
.  |..      |. || ||...     .||..   .||||||..| ... | .|   | ....   |. |.|        |..  .. .      .  |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

EVAELITSMLNIEPNERPTAQEILEMRLF
|. .||  || .....| . .|.... .|
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 85593.m00049.AA AGC 12-263 20 7.3e-55 139.21 In-house 1-395 (395) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-395/395
Sequence Identity: 20% (81 aa)

YIFKKAIGKGGFSTVYLVESE------VYHQNYVAKVTPIDL--------EKPHT---------GDVDPLDAEIKALMNLS----------HQNIIR-LY
. |.| ||||.|..||||.           . |  ||   .         .  ||         |.   . .| . |....          |..|.. |.
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGY---VWEERNILEKCNHTHNHPIKSHHPFIVKILH

DHFTEGNN--FFVILEYCQ-----------LGSLQDSV---GEDGLTLQQFICYGRQ-------ILSALAFVHS-KNIAHRD-IKPGNILVDSMGRIKLS
  |   ..   . ..||..           . ...      .|  .. ..   |  .       |..|| . || ..| ||| .|| ||| |. | |||.
YSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLT

DFGISILGAN----------------------------------------------------NVVSTFSG--SFLYEAPEVILKKPHNPIQADIWS--LG
||| .  | |                                                    .  .|| |  .  | |||..    ... ..|.||  ||
DFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGK-ACDWWSFGLG

VLFAYLINGTTPWRSDN----------INVLKNRIC------TATFKLR----------SNTPPEVAELITSMLNIEPNERPT----------AQEILEM
.|.  .. | .| ..||           . . ..|.      .   |.           ..  ||   ||. .|. .|..|..          |.|| . 
CLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNH

RLF
  |
PWF
Kinase 85593.m00049.AA Ciliate-E2 12-263 23 1.9e-53 181.85 In-house 1-365 (365) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-365/365
Sequence Identity: 23% (87 aa)

YIFKKAIGKGGFSTVYLV-ESEVYHQ---------------------NYVAKVTPIDLEKPHTGDVDPLDAEIK----------ALMNLSHQNIIRLYDH
|.| | ||.|.|..||..   .| .|                     ...|. . .  .. ..  .. .  ||.           | .|.| |||..|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FT--EGNNFFVILEYCQLGSLQD--------------SVGEDGLTLQQFICYGRQILS---------------ALAFVHSKN-IAHRDIKPGNILVDSMG
|     ||.. ..|||| |.|.|              . .   .|... . . .|||.               || . |||| | |||||| |||.    
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

RIKLSDFGISI------------LGAN---------------------NVVSTFSGSFLYEAPEVILKKP--------HNPIQADIWSLGVLFAYLINGT
 ||..|||.|              ...                     |.. |. |.  | |||.. .|.        .   ..|||||||.. ... | 
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

TPWRSDNINVLKNRICTATFK----------------LRSNTPPEVAELITS----MLNIEPNERPT-AQEILEMRLF
.|.        ..  |   |                    . ..|.  ||      ||. .|..|.| ...||.   |
PPF------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 85593.m00049.AA MELK 12-263 31 5.9e-46 154.87 In-house 1-254 (254) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-254/254
Sequence Identity: 31% (82 aa)

YIFKKAIGKGGFSTVYLVESEVYHQNYVAKVTPIDLEKPHTGDVDPLDAEIKALMNLSHQNIIRLYDHFTEGNNFFVILEYCQLGSLQDS-VGEDGLTLQ
|   . || |||. | |    .  |    |.  .|  .    |.  . .|. || ||.||.| .||      . .|...|||  | . |  . .| |  .
YEVHDEIGTGGFAKVKLACHILTNQMVAIKI--MD-KNQLGHDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEE

QFICYGRQILSALAFVHSKNIAHRDIKPGNILVDSMGRIKLSDFGISILGANNV----VSTFSGSFLYEAPEVILKKPHNPIQADIWSLGVLFAYLINGT
.   . |||.||.|.|||.  ||||.|| |.|.|   ..|| |||.      ..    . |  ||  | |||.|  |      ||.||.|.|   |. | 
ETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGF

TPWRSDNINVLKNRICTATFKLRSNTPPEVAELITSMLNIEPNERPTAQEILEMRLF
 |.  ||. ..  .|    ..      ||  .|.  || ..|. |   ...|.    
LPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 85593.m00049.AA STE 12-263 21 2.1e-45 157.18 In-house 1-359 (359) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-359/359
Sequence Identity: 21% (79 aa)

YIFKKAIGKGGFSTVYLV---------ESEVY------HQNYVAKVTPID-------------LEKPHTGDVDPLDAEIKALMNLS--HQNIIRLYDHFT
. . . ||||.| |||.          ..         .. .  |. ...             ||. .. ... .  ||| .....  |.||.. |... 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EG-------NNFFVILEYCQLGSLQDSVG---EDGLT------------LQQFICYGRQILSA-LAFVHSKNIAHRDIKPGNILVDSMGRIKLSDFGISI
 .       .. ....||.  ||| | .    . | .             .| ... |||| . |.. ||..| ||||||.|||.     .||.|||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

LGANN------------------VVSTFSGSFLYEAPEVILK------KPHNPIQADIWSLGVLFAYLINGTTPWRS-DNI----NVLKNRICTA-----
  ...                     || |.  . |||||..      |... ...|||||| .   ...|  ||    .     . ..| .. .     
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

------TFKLRSNTP-------------------PEVAELITSMLNIEPNERPTAQEILE--MRLF
        .| ...                    ||  . |   |...||.||||.. |.     .
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 85593.m00049.AA MARK 117-263 40 5.5e-44 141.78 In-house 111-262 (262) Show / Hide 
Range on Protein: 117-263
Range on HMM: 111-262/262
Sequence Identity: 40% (62 aa)

RQILSALAFVHSKNIAHRDIKPGNILVDSMG--RIKLSDFGISILGANNV-VSTFSGSFLYEAPEVILKKPHNPIQADIWSLGVLFAYLINGTTPWRSDN
|||.||. . |||||.|||||| |||.|. |   ||..||| ||   ..   .|| |.  | |||..|||| .   .|||||||.  ... |. |.. |.
RQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDT

--INVLKNRICTATFKLRSNTPPEVAELITSMLNIEPNERPTAQEILEMRLF
  .. |. .| .  ..  .. ..|   || ..|.. |.||||..||.. . .
QDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 85593.m00049.AA TyrKc 12-263 21 1.2e-14 14.1 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-263
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

YIFKKAIGKGGFSTVYLVESEVYHQNYVAKVTPIDLEKPHTGDVDPLDAEIKALMNL--SHQNIIRLYDHFTEG-------NNFFVILEYCQLGSLQDSV
  ..| .| | | .||. .     ..   |.   |        .  .  |.. ...|  .|.||.|||   |..          ....||. .|.|.|  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

GEDG--LTLQQFICYGRQILSALAFVHSKNIAHRDIKPGNILVDSMGRIKLSDFGISILGANN-VV----STFSGSF--LYE--------APEVILKKPH
 . .  |...... .  || .  .. ||||. |||.   |.||.. ...| |||| |  . .        .. . .              |||.| ..  
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

NPIQADIWSLGVL----FAYLINGTTPWRS-----DNINVLKNRICTATFKLRSNT---------PPEVAELITSMLNIEPNERPTAQEILEMRLF
. .. |.|| ||.    | |   | .|.        .   . ... .     .            |.|. .....  . .|..||| .||   ..|
T-TKSDVWSFGVCMWEIFTY---GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 85593.m00049.AA MARK 12-100 25 1.3e-14 44.31 In-house 1-91 (262) Show / Hide 
Range on Protein: 12-100
Range on HMM: 1-91/262
Sequence Identity: 25% (24 aa)

YIFKKAIGKGGFSTVYLVESEVYHQNYVAKVTP-IDLEKPHTGDVDPLDAEIKALMNLSHQNIIRLYDHFT--EGNN-FFVILEYCQLGSLQD
| ..| ||.|....|.|. .  .....  |. .  .| .|..    ..  ||. .. |.| |||.|.. .   . .. ...|.||.  |.| |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQW--MKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYD
Kinase 85593.m00049.AA Pkinase_Tyr 61-159 30 4.6e-14 48.24 Pfam 53-160 (270) Show / Hide 
Range on Protein: 61-159
Range on HMM: 53-160/270
Sequence Identity: 30% (33 aa)

EIKALMNL-SHQNIIRLYDHFT-EGNN--FFVILEYCQLGSLQDSVGED-----GLTLQQFICYGRQILSALAFVHSKNIAHRDIKPGNILVDSMGRIKL
|.| ...| .|.||.|||   | .|     ....||...|.| |   .       ||... ... .|| ..... .|||. |||.   |.||.. . .| 
EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKI

SDFGISIL
.||| . .
CDFGLARD
Kinase 85593.m00049.AA Pkinase_Tyr 231-262 34 0.153529 5.84 Pfam 240-270 (270) Show / Hide 
Range on Protein: 231-262
Range on HMM: 240-270/270
Sequence Identity: 34% (11 aa)

NTPPEVAELITSMLNIEPNERPTAQEILEMRL
|.|.|. .|...  . .|..||| .||   .|
NCPDEIYDLMKQCWHYDPEDRPTFSEI-HEQL