Gene 85144.m00127 (T.vaginalis)

85144.m00127

Species: T.vaginalis
Alias: TvagK0043, 85144.m00127
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
85144.m00127.AA Protein None 380 None Fasta, JSON
85144.m00127.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 85144.m00127.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85144.m00127.AA CAMK 13-261 23 1.1e-105 341.57 In-house 1-425 (425) Show / Hide 
Range on Protein: 13-261
Range on HMM: 1-425/425
Sequence Identity: 23% (99 aa)

PIGVGGFSKVFRATHKKTG------------VNVAIKMIPKK-INND-----------------------DSDYEEKIQKEIEIMKI-------VKHPFI
 .| |.|.||....||.|.            . ||||.|.|| . ..                       .   ......||||||        ..|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VELFEIVET-------------------EDEYFLIM---DYASQG----SILNNINER---------------GAFSEDEASIIFAQIILVIKHLQQTCH
. |.|. |.                   .......|   .|.| |     ... | |.               | |.|.||. .| ||.  .... .   
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-

IAHRDIKAENVLLDEN-----------------RNIRVIDFGLS--CLNLN----------------------GEMMKTQCGSPPYAS-PELILGWQ---
|.|||.| ||.|||.|                  || .||||..  .   .                      |..|||.||.|.|.. ||...| .   
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------YTFASDIWSCGILLYIMVCKSMSFYDE-------------NLSSLANKILFAEVEYPES------------------------LSPCLV
           |....|.||||..||||.|  . ||..             |.. |  ||. .. ..|..                        .|.   
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLLQKMLTKNPQNRISLDEILAHPWL
||..|||...|..|......|.|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 85144.m00127.AA CAMKL 9-261 36 2.7e-102 327.25 In-house 1-297 (297) Show / Hide 
Range on Protein: 9-261
Range on HMM: 1-297/297
Sequence Identity: 36% (109 aa)

GNIIP-IGVGGFSKVFRATH-KKTGVNVAIKMIPKKINNDDSDYEEK-----------IQKEIEIMKIVK---HPFIVELFEIVETEDE------YFLIM
 .|.. .| |.|.||  ||| . ||. ||||.| ||  ..|   . .           |..||.||| ..   || |. |.|..||..       ..|.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

DYASQGS--ILNNINERGA----FSEDEASIIFAQIILVIKHLQQTCHIAHRDIKAENVLLDENR--NIRVIDFGLSCL-----NLNGEMMKTQCGSPPY
 |.| |.   .. | ..|     ..|.||  .| ||.  .... . . |.|||||.||.|||||   || .||||.| .     . .|...||.||||||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

ASPELILG--WQYT-FASDIWSCGILLYIMVCKSMSFYDE--------NLSSLANKILFAEVEYP--ESLSPCLVDLLQKMLTKNPQNRISLDEILAHPW
..||...|   .|  .. ||||||..|| |||  . | |.        |   | .||     ..|   ..|  . ||..|||..||  |.....|. |||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

L
.
M
Kinase 85144.m00127.AA AGC 8-261 22 2.4e-96 248.97 In-house 1-395 (395) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-395/395
Sequence Identity: 22% (89 aa)

YGNIIPIGVGGFSKVFRATHK------KTGVNVAIKMIPK--KINNDDSDYEEKIQKE------------IEIMKIVK----------HPFIVE-LFEIV
.  . .|| |.|.||. . .|       ||   |.|.. |  ||  .. . .|... |             .|.. ..          |||||  |.   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ETEDE--YFLIMDYAS---------QG-SILNNIN---ERGAFSEDEASIIFAQ-------IILVIKHLQQTCHIAHRD-IKAENVLLDENRNIRVIDFG
...|    ...|.|..          |   .  .     .| |.|..| ...|.       |.| . .| .  .| ||| .| ||.||||. .|.  |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSCLNLNGE---------------------------------------------------MMKTQCG--SPPYASPELILGWQYTFASDIWS--CGILLY
|.. . |..                                                   . .| ||  .| | .|| .    |..| |.||   |.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

IMVCKSMSFYDENLS----------SLANKIL------FAEVEYP----------ESLSPCLVDLLQKMLTKNPQNRIS----------LDEILAHPWL
 |..    ||..|             . .||.      . .|..|          ...|| ..||..|.|.|.| .|.            .|| .||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 85144.m00127.AA AMPK 8-261 43 6.2e-95 282.28 In-house 1-254 (254) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-254/254
Sequence Identity: 43% (111 aa)

YGNIIPIGVGGFSKVFRATHKKTGVNVAIKMIPKKINNDDSDYEEKIQKEIEIMKIVKHPFIVELFEIV-ETEDEYFLIMDYASQGSILNNINERGAFSE
|     ||.| | ||  .||. ||  |||| . |.   |...  |.||.||.|.|...|| |. |.|.. ||... |..| |.| |     |  .|  .|
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDM-VERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQE

DEASIIFAQIILVIKHLQQTCHIAHRDIKAENVLLDENRNIRVIDFGLSCLNLNGEMMKTQCGSPPYASPELILGWQYT-FASDIWSCGILLYIMVCKSM
.||.  |.|||  .  . .   |.||| | ||.|||.| || . ||||| .   ||. || |||| ||.||.| |  |     ||||||. || |.|   
REACRFFQQIISGVEYCHR-HMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYL

SFYDENLSSLANKILFAEVEYPESLSPCLVDLLQKMLTKNPQNRISLDEILAHPWL
 | ||| ..|  ||.  |.. |. |||   ||...||...|..||. ..| .|||.
PFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
S_TKc 85144.m00127.AA S_TKc 8-261 32 6.9e-93 315.82 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-231/231
Sequence Identity: 32% (89 aa)

YGNIIPIGVGGFSKVFRATHKKTGVNVAIKMIPKKINNDDSDYEEKIQKEIEIMKIVKHPFIVELFEIVETEDEYFLIMDYASQ--GSILNNINERGA--
|  . .|| |.|.||....|||||  ||||.|.           |.|..||.|.|  .||.|| |... .. |.....|.|...  |. .  | .||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FSEDEASIIFAQIILVIKHLQQTCHIAHRDIKAENVLLDENRNIRVIDFGLSCLNLNGEMMKTQCGSPPYASPELILGWQYTF-ASDIWSCGILLY
    |.| .|  ...||.. .... .  .| |||.| ||.||||  .| ..||||...       .|.||.| | .||..   .|.. ..|.||||..||
LRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

IMVCKSMSFYDENLSSLANKILFAEVEYPESLSPCLVDLLQKMLTKNPQNRISLDEILA-------HPWL
.|.|    |.  ..  . .||.          || . |...|.|.|.|..|..  |.|.       |||.
EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 85144.m00127.AA MARK 8-261 40 1.7e-92 302.63 In-house 1-262 (262) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-262/262
Sequence Identity: 40% (107 aa)

YGNIIPIGVGGFSKVFRATHKKTGVNVAIKMIPKKINND-DSDYEEKIQKEIEIMKIVKHPFIVELFEIVE--TEDE-YFLIMDYASQGSILNNINER--
|  .  || |...||  |.||.||..||||...|.  ||  .   .... |||||| ..|| |..||...|  ||    .|||.||| |. .. | ..  
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQW--MKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPN

GAFSEDEASIIFAQIILVIKHLQQTCHIAHRDIKAENVLLDENR--NIRVIDFGLSCLNLNGEMMKTQCGSPPYASPELILGWQYT-FASDIWSCGILLY
|  .|.||  || ||.  .. . .   |.|||||.||.|.|||.  ||  ||||.|    .|.. .| ||.|||..||..|.  |. .. ||||.|..||
GRLHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLY

IMVCKSMSFYDEN--LSSLANKILFAEVEYPESLSPCLVDLLQKMLTKNPQNRISLDEILAHPWL
.||| .  | . .  .  |  |||  . ..|  .|. . .|.|..|| ||  |....||. |||.
FMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 85144.m00127.AA Pkinase 8-261 29 8.2e-80 276.25 Pfam 1-293 (293) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-293/293
Sequence Identity: 29% (87 aa)

YGNIIPIGVGGFSKVFRATHKKTGVNVAIKMIPKKINNDDSDYEEKIQK--EIEIMKIVKHPFIVELFEIVETEDEYFLIMDYASQG----SILNNIN--
|  . .|| |.|..|....||.||  ||.| |.|.  ...|. ..   .  ||.||| ..||.||.|....|..|.. ..|.|.  |    .    |   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

ERGAF--SEDEASIIFAQIILVIKHLQQTCHIAHRDIKAENVLLDENRNI----RVIDFGLSCL--NLNGEMMKTQCGSPPYASPELIL-GWQYTFASDI
..|.|  ||.|.  .. ||.  .... . . | |||.| ||.|.|.| .|    ...||||...  . |.. |.| ||.|.|..||.|. |  |. ..|.
RHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSCGILLYIMVCKSMSFYDE------NLSSLANKILFAEVEYPESLS---------------------PCLVDLLQKMLTKNPQNRISLDEILAHPWL
||||..||.|.|.   |...      .   . ..|. ........ .                     . . |.. ..|.|.|. |.. ..|| |||.
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 85144.m00127.AA QIK 8-261 33 1.4e-76 260.77 In-house 1-272 (272) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-272/272
Sequence Identity: 33% (92 aa)

YGNIIPIGVGGFSKVFRATHKKTGVNVAIKMIPKKINNDDSDYEEKIQKEIEIMKIVKHPFIVELFEIVETEDEYFLIMDYASQGSILNNINERGA----
|     || | |  | .|.|. |   |||| | |     |... .|.  |..|||  .||.|. |... ||.|  .....|.|.| .   ... |     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQL--DEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVK

----------------FSEDEASIIFAQIILVIKHLQQTCHIAHRDIKAENVLLDENRNIRVIDFGLSCLNLNGEMMKTQCGSPPYASPELILGWQYT-F
                 .|.||  .| ||.. .... .  .|.|||.||||.|||.| || ..|||.| .  .|....| ||||||| ||. .| .|.  
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKR-NIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGP

ASDIWSCGILLYIMVCKSMSFYDENLSSLANKILFAEVEYPESLSPCLVDLLQKMLTKNPQNRISLDEILAHPWL
 .|||| |..||..|| .. |  ..| .| ...|   .  | ..|  . .|  .||. .|. |.. . |. |.|.
KVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 85144.m00127.AA Ciliate-E2 8-261 22 1.4e-71 244.1 In-house 1-365 (365) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-365/365
Sequence Identity: 22% (85 aa)

YGNIIPIGVGGFSKVFRATHKKTGVN------------------VAIKMIPKKINNDD----SDYEEKIQKEIE----------IMKIVKHPFIVELFEI
|  |  || |.|..|......|.. .                  |.||.. .||.. .       |..| .||.          |.....||.|....| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VE--TEDEYFLIMDYASQGSILNNINER-----------GAFSEDEASIIFAQIIL---------------VIKHLQQTCHIAHRDIKAENVLLDENRNI
 .  ... ..|.|.|...|. .  |...           . |.| |.. |..||.                 ...| .  .| ||||| ||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RVIDFGL------------------SCLNLNG---------------EMMKTQCGSPPYASPELILGWQ---------YTFASDIWSCGILLYIMVCKSM
 .|||||                   ... ..               .| .|.||.|.| .|| . | .         |....||||.|..||.|...  
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

SFYDENLSSLANKILFAEVEYP------------------ESLSPCLVDLLQK----MLTKNPQNRIS-LDEILAHPWL
 |         ..|.  ....|                  ...|.   ||..|    || |.|..||.  ..|| |||.
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 85144.m00127.AA Ciliate-E2-Unclassified 8-261 26 4.3e-68 232.53 In-house 1-352 (352) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-352/352
Sequence Identity: 26% (95 aa)

YGNIIPIGVGGFSKVFRATHKKTGVNVAIKMIPKKINNDDSDYEEK---IQKEIEIMKI------------------VKHPFIVELFEIVETEDEYFLIM
|  |  || |||.||... |||..   |.|.. |......  ...|   .....|....                   .||||| .|.. ....  ...|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

DYASQGSILNNINERGA-----------------FSEDEAS-----IIFAQIILVIKHLQQTCHIAHRDIKAENVLLDENR---NIRVIDFGLSCLNLNG
.|. .|. .. |..|.                  |.| .|.      .||||.. ...| .  .| ||||| ||.|.|.|    .|..||||.|  . . 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

----------------EMMKTQCGSPPYA----SPELILGWQYT----FASDIWSCGILLYIMVCKSMSFYDENLSS----------------LANKILF
                .||.|.||.| |     .||.. | .|     ...||||.|..|| |.     |||.|  .                | ..|. 
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

AEVEYPE--------SLSPCLVDLLQ----KMLTKNPQNRISLDEILAHPWL
 ....|.         .||.  |...    ||| ||| .||....|| |||.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 85144.m00127.AA ULK 8-261 28 2.2e-67 230.2 In-house 1-324 (324) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-324/324
Sequence Identity: 28% (92 aa)

YGNIIPIGVGGFS-KVFRATHKKT---GVNVAIKMIPKK-INNDDSDYE-----EKIQKEIEIMKIVK---HPF--IVELFEIVETEDE--YFLIMDYAS
|  .  .| | |  ||.....|||   .. ||.|||.|| .|.. ...|     .....||.|||. |   ||.  ||.|... || ..  ...||.|  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

QGSILNNINERGA---------FSEDEASIIFAQIILVIKHLQQTCHIAHRDIKAENVLLDENRN------------IRVIDFGLSCLNLNG----EMMK
.|   . |....          .||.|| ..| ||.   |.|..   | ||||| .| |. ..              . . |||..    |.     |..
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKH-NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

TQC------GSPPYASPELIL----GWQYT-FASDIWSCGILLYIMVCKS-----MSFYDENLS--SLANK-------ILFAEVEYP-----ESLSPCLV
|..      |.| | .|...     . .|. . .|||| |...| |.  .     . |.|..|   .| |.       |    ...|       .|| . 
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

DLLQKMLTKNPQNRISLDEILAHPWL
||...||....  ||| .||..|||.
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 85144.m00127.AA ULK 8-261 27 4.2e-66 225.92 In-house 1-329 (329) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-329/329
Sequence Identity: 27% (90 aa)

YGNIIPIGVGGFSKVFRATHKKT----GVNVAIKMIPKK-INNDDSDYE-----EKIQKEIEIMKIVK--------HPFIVELFEIVETEDE--YFLIMD
|  .  .| | | ||.....|||    .. ||.|||.|. .|..  ..|     . ...||.|||  |        || ||.|... || ..  ...||.
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YASQGSILNNINERGA----------FSEDEASIIFAQIILVIKHLQQTCHIAHRDIKAENVLLDENRN------------IRVIDFGLSCLNLNG----
|  .|   . |....           .||.|| ..| ||.   |.|..   | ||||| .|.|....              . . |||..    |.    
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKH-NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

EMMKTQC------GSPPYASPELIL----GWQYT-FASDIWSCGILLYIMVCKS-----MSFYDEN---LSSLANK-------ILFAEVEYP-----ESL
.||.|.       |.| | .|...     . .|. . .|||| |...| |.        . |.|..   . .| |.       |     ..|       .
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

SPCLVDLLQKMLTKNPQNRISLDEILAHPWL
|| . ||...||....  ||| .|...|||.
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 85144.m00127.AA TyrKc 8-261 19 1.5e-15 28.65 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-261
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

YGNIIPIGVGGFSKVFRATHKKTGVNVAIKMIPKKINNDDSDYEEKIQKEIEIMKIV--KHPFIVELFEIVETE-------DEYFLIMDYASQGSILNNI
   .  .| | | .|...| |   ..||.||. .         .| . .|..||. .  .|| || |. .. ..       . ....| |.. |. .. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

-NERGAFSEDEASIIFAQIILVIKHLQQTCHIAHRDIKAENVLLDENRNIRVIDFGLSCLNLNG-------EMMKTQ---CGS--PPYA--SPELILGWQ
 . |. .. ..   .  ||     .| . . | |||. | |.|..||. ... |||||    ..       .. ...   .|    |.   .|| |    
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCI-HRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YTFASDIWSCGILLYIMVCKSMSFYDE------NLSSLANKILFAEVEYPESL---------SPCLVDLLQKMLTKNPQNRISLDEILAHPWL
.|..||.|| |.... .    .. | .      . . . ...   .   .            .. . .. ..    .| .| .  ||  |  .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 85144.m00127.AA Pkinase_Tyr 8-96 26 1.5e-09 32.99 Pfam 1-96 (270) Show / Hide 
Range on Protein: 8-96
Range on HMM: 1-96/270
Sequence Identity: 26% (26 aa)

YGNIIPIGVGGFSKVFRATHK----KTGVNVAIKMIPKKINNDDSD-YEEKIQKEIEIMKIV-KHPFIVELFEIVE-TEDE--YFLIMDYASQGSILN
   .  .| | | .|...| |    .|.. ||.||.  | . .... . |.  .|..|||   .|| || |  ..   ..   ....| |.  |. |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD
Kinase 85144.m00127.AA Pkinase_Tyr 131-198 31 2.8e-05 18.51 Pfam 134-205 (270) Show / Hide 
Range on Protein: 131-198
Range on HMM: 134-205/270
Sequence Identity: 31% (23 aa)

HRDIKAENVLLDENRNIRVIDFGLSCLNLNGEMM-KTQC---GSPPYASPELILGWQYTFASDIWSCGILLY
|||. | |.|..||. ... ||||. .  | .   ...       .  .|| |    .| .||.|| |.|..
HRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMW