91798.m00159

Species: T.vaginalis
Alias: 91798.m00159, TvagK0212
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
91798.m00159.AA Protein None 339 None Fasta, JSON
91798.m00159.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 91798.m00159.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 91798.m00159.AA S_TKc 12-263 28 7e-74 252.67 SMART 1-231 (231) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-231/231
Sequence Identity: 28% (76 aa)

YGFKKLIGKGGFSFVYLVESEDDHKKYCAKVTPLNNDIILGVKIDPLEAEIKALMSLSHQNIIRLYDHFTENNCFFIILEYCQL--GSMQDTLNKKG---
| . ..||||.|. ||..   ......  |. .           . .. ||. |..  | ||..|||.| . .......|||    |.. | . |.|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LPKEQFINYARQIVSALTFVHSKNIAHRDIKPGNILIDSLGHIKLSDFGISITNANNMIEPFSGSLLYMPPEIILKKPHNPMQADIWSLGVLFAYM
    .|  .   |..||..|| . ||..| |||.|| |||.|.  |||..|||..          | |.. ||.||..   ....  .|.||.|.... |
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

INGRAPWQCDNVNSLRTCIIAGDFKLRANTPPEIIDLISKMMRIDPNERPSVAEILN-------YKLF
. |. |..  ... .   |           .|| .|.|.|... ||..||.. |.|.          |
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 91798.m00159.AA CAMKL 12-263 30 9.1e-71 225.02 In-house 1-297 (297) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-297/297
Sequence Identity: 30% (90 aa)

YGFKKLIGKGGFSFVYLVES-EDDHKKYCAKVTP----LNNDIILGV------KIDP-LEAEIKALMSLS---HQNIIRLYDHFTENNC------FFIIL
| . | .|||.|. | | .      .|.  |.       |.....        . |. .. ||. ...|.   |.|||.||....  ..      .....
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCQLGS--MQDTLNKKG-----LPKEQFINYARQIVSALTFVHSKNIAHRDIKPGNILIDSLG--HIKLSDFGIS-----I-TNANNMIEPFSGSLLYM
|||. |.  ..| . |.|     .| ..   | ||||||. . ||..|.|||||| |||.|. |   ||..||| |     .  . ... . | ||. ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPEIILK--KPHNPMQADIWSLGVLFAYMINGRAPWQCD--------NVNSLRTCIIAGDFKLRANTPP-EIIDLISKMMRIDPNERPSVAEILNYKLF
.|||...  ||..  ..||||.||.   |. |. |. .|        |.  |.  |. | .. .    . . .|||.||.  .|..||.. .|.| . .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase 91798.m00159.AA CAMK 17-263 18 1.1e-68 220.15 In-house 1-425 (425) Show / Hide
Range on Protein: 17-263
Range on HMM: 1-425/425
Sequence Identity: 18% (79 aa)

LIGKGGFSFVYLVESEDDH------------KKYCAKVTPLN---------------NDII---------LGVKIDPLEAEIKALMSLS-------HQNI
 .|.|.|. |.|..   .             .|. .|. . .                |..          ... . .. ||. ...|.       | ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLYDHFTE-------------------NNCFFIIL---EYCQLG----SMQDTLNKKG----------------LPKEQFINYARQIVSALTFVHSKNI
|.||...                     ........   |||. |     . | . ..|                .. ..   | |||.||. . ||.||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDIKPGNILIDSL-----------------GHIKLSDFGIS--ITNA-----------------------NNMIEPFSGSLLYMP-PEIILK------
.|||.|| |||.|.                  . ||..||| .  ..                         . . . | |.. ||. ||....      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------KPHNPMQADIWSLGVLFAYMINGRAPWQCD-------------NVNSLRTCIIAGDFKLRANTPP------------------------EIID
       ||  . ..|.||.||.   |  |. |.. |             | . |   |..|..       .                        | .|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LISKMMRIDPNERPSVAEILNYKLF
||.||.. ||..|......|| . .
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 91798.m00159.AA Ciliate-E2-Unclassified 12-263 24 9.7e-66 224.72 In-house 1-352 (352) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-352/352
Sequence Identity: 24% (85 aa)

YGFKKLIGKGGFSFVYLVESEDDHKKYCAKVTPLNNDIILGVKIDPLE----AEIKALMSLS-------------------HQNIIRLYDHFTENNCFFI
| . | ||.|||. ||... ...  .| |. . ..  .|  .|.   .     |.|......                   | .|......|.  ....|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKY-MKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

ILEYCQLGSMQDTLNK------------------KGLPKEQFI-----NYARQIVSALTFVHSKN-IAHRDIKPGNILIDSLG---HIKLSDFGISI---
..|||. |.... ..|                  | .. .| .     .|..||...| . |.|| | |||||| |||.|. |   .||..|||||.   
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

--------------TNANNMIEPFSGSLLYM----PPEIILKKPHNPM---QADIWSLGVLFAYMINGRAPWQCDNVNS----------------LRTCI
               . ..|.  |.|.. ||    .||.. .. .. .   ..|||||||.. .|. |. | .. | ..                |.  |
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

IAGDFKLRA--------NTPPEIIDLIS----KMMRIDPNERPSVAEILNYKLF
...... .         . .|| .|.|.    ||.  .||.|..  .|||  .|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 91798.m00159.AA ULK 12-263 26 1.1e-65 224.53 In-house 1-329 (329) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-329/329
Sequence Identity: 26% (87 aa)

YGFKKLIGKGGFSFVYLVESEDDH----KKYCAKVTPLNNDIILGVK------IDPLEAEIKALMSLS--------HQNIIRLYDHFTEN--NCFFIILE
|  .. .||| |  ||  . ....    .|. .|. ...  ..          .. |. ||| .  |         |.||..||| | .   |...||.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCQLGSMQDTLNKKG-----------LPKEQFINYARQIVSALTFVHSKNIAHRDIKPGNILIDSL------------GHIKLSDFGISITNANN-----
||. |  .. ..|..           |. .. |.. .||.... . |..|| |||||| ||||.              |..|..||| . .  |.     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

MIEPFS------GSLLYMPPEIIL----KKPHNPMQADIWSLGVLFAYMINGRAPWQCDNVNSLRTCIIAGDFK-------------LRAN-------TP
|.  ..      |. ||| |.|.     .||..   .||||||..| .|. |. |...   |..   ||   ..             |. .         
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PEIIDLISKMMRIDPNERPSVAEILNYKLF
||..|||..|. .|...| |  |..| ..|
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 91798.m00159.AA ULK 12-263 26 2.6e-65 223.27 In-house 1-324 (324) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-324/324
Sequence Identity: 26% (86 aa)

YGFKKLIGKGGFS-FVYLVESEDDH---KKYCAKVTPLNNDIILGVK------IDPLEAEIKALMSLS---HQN--IIRLYDHFTEN--NCFFIILEYCQ
|  .. .||| |   ||  . ....   ... .|. .... ..   .      .. |. ||. .  |    |.|  |..||| | .   | ..||.|||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

LGSMQDTLNKKG----------LPKEQFINYARQIVSALTFVHSKNIAHRDIKPGNILIDSL------------GHIKLSDFGISITNANNMIEPFS---
 |  .. ..|..          |. .. |.. .||.... . |..|| |||||| ||||               |..|..||| . .  ||. | .    
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GSLLYMPPEIIL----KKPHNPMQADIWSLGVLFAYMINGRAP---WQCDNVN----SLRTC-------IIAGDFKLR---ANTP--PEIID
        |. ||| |.|.     .||..   .||||||..| .|. |. |   |   . .    .|          |    .. .   .. .  ||..|
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LISKMMRIDPNERPSVAEILNYKLF
||..|. .|...| |  ||.| ..|
LIRRMLQYDEKDRISWEEIFNHPWF

Kinase 91798.m00159.AA AGC 12-263 22 6e-63 160.59 In-house 1-395 (395) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-395/395
Sequence Identity: 22% (88 aa)

YGFKKLIGKGGFSFVYLVESE------DDHKKYCAKVTPLNN-DIILGV-KIDPLEAE------------IKALMSLS----------HQNIIR-LYDHF
. |.|.||||.|. ||||.        |  | |  ||       .|.   ...   .|             . |. ..          |..|.. |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

TENNC--FFIILEYCQ--------LGS-MQDTLNKK-----GLPKEQFINYARQ-------IVSALTFVHS-KNIAHRD-IKPGNILIDSLGHIKLSDFG
  ..    ....||..         |  .  . ...      .. |.   || .       ||.|| . || ..| ||| .|| |||.|. |||||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

ISITNANNM----------------------------------------------------IEPFSG--SLLYMPPEIILKKPHNPMQADIWS--LGVLF
 .  . |..                                                       | |  .  ||.|||.    ...  .|.||  ||.|.
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKA-CDWWSFGLGCLM

AYMINGRAPWQCDNVN----------SLRTCIIAGD----FKLR------------ANTPPEIIDLISKMMRIDPNERPS----------VAEILNYKLF
  |. |. | . ||..           .   |. |.    .|..             .  ||  |||.|..  ||..|.           . || | . |
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF





Kinase 91798.m00159.AA Pkinase 12-263 26 1.1e-60 212.75 Pfam 1-293 (293) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-293/293
Sequence Identity: 26% (77 aa)

YGFKKLIGKGGFSFVYLVESEDDHKKYCAKVTPLNNDIILGVKIDPLEAEIKALMSLSHQNIIRLYDHFTENNCFFIILEYCQLG----SMQDTLN---K
| ... ||.|.|. ||.    .. |... |. .. ..     ... . .||. . .|.| ||.|||| |....   ...|||. |    .  | .    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KGL--PKEQFINYARQIVSALTFVHSKNIAHRDIKPGNILIDSLGHI----KLSDFGISI---TNANNMIEPFSGSLLYMPPEIILKKPHNPMQADIWSL
...  . .. ..|..||...| . ||..| |||.|| |||||. |||    |..|||..    .  |     | |.. ||.||.|.. .. .  .|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLFAYMINGRAPWQ-C----DNVNSLRTCIIAGDFKLRANTP-----------------------PEIIDLISKMMRIDPNERPSVAEILNYKLF
|.....|..|| |.. .    . .. .      .. .|. . |                       .| .|.|... . ||..||. ..||. . |
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 91798.m00159.AA MARK 12-263 32 7.3e-60 194.43 In-house 1-262 (262) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-262/262
Sequence Identity: 32% (88 aa)

YGFKKLIGKGGFSFVYLVESEDDHKKYCAKVTPLNNDIILG-VKIDPLEAEIKALMSLSHQNIIRLYDHFT--ENNC-FFIILEYCQLGSMQDTLNKK--
| ..| ||.|... |.|. .   ..|.. |. . ..  .    .. ... ||. ...|.| |||.|.. .   .... ...|.||.  |.. | . ..  
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFK--LNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPN

GLPKEQFINYAR----QIVSALTFVHSKNIAHRDIKPGNILIDSLG--HIKLSDFGISITNANNM-IEPFSGSLLYMPPEIILKKPHNPMQADIWSLGVL
|  .|   . ||    |||||. . |||||.|||||| |||||. |   ||..||| ||   ...  . | |.. ||.|||.|||| .   .|||||||.
GRLHE---EEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVV

FAYMINGRAPWQ--CDNVNSLRTCIIAGDFKLRANTPPEIIDLISKMMRIDPNERPSVAEILNYKLF
  .|. |. |.   . . . |.  | .|...   . ..|. .||.... ..|.|||.. ||.. . .
LYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 91798.m00159.AA Ciliate-E2 12-263 23 5.5e-59 201.11 In-house 1-365 (365) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-365/365
Sequence Identity: 23% (88 aa)

YGFKKLIGKGGFSFVYLVES-----------------------EDDHKKYCAKVTPLNNDIILGVKIDPLE---------AEIKALMSLSHQNIIRLYDH
| | |.||.|.|. ||...                        ... |.|  |.   |. ...  .|. .           | . | .|.| |||..|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FT--ENNCFFIILEYCQLGSMQDTLN---KKGLPK---------EQFINYARQIVS---------------ALTFVHSKN-IAHRDIKPGNILIDSLGHI
|    .|......|||| |...| ..   || . .         .. ... .||..               || . |||| | |||||| |||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLSDFGISI------------TNANNMIEPF----------------------SGSLLYMPPEIILKKP--------HNPMQADIWSLGVLFAYMINGRA
|..|||.|               ...... .                       |.. ||.|||. .|.        .   ..|||||||.. .|. |. 
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PWQCDNVNSLRTCIIAGDFKL--------------RANTPPEIIDLISK----MMRIDPNERPS-VAEILNYKLF
|.     .    | |  ...                 . ..| .|||.|    |.  ||..|..   .||| . |
PF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 91798.m00159.AA STE 12-263 21 1.3e-48 167.85 In-house 1-359 (359) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-359/359
Sequence Identity: 21% (77 aa)

YGFKKLIGKGGFSFVYLVESED---------------DHKKYCAKVTPLNN-------------DIILGVKIDPLEAEIKALMSLS--HQNIIRLYDHFT
. . . ||||.|  ||.    .                .. .  |. .|.|             ...   ... .. ||| .. ..  |.||.. |... 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EN-------NCFFIILEYCQLGSMQDTLN-KKGLPK-------------EQFI-NYARQIVSA-LTFVHSKNIAHRDIKPGNILIDSLGHIKLSDFGISI
 .       .  .|..||.  ||  | .. |.| .|             |. |  ..|||. . | . ||..| ||||||.|||.     .||.|||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

TNANNMI----------------E--PFSGSLLYMPPEIILKKPHNPM------QADIWSLGVLFAYMINGRAPW-QCDNVNSLRTCIIAG---------
  ...|                 .   | |.  .| ||.|..  ..        ..|||||| .   |..|. ||    .   .   .. .         
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----DFKLRANTP---------------------PEIIDLISKMMRIDPNERPSVAEILN--YKLF
    .   .  ..                     || .| |.|  ..|||.||.. . |.   . .
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase 91798.m00159.AA MELK 12-263 32 3.8e-46 155.55 In-house 1-254 (254) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-254/254
Sequence Identity: 32% (83 aa)

YGFKKLIGKGGFSFVYLVESEDDHKKYCAKVTPLNNDIILGVKIDPLEAEIKALMSLSHQNIIRLYDHFTENNCFFIILEYCQLGSMQD-TLNKKGLPKE
|   . || |||. | |       ..   |.   |.   ||  .  ...|. || .|.||.| .||     .. .|...|||  | | |  . .. |  |
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQ---LGHDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEE

QFINYARQIVSALTFVHSKNIAHRDIKPGNILIDSLGHIKLSDFGISITNANNMIEP----FSGSLLYMPPEIILKKPHNPMQADIWSLGVLFAYMINGR
.   . ||||||. .|||.  ||||.|| |.|.|   |.|| |||.      .. .       ||. |  ||.|  |      ||.||.|.|   .. | 
ETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGF

APWQCDNVNSLRTCIIAGDFKLRANTPPEIIDLISKMMRIDPNERPSVAEILNYKLF
 |.. ||.  .   |. | ..      || ..|. .|. .||. | |. ..||    
LPFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV

Kinase 91798.m00159.AA TyrKc 12-263 20 7.3e-14 1.48 SMART 1-280 (280) Show / Hide
Range on Protein: 12-263
Range on HMM: 1-280/280
Sequence Identity: 20% (64 aa)

YGFKKLIGKGGFSFVYLVESEDDHKKYCAKV---TPLNNDIILGVKIDPLEAEIKALMSL--SHQNIIRLYDHFTEN-------NCFFIILEYCQLGSMQ
  ..| .| | |  ||. .          .|   .  ..       .  .  |.. ...|  .|.||.|||   |.           .|..||. .|. .
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

DTLNKKG--LPKEQFINYARQIVSALTFVHSKNIAHRDIKPGNILIDSLGHIKLSDFGISITNANN--------MIEPFSGSLLY-------MPPEIILK
| | |..  |. ....... || .   . ||||. |||.   |.|... ...| |||| |    .         .. . ...          |.|| |  
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--

KPHNPMQA------DIWSLGVL----FAYMINGRAPWQC-----DNVNSLRTCIIAGDFKLRANT---------PPEIIDLISKMMRIDPNERPSVAEIL
     .        |.|| ||.    | |   |  |.        .   .. .. .|.   .            |.|. .....  . ||..||. .|| 
-----NYGKFTTKSDVWSFGVCMWEIFTY---GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-

NYKLF
 ...|
-HECF

Kinase 91798.m00159.AA Pkinase_Tyr 58-159 28 9.4e-13 43.81 Pfam 50-160 (270) Show / Hide
Range on Protein: 58-159
Range on HMM: 50-160/270
Sequence Identity: 28% (32 aa)

LEAEIKALMSL-SHQNIIRLYDHFT-ENNC--FFIILEYCQLGSMQDTLNKK-----GLPKEQFINYARQIVSALTFVHSKNIAHRDIKPGNILIDSLGH
. .|.| ...| .|.||.|||   | .      .|..||...|.. | | |.      |. .. .....|| ... . .|||. |||.   |.|... ..
FMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNV

IKLSDFGISIT
.| .||| . .
VKICDFGLARD