Gene 87835.m00232 (T.vaginalis)

87835.m00232

Species: T.vaginalis
Alias: TvagK0063, 87835.m00232
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
87835.m00232.AA Protein None 390 None Fasta, JSON
87835.m00232.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 87835.m00232.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 87835.m00232.AA CAMKL 9-261 35 1.1e-101 325.34 In-house 1-297 (297) Show / Hide 
Range on Protein: 9-261
Range on HMM: 1-297/297
Sequence Identity: 35% (108 aa)

YEVQHKIGDGGFAEVYYAIH-KASGLPVAIKKIP--KIV-DDNDSHLAL---------VRREIDIMKHIP---HPFIADFYEVLENNDF------IFIVM
|..   .| |.|..|  |.| .  |  |||| |   ||  |.. .   .         .|||| |||..    || |  .|||.|. ..      |..||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYISNGT--LRNTLNEM----GPFTEENAAIIFAQIVLVLKFLHQKCNVVHRDLKSDNILFDKNG--NIRVIDFGLSNT-----KATDEILKTQCGTPSY
||.|.|   | . . .     |...|. |  .| |||  ....|... .||||.| .|||.|.||  || .||||.||      . ... |||.||.|.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

ASPEMILG--EKYD-YSSDIWSAGIVLYEIVTGNLPFDDP--------NMARLAQKIIFKEVEFP--SGMSSQLIDLIQKLLTKDQTKRIKLSEIEEHPW
..||...|  ..|| .  ||||.|..|| .|.|.|||||.        |  .|  ||.    ..|  . .| ...|||.|.|... .||... .|..|||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

V
.
M
Kinase 87835.m00232.AA CAMK 14-261 23 6.4e-99 319.39 In-house 1-425 (425) Show / Hide 
Range on Protein: 14-261
Range on HMM: 1-425/425
Sequence Identity: 23% (102 aa)

KIGDGGFAEVYYAIHKASG------------LPVAIKKIPK--IVDDN-----------------------DSHLALVRREIDIMKH-------IPHPFI
..| |.|..|. .||| ..              |||| |.|  . |..                       .. .. |||||.|||.       . || |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ADFYEVLEN-------------------NDFIFIVM---EYISNG----TLRNTLNEMGP---------------FTEENAAIIFAQIVLVLKFLHQKCN
  .||| |.                   ......||   ||.|.|     | . . | |.               |||. |. .| ||.  ....|..  
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-

VVHRDLKSDNILFDKN-----------------GNIRVIDFGLSNTKAT------------------------DEILKTQCGTPSYAS-PEMILG-----
.|||||| .|||.|.|                 .|| .||||..| .                          .. .||.||||.|.. ||...|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------EKYDYSSDIWSAGIVLYEIVTGNLPFDDP-------------NMARLAQKIIFKEVEFPSG------------------------MSSQLI
         . |....|.||.|..||  ..| .||...             |. .| .||.  . .||.                          | . .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLIQKLLTKDQTKRIKLSEIEEHPWV
|||.|.|..| .||...... .|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 87835.m00232.AA MARK 9-261 39 2.3e-96 315.48 In-house 1-262 (262) Show / Hide 
Range on Protein: 9-261
Range on HMM: 1-262/262
Sequence Identity: 39% (105 aa)

YEVQHKIGDGGFAEVYYAIHKASGLPVAIKKIPKIVDDNDSHLALVRREIDIMKHIPHPFIADFYEVLE--NNDF-IFIVMEYISNGTLRNTLNEM--GP
|..   || |..|.|. |.|| .|  |||| ..|   .    .  |.|||.|||.. || |  ...| |  ..   |...|||.|.| |.. . .   |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FTEENAAIIFAQIVLVLKFLHQKCNVVHRDLKSDNILFDKNG--NIRVIDFGLSNTKATDEILKTQCGTPSYASPEMILGEKYD-YSSDIWSAGIVLYEI
 .|| |  || |||  ....|.|  .||||.| .||| |.||  ||  ||||.|.   ... |.| ||||.|..||..|...|| .  |||| |.||| .
LHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

VTGNLPFDDPN--MARLAQKIIFKEVEFPSGMSSQLIDLIQKLLTKDQTKRIKLSEIEEHPWV
|.|..|||. .  .  | .||   . ..|. .| .. .|||.||| .  .|....||..|||.
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
S_TKc 87835.m00232.AA S_TKc 9-261 34 3.7e-96 326.68 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-261
Range on HMM: 1-231/231
Sequence Identity: 34% (92 aa)

YEVQHKIGDGGFAEVYYAIHKASGLPVAIKKIPKIVDDNDSHLALVRREIDIMKHIPHPFIADFYEVLENNDFIFIVMEYISN--GTLRNTLNEMGP---
||.  ||| |.|..|| ..|| .|  ||||.|.            .||||.|.|.  ||.|  .|.| .. |....||||...  |.|.  . ..|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FTEENAAIIFAQIVLVLKFLHQKCNVVHRDLKSDNILFDKNGNIRVIDFGLSNTKATDEILKTQCGTPSYASPEMILGEKYDY-SSDIWSAGIVLYE
   |.|  |. ...||.. |...|.. ...||||| .|||.|.  .| ..||||.         .|.|||| | .||..   .|.. ..|.|| |..|||
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

IVTGNLPFDDPNMARLAQKIIFKEVEFPSGMSSQLIDLIQKLLTKDQTKRIKLSEIEE-------HPWV
 ..|  ||.  .|... .||           |....|.|.|.|.|| .||.   |. .       |||.
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 87835.m00232.AA AMPK 9-261 41 1.9e-87 259.71 In-house 1-254 (254) Show / Hide 
Range on Protein: 9-261
Range on HMM: 1-254/254
Sequence Identity: 41% (106 aa)

YEVQHKIGDGGFAEVYYAIHKASGLPVAIKKIPKIVDDNDSHLALVRREIDIMKHIPHPFIADFYEVL-ENNDFIFIVMEYISNGTLRNTLNEMGPFTEE
| .. .|| | |  |  ..|.  |  |||| . |    ...    ..|||.|.| . || |   |||. | .. ||.||||.|.| |       |  .|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

NAAIIFAQIVLVLKFLHQKCNVVHRDLKSDNILFDKNGNIRVIDFGLSNTKATDEILKTQCGTPSYASPEMILGEKYD-YSSDIWSAGIVLYEIVTGNLP
 |.  |.||.  .  .| . ..||||||  |.|.|.| || . ||||||.    | ||| || | ||.|||| | .|     |||| |..||  . | ||
EACRFFQQIISGVEYCH-RHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

FDDPNMARLAQKIIFKEVEFPSGMSSQLIDLIQKLLTKDQTKRIKLSEIEEHPWV
|||.| . | .||.  |.. |. .|..  |||...|..| .|||. ..| .||| 
FDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 87835.m00232.AA QIK 9-261 37 1.5e-84 287.23 In-house 1-272 (272) Show / Hide 
Range on Protein: 9-261
Range on HMM: 1-272/272
Sequence Identity: 37% (103 aa)

YEVQHKIGDGGFAEVYYAIHKASGLPVAIKKIPKIVDDNDSHLALVRREIDIMKHIPHPFIADFYEVLENNDFIFIVMEYISNGTLRNTLNEMGP-----
|..   || | || |  | |.     |||| | |   |  . |  . ||. ||| . ||.|   |.|.|  | ..||.|| ||| .  .|.. |      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDE-ENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------FTEENAAIIFAQIVLVLKFLHQKCNVVHRDLKSDNILFDKNGNIRVIDFGLSNTKATDEILKTQCGTPSYASPEMILGEKYD-YS
                .|. |. .| ||..  ...|.. |.||||||  |||.|.| || ..|||.||   ... |.| ||.| || ||| .|..||   
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKR-NIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK

SDIWSAGIVLYEIVTGNLPFDDPNMARLAQKIIFKEVEFPSGMSSQLIDLIQKLLTKDQTKRIKLSEIEEHPWV
.|||| |.|||  |.| |||| ...  | |...   .  |  ||. . .|| . |. | ..|.    | .|.| 
VDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 87835.m00232.AA Ciliate-E2-Unclassified 9-261 28 6.8e-83 281.7 In-house 1-352 (352) Show / Hide 
Range on Protein: 9-261
Range on HMM: 1-352/352
Sequence Identity: 28% (101 aa)

YEVQHKIGDGGFAEVYYAIHKASGLPVAIKKIPKIVDDN-----DSHLALVRREIDIMKH------------------IPHPFIADFYEVLENNDFIFIV
|.....|| |||..|| ..||  ..  |.| . || ...      ..  ... .. ....                  .|||||  .... .. . |.||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYISNGTLRNTLNEMGP-----------------FTEENAA-----IIFAQIVLVLKFLHQKCNVVHRDLKSDNILFDKNG---NIRVIDFGLSNTKAT
|||. .|.|.. .....                  |||..|.      .||||.. |..||.| |..|||.| .|||||.||   .|..||||.|    .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

D----------------EILKTQCGTPSYA----SPEMILGEKYD----YSSDIWSAGIVLYEIVTGNLPFDDPNMAR----------------LAQKII
.                ....|.||||.|     .||.. |..||    |..|||| |..|||...|..||.|.|                   | |.|.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

FKEVEFPS--------GMSSQLIDLIQ----KLLTKDQTKRIKLSEIEEHPWV
 |...||.        . | . .|.|.    |.| |.. ||| ...| .||| 
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 87835.m00232.AA Pkinase 9-261 31 1.2e-81 282.41 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-261
Range on HMM: 1-293/293
Sequence Identity: 31% (93 aa)

YEVQHKIGDGGFAEVYYAIHKASGLPVAIKKIPKIVDDNDSHLALVR-REIDIMKHIPHPFIADFYEVLENNDFIFIVMEYISNG----TLRNTLN--EM
|..  ||| |.|..|| ..|| .|  ||.|.|.|  .. . . ...| .|| |||.. ||.|  .|.. |..| | .||||  .|     |   .   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPF--TEENAAIIFAQIVLVLKFLHQKCNVVHRDLKSDNILFDKNGNI----RVIDFGLSNT--KATDEILKTQCGTPSYASPEMIL-GEKYDYSSDIWS
|.|  .|. .  .. ||.  |...|. ....|||||..|||.|.||.|    ...||||.       .. ..| |||| |..|| |. |..|....|.||
GCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

AGIVLYEIVTGNLPFDDP------NMARLAQKIIFKEVEFPSG---------------------MSSQLIDLIQKLLTKDQTKRIKLSEIEEHPWV
.|..||| ..|..||..       ..  . ..|  ....|..                      .|. ..|.| ..|.|| .||.   .| .|||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 87835.m00232.AA Ciliate-E2 9-261 26 5.7e-78 265.35 In-house 1-365 (365) Show / Hide 
Range on Protein: 9-261
Range on HMM: 1-365/365
Sequence Identity: 26% (100 aa)

YEVQHKIGDGGFAEVYYAIHKASGLPVAIK-----------------KIPKIVDDNDSHLALVRREIDIMKHIP----------------HPFIADFYEV
|... ||| |.|. ||.. ..  .  .|||                 ||  .   . . .  . .||.||. |                 ||.|  .||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LE--NNDFIFIVMEYISNGTLRNTLNEM-----------GPFTEENAAIIFAQIVL---------------VLKFLHQKCNVVHRDLKSDNILFDKNGNI
 .  ... |..||||.. |.|.  ....           ..|||. .. |..||.                 |..||.| |..|||.| .||||     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RVIDFGLSNTKATD--------------------------------EILKTQCGTPSYASPEMILGEK---------YDYSSDIWSAGIVLYEIVTGNLP
 .||||||    .|                                .. .|.|||| | .||.. |.|         |||..||||.|..||| ..|..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FDDPNMARLAQKIIFKEVEFP------------------SGMSSQLIDLIQK----LLTKDQTKRIK-LSEIEEHPWV
|         |.|. ....||                     | . .|||.|    .| ||. |||   ..| .||| 
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 87835.m00232.AA ULK 9-261 26 1.2e-74 254.3 In-house 1-324 (324) Show / Hide 
Range on Protein: 9-261
Range on HMM: 1-324/324
Sequence Identity: 26% (86 aa)

YEVQHKIGDGGFA-EVYYAIHKAS---GLPVAIKKIPKIVDDNDSHLA-------LVRREIDIMKHIP---HPF--IADFYEVLENNDF--IFIVMEYIS
|.. |..| | |.  || ...| .   .  ||.|.|.|    ......       | ..|| ||| .    ||.  |  .|...|. ..  |.|.|||  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGTLRNTLNEMGP---------FTEENAAIIFAQIVLVLKFLHQKCNVVHRDLKSDNILFDKNGN------------IRVIDFGLSNT----KATDEILK
 |.|.. ... ..         ..|. | ..| ||.  .|.||.. |..|||.| .|||  ..              . . |||.. .       . ...
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKH-NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

TQC------GTPSYASPEMIL----GEKYD-YSSDIWSAGIVLYEIVTGNLP----FDDPN--MARLAQK-------IIFKEVEFP-----SGMSSQLID
|..      ||| | .|. .     ...|. | .|||| |...||...|  |    | | .  ...| ..       |  . ..||        |....|
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LIQKLLTKDQTKRIKLSEIEEHPWV
||...|..|...||   || .|||.
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 87835.m00232.AA AktR 9-261 37 2.1e-72 246.88 In-house 1-268 (268) Show / Hide 
Range on Protein: 9-261
Range on HMM: 1-268/268
Sequence Identity: 37% (101 aa)

YEVQHKIGDGGFAEVYYAIHK-ASGLPVAIKKIPKIVDDNDSHLALVRREIDIMK-HIPHPFIADFYEVLENNDFIFIVMEYISNGTLRNTLNEMGPFTE
..|   .| |.|..|| . .|  ..  .|.| | |    .      ...| .||. .. ||||  ...  .... .|..|||. .| | . |.  . |.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

ENAAIIFAQIVLVLKFLHQKCNVVHRDLKSDNILFDKNGNIRVIDFGLSN---TKATDEILKTQCGTPSYASPEMILG-EKYDYSSDIWSAGIVLYEIVT
| | ..||||.| | .|||. |.. |||| .||| |..|... .|||||.    .. ||. .. |||| | .||||.  . ...|.|.|. ||..||.||
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GNLPFDDPNMARLAQKIIFKE---VEFPSGMSSQLIDLIQ-KLLTKDQTKRIK-----LSEIEEHPWV
|. ||.. |  .. |||..|.   ...||  |||. |||| ||| |...||..      .|| .||| 
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 87835.m00232.AA ULK 9-261 26 1.3e-71 244.17 In-house 1-329 (329) Show / Hide 
Range on Protein: 9-261
Range on HMM: 1-329/329
Sequence Identity: 26% (88 aa)

YEVQHKIGDGGFAEVYYAIHKAS----GLPVAIKKIPKIVDDNDSHLA-------LVRREIDIMKHIP--------HPFIADFYEVLENNDF--IFIVME
|.. |..| | |. || ...| .    .  ||.|.|.|   .......       |...||.||| .         || |  .|...|. ..  |.|.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YISNGTLRNTLNEMGP----------FTEENAAIIFAQIVLVLKFLHQKCNVVHRDLKSDNILFDKN------------GNIRVIDFGLSNTKATD----
|   |.|.. ... ..          ..|. | ..| ||.  .|.||.. |..|||.| .||| ...            | . . |||.. .   |    
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKH-NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

EILKTQC------GTPSYASPEMIL----GEKYD-YSSDIWSAGIVLYEIVTGNLP----FDDPN---MARLAQK-------IIFKEVEFP-SG----MS
....|.       ||| | .|. .     ...|. | .|||| |...||...|  |    | | .   . .| ..       |  .  .|| .|     |
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

SQLIDLIQKLLTKDQTKRIKLSEIEEHPWV
....|||...|..|...||   |. .|||.
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 87835.m00232.AA Pkinase_Tyr 9-219 28 1.2e-19 67.13 Pfam 1-228 (270) Show / Hide 
Range on Protein: 9-219
Range on HMM: 1-228/270
Sequence Identity: 28% (65 aa)

YEVQHKIGDGGFAEVYYAIHK----ASGLPVAIKKIPKIVDDND-SHLALVRREIDIMKHI-PHPFIADFYEVLE-NNDF--IFIVMEYISNGTLRNTLN
 .  .|.| | | ||| .. |      ..|||.|...   .. .  . .. | |. |||..  || |  .| |     .   |.|||||  .| |.. | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

EM----GPFTEENAAIIFAQIVLVLKFLHQKCNVVHRDLKSDNILFDKNGNIRVIDFGLSNTKATDEIL-KTQCGTPS---YASPEMILGEKYDYSSDIW
.     .|.| .    . .||   . .|..|   .||||   |.| ..|. ... ||||. .   |.   ... |..      .|| |   |.   ||.|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN-CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SAGIVLYEIVT-GNLP-FDDPNMARLAQKI
| |....||.| |  | . .   ... ..|
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYI
Kinase 87835.m00232.AA TyrKc 9-259 24 1.2e-16 46.18 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-259
Range on HMM: 1-280/280
Sequence Identity: 24% (70 aa)

YEVQHKIGDGGFAEVYYAIHKASGLPVAIKKIPKIVDDNDSHLALVRREIDIMKHI--PHPFIADFYEVLENN-------DFIFIVMEYISNGTLRNTLN
 .  .|.| | | ||| .. |   ..||.|.. .        ..  .||. ||...   || |  .| |           . ..||||| ..| |.. | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

EMGP-FTEENAAIIFAQIVLVLKFLHQKCNVVHRDLKSDNILFDKNGNIRVIDFGLSNTKATD-------EILKTQC--GTPS-----YASPEMILGEKY
. .| .. .    .  ||     .||.| |..||||   |.| ..|. ... |||||     |       .  ...   |. .       .|| |   |.
KHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

DYSSDIWSAGIVLYEIVT-GNLPFDD-----PNMARLAQKIIFK-EVEFPSG--------MSSQLIDLIQKLLTKDQTKRIKLSEIEEHP
   ||.|| |....|| | |  |  .      . ... ...      . |          ... . .....    |  .|   ||| |  
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF