Gene 94734.m00162 (T.vaginalis)

94734.m00162

Species: T.vaginalis
Alias: 94734.m00162, TvagK0609
External Links:
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK7

Sequence

Name Sequence Type Origin Length Description Download
94734.m00162.AA Protein None 367 None Fasta, JSON
94734.m00162.kin_dom Protein Kinase Domain None 288 None Fasta, JSON

Protein domain

Protein domains of 94734.m00162.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94734.m00162.AA ERK7 20-307 52 8.9e-159 533.77 In-house 1-292 (292) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-292/292
Sequence Identity: 52% (154 aa)

YEVIKKIGQGAYGVVWRVLNKQTQQVVALKKVFGAFQNVTDALRTYREITFLRQLQNHPDIVSLLAVHRAENDLDIYLVFECLETDVNAVIR-AKILLDV
||..|..|.||||.||... |.|.|||||||.| ||.| ||| ||.|||.||.....|| |..|. | ||.||.||||||| .||| .|||| ..|| |.
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIRKGNILKDI

HHRYIFWQLLCALKYIHSAGIIHRDLKPSNLLINSDASIKLCDFGLARSIDTDD----NPTELTDYIATRWYRAPEILFGSSSYSFGVDMWAAGCILAEL
| .||..||| |.||.||. .|||||||||.|..|.  .|.|||||||||   .    .   ||.|.||||||||||| ||  |  |||||  ||||.|.
HKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGEM

VSGRPLFPGSSAMDQLERIISYTGPLSPAEIESMDSSFTQTMLSNLSYSRPRFSLEEKLEGAPPDAIDLIKKLISFDPKERPTAEECLEHPYV
. |.|.|||.| |.|.|.|.  ..  . ..||...|..  .||...  ...| .|.. ......|||||.|.|. | ||.| |||..|.||||
LRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMN-QQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase 94734.m00162.AA MAPK 20-307 41 3.8e-141 475.22 In-house 1-328 (328) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-328/328
Sequence Identity: 41% (135 aa)

YEVIKKIGQGAYGVVWRVLNKQ------TQQVVALKKVFGAFQNVTDALRTYREITFLRQLQNHPDIVSLLAVHRAE-----ND----LDIYLVFECLET
|. .|.|||||||||. .  |       ... ||.||.. .|||.|.. |||||| .|| . .|. |..|| . ..|     |.     |||.|.|  ||
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DVNAVIR-AKILLDVHHRYIFWQLLCA--LKYIHSAGIIHRDLKPSNLLINSDASIKLCDFGLARSIDTD-------DNP-----TELTDYIATRWYRAP
| ...|.  ..| | | .|...|.|..  |||||||..|||||||||.|.|..   |.||||||||||..       |.|     . .|.|.||||||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EILFG--SSSYSFGVDMWAAGCILAELVS-GRPLFPGSSAMDQLERIISYTGPLSPAEIESMD-SSFTQTMLSNL--SYSRPRFSLEEKLEG----APPD
||...  .  |. .||||..|||.||... ..|||||.. .||...|....|  |.  |. .  |.   .....|     .|. ..|. . .    | |.
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQ

AIDLIKKLISFDPKERPTAEECLEHPYV
||||..|.  |||..| |.||.|.|||.
AIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 94734.m00162.AA CMGC 20-307 23 4e-128 423.48 In-house 1-513 (513) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-513/513
Sequence Identity: 23% (122 aa)

YEVIKKIGQGAYGVVWRVLN--------------KQTQQVVALKKVFGAFQNVTDAL----------RTYREITFLRQLQ---------------NHPD-
||.|||||.|.||||..  .              ..|...||.||.. .| . ..|.          |..||| .|..|.               .|.  
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVSLLAVHRAEN---------------DLDIYLVFECLETDVNAVIR-----------------------------AKILLDVHHRYIFWQLLCALK--Y
||.|. . . .|               . ..|||||....|   .|.                              | ..  | | ...|.|..||  |
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

IHSAG--IIHRDLKPSNLLINSD--------------------ASIKLCDFGLARSIDTDDNPTE-------------------LTDYIATRWYRAPEIL
.||..  ||||||||.|.|||..                      .|.|||||||.... .....                   .|.|..||||||||||
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

FGSSSYS---------FGVDMWAAGCILAELVSG--------RPLFPGSSA-----------MDQLERIISYTGPLS---------------PAEIESMD
.|.. |.          ..|||..|||.||.. |        .|||||.|             |||..|.   |. .               . |. .| 
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

S----------------------SFTQTMLSNLSYSRPRF-SLEEKLEG-----------------------------------APPDAIDLIKKLISFD
.                      .  .   ||... .... .....  .                                   ..|.||||.||.  .|
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

PKERPTAEECLEHPYV
|..|.|||..|.||| 
PDKRITAEQALQHPYF
Kinase 94734.m00162.AA ERK 20-307 42 3.7e-115 388.86 In-house 1-307 (307) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-307/307
Sequence Identity: 42% (132 aa)

YEVIKKIGQGAYGVVWRVLNKQ-----TQQVVALKKVFGAFQNVTDALRTYREITFLRQLQNHPDIVSLLAVHRAE---NDLDIYLVFECLETDVNAVIR
|. ||.||.||||||  . .|      |.| || ||.. || .  .. ||.||| .|| .  |. |..|. . . .   .  |||.|.|  |||   .|.
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPEQYNDIYCVEELMETDLHQIIN

AK-ILLDVHHRYIFWQLLCALKYIHSAGIIHRDLKPSNLLINSDASIKLCDFGLARSIDT--DDNPTE----LTDYIATRWYRAPEILFGSSSYSFGVDM
 .  | | |  |  .|.||.|||||||..|||||||||.|.||.   | ||||||| .|.  ..|...    .|.|.||||||||||.   . |.  .|.
SQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMDI

WAAGCILAELVSGRPLFPGSSAMDQLERIISYTG-PLSPAEIESMDSSFTQTMLSNLSY-SRPRFSLEEKLEGAP--PDAIDLIKKLISFDPKERPTAEE
|..|||.||.. ..||||| . ..|..||....| | |  ...  .|  .. ...||..  ||  ..|.    |.  |.||||..|.. |||..| |.||
WSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITVEE

CLEHPYV
|||||| 
CLEHPYF
Kinase 94734.m00162.AA S_TKc 20-307 31 1.1e-99 338.36 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-231/231
Sequence Identity: 31% (95 aa)

YEVIKKIGQGAYGVVWRVLNKQTQQVVALKKVFGAFQNVTDALRTYREITFLRQLQNHPDIVSLLAVHRAENDLDIYLVFECLET---DVNAVIRAKI--
||...|||.||.|.|... .| |...||.|..           ...|||  |..  .|| || |. | .     ..|.|.|....   |.  .|. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LLDVHHRYIFWQLLCALKYIHSAGIIHRDLKPSNLLINSDASIKLCDFGLARSIDTDDNPTELTDYIATRWYRAPEILFGSSSYSF-GVDMWAAG
     .   | |....|..|||.|.|| |||||||||.|.|...   ||.||||||| .         | .. |.||.|||.|    .|..  .|.|. |
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL----GYGKCKCDWWSCG

CILAELVSGRPLFPGSSAMDQLERIISYTGPLSPAEIESMDSSFTQTMLSNLSYSRPRFSLEEKLEGAPPDAIDLIKKLISFDPKERPTAEECLE-----
|||.|...|.|.||    |... ..|                                          .|.|.|.|.|.  .||..|||| |.|.     
CILYEMLCGYPPFP---QMQMMFKKIG-----------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDI

--HPYV
  ||..
KCHPWF
Kinase 94734.m00162.AA p38 20-307 40 1e-93 317.66 In-house 1-289 (289) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-289/289
Sequence Identity: 40% (121 aa)

YEVIKKIGQGAYGVVWRVLNKQTQQV---VALKKVFGAFQNVTDALRTYREITFLRQLQNHPDIVSLLAVHRA----ENDL-DIYLVFECLETDVNAVIR
|. .. .|.|||| |  .  ..|.|    || || .  || . .| |||||.  |. .. |  ...|| |       .||. |.|.| .  ..| | ...
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMR-HENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMK

AKILLDVHHRYIFWQLLCALKYIHSAGIIHRDLKPSNLLINSDASIKLCDFGLARSIDTDDNPTELTDYIATRWYRAPEILFGSSSYSFGVDMWAAGCIL
 . | | | ...  |.| .||||||||||||||||||. .| |  ..  ||||||. |     .|.|.|.||||||||||..    |   ||.|  |||.
CQRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLARHCD-----DEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIM

AELVSGRPLFPGSSAMDQLERIISYTGPLSPAEIESMDSSFTQTMLSNLSYSRPRFSLEEKLEGAPPDAIDLIKKLISFDPKERPTAEECLEHPYV
|||..||.||||.  .|||.||.. .|  ..  .. . |    . . ...  .||  ... . || | ||||. |.   ||  | |||| ..||| 
AELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYP-QMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHPYF
Kinase 94734.m00162.AA Pkinase 20-307 33 3.3e-92 317.43 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-293/293
Sequence Identity: 33% (103 aa)

YEVIKKIGQGAYGVVWRVLNKQTQQVVALKKVFGAFQNVTD---ALRTYREITFLRQLQNHPDIVSLLAVHRAENDLDIYLVFECLET-----DVNAVIR
|....|||.|..|.|..  .| |...||.|..    ..      ..|. .||  .. | ||| || |. . .   . .||.|.|..|      |  ..|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIS

---AKIL--LDVHHRYIFWQLLCALKYIHSAGIIHRDLKPSNLLINSDASI----KLCDFGLARSIDTDDNPTELTDYIATRWYRAPEILFGSSSYSFGV
    . .   . . . ...|.|..|.|.|| |||||||||.|.||...  |    |.||||||. .|   | . .|..  |.||.|||.. |.. |.  |
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DMWAAGCILAELVSGRPLFPGS----SAMDQLERIISYTGPLSPAEIESMDS--SFTQTMLSNLSYSRPRFSLEEKLEGAPPDAIDLIKKLISFDPKERP
|||..||||.|...|||.|||.    . .||...|    ||  . ...  .|   |. ..    .     | ....   ......|.||... .|||.||
DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-----F-HWTF-HNWSEECKDFIKWCLCKDPKKRP

TAEECLEHPYV
|||..|.||..
TAEQILQHPWF
Kinase 94734.m00162.AA CDK 20-238 37 3.6e-89 285.44 In-house 1-242 (284) Show / Hide 
Range on Protein: 20-238
Range on HMM: 1-242/284
Sequence Identity: 37% (95 aa)

YEVIKKIGQGAYGVVWRVLNKQTQ-----QVVALKKVFGAF---QNVTDALR--TYREITFLRQLQNHPDIVSLLAVHRAEN---------DLDIYLVFE
|| ..|||.|.|||| .  .|||.     |.|||||.       ..  . .   . |||. |..|  || ||.|. |   .|         .  .|.|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

CLETDVNAVIRAKILLDVHHRYIFWQLLCALKYIHSAGIIHRDLKPSNLLINSDAS-----IKLCDFGLARSIDT----DDNPT-ELTDYIATRWYRAPE
 ...|   ...         . ..|||| .| |.|| .|.||||||.|.|||.. .     .|. ||||||        .  |. ..|  . |.||||||
YMDHDLKKYMD--------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMS-EPNRTYTHEVVTLWYRAPE

ILFGSSSYS--FGVDMWAAGCILAELVS---GRPLFPGSSAMDQLERIISYTG
.|.||. ||   ..|||..|||.||..    ..|||||.|  |||..|.   |
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICG
Kinase 94734.m00162.AA CDKL 20-307 37 2.1e-82 280.09 In-house 1-286 (286) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-286/286
Sequence Identity: 37% (112 aa)

YEVIKKIGQGAYGVVWRVLNKQTQQVVALKKVFGAFQNVTDALRTYREITFLRQLQNHPDIVSLLAVHRAENDLDIYLVFECLETDVNAVIRAKI--LLD
|| . |.| |.||||    || |.|.|| ||      .     .. ||| .|.||  |. ||.|. | |  . |  .||||  .  |  .   .   . .
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLK-HENIVNLIEVFRRKRKL--HLVFEYCDHTVLHELEEYPNGVDE

VHHRYIFWQLLCALKYIHSAGIIHRDLKPSNLLIN-SDASIKLCDFGLARSID-TDDNPTELTDYIATRWYRAPEILFGSSSYSFGVDMWAAGCILAELV
   | . ||.| |... |.  .|||| || |.||. ..  .||||||.|| .  ....   .||| ||||||||| | |  .|.  ||.||.||..||..
HVVRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFARMLAKPGEI---YTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMI

SGRPLFPGSSAMDQLERIISYTGPLSPAEIESMDSS--FTQTMLSNLSYSRPRFSLEEKLEGAP-PDAIDLIKKLISFDPKERPTAEECLEHPYV
.| ||.||.|  ||| .|.   ||| |  .|   ..  |    .   .    . .||... ..  . |.|..||.   || ||.|.|....||| 
DGQPLWPGQSDIDQLYHIQKCLGPLIPRHQEIFSKNPFFHGMKFPEIE---HMEPLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase 94734.m00162.AA ERK5 20-307 37 3.3e-80 272.78 In-house 1-295 (295) Show / Hide 
Range on Protein: 20-307
Range on HMM: 1-295/295
Sequence Identity: 37% (111 aa)

YEVIKKIGQGAYGVVWRVLNKQTQQVVALKKVFGAFQNVTDALRTYREITFLRQLQNHPDIVSLLAVHRAENDL----DIYLVFECLETDVNAVIRAKIL
|..| |||.||||||    .... | ||.||.  ||  || | ||.||.  ||  . |  |. .  . . .  .    |.| ||. .| |.  .| .   
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFR-HDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQP

LDVHH-RYIFWQLLCALKYIHSAGIIHRDLKPSNLLINSDASIKLCDFGLARSIDT---DDNPTELTDYIATRWYRAPEILFGSSSYSFGVDMWAAGCIL
. . | ||  .|.|  |||.||| .|||||||||||.|    .|. |||.|| . |   |.    .|.|.|||||||||..| |  |   .|.|. |||.
FTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGCIF

AELVSGRPLFPGSSAMDQLERIISYTGPLSPAEIESMDSSFTQTMLSN-LSYSRPRFSLEEKLEGAPPDAIDLIKKLISFDPKERPTAEECLEHPYV
 |... | .|||   ..||. |.   |  .|. |... .   .  .   ..  .|.  .|.   .| . |.||. ... |.| || |. . | ||..
GEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPK-DWEKVYPKADRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase 94734.m00162.AA RCK 20-235 37 4.5e-70 221.45 In-house 1-228 (298) Show / Hide 
Range on Protein: 20-235
Range on HMM: 1-228/298
Sequence Identity: 37% (87 aa)

YEVIKKIGQGAYGVVWRVLNKQTQQVVALKKVFGAFQNVTDALRTYREITFLRQLQNHPDIVSLLAVHRAENDLDIYLVFECLETDVNAVIRA----KIL
| .||..| |.||.|    || |...|| ||    | .  .. .  |||..|| |  || |. |. | | ...   |.|||......   ..     . .
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMN-LREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKY

LDVHH---RYIFWQLLCALKYIHSAGIIHRDLKPSNLLINS---------DASIKLCDFGLARSIDTDDNPTELTDYIATRWYRAPEILFGSSSYSFGVD
|       . |. |.| .|...|. |. |||||| |.....         .  ||..||||.|.|  . .|   |||. ||||||||.|  .  |.  .|
LPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREI-RSKPP--YTDYVSTRWYRAPECLLRCTYYNSPMD

MWAAGCILAELVSGRPLFPGSSAMDQLERIIS
.|| ||| .|| . |||||||| .||.  |..
IWAVGCIMYELYMLRPLFPGSSEIDQIFKICK
Kinase 94734.m00162.AA MAPK-Unclassified 20-173 44 8.2e-57 195.06 In-house 1-164 (575) Show / Hide 
Range on Protein: 20-173
Range on HMM: 1-164/575
Sequence Identity: 44% (74 aa)

YEVIKKIGQGAYGVVWRVLNKQT-QQVVALKKVFGAFQNVTDALRTYREITFLRQLQNHPDIVSLLAVHRAENDLD-----IYLVFECLET---DVNAVI
||..| ||.||||.| |   |..  | || ||| ..|.|.||. |. |||  || | ||| |. .  . ... ..      ||.| .  .|   |   .|
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYL-NHPNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQII

RAKI--LLDVHHRYIFWQLLCALKYIHSAGIIHRDLKPSNLLINSDASIKLCDFGLARSIDTDDN
.  .  . . | .|.| |.|  |||.|||.|||||||||||||| | |.. ||||..|||  . |
KSNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSRSIEDNQN
Kinase 94734.m00162.AA MAPK-Unclassified 176-238 32 1.8e-25 88.73 In-house 404-497 (575) Show / Hide 
Range on Protein: 176-238
Range on HMM: 404-497/575
Sequence Identity: 32% (31 aa)

ELTDYIATRWYRAPEILFGSSSYSFGVDMWAAGCILAELVSG-----------RPLFPGSS--------------------AMDQLERIISYTG
..| |..|||||||||.. .. |.. ||.|..|||.||...            ||||||..                      ||.  |..| |
HMTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLG
Kinase 94734.m00162.AA TyrKc 20-310 23 3.4e-15 22.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-310
Range on HMM: 1-280/280
Sequence Identity: 23% (74 aa)

YEVIKKIGQGAYGVVWRVLNKQTQQVVALKKVF-GAFQNVTDALRTYREITFLRQL-QNHPDIVSLLAVHRAE-----NDLDIYLVFE-CLETDVNAVIR
 . .||.| ||.|.|..   |   . || |..  .|          .||.  ...|  .|| || |..| . .      .  ...|.| .   | .  .|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

AKI--LLDVHHRYIFWQLLCALKYIHSAGIIHRDLKPSNLLINSDASIKLCDFGLARSIDTD-------DNPTE----LTDY-IATRWYRAPEILFGSSS
..   |   .  .. ||  |   |.|| ..|||||   | |....  .| .||||.| |. |       |  .      ... .  ||. ||| .   . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NYGK

YSFGVDMWAAGCILAELVS-GRPLFPG-----SSAMDQLERIISYTGPLSPAEIE--SMDSSFTQTMLSNLSYSRPRFSLEEKLEGAPPDAIDLIKKLIS
...  | |. |  . |. . | .  ||      |. . .|.. .   .  |....  |                   |       ..|..  ...|.   
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------F------VCCPDEMYQIMKQCWH

FDPKERPTAEECLEHPYVAQF
.||..||| .|.     . .|
EDPEDRPTFSEI-----HECF
Kinase 94734.m00162.AA RCK 276-307 40 4.3e-15 44.04 In-house 267-298 (298) Show / Hide 
Range on Protein: 276-307
Range on HMM: 267-298/298
Sequence Identity: 40% (13 aa)

APPDAIDLIKKLISFDPKERPTAEECLEHPYV
...|.|.|..|.   ||..|.||...|.||| 
CSQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase 94734.m00162.AA CDK 265-307 32 1e-10 30.38 In-house 256-284 (284) Show / Hide 
Range on Protein: 265-307
Range on HMM: 256-284/284
Sequence Identity: 32% (14 aa)

PRFSLEEKLEGAPPDAIDLIKKLISFDPKERPTAEECLEHPYV
| .              ||. |.  .||| | .||..|.||| 
PDY--------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 94734.m00162.AA MAPK-Unclassified 276-307 36 2.1e-09 29.66 In-house 535-575 (575) Show / Hide 
Range on Protein: 276-307
Range on HMM: 535-575/575
Sequence Identity: 36% (15 aa)

AP---------PDAIDLIKKLISFDPKERPTAEECLEHPYV
||         ...||...|.  |.|. | ||.. |||||.
APGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase 94734.m00162.AA Pkinase_Tyr 129-206 31 6.8e-08 27.35 Pfam 122-199 (270) Show / Hide 
Range on Protein: 129-206
Range on HMM: 122-199/270
Sequence Identity: 31% (25 aa)

CALKYIHSAGIIHRDLKPSNLLINSDASIKLCDFGLARSI-DTDDN-PTELTDYIATRWYRAPEILFGSSSYSFGVDMWA
... | .| ..|||||   | |....  .| ||||||| | ..|    .     .  .|. ||| .. .  ..   | |.
KGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM-APECINYGK-FTTKSDVWS
Kinase 94734.m00162.AA Pkinase_Tyr 20-36 41 0.009914 9.87 Pfam 1-17 (270) Show / Hide 
Range on Protein: 20-36
Range on HMM: 1-17/270
Sequence Identity: 41% (7 aa)

YEVIKKIGQGAYGVVWR
 . .||.|.||.|.|..
ITFGKKLGEGAFGEVYK