Gene 81840.m00166 (T.vaginalis)

81840.m00166

Species: T.vaginalis
Alias: 81840.m00166, TvagK0012
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
81840.m00166.AA Protein None 305 None Fasta, JSON
81840.m00166.kin_dom Protein Kinase Domain None 260 None Fasta, JSON

Protein domain

Protein domains of 81840.m00166.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81840.m00166.AA CAMKL 7-266 31 2.7e-102 327.25 In-house 1-297 (297) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-297/297
Sequence Identity: 31% (94 aa)

YEPHKFLGSGSFSGVWECQH-MTTGESVACKVIDINTAI-SDQVYYHFRN-----------ELLIHSKIH---HSSITQLKDIIIDKDN------IYIFI
|.  | || |||. |  ..| .|||| || |.||.. .   ...  ....           |  |.....   |  | .| ..| ....      ||.. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCDGGD--LNDIVQDVGG----LTEQEAKHYFHQIIDALSYIHKLGVAHRDVKLENILITADDD--AKLTDFGLCKQQR-G----NDPMLTTCGTLVYA
|.|.||.  | | ..  |.    ..| ||..|| ||..|..|.|..|..||| |.||||.. ...  .|..|||.. ..| .    .. . | ||.. |.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIIRE--EPYNGMKADIWSAGIVLYAMIAAHFPWVVPDD---LPPDILMKETAKQIASGDIILPDGISYELQNLLGNMLNVDPEERPTADEILQHPWF
||||.    .||.| |.||||.|..||||.  ..|.  ...      .|  ..  . .  . .  .  .| ....|.  ||.|.||.|||...|..|||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 81840.m00166.AA CAMK 12-266 23 7.8e-99 319.11 In-house 1-425 (425) Show / Hide 
Range on Protein: 12-266
Range on HMM: 1-425/425
Sequence Identity: 23% (99 aa)

FLGSGSFSGVWECQHM-TTG-----------ESVACKVIDINTAIS-------------------------DQVYYHFRNELLIHSK-------IHHSSI
 ||.|||. | .|.|  |||           . ||.|.|| . . .                         ..    .|.|. |..|       ..|  |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

TQLKDIIID-------------------KDNIYIFI---ELCDGG----DLNDIVQDVGG---------------LTEQEAKHYFHQIIDALSYIHKLGV
 .| ... |                   ....|..    |.|.||    || | ... |.               .||.||..||.||..|. |.|....
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDVKLENILITADD-----------------DAKLTDFGLCKQQRG------------------------NDPMLTTCGTLVYAA-PEIIRE------
.||| |.||||.. ..                 . |..|||. .. ..                        ...| | |||. |.| ||...       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------EPYNGMKADIWSAGIVLYAMIAAHFPWVVP---DDLPPD----ILMKETAKQIASGDIILP----------------DGISYE--------LQ
       .|| | |.|.||.|..||.|   ..|.  .   ...  |      ..|. ..| .|.   |                |.|| |         .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-DEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NLLGNMLNVDPEERPTADEILQHPWF
.|. .||.||||.|.|....|.|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 81840.m00166.AA S_TKc 7-266 35 1.1e-93 318.49 SMART 1-231 (231) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-231/231
Sequence Identity: 35% (98 aa)

YEPHKFLGSGSFSGVWECQHMTTGESVACKVIDINTAISDQVYYHFRNELLIHSKIHHSSITQLKDIIIDKDNIYIFIELCDG--GDLNDIVQDVGG---
|| .. .|.|.|. |. |.|  ||. ||.|.|.           |.|.|. |..| ||  | .|.|.. | |..|.. |.|||  ||| |. .. |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTEQEAKHYFHQIIDALSYIHKLGVAHRDVKLENILITADDDAKLTDFGLCKQQRGNDPMLTTCGTLVYAAPEIIREEPYNGMKADIWSAGIVLYAM
   ..| .|..|..||..|| |.|..|. |||.| ||||..     |..||||..|        | |||. | |||..   .|.. |.|.|| |..|| |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

IAAHFPWVVPDDLPPDILMKETAKQIASGDIILPDGISYELQNLLGNMLNVDPEERPTADEILQ-------HPWF
..   |.           |... |.|           | |. ... ..|..|||.|||| |.||       ||||
LCGYPPFP---------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81840.m00166.AA Pkinase 7-266 34 3.7e-89 307.3 Pfam 1-293 (293) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-293/293
Sequence Identity: 34% (102 aa)

YEPHKFLGSGSFSGVWECQHMTTGESVACKVIDINTAISDQVYYHFR-NELLIHSKIHHSSITQLKDIIIDKDNIYIFIELCDGG----DLNDIVQ--DV
|. .. .|||||. |..|.|  ||. ||.|.|.  .. |.. ..|.| .|. |. ...|  | .|.|.  |||.||.  |.|.||    || |...  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GGL--TEQEAKHYFHQIIDALSYIHKLGVAHRDVKLENILITADDDA----KLTDFGLCKQ--QRGNDPMLTTCGTLVYAAPEIIREEPYNGMKADIWSA
|..  .|.|.|.|. ||. .| |.|. |. |||.|.|||||  ...     |..||||.||     |  | | |||. |.|||.||. .| | |.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIVLYAMIAAHFPWVVPD-DLPPDILMKETAKQIASGDIILPDGIS---------------------YELQNLLGNMLNVDPEERPTADEILQHPWF
|..|| |.  ..|.   . . .. . ...  ..| ....  .   .                      |.. .. ..|..||..||||..|||||||
GCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81840.m00166.AA MARK 7-266 36 3e-81 265.36 In-house 1-262 (262) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-262/262
Sequence Identity: 36% (98 aa)

YEPHKFLGSGSFSGVWECQHMTTGESVACKVID---INTAISDQVYYHFRNELLIHSKIHHSSITQLKDIII--DKDN-IYIFIELCDGGDLNDIVQDV-
|.  | .| ||.. |  ..|  ||. || |...   .|   . .    .. |. |..|..|  |..| ..|   .. . ||.  |.. ||.| | .. . 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKN---VMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHP

-GGLTEQEAKHYFHQIIDALSYIHKLGVAHRDVKLENILITADD--DAKLTDFGLCKQQRGNDPMLTTCGTLVYAAPEIIREEPYNGMKADIWSAGIVLY
 | |.| ||...|.||. |..| |. ...||| |.||||| ..   ..|..|||.. .   .    | |||. |.||||.  .||.| |.|||| |.|||
NGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLY

AMIAAHFPWVVPDDLPPDIL--MKETAKQIASGDIILPDGISYELQNLLGNMLNVDPEERPTADEILQHPWF
.|.  .||.        .    .||  |.| .|.   |. .| |..||.  .|.|.||||||..||..|||.
FMVCGYFPFD-------GDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 81840.m00166.AA AMPK 7-266 35 2e-77 229.46 In-house 1-254 (254) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-254/254
Sequence Identity: 35% (92 aa)

YEPHKFLGSGSFSGVWECQHMTTGESVACKVIDINTAISDQVYYHFRNELLIHSKIHHSSITQLKDII-IDKDNIYIFIELCDGGDLNDIVQDVGGLTEQ
|   | .| |.|  |    | .||| || |...    .....    ..|. |  .. | .|.|| ..|   .. |....|   ||.| | .   | |.|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EAKHYFHQIIDALSYIHKLGVAHRDVKLENILITADDDAKLTDFGLCKQQRGNDPMLTTCGTLVYAAPEIIREEPYNGMKADIWSAGIVLYAMIAAHFPW
||. .| ||| ...|.|.....||| |.||.|. ..   |. |||| .    ..   | ||   |||||.|   .|.| . |||| |..||||. .  | 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

VVPDDLPPDILMKETAKQIASGDIILPDGISYELQNLLGNMLNVDPEERPTADEILQHPWF
   ||     |     | | .|.  .|. .| | ..|. .||.|||..| | ..| .||||
---DDENTPTLY----KKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 81840.m00166.AA Ciliate-E2 7-266 24 7e-73 248.44 In-house 1-365 (365) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-365/365
Sequence Identity: 24% (94 aa)

YEPHKFLGSGSFSGVWECQHMTTGESVACKVIDINTAISDQ-------------VYYHFRNELLIHSKIH----------------------HSSITQLK
|. .| .|.|.|. |..|..  ... .| |.|| .   ..|              ... ..   | ..||                      |  | ...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

DIII--DKDNIYIFIELCDGGDLNDIVQ------------DVGGLTEQEAKHYFHQIID---------------ALSYIHKLG-VAHRDVKLENILITAD
.  .  |..|||.  |.|.|||| |. .            | . .||.|.|... ||..               || |.|. . . ||| |.||||.   
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---

DDAKLTDFGLCK------------QQRGNDPMLT---------------------TCGTLVYAAPEIIREEPYNG--------MKADIWSAGIVLYAMIA
   |..||||.|            ||... .                        .|||. | ||||.. ..|..         |.||||.|..|| |. 
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

AHFPWVVPDDLPPDILMKETAKQIASGDIILP------------------DGISYELQNLLGN----MLNVDPEERPT-ADEILQHPWF
  .|.                .||  ..| .|                  . .| | ..|. .    ||..|||.|.| ...||.||||
GKPPF---------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 81840.m00166.AA Ciliate-E2-Unclassified 7-266 23 1.3e-71 244.19 In-house 1-352 (352) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-352/352
Sequence Identity: 23% (85 aa)

YEPHKFLGSGSFSGVWECQHMTTGESV-----ACKVIDINTAISDQVYYHFRNELLIHSKIH-------------------HSSITQLKDIIIDKDNIYI
|. .| .|.|.|. |..|||  ..  .     ..|.....  .  ..   . ||...  ..                    |  |  . ..  ||.||||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

FIELCDGGDLNDIVQDVGG-----------------LTEQEAK-----HYFHQIIDALSYIHKLG-VAHRDVKLENILITADD---DAKLTDFGLCK---
  |.|.|||| .. .. ..                 .|||.||     .|| ||...|.|.|. . . ||| |.||||.. .      |..|||..|   
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

---QQRGNDP-----------MLTTCGTLVYA----APEIIREEPYNGM---KADIWSAGIVLYAMIAAHFPWVVPDDLPPD-------------ILMKE
   ... ..            | |.|||. |     |||..... |...   |.|||| |..||.|.   .|   ...   .             .| ..
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

TAKQIASGDIILP----DGISYELQNLLG----NMLNVDPEERPTADEILQHPWF
  ... . .   .    ...| | ....      ||...|..|.|...||.||||
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 81840.m00166.AA ULK 7-266 27 2.1e-66 226.95 In-house 1-324 (324) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-324/324
Sequence Identity: 27% (90 aa)

YEPHKFLGSGSFS-GVWECQHMTT---GESVACKVIDIN-TAISDQVYY------HFRNELLIHSKIH------HSSITQLKDIIIDK--DNIYIFIELC
|. .. ||.|||   | .  .. |   .. ||||.||..   .. . ..       ..||  |  |..      |  | .|.|.  ..  .||||. |.|
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC

DGGDLNDIVQDVGG---------LTEQEAKHYFHQIIDALSYIHKLGVAHRDVKLENILITADDD------------AKLTDFGLCKQ-Q---RGNDPML
.|||| .. .  ..         |.||||...|.||. .. ..|| .. ||| |..||||. ..             .|..|||..|. .      . . 
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

TTC------GTLVYAAPEIIR----EEPYNGMKADIWSAGIVLYAMIAAHFPWVVPDDLPPDILMKETAKQ-------IASGDIILPD-----GISYELQ
|..      ||  | ||.|.     ..||.  |.|||| |...| |.    |.. .   . .. ...  ..       |    |  |.      || |..
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

NLLGNMLNVDPEERPTADEILQHPWF
.|.  || .|...| . .||..||||
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 81840.m00166.AA ULK 7-266 28 7e-66 225.19 In-house 1-329 (329) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-329/329
Sequence Identity: 28% (94 aa)

YEPHKFLGSGSFSGVWECQHMTT----GESVACKVIDINTAISDQVYYH-------FRNELLIHSKIH--------HSSITQLKDIIIDK--DNIYIFIE
|. .. ||.|||  | .  .. |    .| ||||.||... . ..  .        ..||  |  |..        |  | .|.|.  ..  .||||. |
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCDGGDLNDIVQDVGG----------LTEQEAKHYFHQIIDALSYIHKLGVAHRDVKLENILITAD----DD--------AKLTDFGLCKQ-QRG---ND
.|.|||| .. .  ..          |.||||...|.||. .. ..|| .. ||| |..||||. .    |.        .|..|||..|. . .   ..
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

PMLTTC------GTLVYAAPEIIR----EEPYNGMKADIWSAGIVLYAMIAAHFPWVVPDDLPPD--ILMKETAK------QIASGDIILPDG-----IS
 |.|.       ||  | ||.|.     ..||.  |.|||| |...| |.    |.. .   . .  |..|.  .      || .  .  |.      ||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

YELQNLLGNMLNVDPEERPTADEILQHPWF
 |...|.  || .|...| . .|...||||
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 81840.m00166.AA TSSK 7-266 29 4.4e-63 205.87 In-house 1-289 (289) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-289/289
Sequence Identity: 29% (87 aa)

YEPHKFLGSGSFSGVWECQHMTTGES----------------VACKVIDINTAISDQVYYHFRNELLIHSK-IHHSSITQLKDIIIDKD-NIYIFIELCD
|.  | .|.||.. | .......                   ||.|.||.  | .| .   .  |. |  | ..|..| |.  ..   .  ||.. |...
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

GGDLNDIVQDV------GGLTEQEAKHYFHQIIDALSYIHKLGVAHRDVKLENILITADDDAKLTDFGLCKQQRGNDP-----MLTT-CGTLVYAAPEII
.||| . .|..      |.|.|..|.  |.|...|. |.| ..|.|||.|.||||   .   ||||||  . .  .||     ...| ||   ||||||.
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

REEPYNGMKADIWSAGIVLYAMIAAHFPWVVPDD--LPPDILMKETAKQIASGDIILPDGISYELQNLLGNMLNVDPEERPTADEILQHPWF
|  ||.....|.|| |..||.|  .. |    ||    .  .....  . .. .. .  .|| | ..|.  ||  .| .||...||. |.| 
RGIPYDPKWYDVWSMGVILYIMVCGCMPF---DDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase 81840.m00166.AA MELK 7-266 37 2.1e-60 205.06 In-house 1-254 (254) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-254/254
Sequence Identity: 37% (98 aa)

YEPHKFLGSGSFSGVWECQHMTTGESVACKVIDINTAISDQVYYHFRNELLIHSKIHHSSITQLKDIIIDKDNIYIFIELCDGGDLNDIVQDVGGLTEQE
|| |. .|.| |. |    |. |.. || |..| |.  .|      . |.    ...|  | ||  .|  .| |.. .| | ||.. | .     | |.|
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGHD--LPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEE

AKHYFHQIIDALSYIHKLGVAHRDVKLENILITADDDAKLTDFGLCKQQRGNDPML---TTCGTLVYAAPEIIREEPYNGMKADIWSAGIVLYAMIAAHF
..|.| ||. |..|.|  | ||||.| ||.|.. |   || ||||| . .|.       | || . |||||.|.   | |  ||.|| ||.||...    
TRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PWVVPDDLPPDILMKETAKQIASGDIILPDGISYELQNLLGNMLNVDPEERPTADEILQHPWF
|.   ||    |.     |.| ||    |. .| | ..|| .|| |||. |    ..|.||| 
PF---DDDNMMIMY----KKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 81840.m00166.AA TyrKc 7-266 21 8.8e-15 16.29 SMART 1-280 (280) Show / Hide 
Range on Protein: 7-266
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YEPHKFLGSGSFSGVWECQHMTTGESVACKVIDINTAISDQVYYHFRNELLIHSKI--HHSSITQLKDIIIDK-------DNIYIFIELCDGGDLNDIVQ
 .  | ||.| |  |....     . || |..  ..         |..|. | .|.  ||  | .|  .....       . ..|  |....|||.|  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

DVGG-LTEQEAKHYFHQIIDALSYIHKLGVAHRDVKLENILITADDDAKLTDFGLCKQQRGN------DPMLTT----CGT--LVYA--APEIIREEPYN
. .. |. ..  .. .|| .  .|.|. .. |||    |.|....  .| .||||..           . . ..    .|   | .   ||| |..  ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GMKADIWSAGIVLY---AMIAAHFPWVVPDDLPPDILMKETAKQIASGDII-LPDG--------ISYELQNLLGNMLNVDPEERPTADEILQHPWF
  | |.|| |....      .   | ..      ..  .|  ... .|.    |.          . |. ..     . |||.|||  ||  |  |
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQ----MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 81840.m00166.AA Pkinase_Tyr 7-153 26 2.3e-09 32.33 Pfam 1-159 (270) Show / Hide 
Range on Protein: 7-153
Range on HMM: 1-159/270
Sequence Identity: 26% (43 aa)

YEPHKFLGSGSFSGVWECQHM----TTGESVACKVIDINTAISDQ-VYYHFRNELLIHSKI-HHSSITQLKDIII-DKDN--IYIFIELCDGGDLNDIVQ
 .  | ||.|.|  |...        |.  || |..  ..| ..|     | .|. | ... ||  | .|  ... ...   |||  |.. .||| |  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

D----VGGLTEQEAKHYFHQIIDALSYIHKLGVAHRDVKLENILITADDDAKLTDFGLCK
.     . || ..  .. .|| ....| .  .  |||.   |.|.| .  .| .||||..
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR