Gene 91452.m00060 (T.vaginalis)

91452.m00060

Species: T.vaginalis
Alias: TvagK0091, 91452.m00060
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
91452.m00060.AA Protein None 261 None Fasta, JSON
91452.m00060.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 91452.m00060.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 91452.m00060.AA CAMKL 11-261 36 1.4e-102 328.15 In-house 1-295 (297) Show / Hide 
Range on Protein: 11-261
Range on HMM: 1-295/297
Sequence Identity: 36% (110 aa)

YELKTVIGEGGFAQVFLAKH-LPSNSDVAIKVIPKNVAN-EPDHLKY-----------INKEIQILREIK---HPFICGLYEVLESSEY------LYIVL
|..  ..|.|.|..| ||.| .  .  ||||.| |. .. .|  .|            | .||||.. ..   || |. ||||.| .|.      .|.|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYLENGT--LLDEINLN----GPLKERDSAIVFAEIMLALKYLHTKVHIVHRDLKAENVLYDGNH--NIRIIDFGFGKEMDP-----DQYFQTQCGSLFY
|| ..|   |.| |  .    |...|..    |  |. |..|.| .  |||||.|.||.| | |.  || ||||||. ...|     .| . |.|||. |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

AAPEIIQG--QKYS-YSVDIWSAGILLFALNSGFLPFDDQ--------NLAKLAQKIIYQEVTYPAYFSV-SLRDLLTKMLNKDPVQRPCVDEILQHP
.||||.||  ..|  . |||||.|..|.|.  | |||||.        |  .|  ||. .   .| ...| ..|||. |||...| .|| ...|..||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHP
Kinase 91452.m00060.AA CAMK 16-261 23 2e-98 317.79 In-house 1-423 (425) Show / Hide 
Range on Protein: 16-261
Range on HMM: 1-423/425
Sequence Identity: 23% (101 aa)

VIGEGGFAQVFLAKHLPSN------------SDVAIKVIPKNVANE-------------------------PDHLKYINKEIQILRE-------IKHPFI
..|.|.|..|.|..|  ..              ||||.|.|. . .                         |  .| . .||.|..        ..|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

CGLYEVLESSEY-------------------LYIVL---EYLENG----TLLDEINLNGP---------------LKERDSAIVFAEIMLALKYLHTKVH
. |||| |...|                   .|.|.   || ..|     |.| |  .|.               ..||. . .|  |  |..|.| .  
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-

IVHRDLKAENVLYDGNH-----------------NIRIIDFGFGKEMDP------------------------DQYFQTQCGSLFYAA-PEIIQG-----
||||||| ||.|.| |.                 || |||||| ...||                        .| ..|.||.. |.| ||...|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------QKYSYSVDIWSAGILLFALNSGFLPFDDQ-------------NLAKLAQKIIYQEVT-YPAYFSV-----------------------SLR
         . |....|.||.|..|... .|..||..              |. .| .||.  . . .| |||                        . .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLLTKMLNKDPVQRPCVDEILQHP
||. |||..|| .|. ....|.||
DLIRKMLQVDPEKRMTIEQCLNHP
Kinase 91452.m00060.AA AGC 11-261 23 5.8e-98 253.24 In-house 1-393 (395) Show / Hide 
Range on Protein: 11-261
Range on HMM: 1-393/395
Sequence Identity: 23% (92 aa)

YELKTVIGEGGFAQVFLAKHL------PSNSDVAIKVIPKNV---ANEPDHLKYINKE------------IQILREIK----------HPFICG-LYEVL
.|...|||.|.| .|.|...        ..   |.||. | .    .. . ..... |             .|| ...          ||||.  |.   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ESSEY--LYIVLEYLE---------NG-TLLDEIN---LNGPLKERDSAIVFAE-------IMLALKYLHTKVHIVHRD-LKAENVLYDGNHNIRIIDFG
.. ..  ||.|.||..          |  |.  .     .| . |  . . .||       | ||| ||| . .|.||| || ||.| | . .|.. |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FGKEMDPD---------------------------------------------------QYFQTQCG--SLFYAAPEIIQGQKYSYSVDIWS--AGILLF
. ||.  |                                                   .  .| ||  .  | ||||.    |....|.||   |.|..
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ALNSGFLPFDDQNLA----------KLAQKII------YQEVTYP----------AYFSVSLRDLLTKMLNKDPVQRPC----------VDEILQHP
 . .|  || ..|            .. |||.       ..|..|           .||. ..||..|.|.||| .|.           ..|| .||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHP
Kinase 91452.m00060.AA MARK 11-261 37 9.1e-96 313.5 In-house 1-260 (262) Show / Hide 
Range on Protein: 11-261
Range on HMM: 1-260/262
Sequence Identity: 37% (98 aa)

YELKTVIGEGGFAQVFLAKHLPSNSDVAIKVIPKNVANEPDHLKYINKEIQILREIKHPFICGLYEVLE--SSEY-LYIVLEYLENGTLLDEINLN--GP
|.....||.|..|.| || |....  ||||...|.  |.|  .| .  ||.|.. ..|| |  |..| |   ..  .|...|| ..| |.| |     |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LKERDSAIVFAEIMLALKYLHTKVHIVHRDLKAENVLYDGNH--NIRIIDFGFGKEMDPDQYFQTQCGSLFYAAPEIIQGQKYS-YSVDIWSAGILLFAL
|.|..    |  |  |..|.| |  |||||.|.||.| | |   || ||||||. .  |.|   | ||.. |.||||.....|  . ||||| |..|...
LHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

NSGFLPFDDQN--LAKLAQKIIYQEVTYPAYFSVSLRDLLTKMLNKDPVQRPCVDEILQHP
 .| .|||...  . .| .||   . ..| . |...|.|. ..|. .| .|| ..||..||
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHP
Kinase 91452.m00060.AA AMPK 11-261 41 4.5e-93 276.66 In-house 1-252 (254) Show / Hide 
Range on Protein: 11-261
Range on HMM: 1-252/254
Sequence Identity: 41% (104 aa)

YELKTVIGEGGFAQVFLAKHLPSNSDVAIKVIPKNVANEPDHLKYINKEIQILREIKHPFICGLYEVL-ESSEYLYIVLEYLENGTLLDEINLNGPLKER
| ..  |||| |  | ...|   . .||||.. |    . |  . | .||.||. ..|| |  ||||. |. . ...|.||  .| | | |  .| |.||
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

DSAIVFAEIMLALKYLHTKVHIVHRDLKAENVLYDGNHNIRIIDFGFGKEMDPDQYFQTQCGSLFYAAPEIIQGQKY-SYSVDIWSAGILLFALNSGFLP
... .|. |  .. |.| .  ||||||| ||.| | |.|| | |||  . |   ..  | |||  |||||.|.|..| .  ||||| |. |.|.  | ||
EACRFFQQIISGVEYCH-RHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

FDDQNLAKLAQKIIYQEVTYPAYFSVSLRDLLTKMLNKDPVQRPCVDEILQHP
|||.| ..| .||. .|.. |...| . .||. .||..||..|  ...| .||
FDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHP
Kinase 91452.m00060.AA S_TKc 11-261 32 1.8e-91 311.1 SMART 1-229 (231) Show / Hide 
Range on Protein: 11-261
Range on HMM: 1-229/231
Sequence Identity: 32% (88 aa)

YELKTVIGEGGFAQVFLAKHLPSNSDVAIKVIPKNVANEPDHLKYINKEIQILREIKHPFICGLYEVLESSEYLYIVLEYLEN--GTLLDEINLNGP---
||.  .||.|.|..|....|  ..  ||||.|.          . | .|||||.. .||.|. ||.| .. ..||.|.||...  |.|.| |  .|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LKERDSAIVFAEIMLALKYLHTKVHIVHRDLKAENVLYDGNHNIRIIDFGFGKEMDPDQYFQTQCGSLFYAAPEIIQGQKYSY-SVDIWSAGILLFA
   . | . . ....| .||.|.| . .|.||||| ||.| |   .| |.|||. ...       |.||...| |||..   .|.. ..|.|| |..|. 
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LNSGFLPFDDQNLAKLAQKIIYQEVTYPAYFSVSLRDLLTKMLNKDPVQRPCVDEILQ-------HP
. .|  ||.  ..... .||           | ...|.. |.|.||| .|| . |.||       ||
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHP
Kinase 91452.m00060.AA Pkinase 11-261 29 8.4e-82 282.86 Pfam 1-291 (293) Show / Hide 
Range on Protein: 11-261
Range on HMM: 1-291/293
Sequence Identity: 29% (87 aa)

YELKTVIGEGGFAQVFLAKHLPSNSDVAIKVIPKNVANEPDHLKYIN-KEIQILREIKHPFICGLYEVLESSEYLYIVLEYLENG----TLLDEIN--LN
|... .||.|.|..|....|  ..  ||.|.|.|  ...  .   ..  ||||.....||.|. ||.. |.. ..|.|.||.|.|     | | |    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPL--KERDSAIVFAEIMLALKYLHTKVHIVHRDLKAENVLYDGNHNI----RIIDFGFGKE--MDPDQYFQTQCGSLFYAAPEIIQ-GQKYSYSVDIWS
|..   |..   .. .|  .|.|.| .  |.||||| ||.|.| | .|    .|.|||. |     ... ..| ||...|.|||.|. ||.|...||.||
GCFYFSEWECKFYMYQILRGLEYCHSM-GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

AGILLFALNSGFLPFDDQ------NLAKLAQKIIYQEVTYPAYFS---------------------VSLRDLLTKMLNKDPVQRPCVDEILQHP
.|..|. . .| .||...      .  .. ..| . .. .. . .                      ...|.....|.||| .||  ..|||||
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP
Kinase 91452.m00060.AA Ciliate-E2 11-261 25 1.7e-77 263.78 In-house 1-363 (365) Show / Hide 
Range on Protein: 11-261
Range on HMM: 1-363/365
Sequence Identity: 25% (96 aa)

YELKTVIGEGGFAQVFLAKHLPSNSDVAIKVIPKNV------------------ANEPDHLKYINKEIQILREIK----------------HPFICGLYE
|..  .||.|.|..|...|.   . ..|||.|  .                    .... ...|..||.|.|||.                ||.|. .||
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VLE--SSEYLYIVLEYLENGTLLDEINLN-----------GPLKERDSAIVFAEIML---------------ALKYLHTKVHIVHRDLKAENVLYDGNHN
. .  . ...|.|.||.. |.|.| |. |           ....|.  . ....|                 ||.||| | .|.|||.| ||.|.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IRIIDFGFGKEMDPD--------------------------------QYFQTQCGSLFYAAPEIIQGQK---------YSYSVDIWSAGILLFALNSGFL
| |||||. |. |.|                                . |.|.||.. | ||||..|.|         |.|..||||.|..|. . .| .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFDDQNLAKLAQKIIYQEVTYP----------------AYFSVSLR--DLLTK----MLNKDPVQRPC-VDEILQHP
||         |.|. ... .|                 ....|.   ||. |    ||.||| .|.   ..||.||
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHP
Kinase 91452.m00060.AA QIK 11-261 37 9e-77 261.36 In-house 1-270 (272) Show / Hide 
Range on Protein: 11-261
Range on HMM: 1-270/272
Sequence Identity: 37% (102 aa)

YELKTVIGEGGFAQVFLAKHLPSNSDVAIKVIPKNVANEPDHLKYINKEIQILREIKHPFICGLYEVLESSEYLYIVLEYLENGTLLDEINLNGP-----
|..   || | || | ||.|    . ||||.| |   .| . |. .  |.||.  ..||.|  ||.|.|. ...||| || .|| . | .. .|      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDE-ENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LKERDSAIVFAEIMLALKYLHTKVHIVHRDLKAENVLYDGNHNIRIIDFGFGKEMDPDQYFQTQCGSLFYAAPEIIQGQKYS-YS
               ..|.. . .| .|..| .|.| . .||||||||||.| | | || |.||||.    ..|  .| |||  |||||. .|..|    
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKR-NIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK

VDIWSAGILLFALNSGFLPFDDQNLAKLAQKIIYQEVTYPAYFSVSLRDLLTKMLNKDPVQRPCVDEILQHP
||||| |..|..| .| |||| ..| .| |...   .  | . |. . .|  .||  || .|  .. |.||.
VDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHR
Kinase 91452.m00060.AA RSK 14-261 31 2.7e-71 243.15 In-house 1-276 (278) Show / Hide 
Range on Protein: 14-261
Range on HMM: 1-276/278
Sequence Identity: 31% (86 aa)

KTVIGEGGFAQVFLAKHL---PSNSDVAIKVIPKNVANEPDH-LKYINKEIQILREIK-HPFICGLYEVLESSEYLYIVLEYLENGTLLDEINLNGP---
  | |.||.  ||| .      ..   | ||. |...   .  ...  .|..|| ... ||||. |... .  ..||...||.. | |.. .   .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LKERDSAIVFAEIMLALKYLHTKVHIVHRDLKAENVLYDG---NHNIRIIDFGFGKEMDPD--QYFQTQCGSLFYAAPEIIQ---GQK-YSYSVDIWSAG
. |.. ....||| ||...||..  |.||||| ||.|||    .  |...|||| |....|  |  .| |... |.|||..    .|. .. ..|.|| |
FSEDEACFYMAEIVLAVEHLHQQG-IIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

ILLFALNSGFLPFDD---QNLAKLAQKIIYQE--VTYP--AYFSVSLRDLLTKMLNKDPVQRPC-----VDEILQHP
.|.. . .|..||     .| ... ..|   .  .| |  .| |   .||..||| .|| .|.      ..||.|||
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHP
Kinase 91452.m00060.AA Ciliate-E2-Unclassified 11-261 26 6.2e-71 241.97 In-house 1-350 (352) Show / Hide 
Range on Protein: 11-261
Range on HMM: 1-350/352
Sequence Identity: 26% (92 aa)

YELKTVIGEGGFAQVFLAKHLPSNSDV-----AIKVIPKNVANEPD---------HLKYIN--------KEIQ-ILREIKHPFICGLYEVLESSEYLYIV
|..  .||.|||..|....|   .  .     ..|.. ... .            ... ..        |. | ||. ..||||  .... .. ...|||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LEYLENGTLLDEINLNGP-----------------LKERDSA-----IVFAEIMLALKYLHTKVHIVHRDLKAENVLYDGNH---NIRIIDFGFGKEMD-
.||.|.|.|.. |. ..                  . |. ..       ||.| ..|.||| | .|.|||.| ||.|.| |.   .|.|||||. |. . 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------PDQYFQTQCGSLFYA----APEIIQGQKYS----YSVDIWSAGILLFALNSGFLPFDDQNLAK----------------LAQKII
               ..| ..|.||.. |     |||..|||.|.    |..|||| |..|...  | .||.|.|  .                | |.|.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

YQEVTYPA--------YFSVSLRDLLT----KMLNKDPVQRPCVDEILQHP
 ... .|           | .  |...    |||.|.| .|.  ..||.||
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHP
Kinase 91452.m00060.AA ULK 11-261 28 3.6e-66 226.15 In-house 1-322 (324) Show / Hide 
Range on Protein: 11-261
Range on HMM: 1-322/324
Sequence Identity: 28% (92 aa)

YELKTVIGEGGFA-QVFLAKHLPS---NSDVAIKVIPKN-VANEPDH------LKYINKEIQILREIK---HPF--ICGLYEVLESS--EYLYIVLEYLE
|.|. ..|.| |. .|. ...  .   | .||.|.|.|.   . .        .. ...||||....|   ||.  |. ||...|.|   ..||..|| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGTLLDEINLNGPLKERD----------SAIVFAEIMLALKYLHTKVHIVHRDLKAENVL--YDGNHN----------IRIIDFGFGKEMDPD----QYF
 |.| . |. |..|.|              ..|  |. ..|.|| |  |.|||.| .| |   .  ..          . | ||||.|  | .    | .
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELH-KHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMC

QTQC------GSLFYAAPEIIQ----GQKYS-YSVDIWSAGILLFALNSGFLP----FDDQNLA--KLAQK-------IIYQEVTYPAY-----FSVSLR
||..      |.  | ||.|.|    ...|. | .|||| |.... .  |  |    | ||.|   || ..       | .| . .| .     .|  ..
QTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

DLLTKMLNKDPVQRPCVDEILQHP
||. .|| .|. .|   .||..||
DLIRRMLQYDEKDRISWEEIFNHP
Kinase 91452.m00060.AA TyrKc 11-261 23 5.8e-18 66.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 11-261
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YELKTVIGEGGFAQVFLAKHLPSNSDVAIKVIPKNVANEPDHLKYINKEIQILREI--KHPFICGLYEVLESS-------EYLYIVLEYLENGTLLDEIN
 .|. ..||| | .|....      .||.|.. ..       .. . .|..|....  .|| |  || |  ..       | |.||.|| ..| |.| . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

LNGP-LKERDSAIVFAEIMLALKYLHTKVHIVHRDLKAENVLYDGNHNIRIIDFGFGKEMDPD-------QYFQTQ---CGS----LFYAAPEIIQGQKY
 ..| |. .|       |     ||| | ...|||| | |.|.. || ..| |||  .. . |       .|  ..   .|     .   ||| |.  |.
KHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

SYSVDIWSAGILLF-ALNSGFLPFDD-----QNLAKLAQKIIYQEVTY-PAY--------FSVSLRDLLTKMLNKDPVQRPCVDEILQHP
.   |.|| |....  .  |  |  .      . . . ...   .    |..         .  . .. ..  . || .||.  || .  
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 91452.m00060.AA Pkinase_Tyr 11-98 28 3e-12 42.11 Pfam 1-96 (270) Show / Hide 
Range on Protein: 11-98
Range on HMM: 1-96/270
Sequence Identity: 28% (28 aa)

YELKTVIGEGGFAQVFLAKHL----PSNSDVAIKVIPKNVANEPD--HLKYINKEIQILREI-KHPFICGLYEVLE-SSEY--LYIVLEYLENGTLLD
 ..  ..||| | .|....        . .||.|.. |. | ...  . . .. |..|.... .|| |  || |    .|   .|||.|| ..| |||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD
Kinase 91452.m00060.AA Pkinase_Tyr 121-200 32 0.000204 15.58 Pfam 123-205 (270) Show / Hide 
Range on Protein: 121-200
Range on HMM: 123-205/270
Sequence Identity: 32% (27 aa)

ALKYLHTKVHIVHRDLKAENVLYDGNHNIRIIDFGFGKEMDPDQYF-QTQC---GSLFYAAPEIIQGQKYSYSVDIWSAGILLF
.. ||. | ...|||| | |.| . |. ..| |||  . . .| |  ...       .  ||| |.  |..   |.|| |.|..
GMEYLESK-NCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMW