Gene 84774.m00068 (T.vaginalis)

84774.m00068

Species: T.vaginalis
Alias: 84774.m00068, TvagK0717
External Links:
Annotation:

Classification

Group: CMGC
Family: CK2

Sequence

Name Sequence Type Origin Length Description Download
84774.m00068.AA Protein None 340 None Fasta, JSON
84774.m00068.kin_dom Protein Kinase Domain None 282 None Fasta, JSON

Protein domain

Protein domains of 84774.m00068.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84774.m00068.AA CK2 50-331 54 1.7e-147 443.84 In-house 1-288 (288) Show / Hide 
Range on Protein: 50-331
Range on HMM: 1-288/288
Sequence Identity: 54% (158 aa)

YEILDRIGSGKYSDVFTAYKGKEIV----AIKILKPTRDVKFLREAKILIDLRGGPNIVNLYDVVYTPLTNQYSFVFEYIPELKWQDLFASMTDYEARVY
||.  .||.||||.|| ... |        |||||| .  |  || ||| .|.|||||..|||.|  |     . ||||. .  .. |.  .|||. | |
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY

LYQLLRTLDYAHSHGIMHRDVKPLNILFDKKTYKLRLIDWGLADFYHPGQNYQIHVATRYYKPPELLLDYQKYDYSVDMWCFGVTMASLVFKIYPFFRGS
...||..|||.|| ||||||||| ||. | .  ||||||||||.||||||.| . ||.||||.||||.||| ||||.||| .|. .||..||  |||.|.
MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGH

DDFDMISKISSVLGTDGLSEYLDKYGIPLPPNIHV--YKSKRKPWWSFVNGENASLANEDAIDLLDKCIVYDHTERITAKEAMAHRYF
|  |   ||  ||||. | .|||||||.|.|..|    . |.|||  |.. ||  ||...|||.|||  .|||.||||||||| | ||
DNYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQFHDIMQQHKKKPWERFIHQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase 84774.m00068.AA CMGC 50-331 21 1.2e-85 281.26 In-house 1-513 (513) Show / Hide 
Range on Protein: 50-331
Range on HMM: 1-513/513
Sequence Identity: 21% (109 aa)

YEILDRIGSGKYSDVFTAYK----------------GKEIVAIKILK-PTRDVKF--------------LREAKILIDLR----------------GGPN
|||...||.| |. |. ..                 ..||||||..| |  .                 ||| |||  |.                  .|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVNLYDVVYTPLTN---------------QYSFVFEYIPE--LKWQDLFA---------SMTDYE------------ARVYL------YQLLRTLD--YA
||.|||..|.. ..               .  .||||..   ..  .             ... .             . ..      ||.|| |.  | 
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSHG--IMHRDVKPLNILFDKKT-------------------YKLRLIDWGLADFYHPGQN----------------------YQIHVATRYYKPPELLL
|||.  |.||| || |||.....                   ..|...|.||| .||| ..                      |   |.||.|..||.||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

DY---------QKYDYSVDMWCFGVTMASL-------VFKIYPFFR-----------GSDDFDMISKISSVLGTDG---------------LSEYLDKYG
 .         ..|....||| .|  .| .       .|. .|.|            |... |.. ||  ||||                   |. .. .
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

IPLPPNIHV---------YKSKR----------KPWWSFVNGEN------------------------------------ASLANEDAIDLLDKCIVYDH
 |  ..            ..|.           .||| . . .|                                     ......|||||.|. .||.
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

TERITAKEAMAHRYF
..||||..|..| ||
DKRITAEQALQHPYF
Kinase 84774.m00068.AA S_TKc 50-331 27 2.8e-68 234.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 50-331
Range on HMM: 1-231/231
Sequence Identity: 27% (83 aa)

YEILDRIGSGKYSDVFTAYKGK--EIVAIKILKPTRDVKFLREAKILIDLRGGPNIVNLYDVVYTPLTNQYSFVFEYIP----ELKWQDLFAS-------
||||. ||.| .. |. ... |  .||||||.|     ...|| .||    . ||||.|||| ..   . . .|.||..    .|..             
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

MTDYEARVYLYQLLRTLDYAHSHGIMHRDVKPLNILFDKKTYKLRLIDWGLADFYHPGQNYQIHVATRYYKPPELLLDYQKYDY-SVDMWCFGVTMASLV
..  .|| |.||... |.| |||||.|||.|| |||.|.    . ..| ||| ..         . |..| .||.|    .|.. ..|.| .|.... ..
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

FKIYPFFRGSDDFDMISKISSVLGTDGLSEYLDKYGIPLPPNIHVYKSKRKPWWSFVNGENASLANEDAIDLLDKCIVYDHTERITAKEAMA-------H
    ||    ... |. ||                                               ..|.|...|| ..| ..|.|| ||..       |
CGYPPFP---QMQMMFKKIG---------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCH

RYF
 .|
PWF
Kinase 84774.m00068.AA Pkinase 50-331 26 7.7e-68 236.48 Pfam 1-293 (293) Show / Hide 
Range on Protein: 50-331
Range on HMM: 1-293/293
Sequence Identity: 26% (84 aa)

YEILDRIGSGKYSDVFTAYKGKE--IVAIKILKPTRDVKFLR-------EAKILIDLRGGPNIVNLYDVVYTPLTNQYSFVFEYIPE-LKWQDLF-----
|.|. .|||| .. |. ... ..  |||.||.|  .. .  .       |..|.  | . |||| |||....   . . .|.|| .  |. .|||     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

------ASMTDYEARVYLYQLLRTLDYAHSHGIMHRDVKPLNILFDKKTYK---LRLIDWGLADF--YHPGQNYQIHVATRYYKPPELLLDYQKYDYSVD
        ... |.. |.||.|| |.| ||.||.|||.|| |||.|.. .    ....|.||| .  | ... ..  . |..| .||.....|.|...||
WRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

MWCFGVTMASLVFKIYPFFRGS----DDFDMISKISSVLGTDGLSEYLDKYGIPLPPNIHVYKSKRKPWWSFVNGENASLANEDAIDLLDKCIVYDHTER
|| .|.... ....  ||  |.    .  |.. .|  ..|..  ...  .. |.. . .   . .      | . ..  ...|...|....|. .| ..|
MWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H------F-HWTF-HNWSEECKDFIKWCLCKDPKKR

ITAKEAMAHRYF
.||.... | .|
PTAEQILQHPWF
Kinase 84774.m00068.AA CDK 50-260 30 4.5e-48 151.79 In-house 1-243 (284) Show / Hide 
Range on Protein: 50-260
Range on HMM: 1-243/284
Sequence Identity: 30% (78 aa)

YEILDRIGSGKYSDVFTAYKGK-------EIVAIKILKPTRD--------VKF--LREAKILIDLRGGPNIVNLYDVVYTP-LT--------NQYSFVFE
||.|..|| | |  |. |   .       .|||.| ..   .        . .  .|| ..| .|   ||||.|.||..|  .         |  ..|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

YIPE-----LKWQDLFASMTDYEARVYLYQLLRTLDYAHSHGIMHRDVKPLNILFDKKTY----KLRLIDWGLADFYH-------PGQNYQIHVATRYYK
|..      ..             . |..|||| |.| ||..||||| || ||| ...      .| . | |||  ..       | . |   | |. | 
YMDHDLKKYMD------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYR

PPELLLDYQKYD--YSVDMWCFGVTMASLVF--KIYPFFRGSDDFDMISKISSVLGT
.|||||  ..|.   ..||| .|  .| ..      |.| |. . | . ||. ..||
APELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGT
Kinase 84774.m00068.AA Ciliate-E2 50-331 17 2.1e-45 153.82 In-house 1-365 (365) Show / Hide 
Range on Protein: 50-331
Range on HMM: 1-365/365
Sequence Identity: 17% (73 aa)

YEILDRIGSGKYSDVFTA---YKGKEI----------------------VAIKILKPTRDVKFLREAKIL--ID-------------LRGGPNIVNLYDV
|...  ||.| ...|. .    ..|..                      .|.||.|.     ...| .|.  |.             .   |||...|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VYTPLTNQYSFVFEYIPELKWQD------LFA--------SMTDYEARVYLYQLLR---------------TLDYAHSHG-IMHRDVKPLNILFDKKTYK
 ..  .| . .|.||.     .|      ..         ..|..|.. . .|.|.                | | || . |.||| || ||||      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

LRLIDWGLADFYHPGQNYQIH--------------------------------VATRYYKPPELLL--DYQK------YDYSVDMWCFGVTMASLVFKIY
. .||.||. .|.. .....|                                . | .|..|| |   .|..      |||..|.|..||..  ..|. .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFFRGSDDFDMISKISSVLGTDGLSEYLDKYGIPLPPNIHVYKSKRKPWWSFVNGE-------------NASLANEDAIDLLDK----CIVYDHTERIT-
||                                       .. . .  ..| . |             .     ....||. |    ....|  .||| 
PF---------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITG

AKEAMAHRYF
..... | .|
WEQILNHPWF
Kinase 84774.m00068.AA GSK 50-331 29 1.4e-42 127.52 In-house 1-328 (328) Show / Hide 
Range on Protein: 50-331
Range on HMM: 1-328/328
Sequence Identity: 29% (99 aa)

YEILDRIGSGKYSDVFTAYKG------KEI----VAIKILKPTRDVKFLREAKILIDLR--GGPNIVNL---YDVVYTPLTN----QYSFVFEYIPE--L
||. ..||.|  . |. ||        |||    ||||   . . .|  || .|. .|.    ||||.|   ..  |.   .    . ..|.||.|.   
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLVMEYMPQTLY

KWQDLF----ASMTDYEARVYLYQLLRTLDYAHSHGIMHRDVKPLNILFDKKTYKLRLIDWG----LADFY-HPGQNYQIHVATRYYKPPELLLDYQKYD
.  . .      |.... ..| ||..| | | ||||| |||.|| ||| | .| .| . | |    | .   .| . |.    .||| .|||......|.
QVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDTGVLKICDFGSAKQLEPNKNEPNISYIC---SRYYRAPELIFGCTNYT

YSVDMWCFGVTMASLVFKIYPFFRGSDDFDMISKISSVLGTDGL---SEYLDKYGIPLPPNIHVYKSKRKPWWS-------------------FVNGENA
 ..|.| .|  || .. | .|.| | .  |..  |  .|||.     ..   .|     | .   . |..||                     . .  . 
CQIDVWSCGCVMAEML-KGQPLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKPHPWQKNDTKYEYQTYYHKKYRTVYMFKWCHT

SLANEDAIDLLDKCIVYDHTERITAKEAMAHRYF
  .  |.|||. || ||| ..|... ||.|| .|
DMQ--DWIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase 84774.m00068.AA CAMK 55-256 19 1.7e-42 134.32 In-house 1-361 (425) Show / Hide 
Range on Protein: 55-256
Range on HMM: 1-361/425
Sequence Identity: 19% (71 aa)

RIGSGKYSDVFTAYKGKEI--------------VAIKILK-------------------------------PTRDVKFLREAKILIDLRG------GPNI
 .|.| .. |. ..  .                |||||..                               |    ...|| .|.  |.|       |||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNLYDVVYTPL-----------------TNQYSFVF---EYIP--EL--KWQDLFAS------------------MTDYEARVYLYQLLRTLDYAHSHGI
..||.|  .|                  .... .|.   ||..  ||     |   .                  .|  ||| |  |..  ..| |||.|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

MHRDVKPLNILFDKKT----------------YKLRLIDWGLADFYHP------------------------GQNYQIHVATRYYKP-PELLLD------
.||| || |||.|..                 ... .||.|.| .. |                        || ..  . | .| . ||.|.       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------YQKYDYSVDMWCFGVTMASLVFKIYPFFR------------GSDDFDMISKISS
        . |....|||  || .  ..   .||              | .| ..  || .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMK
Kinase 84774.m00068.AA CDC2 50-241 33 1.3e-33 100.23 In-house 1-209 (301) Show / Hide 
Range on Protein: 50-241
Range on HMM: 1-209/301
Sequence Identity: 33% (72 aa)

YEILDRIGSGKYSDVFTA--YKGKEIVAIKILKPTRDVKF-------LREAKILIDLRGGPNIVNLYDVVYTPLTNQYSFVFEYIP-ELK-WQD-LFA--
|. . .|| | |  |. .   . ..|||.|  . ...          .||  .| .|.  |||| | ||..    |    ||||.   ||  .| ..   
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN

-SMTDYEARVYLYQLLRTLDYAHSHGIMHRDVKPLNILFDKKTYKLRLIDWGLA-DFYHPGQNYQ--IHVATRYYKPPELLLDYQKYDYSVDMWCFGVTM
 .|.    . |.||.|. ... |...||||| || ||| |||   ... | ||| .|  |  .|     | |. | .||.||  ..|. .|||| .| ..
KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIF

ASL---VFKIYPF
| .   | | ..|
AEMFMDVTKKPLF
Kinase 84774.m00068.AA CDK5 50-260 33 2.8e-33 102.13 In-house 1-218 (287) Show / Hide 
Range on Protein: 50-260
Range on HMM: 1-218/287
Sequence Identity: 33% (74 aa)

YEILDRIGSGKYSDVFTAY--KGKEIVAIKILKPTRD-----VKFLREAKILIDLRGGPNIVNLYDVVYTPLTNQYSFVFEYIPE--LKWQDLFASMTDY
|| ...|| | |  |. |   . .||||.|  .   .        .||  .|  |.  .||| |.||. .   .    |||.. .   |. | .    | 
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELK-HKNIVRLHDVIHS--EKKLTLVFEFCDQDLKKYMDSCNGEMDM

E-ARVYLYQLLRTLDYAHSHGIMHRDVKPLNILFDKKTYKLRLIDWGLA-DFYHPGQNYQIHVATRYYKPPELLLDYQKYDYSVDMWCFGVTMASLVFKI
. .. ..||||. | . |.| ..||| || | |  |.  .|.| | |||  |  | ..|   | |  | ||  |.  ..|  |.|||  |  .| ..   
HIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNG-ELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAG

YPFFRGSDDFDMISKISSVLGT
 | | |.|. |   .|  ..||
RPLFPGNDVEDQLKRIFKIMGT
Kinase 84774.m00068.AA CDC7 50-188 29 5.7e-27 76.41 In-house 1-156 (522) Show / Hide 
Range on Protein: 50-188
Range on HMM: 1-156/522
Sequence Identity: 29% (46 aa)

YEILDRIGSGKYSDVF--TAYKGK--------------EIVAIKILKPTRD-VKFLREAKILIDLRGGPNIVNLYDVVYTPLTNQYSFVFEYIPELKWQD
| ..|.||.| .| |.  |.....              ...|||.. ||      ..|   |  . | .|.. . . .      .  .| .| |  . ||
YKVHDKIGEGTFSSVYKATCQRQPHVNKFASHFWNYCRRKFAIKHHIPTSHPERIMNELQCLTRMGGHHNVMGMCCCFRY--NDHVHIVMPYFPHCSFQD

LFASMT--DYEARVYLYQLLRTLDYAHSHGIMHRDVKPLNILFDKKTYKLRLIDWGLA
....|.    |.. |.|.|.. | . |. || |||||| |.|.  .| | .|.| |||
FYFHMNRDMEEIKHYMYNLFYALRHVHQFGIIHRDVKPSNFLYNRRTKKFLLVDFGLA
Kinase 84774.m00068.AA RCK 143-260 33 3.6e-24 73.32 In-house 108-232 (298) Show / Hide 
Range on Protein: 143-260
Range on HMM: 108-232/298
Sequence Identity: 33% (43 aa)

RVYLYQLLRTLDYAHSHGIMHRDVKPLNILFDKK--------TYKLRLIDWGLA-DFYHPGQNYQIHVATRYYKPPELLLDYQKYDYSVDMWCFGVTMAS
. ..||.|  |.. |.||..|||.|| ||.  ..        .. . ..| ||.  ..   ..|   | ||.|  ||.||  ..|.. .|.| .|  |. 
KNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRS-KPPYTDYVSTRWYRAPECLLRCTYYNSPMDIWAVGCIMYE

LVFKIYPFFRGSDDFDMISKISSVLGT
|  .  | | ||.  | | || .|.||
LYML-RPLFPGSSEIDQIFKICKVMGT
Kinase 84774.m00068.AA CDC7 203-262 31 5.3e-13 33.73 In-house 331-390 (522) Show / Hide 
Range on Protein: 203-262
Range on HMM: 331-390/522
Sequence Identity: 31% (19 aa)

TRYYKPPELLLDYQKYDYSVDMWCFGVTMASLVFKIYPFFRGSDDFDMISKISSVLGTDG
|. . .||.|| . .  ...|.|  || . ||. . ||||. .||.. .  | . .|. .
TPGFRAPEVLLKCPDQTTAIDIWSCGVIFLSLLSGRYPFFMAPDDMTALAQIMTIFGSEE
Kinase 84774.m00068.AA CDK 287-331 31 4.6e-12 34.71 In-house 256-284 (284) Show / Hide 
Range on Protein: 287-331
Range on HMM: 256-284/284
Sequence Identity: 31% (14 aa)

PWWSFVNGENASLANEDAIDLLDKCIVYDHTERITAKEAMAHRYF
|..                |||.|. .|| . ||.|..|. | ||
PDY----------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 84774.m00068.AA CDC2 296-331 47 7.6e-12 32.15 In-house 266-301 (301) Show / Hide 
Range on Protein: 296-331
Range on HMM: 266-301/301
Sequence Identity: 47% (17 aa)

NASLANEDAIDLLDKCIVYDHTERITAKEAMAHRYF
| | .....||||.. ..||   ||.||||..|.||
NQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase 84774.m00068.AA RCK 300-331 40 6.3e-11 30.61 In-house 267-298 (298) Show / Hide 
Range on Protein: 300-331
Range on HMM: 267-298/298
Sequence Identity: 40% (13 aa)

ANEDAIDLLDKCIVYDHTERITAKEAMAHRYF
.. |.|.|. |.  .|  .||||..|  |.||
CSQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase 84774.m00068.AA RCK 50-124 39 2.4e-10 28.71 In-house 1-81 (298) Show / Hide 
Range on Protein: 50-124
Range on HMM: 1-81/298
Sequence Identity: 39% (32 aa)

YEILDRIGSGKYSDVFTAY--KGKEIVAIKILKPTR-----DVKFLREAKILIDLRGGPNIVNLYDVVYTPLTNQYSFVFEY
| |....| | |..|. |   . .|||||| .| ..     ... ||| | |  |   |||..|..|..   | | .|||||
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK-QKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEY
Kinase 84774.m00068.AA TyrKc 50-331 21 1.4e-09 -67.61 SMART 1-280 (280) Show / Hide 
Range on Protein: 50-331
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

YEILDRIGSGKYSDVFTAYKGKEIVAIKILKPTRDVKFLREAKILIDL-RGGPNIVNLYDVVYTPLT-----NQYSFVFEYIPE------LKWQDLFASM
 . .. .|.| .  |. .    . ||.| ||.     |.|||.|.  |    ||||.|| |. ..        ..  |.|| |       |.        
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--L

TDYEARVYLYQLLRTLDYAHSHGIMHRDVKPLNILFDKKTYKLRLIDWGLADFYHPG-------QNYQIHV--ATR-----YYKPPELLLDYQKYDYSVD
.  .   . .|  .  .| ||... |||    |.| ...    .  | ||. . . .       . |       ..        .|| . .| |.    |
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSD

MWCFGVTM---ASLVFKIYPFFRGSDDFDMISKISSVLGTDGLSEYLDKYGIPLPPNIHVYKSKRKPWWSFVNGENASLANEDAIDLLDKCIVYDHTERI
 | |||.|    ..  . ||        .|| .   ..  . . ||... . . .|  .       |  ||        . ..  ..  .|  .|  .| 
VWSFGVCMWEIFTYGQQPYP--------GMIQQ---MMSNQEVIEYVKQGYRMPQPPNDY------P-MSF------VCCPDEMYQIMKQCWHEDPEDRP

TAKEAMAHRYF
| .|   |..|
TFSEI--HECF
Kinase 84774.m00068.AA CDK5 301-331 41 1.4e-09 25.94 In-house 257-287 (287) Show / Hide 
Range on Protein: 301-331
Range on HMM: 257-287/287
Sequence Identity: 41% (13 aa)

NEDAIDLLDKCIVYDHTERITAKEAMAHRYF
.|   ||| | ....  .||.||.|. | ||
DEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase 84774.m00068.AA CAMK 302-331 23 3.5e-09 24.98 In-house 396-425 (425) Show / Hide 
Range on Protein: 302-331
Range on HMM: 396-425/425
Sequence Identity: 23% (7 aa)

EDAIDLLDKCIVYDHTERITAKEAMAHRYF
....||. |. ..| ..|.|......|  .
QECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 84774.m00068.AA CDC7 306-331 50 5e-06 12.42 In-house 497-522 (522) Show / Hide 
Range on Protein: 306-331
Range on HMM: 497-522/522
Sequence Identity: 50% (13 aa)

DLLDKCIVYDHTERITAKEAMAHRYF
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DLLDRCLEMNPHKRITAEEALKHPFF
Kinase 84774.m00068.AA Pkinase_Tyr 50-107 31 1.2e-05 19.81 Pfam 1-70 (270) Show / Hide 
Range on Protein: 50-107
Range on HMM: 1-70/270
Sequence Identity: 31% (22 aa)

YEILDRIGSGKYSDVFTAYKG------KEIVAIKILKPTRDVK------FLREAKILIDLRGGPNIVNLY
 ...  .|.| . .|. ..        |  ||.|.||.. . .      |.|||||.  |   ||||.||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLY