Gene 85876.m00184 (T.vaginalis)

85876.m00184

Species: T.vaginalis
Alias: TvagK0808, 85876.m00184
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: FRAY

Sequence

Name Sequence Type Origin Length Description Download
85876.m00184.AA Protein None 356 None Fasta, JSON
85876.m00184.kin_dom Protein Kinase Domain None 261 None Fasta, JSON

Protein domain

Protein domains of 85876.m00184.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85876.m00184.AA STE20 10-270 42 2.8e-116 392.6 In-house 1-288 (288) Show / Hide 
Range on Protein: 10-270
Range on HMM: 1-288/288
Sequence Identity: 42% (122 aa)

YEIKERIGRGGTSEVFSAVCLDNNEV----VSIKKIDLETGQ---IELDYLRQEVSYWSSMQHKNIISYYGSFIEG----PNIYILMSYCSAGSLYDILR
||. |.||.|.. .|. | . ...|.    | |||..||. .    |.. . .|.|  .  .|.||..||||.. .     ...|.| ||..||| ||..
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

IHMPNGLP------NEIQIATILKGTLNALDYIHSSGQIHRDVKPGNILIEGNGVVKIGDFGVSTRLFEEGQRRSFR---FTVAGTPCYMAPEVLIE---
 .|. | .      || |||.|....| .|||.|| ..||||.| .|||.  .| ||. ||||.  | ..| |....    |. |||..|||||. .   
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHG-RDTMQFKRNTFVGTPYWMAPEVIQCMEG

-EEGYTEKADIWSLGITAIELATGDAPYSTLNEMEIMMKII--NLPPPSLPS--NSKYSPEFIDFISKCLQTDPNNRWTAKELLSHPFI
 . ||..|.|||||||||||.|.|  ||. .. |  |..|.  . ||| | .   .|.|||| ||..|||| ||..|.||..||.||||
PDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase 85876.m00184.AA STE 10-270 31 5.3e-113 381.73 In-house 1-359 (359) Show / Hide 
Range on Protein: 10-270
Range on HMM: 1-359/359
Sequence Identity: 31% (114 aa)

YEIKERIGRGGTSEVFSAVCL------DNNEV---------VSIKKIDLETGQI----------------ELDYLRQEVSYWSSMQ--HKNIISYYGSFI
.|. |.||.|.. .|. |..       ...||         . ||...||. .                 |.. . .|..  . ..  |.||. |||...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EG-------PNIYILMSYCSAGSLYDILR-IHMPNGLPN----------EIQIATILKGTLNA-LDYIHSSGQIHRDVKPGNILIEGNGVVKIGDFGVST
 .        ...| | |...||| ||..  .....  |          | |||.|.. .| . |.|.|| . ||||.||.|||.     ||. ||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

RLFEEGQ-------------RRSFRFTVAGTPCYMAPEVLIE-----EEGYTEKADIWSLGITAIELATGDAPYSTLNEMEIMMKIINL-----------
.| ...              . . | |..||| .|||||.       . ||..|.||||||.|.||.|||  |..... |. |. |..            
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----PPPSLPS-----------------NSKYSPEFIDFISKCLQTDPNNRWTAKELLS--HPFI
    |||.||.                  .|.||||.|||.|||| |||.|.||..||.  ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 85876.m00184.AA FRAY 10-270 44 3.7e-109 340.25 In-house 1-277 (277) Show / Hide 
Range on Protein: 10-270
Range on HMM: 1-277/277
Sequence Identity: 44% (123 aa)

YEIKERIGRGGTSEVFSAVCLDNNEVVSIKKIDLETGQ-IELDYLRQEVSYWSSMQHKNIISYYGSFIEGPNIYILMSYCSAGSLYDILRIHMPNGLP--
|| .| || |.|  |. |.|.  .| . || |.||  |   .| |. |.   .. .| |...|. ||..   . . | | ..||. ||..  || | |  
YELQEVIGEGATAVVHKAYCIPRQENCAIKRINLEKCQNTSMDELIKEIQAMCQCHHPNVVHYHTSFVVNEELWLVMRYLECGSCLDIMKFKMPQGEPHK

----NEIQIATILKGTLNALDYIHSSGQIHRDVKPGNILIEGNGVVKIGDFGVSTRLFE--EGQRRSFRFTVAGTPCYMAPEVLIEEEGYTEKADIWSLG
     |  |||||| .| .|.| |. ||||||.| |||||  .| . | |||||  | .  .  |   | |  |||| |||||. . .||  ||||||.|
QGVFDEHVIATILKEVLKGLCYFHKNGQIHRDIKAGNILIGEDGTIQIADFGVSAWLATGGDLSRCCVRHTFVGTPCWMAPEVMEQVHGYDFKADIWSFG

ITAIELATGDAPYSTLNEMEIMMKIINLPPPSLPSN--SK-----YSPEFIDFISKCLQTDPNNRWTAKELLSHPFI
||||||||| |||  .  | ..| .   .||||  .  .|     |.. | . |.|||| || .| || ||| | | 
ITAIELATGKAPYHKYPPMKVLMLTLQNDPPSLETDEDDKDMYKKYGHSFKKMIEKCLQKDPSKRPTASELLKHKFF
Kinase 85876.m00184.AA YSK 10-270 40 2.8e-105 318.0 In-house 1-257 (257) Show / Hide 
Range on Protein: 10-270
Range on HMM: 1-257/257
Sequence Identity: 40% (107 aa)

YEIKERIGRGGTSEVFSAVCLDNNEVVSIKKIDLETGQIELDYLRQEVSYWSSMQHKNIISYYGSFIEGPNIYILMSYCSAGSLYDILRIHMPNGLPNEI
. . |.||||   ||. ..    ..|| || ||||    | . . ||.   |.    .|  ||||. ..  . | | ||  ||. | ..    .... |.
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFD-EK

QIATILKGTLNALDYIHSSGQIHRDVKPGNILIEGNGVVKIGDFGVSTRLFEEGQRRSFRFTVAGTPCYMAPEVLIEE-EGYTEKADIWSLGITAIELAT
.||.||.  | .|||.||   ||||.|  |.|.  .| ||..||||. .. .  ..|    | .||| .|||||  .|  .| .|||||||||||.|.|.
YIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRN---TFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAK

GDAPYSTLNEMEIMMKIINLPPPSLPSNSKYSPEFIDFISKCLQTDPNNRWTAKELLSHPFI
|  ||. .  |  |  |.  .||.| . ..||  |..|.  ||  ||..| .|||||.| ||
GEPPYCDYHPMRVMFLIPKNNPPKL-EGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase 85876.m00184.AA MST 10-270 43 1.5e-93 297.69 In-house 1-254 (254) Show / Hide 
Range on Protein: 10-270
Range on HMM: 1-254/254
Sequence Identity: 43% (114 aa)

YEIKERIGRGGTSEVFSAVCLDNNEVVSIKKIDLETGQIELDYLRQEVSYWSSMQHKNIISYYGSFI--EGPNIYILMSYCSAGSLYDILRIHMPNGLPN
..| |..|.|    |. |... ....| ||..  ..    |. .  | |  . .. |.|  ||||..      . | | || .||. || .|   .   |
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNE---DLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKIT--QRTLN

EIQIATILKGTLNALDYIHSSGQIHRDVKPGNILIEGNGVVKIGDFGVSTRLFEEGQRRSFRFTVAGTPCYMAPEVLIEEEGYTEKADIWSLGITAIELA
| |||.||..||  |.| |..  |||| |.||||.   |  |  |||||  |..   .   | || |||..||||| |.| .|. |||||||||||||.|
EQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTD---TMAKRNTVIGTPYWMAPEV-IQEIKYDCKADIWSLGITAIEMA

TGDAPYSTLNEMEIMMKIINLPPPSLPSNSKYSPEFIDFISKCLQTDPNNRWTAKELLSHPFI
 |  ||| .  |  | .|.  |||..   ...|.||.||..|||| .|. ||||..||.||||
EGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase 85876.m00184.AA S_TKc 10-270 33 7e-92 312.46 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-270
Range on HMM: 1-231/231
Sequence Identity: 33% (93 aa)

YEIKERIGRGGTSEVFSAVCLDNNEVVSIKKIDLETGQIELDYLRQEVSYWSSMQHKNIISYYGSFIEGPNIYILMSYCSA--GSLYDILRIHMPNGLP-
||| . ||.|. ..|. ..  . ...| ||.|.        . .|.|..  .. .|.||. .|..| .  ..|. | ||.   |.|.|... . ..||. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

--NEIQIATILKGTLNALDYIHSSGQIHRDVKPGNILIEGNGVVKIGDFGVSTRLFEEGQRRSFRFTVAGTPCYMAPEVLIEEEGYTE-KADIWSLGITA
  .| ... ... ...||.|.|| | ||||.|| |||.    ..||.|||....|           |. ||| |||||||    ||.  |.|.||.|.. 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL

IELATGDAPYSTLNEMEIMMKIINLPPPSLPSNSKYSPEFIDFISKCLQTDPNNRWTAKELLS-------HPFI
.|...|  |..   .|. |.|.|             |||..|||.|||| ||..|.|| |.|        ||..
YEMLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 85876.m00184.AA Pkinase 10-270 29 9.4e-81 279.38 Pfam 1-293 (293) Show / Hide 
Range on Protein: 10-270
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

YEIKERIGRGGTSEVFSAVCLDNNEVVSIKKIDLETGQIELDYLRQ---EVSYWSSMQHKNIISYYGSFIEGPNIYILMSYCSAG----SLYDILRIHMP
|.|...||.|. ..|. ..  .....| .|.|....   . |. .    |...  ...|.||. .|..| ....||. | ||  |    .|.|...  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-WR

NGLP--NEIQIATILKGTLNALDYIHSSGQIHRDVKPGNILIEGNGVV----KIGDFGVSTRLFEEGQRRSFRFTVAGTPCYMAPEVLIEEEGYTEKADI
.|     | ..  ... .| .|.|.|| | ||||.|| ||||  ||..    ||.|||..  .     . |   |..||| ||||||. . ..|. |.|.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGITAIELATGDAPYSTL------NEMEIMMKIIN--LPPPSLPSNSKY----------------SPEFIDFISKCLQTDPNNRWTAKELLSHPFI
||.|.. .|...|  |..        ..|... .|    |. ..  ..|..                |.|..|||..||. ||. |.||...| ||..
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 85876.m00184.AA PAKL 67-270 44 9e-74 251.4 In-house 57-256 (256) Show / Hide 
Range on Protein: 67-270
Range on HMM: 57-256/256
Sequence Identity: 44% (92 aa)

NIISYYGSFIEG-PNIYILMSYCSAGSLYDILRIHMPNGLPNEIQIATILKGTLNALDYIHSSGQIHRDVKPGNILIEGNGVVKIGDFGVSTRLFEEGQR
||.||.||   .  .. ||| |||.||  |.. .     | || ||. ||. ||. | | ||.. ||||.|  |||.   . ||| ||||| .|      
NIVSYFGSIQQKLNHYWILMDYCSLGSINDMMES-CCKTL-NEKQISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQL-----Q

RSFR---FTVAGTPCYMAPEVLIEEEGYTEKADIWSLGITAIELATGDAPYSTLNEMEIMMKIINLPPPSLPSNSKYSPEFIDFISKCLQTDPNNRWTAK
 ...      .||| .||||. |    |  |.|||||||||||.| |  | .... |  |. | | ||| .    ..||.| ||. .|.. ||. || . 
DEYDGQANQMIGTPYWMAPEI-INKQNYNNKCDIWSLGITAIEMADGFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPI

ELLSHPFI
.||.||||
DLLCHPFI
Kinase 85876.m00184.AA PAKA 10-270 37 2.2e-70 240.14 In-house 1-260 (260) Show / Hide 
Range on Protein: 10-270
Range on HMM: 1-260/260
Sequence Identity: 37% (100 aa)

YEIKERIGRGGTSEVFSAVCLDNNEV--VSIKKIDLETGQIELDYLRQEVSYWSSMQHKNIISYYGSFIEGPNIYILMSYCSAGSLYDILRIHMPNGLP-
|.  | || |.. ||. |  . .|.   | ||...... |   . .  | .   . .||||. |. |..    ... | | ..|.| |..       .  
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKN-QPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNY

-NEIQIATILKGTLNALDYIHSSGQIHRDVKPGNILIEGNGVVKIGDFGVSTRLFEEGQRRSFRFTVAGTPCYMAPEVLIEEEGYTEKADIWSLGITAIE
 .| ||| ... .| .|..||| ..||||.|  |||.  .| ||| |||  ..| .| |.|.   |. ||| .||||| |    | || ||||||| |||
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRN---TMVGTPYWMAPEV-IRRKQYDEKVDIWSLGIMAIE

LATGDAPYSTLNEMEIMMKIINLPPPSLPSNSKYSPEFIDFISKCLQTDPNNRWTAKELLSHPFI
.. |  ||   .    |  | .   | . .  | |.|| || .|||. |. .|..|.|||.|||.
MIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase 85876.m00184.AA STE11 10-270 33 2.9e-66 226.44 In-house 1-303 (303) Show / Hide 
Range on Protein: 10-270
Range on HMM: 1-303/303
Sequence Identity: 33% (103 aa)

YEIKERIGRGGTSEVFSAVCLDNNEVVSIKKIDLETGQI-------ELDY------LRQEVSYWSSMQHKNIISYYGSFI---EGPNIYILMSYCSAGSL
.  .| ||.|  . |.... .|..|.. .|.| ..           |..       ...|..  . ..||||. |||. .   .  ...| | ||. |||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

YDILRIH-----MPNGLPNEIQIATILKGTLNALDYIHSSGQIHRDVKPGNILIEGNGV-VKIGDFGVSTRLFEEGQR-----------RSFRFTVA---
 ..||       .     .|  |    |  | .| | || | ||||.|. |||.  .|. .|..||| ..|| .....           .|.. |.    
SSMLRHKWGPMKF-----DEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSM

-GTPCYMAPEVLIEEE--GYTEKADIWSLGITAIELATGDAPYSTL--NEMEIMMKIINL--PPPSLPSNSK----YSPEFIDFISKCLQTDPNNRWTAK
 ||| .|||||. .|   ||. |||||||| | || |||  |.. .  |.| .|.||.    |.| .|..       |.|  ||...|.. ||. |.|| 
MGTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTAN

ELLSHPFI
.|| ||||
QLLQHPFI
Kinase 85876.m00184.AA KHS 10-270 38 1e-65 219.98 In-house 1-258 (258) Show / Hide 
Range on Protein: 10-270
Range on HMM: 1-258/258
Sequence Identity: 38% (103 aa)

YEIKERIGRGGTSEVFSAVCLDNNEVVSIKKIDLETGQIELDYLRQEVSYWSSMQHKNIISYYGSFIEGPNIYILMSYCSAGSLYDILRIHMPNGLPNEI
||.  |.| |   .|. |     .|.. .| | .| |. ..  . ||.      .| ||..|.||..    ..| | || .||| || ..    |  .|.
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGD-DFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHV---TGPLSEL

QIATILKGTLNALDYIHSSGQIHRDVKPGNILIEGNGVVKIGDFGVSTRLFEE-GQRRSFRFTVAGTPCYMAPEVLIEEE--GYTEKADIWSLGITAIEL
||| . . ||..|.|.|| |..|||.|  |||.  .| ||. |||||...    ..|.||     ||| .|||||   |   || .  |||..|||||||
QIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSF----IGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIEL

ATGDAPYSTLNEMEI--MMKIINLPPPSLPSNSKYSPEFIDFISKCLQTDPNNRWTAKELLSHPFI
|    |   |  | .  .|   |  || |   .|.|. | .|.  .|  .|  | ||. ||.|||.
AELQPPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase 85876.m00184.AA Ciliate-E2 10-270 23 3.3e-64 219.31 In-house 1-365 (365) Show / Hide 
Range on Protein: 10-270
Range on HMM: 1-365/365
Sequence Identity: 23% (91 aa)

YEIKERIGRGGTSEVFSAVCLDNNEVVSIKKIDLET--------------------GQIELDYLRQEVSYW----------------SSMQHKNIISYYG
|.. . ||.|. . |. .    ... . ||.||                        . .. .. || . .                ....|.||| .| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

SFI--EGPNIYILMSYCSAGSLYDILRIH---MPNGLP-----NEIQIATILKGTLN---------------ALDYIHSSG-QIHRDVKPGNILIEGNGV
.|.     |||. | ||. |.|.|.....    .. ..     .| .|..| |  |.               || |.|| .  |||| || |||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKIGDFGVST----------------RLFEEGQRRSFRFT-------------VAGTPCYMAPEVLI--------EEEGYTEKADIWSLGITAIELATGD
.|| ||| |.                 . . ....|  ..             ..||| |||||.|         ...||..|.||||||..  |. .| 
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

APYSTLNEMEIMMKIINLPPPSLP----------------SNSKYSPEFIDFISK----CLQTDPNNRWT-AKELLSHPFI
 |.         ...|   . ..|                |. | |.| .|.|.|    .|| ||..| | ....| ||..
PPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 85876.m00184.AA Pkinase_Tyr 10-222 25 5.4e-20 68.35 Pfam 1-225 (270) Show / Hide 
Range on Protein: 10-222
Range on HMM: 1-225/270
Sequence Identity: 25% (57 aa)

YEIKERIGRGGTSEVFSAVCL----DNNEVVSIKKIDLETGQIE--LDYLRQEVSYWSSM-QHKNIISYYGSFI-EGPN--IYILMSYCSAGSLYDILRI
 .. . .|.|   ||. ...     ...  | .|..   . . .  .. . .|..  ... .|.||...||  . .|    ||| | |.  |.|.| || 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

H-MPNGLPNEIQIATILKGTLNALDYIHSSGQIHRDVKPGNILIEGNGVVKIGDFGVSTRLFEEGQR-RSFRFTVAGTPCYMAPEVLIEEEGYTEKADIW
| .... ..  ..  .     ....| .| . ||||.   |.|.. |.||||.||| .  ......  |.   .       ||||.. . . .|.| |.|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGK-FTTKSDVW

SLGITAIELAT-GDAP-YSTLNEMEIM
| |..  |. | |. | |  .   |..
SFGVLMWEIFTYGEQPTYPGMSNEEVY
Kinase 85876.m00184.AA TyrKc 10-270 22 5.5e-16 35.78 SMART 1-280 (280) Show / Hide 
Range on Protein: 10-270
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

YEIKERIGRGGTSEVFSAVCLDNNEVVSIKKIDLETGQIELDYLRQEVSYWSSM--QHKNIISYYGSFIEG-------PNIYILMSYCSAGSLYDILRIH
 . .. .|.|   ||. ..     . | .|..  ..    .  ...| .  ..   .|.||.  ||  ...       . ..|.| |.. |.| | || |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

MPNGLPNEIQIATILKGTLNALDYIHSSGQIHRDVKPGNILIEGNGVVKIGDFGVSTRLFEE--------GQRR----SFR--FTVAGTPCYMAPEVLIE
 |.   .  .   .     .  .|.|| . ||||    |.|.  |..|||.||| |  . ..          |     . .  . .      ||||..  
RPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR----WMAPECI--

EEG-YTEKADIWSLGITAIELAT-GDAPYST-----LNEMEIMMKIINLPPPSLPSN------SKYSPEFIDFISKCLQTDPNNRWTAKELLSHPFI
 .| .|.| |.|| |..  |. | |. ||.      ..  |.. .. .   .  | |         ..|  . ...| . ||..| | .|.  | ..
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF