Gene 83007.m00270 (T.vaginalis)

83007.m00270

Species: T.vaginalis
Alias: 83007.m00270, TvagK0771
External Links:
Annotation:

Classification

Group: Other
Family: PLK
Subfamily: PLK1

Sequence

Name Sequence Type Origin Length Description Download
83007.m00270.AA Protein None 476 None Fasta, JSON
83007.m00270.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of 83007.m00270.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 83007.m00270.AA S_TKc 23-277 32 7.4e-89 302.43 SMART 1-231 (231) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-231/231
Sequence Identity: 32% (89 aa)

YDFVSELGEGGFASVFHVRRESDHKSFALKVIPHEALQNENFKAKHFAEIEIQSKMDHKNIVKSYDHFKDENNTYILMELCLK--GNVKNYLSRKGA---
|... ..|.|.|..|. .|  .... .|.|.|.           .   ||.| .| .|.|||| ||.| | .. |. ||.|    |... |. ..|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LSEKEAAKIIKSVCSGVKYCHDHHIIHRDLKLDNFMISDDGDIKIIDFGVSEIVSDSKKKDFVFAGTPMYMGPEVIGLHQYGY-QVDIWAIGICTFE
   ..| .|..... .|....|||.|.||||||| .| ....   |||.|||.. ..         | ||| || |||.   .||.  .|.|..|.. .|
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LLTGHPPFEANNMKDMSKLIVSGEFRFPPNIQLSFVAKDFIESALQVKPSLRPNIRELLK-------HPFL
.|.| |||.  .|. | |.|.            |  |||||.  ||. |. || . |.|.       ||..
MLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 83007.m00270.AA AGC 23-277 20 2.2e-88 227.91 In-house 1-395 (395) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-395/395
Sequence Identity: 20% (82 aa)

YDFVSELGEGGFASVFHVRRESDH------KSFALKVIPHEA---LQNENFKAKHFAE------------IEIQSKMD----------HKNIVK-SYDHF
..|.  .|.|.|  |. ||. ...      | .|.||.  .    . ..|  ..  .|             .| .|..          | .|||  .  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

KDENN--TYILMELCL---------KG-NVKNYLS---RKGALSEKEAAKIIKS-------VCSGVKYCHD-HHIIHRD-LKLDNFMISDDGDIKIIDFG
.|...   |..||..           |     .|    ..| ..|..|  ..         ..... | |. ..||||| ||..| .. .|| ||. |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

VSEIVSDSK--------------------------------------------------KKDFVFAG--TPMYMGPEVIGLHQYGYQVDIWA--IGICTF
 . .. ...                                                  ..   | |  || || ||..    ||...|.|.   |.. .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELLTGHPPFEANNMK----------DMSKLIV------SGEFRFPPN--------IQLSFVAKDFIESALQVKPSLRPN----------IRELLKHPFL
|.|||.||| ..|            .| ..|       . . .||..         ..|  |||.|.  |.. |. |.           . |. .||. 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 83007.m00270.AA CAMK 28-277 22 1.6e-86 278.69 In-house 1-425 (425) Show / Hide 
Range on Protein: 28-277
Range on HMM: 1-425/425
Sequence Identity: 22% (95 aa)

ELGEGGFASVFHVRRESDH------------KSFALKVIPHEALQ------------NENFKAKH-------------FAEIEIQSK-------MDHKNI
.||.|.|. |. ... ..             . .| |.|. . |.             .. |.||             . |||| .|       .||.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKSYDHFKD-------------------ENNTYILM---ELCLKG----NVKNYLSRK---------------GALSEKEAAKIIKSVCSGVKYCHDHHI
.| |... |                   ... |. |   |.|  |     . .|. ..               | ..|.||..... .||.|.|||.|.|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKLDNFMISDD-----------------GDIKIIDFGVSEIVSDSK-----------------------KKDFVFAGTPMYMG-PEVIG-------
.|||||..| ...|.                 ..||||||| . .. ...                       .|   | ||| ||  |||.        
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------LHQYGYQVDIWAIGICTFELLTGHPPFEAN-------------NMKDMSKLIVSGEFRFPPNI----------------------QLSFVAKD
          ||...|.|..|. .. .|.|.|||..              |.... . | .|...|||                        ..|  .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FIESALQVKPSLRPNIRELLKHPFL
.| . ||| |. |..| . |.||..
LIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase 83007.m00270.AA Pkinase 23-277 30 1.1e-82 285.76 Pfam 1-293 (293) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

YDFVSELGEGGFASVFHVRRESDHKSFALKVIPHEALQNENFKAKHFA--EIEIQSKMDHKNIVKSYDHFKDENNTYILMELCLKG----NVKNYLS--R
| ... .|.|.|..|.. .. .. | .|.|.|. .  ......  |.   ||.|  ...|.|||. || | |... |. ||.| .|      . |.|  |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

KGAL--SEKEAAKIIKSVCSGVKYCHDHHIIHRDLKLDNFMISDDGDI----KIIDFGVSE---IVSDSKKKDFVFAGTPMYMGPEVIG-LHQYGYQVDI
.|..  ||.|. .... ...|..|||.. |||||||..|..|...|.|    ||.|||...   . ..|  ..|.  ||| || ||||     ||. ||.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFC--GTPWYMAPEVIRGGQYYGPKVDM

WAIGICTFELLTGHPPFEAN------NMKDMSKLIVSGEFRFPPNIQLS-------------------FVAKDFIESALQVKPSLRPNIRELLKHPFL
|..|.  .|.|.|.|||         ... | ..| .....|.     |                     .||||.. |...|. ||.....|.||..
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 83007.m00270.AA PLK 23-277 36 3.7e-82 267.35 In-house 1-258 (258) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-258/258
Sequence Identity: 36% (93 aa)

YDFVSELGEGGFASVFHVRRESDHKSFALKVIPHEALQNENFKAKHFAEIEIQSKMDHKNIVKSYDHFKDENNTYILMELCLKGNVKNYLSRK-GALSEK
|   . ||.|||| .. ..  . .. .| ||.|.. .| .... |   ||||.. ..|.|||| ...| |..| ||..|.| ..    |. |.  .|.| 
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

EAAKIIKSVCSGVKYCHDHHIIHRDLKLDNFMISDDGDIKIIDFGVSEIVSDSKKKDFVFAGTPMYMGPEVI-GLH-QYGYQVDIWAIGICTFELLTGHP
|.  ..  ...|.|| |.| |||||||| |. ..|.  .|| ||| .  .     .   . ||| |  |||  | .  ..|.||.|..|.    ||.|.|
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFEANNMKDMSKLIVSGEFRFPPNIQLSFVAKDFIESALQVKPSLRPNIRELLKHPFL
|||... |.. | |.  ...|| ....| .|||.| . |.  |. ||.| ..| |||.
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase 83007.m00270.AA CAMKL 23-277 27 8e-80 254.39 In-house 1-297 (297) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-297/297
Sequence Identity: 27% (82 aa)

YDFVSELGEGGFASVFHVRRESD-HKSFALKVIPHEALQNENFKAKHFA------------EIEIQSKMD---HKNIVKSYDHFKDENN------TYILM
|... .||.|.|. |   . ..   .  | |.|  . ..|. .. |..             ||.|.....   |.||.| |... ....       |. |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCLKGN--VKNYLSRKGA----LSEKEAAKIIKSVCSGVKYCHDHHIIHRDLKLDNFMISDDGD--IKIIDFGVSEIVSD----SKKKDFVFAGTPMYM
|.|  |.    .|. ..|     ..|.|| .. . ..|.|.|||.|.|.|||.|..| .....|.  ||||||| | .  .    . .|   | |.| ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

GPEVIGL---HQYGYQVDIWAIGICTFELLTGHPPFEANNMK-------DMSKLIVSGEFRFPPNIQLSFVAKDFIESALQVKPSLRPNIRELLKHPFL
 ||..     . .|..||||..|.  . ...|. ||.. ...        . . | .| ...|. ...|  ..|.| . |||.|. ||.| ....||..
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 83007.m00270.AA PLK-Unclassified 23-277 35 1.2e-77 264.24 In-house 1-264 (264) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-264/264
Sequence Identity: 35% (94 aa)

YDFVSELGEGGFASVFHVRRESDHKSFALKVIPHEALQNENFKAKHFAEIEIQSKMDHKNIVKSYDHFKDENNTYILMELCLKGNVKNYLSRK-------
|   . ||.|||| .. |   .  | .| |.||   |. . .. |   ||.|.. ..|||||| .. | |. | |||.|.|  | .  |. |.       
YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK

GALSEKEAAKIIKSVCSGVKYCHDHHIIHRDLKLDNFMISDDGDIKIIDFGVSEIVSD-SKKKDFVFAGTPMYMGPEVIGLHQ--YGYQVDIWAIGICTF
  |.| |.  .   .. ..|| |.. |||||||| |  ..|.  .|| ||| .  .   . ||.  . ||| |  ||.    .  ..|.||.|..|.   
KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKK-TICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILY

ELLTGHPPFEANNMKDMSKLIVSGEFRFPPNIQLSFVAKDFIESALQVKPSLRPNIRELLKHPFL
 ||.|.||||..  |   | | . .. || ....|  |||.| . |.  |. ||.| ....|||.
TLLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY
Kinase 83007.m00270.AA Ciliate-E2 23-277 22 1.9e-75 256.97 In-house 1-365 (365) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-365/365
Sequence Identity: 22% (86 aa)

YDFVSELGEGGFASVFHVRR-----------------------ESDHKSFALKVIPHEALQNENFKAKHFAEIE----------IQSKMDHKNIVKSYDH
|.|.  .|.|.|.||. ...                       . . | .|.|.. .  ... . . . . ||.          |.....|.||.| |..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FK--DENNTYILMELCLKGNVKNYLS------------RKGALSEKEAAKIIKSVCS---------------GVKYCHDHH-IIHRDLKLDNFMISDDGD
|.  |.|| |. ||.|  |. . |.               . ..|||...|.| ...               ...|.|  . |||||.|..| ..     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKIIDFGVSEIVSDS----------KKKDFVF----------------------AGTPMYMGPEVIGLHQ---------YGYQVDIWAIGICTFELLTGH
||||||| | ...|.          |.. | .                      .|||.|| ||...  .         |.|..|||..|.. .|.|.| 
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

PPFEANNMKDMSKLIVSGEFRFPPN----------------IQLSFVAKDFIES----ALQVKPSLRPN-IRELLKHPFL
|||         . |  ....||..                 ..|  .||.|       ||..|. |.. . ..|.||..
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 83007.m00270.AA Ciliate-E2-Unclassified 23-277 23 8e-73 248.24 In-house 1-352 (352) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-352/352
Sequence Identity: 23% (82 aa)

YDFVSELGEGGFASVFHVRRESDHKSFALKVIP-----HEALQNENFKAKHFAEIEIQSK------------------MDHKNIVKSYDHFKDENNTYIL
| ..  .|.|||..|........ . .|.| .      .  .....   . . ..|...|                  ..| .||| ...|.|..| || 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MELCLKGNVKNYLSRKGA-----------------LSEKEAA-----KIIKSVCSGVKYCHDHH-IIHRDLKLDNFMISDDG---DIKIIDFGVSEIVSD
||.|  |. ..|.. ..                  ..|..|.     .... ...| .|.|  . |||||.|..| .....|    ||||||| |    .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

S---------------KKKDFVFAGTPMYM----GPEVIGLHQYG----YQVDIWAIGICTFELLTGHPPFEANNMKD----------------MSKLIV
.               ...   |.|||.||     |||.. ..|.    |..|||. |.. .|.|.| .||..|| ..                . . | 
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

SGEFRFPPNI------QLSFVAKDFIE----SALQVKPSLRPNIRELLKHPFL
 ... ||.        ..|. |||||.    . |...|. |... ..|.||..
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 83007.m00270.AA STE 23-277 23 1.4e-72 247.42 In-house 1-359 (359) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-359/359
Sequence Identity: 23% (86 aa)

YDFVSELGEGGFASVFHVRRES---------------DHKSFALKVIPHEALQN--------------ENFKAKHFAEIEIQSKMD--HKNIVKSYDHFK
.......|.|.| .|.  ..                  .. .| |....|  .|              .. . .   ||.| .|..  |.|||| |... 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DE-------NNTYILMELCLKGNVKNYLSRK--------------GALSEKEAAKIIKSVCSG-VKYCHDHHIIHRDLKLDNFMISDDGDIKIIDFGVSE
.|       .. .| ||..  | .   . .|              . ..|.. |.|..... |  .| |.|||||||.| .| ..     .|..||||. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

IVSDS----------------KKKDFVFAGTPMYMGPEVIGL------HQYGYQVDIWAIGICTFELLTGHPPFEA-NNMKDMSKLIVS-GEFR------
...||                ..|   |.||| .| ||||        ..|....||| .|..  |..||.||.   ..|. |   . . . ..      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----FPPNIQ---------------------LSFVAKDFIESALQVKPSLRPNIRELLK--HPFL
     || ..                     .|   ||||.  ||  |. ||.  .|||  |||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 83007.m00270.AA MARK 23-277 32 3.4e-72 235.32 In-house 1-262 (262) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-262/262
Sequence Identity: 32% (87 aa)

YDFVSELGEGGFASVFHVRRESDHKSFALKVIPHEALQNENFKAKHFAEIEIQSKMDHKNIVKSYDHFK--DENN-TYILMELCLKGNVKNYLSRK--GA
| .. ..|.|..| |  ..    .. .|.|... . |.  . . . . |||| .|.||.||.| .. .   .|.. .|. ||.. .|.. .|.  .  | 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSEKEAAKIIKSVCSGVKYCHDHHIIHRDLKLDNFMISDDG--DIKIIDFGVSEIVSDSKKKDFVFAGTPMYMGPEVIGLHQYG-YQVDIWAIGICTFEL
|.|.|| .| . ..|.|.|||...|.|||.|..| .| ..|  .||||||| | |   . .|   | ||| || ||..    |  . ||||. |.  . .
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFS-ICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

LTGHPPFEANN--MKDMSKLIVSGEFRFPPNIQLSFVAKDFIESALQVKPSLRPNIRELLKHPFL
..|. ||.. .  .|.. | |..|....|..  .|  ....| . |.| |. || | |..|||..
VCGYFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 83007.m00270.AA PLK1 23-277 34 5e-68 222.61 In-house 1-253 (253) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-253/253
Sequence Identity: 34% (88 aa)

YDFVSELGEGGFASVFHVRRESDHKSFALKVIPHEALQNENFKAKHFAEIEIQSKMDHKNIVKSYDHFKDENNTYILMELCLKGNVKNYLSRKGALSEKE
|.    ||.||||  . .| .. .. || ||.| . |  .. . |   ||.|  ...|..||| ...| |..| ||..||| .  .     |..|. | |
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE

AAKIIKSVCSGVKYCHDHHIIHRDLKLDNFMISDDGDIKIIDFGVSEIVSDSKKKDFVFAGTPMYMGPEVIGLHQYGYQVDIWAIGICTFELLTGHPPFE
.   .. .  |..| |. .|||||||| |  . |. ..|| |||.   .  .  .    .||| |. |||.  .   . ||||.||   . || |.||||
CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLNKKGHSFEVDIWSIGCIMYILLFGQPPFE

ANNMKDMSKLIVSGEFRFPPNIQLSFVAKDFIESALQVKPSLRPNIRELLKHPFL
.. .|.  . |   |.| | .|  | .|...|.. |. .|. ||.|...|.  |.
TKCLKETYSRIKKNEYRIPSHI--SQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase 83007.m00270.AA TyrKc 23-277 21 8.6e-17 48.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 23-277
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

YDFVSELGEGGFASVFHVRRESDHKSFALKVIPHEALQNENFKAKHFAEIEIQSKM--DHKNIVKSYDHFKDE-------NNTYILMELCLKGNVKNYLS
  .  .|||| |  |.. .        | |.. ..|      ..    |..| .|   .|.|||. |    ..          .|.||.. .|. |.|| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RKGA-LSEKEAAKIIKSVCSGVKYCHDHHIIHRDLKLDNFMISDDGDIKIIDFGVSEIVSDS-----KKKDFVFA---GTPM-----YMGPEVIGLHQYG
...  |. |.  ..   ...|  | |....|||||   | ...... .|| ||| |  . |       |.  . .   |. .      | ||.|  . . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

YQVDIWAIGICTFELLT-GHPPFEA-----NNMKDMSKLIVSGEFRFPPNI--------QLSFVAKDFIESALQVKPSLRPNIRELLKHPFL
 . |.|. |.| .|..| | .| .       . ... ... .|. . .|            . . .  ...  . .|. ||. .|.  | ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF
Kinase 83007.m00270.AA Pkinase_Tyr 23-168 25 4.6e-12 41.48 Pfam 1-158 (270) Show / Hide 
Range on Protein: 23-168
Range on HMM: 1-158/270
Sequence Identity: 25% (41 aa)

YDFVSELGEGGFASVFHVRRE----SDHKSFALKVIPHEALQNENFKAKHFAEIEIQSKM-DHKNIVKSYDHFK-DENN--TYILMELCLKGNVKNYLSR
  |  .|||| | .|.. .      ...   | |.... | . .|.... ..|..| ... .|.|||. |     ..     || ||.. .|. ..|| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----KGALSEKEAAKIIKSVCSGVKYCHDHHIIHRDLKLDNFMISDDGDIKIIDFGVS
    |..|. |.  ..   ...|  | .....|||||   | ...... .|| ||| .
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 83007.m00270.AA Pkinase_Tyr 190-237 23 2.934946 1.5 Pfam 183-233 (270) Show / Hide 
Range on Protein: 190-237
Range on HMM: 183-233/270
Sequence Identity: 23% (12 aa)

PEVIGLHQYGYQVDIWAIGICTFELLT-GHPP-FEANNMKDMSKLI-VSGE
||.|    .  . |.|. |.. .|..| |  | ..     .. ..|  .|.
PECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGY