Gene 86485.m00568 (T.vaginalis)

86485.m00568

Species: T.vaginalis
Alias: TvagK0945, 86485.m00568
External Links:
Annotation:

Classification

Group: Other
Family: Other-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
86485.m00568.AA Protein None 601 None Fasta, JSON
86485.m00568.kin_dom Protein Kinase Domain None 111 None Fasta, JSON

Protein domain

Protein domains of 86485.m00568.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 86485.m00568.AA Ciliate-E2-Unclassified 176-291 23 1.6e-21 71.43 In-house 102-265 (352) Show / Hide 
Range on Protein: 176-291
Range on HMM: 102-265/352
Sequence Identity: 23% (39 aa)

YCQNGTLTSYVTNNPD-----------------LTNSQLI-----QIFINTCNLVMKIHSRK-ILIRDIKPDNILIDDNL---IPHISDFDVA-------
||..|.|  | ....                  .|  | .     ..|   ..   ..|. . |. |||||.|||.|.|     . |.||  .       
YCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNN

-----------LIDQMESTEYVGTELFM----APEVKKNKEGICPYG----VKSEIYSLGCVLSWMFT
            ..|....  .||  .|    |||| ....    |.     |. |.|||..| .| .
NCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQN----YDHSKAYKCDIWSLGVILYEMLF
Kinase 86485.m00568.AA Ciliate-E2 176-291 21 1.5e-18 60.3 In-house 115-291 (365) Show / Hide 
Range on Protein: 176-291
Range on HMM: 115-291/365
Sequence Identity: 21% (40 aa)

YCQNGTLTSYVTNNPD-----------LTNSQLIQIFINTCN--------------LVMK-IHSRK-ILIRDIKPDNILIDDNLIPHISDFDVALIDQME
||| |.| .|  ||.            .|  . ..|.   ..              | .. .||.. |. |||||.|||.     . |.||  . . . .
YCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDD

STE----------------------------------YVGTELFMAPEVKKNKE-----GICPYGVKSEIYSLGCVLSWMFT
. .                                  ..||  .||||. ..|.     .  .|. |. |.|||..| .| .
NQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF
Kinase 86485.m00568.AA TKL 176-333 19 2.1e-18 62.92 In-house 119-364 (364) Show / Hide 
Range on Protein: 176-333
Range on HMM: 119-364/364
Sequence Identity: 19% (50 aa)

YCQNGTLTSYVTNNPDLTNSQLIQIFINTCNLVMKIHSRK--------ILIRDIKPDNILIDDNLI--------------PHISDFDVAL-IDQMESTEY
||..|.| .|..       .|.... . ..  .   ||..        |. ||.|..|||.|.|.               . |.||  .  ..|... . 
YCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMND

---------------------VGTELFMAPEV------KKNKEGI------CPYGVKSEIYSLGCVLSWMFT--HIYANFAHFTPL--------------
                     .||  .|||||       ..| ||       .|  |. .|| | ||  ..|  . |... .....              
TMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCD

----------------------VPPSIQKLALQMLSEKPEDRPTLDVVVREL
                      .|||. ||. .  ...||.||. . .. .|
KGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 86485.m00568.AA Pkinase 211-286 39 9.2e-18 63.89 Pfam 124-202 (293) Show / Hide 
Range on Protein: 211-286
Range on HMM: 124-202/293
Sequence Identity: 39% (33 aa)

IHSRKILIRDIKPDNILIDDNLIP----HISDFDVA----LIDQMESTEYVGTELFMAPEVKKNKEGICPYGVKSEIYSLGCVL
.||..|. ||.||.|||||.|  .    .|.|| .|    .  .   | ..||  .||||| .   |  .|| |. ..|.||.|
CHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---GGQYYGPKVDMWSCGCIL
Kinase 86485.m00568.AA ULK 176-286 29 1.1e-15 51.36 In-house 101-246 (329) Show / Hide 
Range on Protein: 176-286
Range on HMM: 101-246/329
Sequence Identity: 29% (43 aa)

YCQNGTLTSYVTNNPD----------LTNSQLIQIFINTCNLVMKIHSRKILIRDIKPDNILIDDNL------------IPHISDFDVALI---D---QM
||. |.| .|  .|            |. .. ||.|.  .|  . .|...|  |||||.||||...             .  |.||  |     |   | 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

ESTEYV------GTELFMAPEVKKNKEGICPYG-VKSEIYSLGCVL
  . .|      || |.|||.. ... . .||.  |. |.||||..
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIF
Kinase 86485.m00568.AA STE 176-286 25 1.2e-15 51.78 In-house 118-258 (359) Show / Hide 
Range on Protein: 176-286
Range on HMM: 118-258/359
Sequence Identity: 25% (37 aa)

YCQNGTLTSYVTNN----PDLT----------NSQLIQIFINTCNL-VMKIHSRKILIRDIKPDNILIDDNLIPHISDFDVALIDQM-------------
|. .|.|.. . ..     .|.           ||.. |   ..      .|| .|  |||||.|||.       ..|| |. . .              
YMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDC

------ESTEYVGTELFMAPEVKKN-KEG-ICPYGVKSEIYSLGCVL
      ...  |||  .||||| .. ..|   .|..|. |.||||..
IETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTI
Kinase 86485.m00568.AA ULK 176-286 30 2.3e-15 51.01 In-house 98-242 (324) Show / Hide 
Range on Protein: 176-286
Range on HMM: 98-242/324
Sequence Identity: 30% (44 aa)

YCQNGTLTSYVTNNPD---------LTNSQLIQIFINTCNLVMKIHSRKILIRDIKPDNILIDDNL------------IPHISDFDVALI-D-----QME
||. |.| .|  .|           |. .. ||.|.  ||  . .|...|  |||||.|||| ..             .  |.||  | . |     |. 
YCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQM

STEYV------GTELFMAPEVKKNKEGICPYG-VKSEIYSLGCVL
 ...|      || |.|||.. ... . .||.  |. |.||||..
CQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIF
Kinase 86485.m00568.AA Ciliate-E3 171-239 37 1.5e-14 42.07 In-house 80-150 (202) Show / Hide 
Range on Protein: 171-239
Range on HMM: 80-150/202
Sequence Identity: 37% (27 aa)

FVSSIYCQNGTLTSYVTNNPDLTNSQLIQIFINTCNLVMKIHSRKILIRDIKPDNILIDDNL---IPHISDF
|. . || || |. |.     .|   ...|.|.    .. ||...|   ||||||||.| |.   |  |.||
FIVQEYCSNGDLYHYIK-QQNKTQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKICDF
Kinase 86485.m00568.AA Ciliate-E1 187-280 24 4.3e-14 42.66 In-house 101-202 (202) Show / Hide 
Range on Protein: 187-280
Range on HMM: 101-202/202
Sequence Identity: 24% (25 aa)

TNNPDLTNSQLIQIFINTCNLVMKIHSRKILIRDIKPDNILIDDNLIPHISDFDVALIDQMESTEYV---GTELFMAPEVKKN-----KEGICPYGVKSE
.|. ..|  |..||...    .  .|. .|..|||||.||||... .  ..|| .... . ......   |    ..|. ..|      .   ... ||.
QNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSD

IY
||
IY
Kinase 86485.m00568.AA Ciliate-E2b 212-286 31 4.8e-14 39.22 In-house 119-200 (272) Show / Hide 
Range on Protein: 212-286
Range on HMM: 119-200/272
Sequence Identity: 31% (26 aa)

HSRKILIRDIKPDNILIDDNLIPHISDFDVA--LIDQME----STEYVGTELFMAPEVKK-NKEGICPYGVKSEIYSLGCVL
|...|. ||||| ||..| .  . . |. .|  . .. |     .  .||  .||||. .  . |  .|..|. |.|.| .|
HNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICL
Kinase 86485.m00568.AA CAMK 211-286 24 5.4e-14 40.77 In-house 195-324 (425) Show / Hide 
Range on Protein: 211-286
Range on HMM: 195-324/425
Sequence Identity: 24% (32 aa)

IHSRKILIRDIKPDNILIDDN-----------------LIPHISDFDVA--LID------------------------QMESTEYVGTELFMA-PEVKKN
.||..|  ||.||.|||.|||                     |.||  |  ...                            ....||  .|| ||| . 
CHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG

K----------EGICPYGVKSEIYSLGCVL
|          |.. .|| |. . |.|..|
KGHCNMQNATDEEKPYYGPKCDMWSCGVIL
S_TKc 86485.m00568.AA S_TKc 112-336 20 7.6e-12 -3.18 SMART 1-231 (231) Show / Hide 
Range on Protein: 112-336
Range on HMM: 1-231/231
Sequence Identity: 20% (54 aa)

PEGFEAIGYGDHSVVIKPIDNP---MFVFKYMQCDNPQDKLIKE----RLGETDHYPSILTIPHTKFVSSIY-----CQN--GTLTSYVTNNPD------
 |  . || |  ..| | ...     .  | .      .....|    .    ..   .. . ..   ...|     | .  |.| .|  ...       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LTNSQLIQIFINTCNLVMKIHSRKILIRDIKPDNILIDDNLIPHISDFDVALIDQMESTEYVGTELFMAPEVKKNKEGICPYGV-KSEIYSLGCVLSWMF
..  .   ..  .|. .  .||..|. ||.||.|||.|.     |.|| .| .     | ..||  .|||||        .||  |. ..|.||.|  |.
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILYEML

T------HIYANFAHFTPLVPPSIQKLALQMLSEKPEDRPTLDVVVR-E-----LDSI
.      .... | .     .|.   .  ..|   ||.|||   . . |        .
CGYPPFPQMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
TyrKc 86485.m00568.AA TyrKc 108-333 17 2e-06 -119.41 SMART 1-280 (280) Show / Hide 
Range on Protein: 108-333
Range on HMM: 1-280/280
Sequence Identity: 17% (51 aa)

LVLMPEGFEAIGYGDHSVVIKPIDNPMFVF-KYMQCDNPQDKLIKE-----RLG-ETDH---YPSILTIP-------HTKFVSSIYCQNGTLTSYVTNNP
..|     . .| |   .| | . . . |  | .. |  .  ...|     .|| . ..      . | .       .  ..   |. .| | .|  .. 
ITLG----KKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

D-LTNSQLIQIFINTCNLVMKIHSRKILIRDIKPDNILIDDNLIPHISDFDVALIDQMEST-------EYVGT----ELF-------MAPEVKKNK----
. |....|... .  ..    .||...  ||.   |.|...|..  ||||   |    ..        .|  .              ||||. . .    
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDF--GLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

----------------EGICPYGV-----KSEIYSLGCVLSWMFTHIYAN-----FAHFTPLVPPSIQKLALQMLSEKPEDRPTLDVVVREL
                 |  ||       .| .  . .| . .   . .|     |    .  |. . .. .|   |.||||||   .....
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF----VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 86485.m00568.AA Pkinase 300-333 16 0.806744 3.98 Pfam 259-293 (293) Show / Hide 
Range on Protein: 300-333
Range on HMM: 259-293/293
Sequence Identity: 16% (6 aa)

FTPLVPPSIQKLALQMLSEKPEDRPTLDVVVRE--L
| ...... ...   .|  .|..||| . ..    .
F-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF