Gene 86120.m00092 (T.vaginalis)
86120.m00092
Species: T.vaginalis
Alias: TvagK0655, 86120.m00092
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 86120.m00092.AA | Protein | None | 473 | None | Fasta, JSON |
| 86120.m00092.kin_dom | Protein Kinase Domain | None | 325 | None | Fasta, JSON |
Protein domains of 86120.m00092.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 86120.m00092.AA | DYRK | 142-466 | 35 | 1.7e-98 | 333.54 | In-house | 1-320 (320) | Show / Hide |
Range on Protein: 142-466 Range on HMM: 1-320/320 Sequence Identity: 35% (117 aa) YAVVGNLGHGQFGQVYAAIEVTSNLANKPKYAIKVARPGPMYRQQAFREVQILKQLQKLATPDELKYCIHFVDWFNFNDRLCIVNEHLYINLFEVIKRRG | ... .| | |||| . .. . .. . |||. | . . .|| .|..||. | . ||. ..|.|..| |.. |||| | | .||.|..|... YEILEYIGKGSFGQV---VKCWDH-KTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQ-DPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNH YRGL-PLQLIQSATRQLLFTLKTLEKC-NIVHSDIKPENILLKDD-KGSDIKLVDFGSARFIQQPASNYIQSRYYRAPEVVLGLDHDYKIDIWSAACVAF .|. .|.|... ..|.| || |.|. ||.| |.|||||.||. . |.||..||||. |. | . |||||.|||||| ||. ..|.||.|| |. FQGFFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILA ELFISMPLFPGQNEIHLLELIVAFLGEFPPEIVKKS--PRQNLFQNGKLKSEEQVCMENGTQPVYFQKYFQYDTMEEIILQYEYMFGNTPQARESERKRR |||. |||||.|| ..| .|. .|| .|.....|. .| . | . . ..| |. .| . ..|... . .. . ..... |.... . . . . ELFTGWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC---FMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQ-CDD LIFIDFLRKTLNLNPEKRLNATEALQHPFI . |.||..| |...|.||. . .|||||.. HQFKDFIKKCLQWDPHKRITPSQALQHPWF |
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| Kinase | 86120.m00092.AA | CMGC | 142-466 | 19 | 9.2e-80 | 261.6 | In-house | 1-513 (513) | Show / Hide |
Range on Protein: 142-466
Range on HMM: 1-513/513
Sequence Identity: 19% (101 aa)
YAVVGNLGHGQFGQVYAAIEVTSN----------LANKPKYAIKVARPGPMYRQQAF-------------REVQILKQLQ-KLATPD----------ELK
| ... .|.| .|.|| .. .| .. ..||| . . | || ||..|||.|. . . . .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKHHN
YCIHFVDWFNFND-----------------RLCIVNEHLYINLFEVIKRRG--YRG------------------------LPLQLIQSATRQLLFTLK--
.... |.| ... |..| |.. .|...||. |.| ... .|. ..|.| ||
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK
TLEKCN--IVHSDIKPENILLKDD------------------KGSDIKLVDFGSARFIQQP------------------------ASNYIQSRYYRAPEV
. . . |.| |.||||||. .. | .|. |||.||.. .. ..|...|.|||||.
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI
VLGLD----------HDYKIDIWSAACVAFELFIS--------MPLFPGQNE-----------IHLLELIVAFLGEFP---------------PE-----
|| ...||.||..|. .|.. |||||..| |. |..|. || .. .|
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNM
--------------------IVKKSPRQNLFQNGKLKSEEQVCMENGTQPVY-----------FQKYFQYDTMEEIILQYEYMFGNTPQARESERKRRLI
. ... |. ...|.... .| . | .. .| || . .. . | | | . ...
IKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVF-NW-IY---EEKFKSH-K-F-NH-Q--FKRKCCDPQ
FIDFLRKTLNLNPEKRLNATEALQHPFI
.||.| | | ..|.||. | .|||||..
AIDLLKKMLQYDPDKRITAEQALQHPYF
|
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| Kinase | 86120.m00092.AA | S_TKc | 142-466 | 23 | 6.7e-67 | 229.48 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 142-466
Range on HMM: 1-231/231
Sequence Identity: 23% (80 aa)
YAVVGNLGHGQFGQVYAAIEVTSNLANKPKYAIKVARPGPMYRQQAFREVQILKQLQKLATPDELKYCIHFVDWFNFNDRLCIVNEHLYI---NLFEVIK
| .. .|.| ||.|| .... . ..|||. . ... ||.||||. .. ... |.| |.|..| |.. .||..||
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK------EHIRREIQILKK--------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIK
RRGYRG----LPLQLIQSATRQLLFTLKTLEKCNIVHSDIKPENILLKDDKGSDIKLVDFGSARFIQQPASNYIQSRYYRAPEVVLGLDHDY-KIDIWSA
.||..| .| ... ..|.. |. . . .|.| |.||||||| . ||. |||.||.. . .. ...|.||||. ... |.|.||
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSC
ACVAFELFISMPLFPGQNEIHLLELIVAFLGEFPPEIVKKSPRQNLFQNGKLKSEEQVCMENGTQPVYFQKYFQYDTMEEIILQYEYMFGNTPQARESER
|. .|.. |.|| .. ....|.
GCILYEMLCGYPPFP--QMQMMFKKIG-------------------------------------------------------------------------
KRRLIFIDFLRKTLNLNPEKRLNATEALQ-------HPFI
..||.|| |. .||||. | |||| ||..
--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
|
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| Kinase | 86120.m00092.AA | YAK | 142-466 | 31 | 1.6e-65 | 221.44 | In-house | 1-347 (347) | Show / Hide |
Range on Protein: 142-466 Range on HMM: 1-347/347 Sequence Identity: 31% (112 aa) YAVVGNLGHGQFGQVYAAIEVTSNLANKPKYAIKVARPGPMYRQQAFREVQILKQLQKLATPDELKYCIHFV---DWFNFNDRLCIVNEHLYINLFEVIK | | || | |||| .|. . |.|| . | ||| |.|||. | . |.. | |.. | | . .|.| | | .||.| .| YIVLDMLGQGTFGQVVKC----QNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLK RRGYRGLPLQLIQSATRQLLFTLKTLEKCNIVHSDIKPENILLKDDKGSDIKLVDFGSARFIQQPASNYIQSRYYRAPEVVLGLDHDYKIDIWSAACVAF ..|. |||. | | | . || .|.| | |||||.|. .||..||||. . . |||.|.||.||.... || || |. QNKFCGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVA ELFISMPLFPGQNEIHLLELIVAFLGEFPPEIV---KKSPR---------------QNLFQNGK-----LKSEEQVCMENGTQPVYFQKYFQYDTMEEII ||| .|.||| | . |. || .| ... . . . | ||| .|... . ..| .|||| .. .|. ELFLGLPIFPGNSEYNQIKRIIDMLGYPPSWMIDQGRFKNKYFHCHDGSNSDDNNNNNNNNNGKPYYYIFKTKQDYQIDEKIQLKESKTYFQYKCLNDIK LQYEYMFGNTPQARESERKRRLIFIDFLRKTLNLNPEKRLNATEALQHPFI . . .| . ....| .||||. |.||| .| . | ||||| NYMYFKQFMRNQDDTKNNRHRDCFIDFINQLLQLNPRERWKPMQAMQHPFI |
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| Kinase | 86120.m00092.AA | DYRK2 | 142-398 | 36 | 1.9e-64 | 208.39 | In-house | 1-258 (318) | Show / Hide |
Range on Protein: 142-398 Range on HMM: 1-258/318 Sequence Identity: 36% (95 aa) YAVVGNLGHGQFGQVYAAIEVTSNLANKPKYAIKVARPGPMYRQQAFREVQILKQLQKLATPDELKYCIHFVDWFNFNDRLCIVNEHLYINLFEVIKRRG | .. .| | |||| . .| . |||. | . .|| .|..||. . . .|. |.| | | | .||. | | .|| | ||.. YEILEVIGKGSFGQVVKCYDH----KTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQD-KDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNH YRGLPLQLIQSATRQLLFTLKTLEKCNIVHSDIKPENILLKDDKGSDIKLVDFGSARFIQQ-PASNYIQSRYYRAPEVVLGLDHDYKIDIWSAACVAFEL . |. |||. ....| |. | | ||.| | |||||||| |.||..|||| .| | . |||||.|||||| ||. . ||.|| |.. || FQGFSLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAEL FISMPLFPGQNEIHLLELIVAFLGEFPPEIVKKS-----PRQNLFQNGKLKSEEQVCMENGTQ .. ||||| || . .. .|| |....... |...| | ... . .| ... YTGYPLFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCFRRKYFFNSHCFEWYCTFMTDHSM |
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| Kinase | 86120.m00092.AA | HIPK | 142-466 | 30 | 2.5e-53 | 166.06 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 142-466 Range on HMM: 1-329/329 Sequence Identity: 30% (104 aa) YAVVGNLGHGQFGQVYAAIE-VTSNLANKPKYAIKVARPGPMYRQQAFREVQILKQLQKLATPDELKYCIHFVDWFNFNDRLCIVNEHLYINLFEVIKRR | |. || | |||| . |. . |||. . | | | ||.||. |... .|| .. . . . |. . |.| | | ||.. | YEVLEFLGRGTFGQVVKCWKRGTNEMV-----AIKILKNHPYYARQGQIEVSILHCLSQEN-ADEYHF-VRAYECFHHKNHTCLVFEMLEQNLYDFQKQN GYRGLPLQLIQSATRQLLFTLKTLEKCNIVHSDIKPENILLKDDKGSD--IKLVDFGSARFIQQP-ASNYIQSRYYRAPEVVLGLDHDYKIDIWSAACVA . |||. | . | | |. | . ..| |.|||||.| | . .| .||||| . . . |.|||||||||..||| ..|.|| || KFMPLPLKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVI FELFISMPLFPGQNEIHLLELIVAFLGEFPPEIVKKSPRQN-LF--------QNGKLKSEEQVCMENGTQPVYFQKY--FQYDTMEEIILQYEYMFGNTP ||| ||.|| .| . | . . . .... ... .| . .|| |. . . . .|| | | | .. . . AELFLGWPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFDRDKQSKFRPWRLKHIEEHEQQTSVKSKEARKYIFNCLDDMPEVNMLVDPE----R QARESERKRRLIFIDFLRKTLNLNPEKRLNATEALQHPFI | |. | |.. |.| . ....||. |||.|||. QDYRVEKIDRREFVHVLKKMCTWDAHKRITPCEALNHPFV |
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| Kinase | 86120.m00092.AA | DYRK1 | 142-380 | 34 | 1.9e-50 | 173.89 | In-house | 1-236 (321) | Show / Hide |
Range on Protein: 142-380 Range on HMM: 1-236/321 Sequence Identity: 34% (83 aa) YAVVGNLGHGQFGQVYAAIEVTSNLANKPKYAIKVARPGPMYRQQAFREVQILKQLQKLATPDELKYCIHFVDWFNFNDRLCIVNEHLYINLFEVIKRRG | . .| | |||| | . .. |||. . . .|| |...| | . ... | .| | | . ||.| | | ||..... YEIDSLIGKGSFGQVVKAYDH----QEQEYVAIKIIKNKKPFYNQAQIEIRLL-ELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTH YRGLPLQLIQSATRQLLFTLKTLE--KCNIVHSDIKPENILLKDDKGSDIKLVDFGSARFIQQPASNYIQSRYYRAPEVVLGLDHDYKIDIWSAACVAFE .|| | |.. .|.. .| . .|.| |.||||||| | | ||..||||. | .|||||.||.|||.||.. | .||.|| |. | FRGVSLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVE LFISMPLFPGQNEIHLLELIVAFLGEFPPEIVKKSPRQNLF . . ||| |.||. .. || || | ... ..|. . MHTGEPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKY |
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| Kinase | 86120.m00092.AA | PRP4 | 142-374 | 36 | 2.6e-50 | 173.47 | In-house | 1-232 (320) | Show / Hide |
Range on Protein: 142-374 Range on HMM: 1-232/320 Sequence Identity: 36% (85 aa) YAVVGNLGHGQFGQVYAAIEVTSNLANKPKYAIKVARPGPMYRQQAFREVQILKQLQKL-ATPDELKYCIHFVDWFNFNDRLCIVNEHLYINLFEVIKRR |.|.| | | |. | . . | . . |||. | .. .. ||. ||. | . ... . |. . ||. .|.| | . || ||.|. YRVYGYCGQGVFSNVCRCRDQT---RGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKY G-YRGLPLQLIQSATRQLLFTLKTLEKCNIVHSDIKPENILLKDDKGSDIKLVDFGSARFIQ-QPASNYIQSRYYRAPEVVLGLDHDYKIDIWSAACVAF | || | . | ..||. || | ||||.| |||| ||| .| . .|..||||| |. . | .||.|||||...| .|| ||.||..| . GKDVGLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNILVNESK-NTLKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLY ELFISMPLFPGQNEIHLLELIVAFLGEFPPEIVKKS ||. .|||. | | |. | .| ...|. ELYTGKIMFPGKTNNHMLKLFMDYKGKMPNKMIRKG |
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| Kinase | 86120.m00092.AA | Pkinase | 142-359 | 24 | 3.7e-40 | 143.08 | Pfam | 1-230 (293) | Show / Hide |
Range on Protein: 142-359 Range on HMM: 1-230/293 Sequence Identity: 24% (59 aa) YAVVGNLGHGQFGQVYAAIEVTSNLANKPKYAIKVARPGPMYRQQ---AFR--EVQILKQLQKLATPDELKYCIHFVDWFNFNDRLCIVNEHLYI----- | ... .| | ||.|| .... .. ..|.|. . .. ..| |.||.| |. .. . . ||| .|....| |.. YHIGRKIGSGSFGCVYKCHHKGTGK----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-------HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVM NLFEVIKRRGYRGL--PLQLIQSATRQLLFTLKTLEKCNIVHSDIKPENILLKDDKGSD---IKLVDFGSARFI---QQPASNYIQSRYYRAPEVVL-GL ||..|... .... . . ... .|.| |. . ...|.| |.||||||.. ..| .|. |||.|... .. .. . ...|.||||.. | DLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQ DHDYKIDIWSAACVAFELFISMPLFPGQ------NEIHLLELI ....|.|.||. |. .|.. |.|||. ........| YYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRI |
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| Kinase | 86120.m00092.AA | CLK | 142-283 | 28 | 5.7e-36 | 104.81 | In-house | 1-149 (350) | Show / Hide |
Range on Protein: 142-283 Range on HMM: 1-149/350 Sequence Identity: 28% (44 aa) YAVVGNLGHGQFGQVYAAIEVTSNLANKPKYAIKVARPGPMYRQQAFREVQ-ILKQLQKLATPDELKY--CIHFVDWFNF-NDRLCIVNEHLYINLFEVI | .| .|| | || |. |. . | ..|.|. | || .| |.. |.|.... |. . |.. |||.. ... ||| | . ...... YEIVCTLGEGTFGKVV---ECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFM KRRG------YRGLPLQLIQSATRQLLFTLKTLEKCNIVHSDIKPENILLKD | . |...|.. |.. ..||. .| |.. ..| | |||||.. | KSNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICFVD |
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| Kinase | 86120.m00092.AA | GSK | 256-364 | 42 | 4.5e-34 | 101.03 | In-house | 124-236 (328) | Show / Hide |
Range on Protein: 256-364 Range on HMM: 124-236/328 Sequence Identity: 42% (48 aa) QLLFTLKTLEKCNIVHSDIKPENILLKDDKGSDIKLVDFGSAR-FIQ---QPASNYIQSRYYRAPEVVLGLDH-DYKIDIWSAACVAFELFISMPLFPGQ |.. |. |.. .|.| ||||.|||. .|.|. |. |||||. . .| || |||||||| .| . . .||.||. || .|... |||||. QMFRGLAYLHSHGICHRDIKPQNILVDPDTGV-LKICDFGSAKQLEPNKNEPNISYICSRYYRAPELIFGCTNYTCQIDVWSCGCVMAEMLKGQPLFPGD NEIHLLELIVAFLG .... |..|. || SSVDQLVEIIKMLG |
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| Kinase | 86120.m00092.AA | CAMK | 147-338 | 17 | 1e-33 | 105.45 | In-house | 1-325 (425) | Show / Hide |
Range on Protein: 147-338
Range on HMM: 1-325/425
Sequence Identity: 17% (58 aa)
NLGHGQFGQVYAAIEV-TSNLAN-------KPKYAIKV-----ARP------------------------GPMYRQQAFREVQILKQLQKLATPDE---L
||.|.||.|. .|. | .. . . |.|||. .. | |.. .||..|.|.||.. ..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGI---GNKLDH
KYCIHFVDWFN------------FNDR--------LCIVN---EHLYIN-----LFEVIKRRGY-------------RGLPLQLIQSATRQLLFTLKTLE
. |.. ... . .. ...| |. ||. |...|. . .. . . ||.. .. .
PNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCH
KCNIVHSDIKPENILLKDDKG---------------SDIKLVDFGSARFIQQ--------------------------PASNYIQSRYYRA-PEVVLG--
..|||| |.||||||| |... .||..||| |..... . . . . .| | |||..|
SHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKG
------------LDHDYKIDIWSAACVAF
...|.|.||. .. .
HCNMQNATDEEKPYYGPKCDMWSCGVILY
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| Kinase | 86120.m00092.AA | CLK | 288-390 | 29 | 5.8e-23 | 65.05 | In-house | 185-295 (350) | Show / Hide |
Range on Protein: 288-390 Range on HMM: 185-295/350 Sequence Identity: 29% (33 aa) DIKLVDFGSAR---FIQQPASNYIQSRYYRAPEVVLGLDHDYKIDIWSAACVAFELFISMPLFPGQNEIHLLELIVAFLG-EFPPEIVKKSP----RQNL .|...|||||. | . | ...| ||||||.||| .. |.|| .|. ||| . ||.. ... |... .| .| ... | HICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRTRRFKVKQKY FQNGKLKSEEQ |....| .. FYHNRLDWDWH |
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| Kinase | 86120.m00092.AA | CAMK | 440-466 | 40 | 6.8e-11 | 30.61 | In-house | 399-425 (425) | Show / Hide |
Range on Protein: 440-466 Range on HMM: 399-425/425 Sequence Identity: 40% (11 aa) IDFLRKTLNLNPEKRLNATEALQHPFI .|..|| |. .||||......|.||.. KDLIRKMLQVDPEKRMTIEQCLNHPWM |
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| Kinase | 86120.m00092.AA | Pkinase | 439-466 | 39 | 1.2e-09 | 35.21 | Pfam | 266-293 (293) | Show / Hide |
Range on Protein: 439-466 Range on HMM: 266-293/293 Sequence Identity: 39% (11 aa) FIDFLRKTLNLNPEKRLNATEALQHPFI ..||... |...|.||..|...||||.. CKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 86120.m00092.AA | DYRK2 | 439-466 | 39 | 1.7e-09 | 26.66 | In-house | 291-318 (318) | Show / Hide |
Range on Protein: 439-466 Range on HMM: 291-318/318 Sequence Identity: 39% (11 aa) FIDFLRKTLNLNPEKRLNATEALQHPFI ||||... . |..|. . .||.||.| FIDFIKRCFEWDPSERMTPSQALKHPWI |
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| Kinase | 86120.m00092.AA | GSK | 440-466 | 48 | 2.6e-09 | 23.99 | In-house | 302-328 (328) | Show / Hide |
Range on Protein: 440-466 Range on HMM: 302-328/328 Sequence Identity: 48% (13 aa) IDFLRKTLNLNPEKRLNATEALQHPFI ||.. |.| .|.|||.. ||..||| IDLISKCLVYDPKKRLSPLEACAHPFF |
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| Kinase | 86120.m00092.AA | CLK | 438-466 | 44 | 1.3e-07 | 18.14 | In-house | 322-350 (350) | Show / Hide |
Range on Protein: 438-466 Range on HMM: 322-350/350 Sequence Identity: 44% (13 aa) IFIDFLRKTLNLNPEKRLNATEALQHPFI ...| .|| | | ||. . .|||||| QLFDLIRKMLEYDPSKRITCKDALQHPFF |
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| Kinase | 86120.m00092.AA | PRP4 | 441-466 | 57 | 1.4e-07 | 23.88 | In-house | 295-320 (320) | Show / Hide |
Range on Protein: 441-466 Range on HMM: 295-320/320 Sequence Identity: 57% (15 aa) DFLRKTLNLNPEKRLNATEALQHPFI |.| | | | |.|| |||.|||| DLLDKCLMLDPKKRITCNEALKHPFI |
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| Kinase | 86120.m00092.AA | TyrKc | 142-466 | 14 | 4.1e-07 | -107.64 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 142-466
Range on HMM: 1-280/280
Sequence Identity: 14% (53 aa)
YAVVGNLGHGQFGQVYAAIEVTSNLANKPKYAIKVARPGPMYRQQAFREVQILKQL--QKLATPDELKYCIHFVDWFNFN-------DRLCIVNEHL-YI
||.|.||.|| .. . |.|. ... |. || .|...| . . . .. . |.|| |. .
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA--REDFMREARIMCKLGGHH-------PNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHG
NLFEVIKRRGYRGLPLQLIQSATRQLLFTLKTLEKCNIVHSDIKPENILLKDDKGSDIKLVDFGSARFIQQP-----ASNYI------QSR-----YYRA
.| . ..... . |... | | |.. |..| |. |.|..... .| ||| .|.| .. |. ... |
DLKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA
PEVVLGLDH--DYKIDIWSAACVAFELFIS-MPLFPG-----QNEIHLLELIVAFLGEFPPEI----VKKSPRQNLFQNGKLKSEEQVCMENGTQPVYFQ
||. .. | |.|| . .|.| .. || . ....|.. . .|.
PECI--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------------
KYFQYDTMEEIILQYEYMFGNTPQARESERKRRLIFIDFLRKTLNLNPEKRLNATEALQHPFI
. . .. .. . .||.| . .| | ..
---------------------------FVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF
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| Kinase | 86120.m00092.AA | GSK | 142-200 | 34 | 6e-06 | 13.54 | In-house | 1-61 (328) | Show / Hide |
Range on Protein: 142-200 Range on HMM: 1-61/328 Sequence Identity: 34% (22 aa) YAVVGNLGHGQFGQVYAAIEVTSNLANKPK----YAIKVARPGPMYRQQAFREVQILKQLQKL | ||| || || |. . . .| . .||| . . |. . ||.||.|.| || YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIKKVWQDKRYK--CNRELQIMKMLGKL |
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| Kinase | 86120.m00092.AA | DYRK1 | 439-466 | 35 | 2.6e-05 | 14.08 | In-house | 294-321 (321) | Show / Hide |
Range on Protein: 439-466 Range on HMM: 294-321/321 Sequence Identity: 35% (10 aa) FIDFLRKTLNLNPEKRLNATEALQHPFI | | ... |. .|..|.. .||||.|. FKDLIKRMLQYDPKQRITPYYALQHSFF |
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