Gene 86393.m00092 (T.vaginalis)

86393.m00092

Species: T.vaginalis
Alias: 86393.m00092, TvagK0831
External Links:
Annotation:

Classification

Group: Other
Family: SCY1

Sequence

Name Sequence Type Origin Length Description Download
86393.m00092.AA Protein None 709 None Fasta, JSON
86393.m00092.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 86393.m00092.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 86393.m00092.AA NZAK 183-272 30 4.4e-13 39.77 In-house 235-329 (329) Show / Hide 
Range on Protein: 183-272
Range on HMM: 235-329/329
Sequence Identity: 30% (29 aa)

SISFCSPELVGNKQITTTSDVFSYGSLLISMLLKRIA---FSPSNSQDLVA-QAQTAPMQIPPNTPAELKDLLLQCLNIDPNQR-PDFSTIAKCN
.. .  ||   |  |.  |||.| | . . |         .||     .|. | .    ||| . |  .||.. ||. |||..|  ||| .    
THHYMAPENKNNHRINEKSDVWSFGCTVWQMFGYNPPNTIYSPKEMASMVSDQKFNYIPQIPFHVPDKMKDFITQCWDIDPKKRPKDFSHMIEKL
Kinase 86393.m00092.AA Pkinase 186-263 18 3.4e-12 44.21 Pfam 177-282 (293) Show / Hide 
Range on Protein: 186-263
Range on HMM: 177-282/293
Sequence Identity: 18% (20 aa)

FCSPELVG-NKQITTTSDVFSYGSLLISMLLKRIAFSPS------NSQDLVAQAQTAPMQIPPNTP---------------------AELKDLLLQCLNI
...||..  .. ... .|..|.| .|. ||..|  |. .      . . ....   .|   .  ..                      |.||..  ||. 
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

DPNQRP
||..||
DPKKRP
S_TKc 86393.m00092.AA S_TKc 9-275 16 1.8e-11 -8.82 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-275
Range on HMM: 1-231/231
Sequence Identity: 16% (48 aa)

YENINPLFTLDFWNVHSANKKETGEKVSLWVIDQDKLKKSVSKKADRENYLKSCMDSIQQMRRLMHPHILKIFEFNENISQLAFAAEPVQY-----SFQY
|| ....    |  |. . .|.||..| . .|.                  .. .  || ...  ||.| |.... .. . | .  | .           
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYI

EAN--------FSMDEVQYIALQLAETFEFLHTGAKISYLGLSQSTVVLTKSFDVKFCQFNFASPIINEQGLVGSRIGAFANLPTQPSISFCSPELVGNK
. .        |.  ...... |...  |..|   .| .  |  . . |..   .| | | .|  .                     .  ...||..   
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL----------------TTFCGTPWYMAPEVL---

QITT-TSDVFSYGSLLISMLLKRIAFSPSNSQDLVAQAQTAPMQIPPNTPAELKDLLLQCLNIDPNQRPDFSTIAK------CNAFL
. ..  .|. | | .|. ||  .  |.  . | .  .            . |.||.. .||. ||..||    . .      |  ..
GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 86393.m00092.AA TKL 183-268 16 2.3e-11 37.17 In-house 236-360 (364) Show / Hide 
Range on Protein: 183-268
Range on HMM: 236-360/364
Sequence Identity: 16% (21 aa)

SISFCSPELVGNK----------------QITTTSDVFSYGSLLISMLLKRIAFS-PSNSQ-----------DLVAQAQTAPMQI-----------PPNT
.. ...||.  ..                . .. .||.|.| .|  .|  .. .. . ...            .|.. .  |              .|..
TPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDC

PAELKDLLLQCLNIDPNQRPDFSTI
| ..|.|. .| . ||..|| |..|
PPSMKKLMQDCWDHDPEKRPSFQEI
Kinase 86393.m00092.AA SCY1 21-97 26 4.5e-10 31.16 In-house 1-77 (337) Show / Hide 
Range on Protein: 21-97
Range on HMM: 1-77/337
Sequence Identity: 26% (21 aa)

WNVHSANKKETGEKVSLWVIDQDKLKKSVSKKADRENYLKSCMDSIQQMRRLMHPHILKIFEFNENISQ-LAFAAEPV
| .|.. ||.||...|..| |   . | ..|..  |.       ..... || ||.||....  |. .  ...|.|..
WKIHNGTKKYTGQECSVFVFDKKNIEK-WHKDSWWEEICEFLKKQAKRLKRLRHPNILQYIHPLEESKDCMMYATEEI
Kinase 86393.m00092.AA TK 223-272 20 1.8e-09 27.09 In-house 400-486 (486) Show / Hide 
Range on Protein: 223-272
Range on HMM: 400-486/486
Sequence Identity: 20% (18 aa)

SN--------SQDLVAQAQT---------------APMQIPPNTP--------------AELKDLLLQCLNIDPNQRPDFSTIAKCN
||         |... . ..                .|  ||. |              .|. ||..|| . ||..||.||.. .. 
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 86393.m00092.AA Frk 184-275 30 3.1e-09 27.8 In-house 166-260 (260) Show / Hide 
Range on Protein: 184-275
Range on HMM: 166-260/260
Sequence Identity: 30% (29 aa)

ISFCSPELVGNKQITTTSDVFSYGSLLISML-LKRIAFSP-SNSQDLVAQAQTAPMQIPPNTPAELKDLLLQCLNIDPNQRPDFSTIA-KCNAFL
| .  || .  .. |. |||.|.| ||  ..   |. ..   | . |   ..   |  ||| | .| ...|.| . ||..|| | |.  | . ..
IKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase 86393.m00092.AA TKL-Unique 183-268 27 4e-09 28.51 In-house 189-286 (290) Show / Hide 
Range on Protein: 183-268
Range on HMM: 189-286/290
Sequence Identity: 27% (27 aa)

SISFCSPELVGN--KQITTTSDVFSYGSLLISMLLKRI---------AFSPSNSQDLVAQA-QTAPMQIPPNTPAELKDLLLQCLNIDPNQRPDFSTI
|.   .||.  .  .|... |||.|.|  |. ..   |         ....     .|..     .  ||.. | |..||. || . || ||| |..|
SFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEI
Kinase 86393.m00092.AA RTKE 186-272 19 7.7e-09 26.22 In-house 193-293 (293) Show / Hide 
Range on Protein: 186-272
Range on HMM: 193-293/293
Sequence Identity: 19% (20 aa)

FCSPELVGNKQITTTSDVFSYGSLLISML-LKRIAFSPSNSQDLVAQAQTAPM-------------QIPPNTPAELKDLLLQCLNIDPNQRPDFSTIAKC
. .||.   .  .. |||..|| |.  ..    . .   . | .. . ... |               |.  |. . .|  .|| |.|  ||.| ...  
WWAPEVWKDQHFSFKSDVWAYGCLCWEVWNNGQMPYAHMDDQQFMQRIVQCQMPSGGHLGDHEPVHAPPVHCPPWADRLMQWCLCINPEHRPNFAQLYQM

N
 
W
Kinase 86393.m00092.AA Pkinase_Tyr 237-274 42 1e-08 30.15 Pfam 235-270 (270) Show / Hide 
Range on Protein: 237-274
Range on HMM: 235-270/270
Sequence Identity: 42% (16 aa)

MQIPPNTPAELKDLLLQCLNIDPNQRPDFSTIAKCNAF
| .|.|.|.|. ||..|| . ||..|| || |   . .
MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL
Kinase 86393.m00092.AA MLK 239-272 41 1.9e-08 25.53 In-house 258-291 (291) Show / Hide 
Range on Protein: 239-272
Range on HMM: 258-291/291
Sequence Identity: 41% (14 aa)

IPPNTPAELKDLLLQCLNIDPNQRPDFSTIAKCN
||.. |. .| |. || | ||..||.|. | .  
IPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 86393.m00092.AA TKL-ciliate1 189-272 21 2.1e-08 24.84 In-house 188-279 (279) Show / Hide 
Range on Protein: 189-272
Range on HMM: 188-279/279
Sequence Identity: 21% (20 aa)

PELVGNKQITTTSDVFSYGSLLISMLLKRIAF----SPSNSQDLVAQAQ----TAPMQIPPNTPAELKDLLLQCLNIDPNQRPDFSTIAKCN
| .  |..|..  |...|| ..  .  .   |    |  | . ..          |  |.  .|... .|.  |. ..||.||.|. |    
PHIFPNYPINEKIDIYAYGIVMYILCFRKTPFQQKMSVINIMCYWCEFPGRPNLGPQFIHFDCPQNFHNLMMRCWCQNPNKRPNFNEIIQIL
Kinase 86393.m00092.AA Ciliate-E2 188-274 18 2.2e-08 24.88 In-house 255-365 (365) Show / Hide 
Range on Protein: 188-274
Range on HMM: 255-365/365
Sequence Identity: 18% (22 aa)

SPELVGNKQ---------ITTTSDVFSYGSLLISMLLKRIAFSPSNSQDLVAQAQTAPMQIPPN------------------TPAELKDLLLQ----CLN
.|| ...|.          .. .|..| | .|  || ..  |          | .  . ..|..                   . | |||. .    .|.
APEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQ

IDPNQRPD-FSTIAKCNAF
 ||..|.. .. | .   |
KDPEKRITGWEQILNHPWF
Kinase 86393.m00092.AA TyrKc 39-274 14 2.2e-05 -135.71 SMART 1-280 (280) Show / Hide 
Range on Protein: 39-274
Range on HMM: 1-280/280
Sequence Identity: 14% (48 aa)

VIDQDKL-------------------KKSVSKKADRENYLKSCMDSIQQMRRL--MHPHILK--------------------IFEFNENISQLAFAAEPV
.   .||                   |.  . .      ..  |. .. |..|   ||.|..                    ..|. .. . . .  .. 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

QYSFQYEANFSMDEVQYIALQLAETFEFLHTGAKISYLGLSQSTVVLTKSFDVKFCQFNFASPII-----------NEQG-----------LVGSR----
         ..|..  ....| |.  |.||                                ..|           .|..            ...     
PK-------LCMKDLLSFCWQIACGMEYLHSK------------------------------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG

----IGAF-----AN--LPTQPSISFCSPELVGNKQITTTSDVFSYGSLLISM--LLKRIAFSPSN-------SQDLVAQAQTA-PMQIPPN--------
             ..  ||    |  ..||    .  || |||.|.|   . |  .. . .  ...        |..... ..   | .|||        
ESKDYYRKKEHKGGKTMLP----IRWMAPECINYGKFTTKSDVWSFG---VCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVC

TPAELKDLLLQCLNIDPNQRPDFSTIAKCNAF
 |.|. .. .|| . ||..|| ||.|  .  |
CPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 86393.m00092.AA Pkinase 66-127 21 0.000593 15.06 Pfam 51-125 (293) Show / Hide 
Range on Protein: 66-127
Range on HMM: 51-125/293
Sequence Identity: 21% (16 aa)

IQQMRRLMHPHILKIFEFNENISQLAFAAEPVQY-----SFQ------YEANF--SMDEVQYIALQLAETFEFLH
|| |.|| ||.|...... |. . . .  | ..      .        .. .|  |..|.. ...|...  |..|
IQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCH
Kinase 86393.m00092.AA SCY1 179-274 21 0.002027 7.81 In-house 219-337 (337) Show / Hide 
Range on Protein: 179-274
Range on HMM: 219-337/337
Sequence Identity: 21% (26 aa)

PTQPSISFCSPELVGN-------------KQITTTSDVFSYGSLLISML--LKRIAFSPSNS----QDLVAQAQTAPMQIPPNTPAELKDL----LLQCL
| ||. ..  || . .                |. ||.|| | |  ...  .|...   ||.       . |  ..  .. ...| ||...        |
PCQPNPDWLAPEYIHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQITCNSNPYSTFHRYMEQWNAMSHCWWDHIPKELQEHLGHCYCHLL

NIDPNQRPDFSTIAKCNAF
. ||..|||.... .   |
HQDPTCRPDPQQFLQHCYF
Kinase 86393.m00092.AA Ciliate-E2 23-127 16 0.013509 4.71 In-house 15-177 (365) Show / Hide 
Range on Protein: 23-127
Range on HMM: 15-177/365
Sequence Identity: 16% (27 aa)

VHSANKKETGEKVSLWVIDQDKLKKS-----------VSKKADRENYLKSCMDSIQQMR----------------RLMHPHILKIFEFNE--NISQLAFA
|  .......... . .|| .|. ..           . .|  ..| ... .  |..||                .| ||.|.|..|. .  . . . . 
VYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLV

AEPVQYS--FQYEA--------------NFSMDEVQYIALQLAE---------------TFEFLH
 | .|.   |.|                .|.. |..||  |...                .|.||
MEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLH