Gene 88601.m00557 (T.vaginalis)

88601.m00557

Species: T.vaginalis
Alias: 88601.m00557, TvagK0781
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
88601.m00557.AA Protein None 224 None Fasta, JSON
88601.m00557.kin_dom Protein Kinase Domain None 125 None Fasta, JSON

Protein domain

Protein domains of 88601.m00557.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 88601.m00557.AA CAMK 127-206 17 7.4e-16 46.89 In-house 197-334 (425) Show / Hide 
Range on Protein: 127-206
Range on HMM: 197-334/425
Sequence Identity: 17% (24 aa)

EKGIKHCDLKPDNIVVDGDM-----------------IPHIIDWDDSTTRFSLS-------------------------INERHGTIPFAA-PEIFSA--
...| |.||||.|| .| ..                    |||.  ..  .. .                          ... || ...| ||...   
SHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKG

-----------QRK--CESDIFSFGAIMFNMITECYPF
           ..    ..|. | | |.. | . ..||
HCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPF
Kinase 88601.m00557.AA Ciliate-E2 83-206 19 2.7e-15 48.93 In-house 111-296 (365) Show / Hide 
Range on Protein: 83-206
Range on HMM: 111-296/365
Sequence Identity: 19% (38 aa)

ILMDYIPGNTLTKLI-------------NGGYVGNRVKRLYMLEIFA---------------AIAYQLTLMREKG-IKHCDLKPDNIVVDGDMIPHIIDW
. |.|. |..| ..|               .|   .  . .| .|.                |. |    . .|. | | |.||.||..     . |||.
LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEY----LHSKNNIIHRDIKPENILF-----IKIIDF

DDSTTRFSLSINERH---------------------------------GTIPFAAPEIFSAQRK----------CESDIFSFGAIMFNMITECYPF
  |.     ..|..|                                 || .. ||||.. .             ..||.|.| |.. |..  .||
GLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF
Kinase 88601.m00557.AA Ciliate-E2-Unclassified 85-206 20 4.1e-15 48.89 In-house 100-270 (352) Show / Hide 
Range on Protein: 85-206
Range on HMM: 100-270/352
Sequence Identity: 20% (35 aa)

MDYIPGNTLTKLIN------------------GGYVGNRVKR-----LYMLEIFAAIAYQLTLMREKGIKHCDLKPDNIVVDGDM---IPHIIDWDDST-
|.|..|..| . |.                  .  .  .  .      |. .|  .. |   | ....| | |.||.||..| ..    . |||.  |  
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEY---LHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKK

------------TRFSLSINERH----GTIPFA----APEIFSA-QRK----CESDIFSFGAIMFNMITECYPF
            ....  ....     ||. .     |||..   .       ..||.|.| |.. |..  |||
YQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPF
Pkinase 88601.m00557.AA Pkinase 82-206 23 1.8e-12 45.2 Pfam 76-212 (293) Show / Hide 
Range on Protein: 82-206
Range on HMM: 76-212/293
Sequence Identity: 23% (34 aa)

WILMDYIPGN----TLTKLIN---GGYV--GNRVKRLYMLEIFAAIAYQLTLMREKGIKHCDLKPDNIVVDGDMIP----HIIDWDDST---TRFSLSIN
.. |.| .|      |  .|    .| .    .. . ||..|. ...|    . ..|| |.||||.|| .| .. .    .|.|.  .    .  .   .
YMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEY----CHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MT

ERHGTIPFAAPEI--FSAQRKCESDIFSFGAIMFNMITECYPF
 . ||....|||.  ..     ..|..|.| |.. |..   ||
TFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPF
S_TKc 88601.m00557.AA S_TKc 13-224 18 7.3e-11 -17.62 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-224
Range on HMM: 1-231/231
Sequence Identity: 18% (48 aa)

VQEIYRAGNGGNGTCW--ILKIDDHYRVLKRLFNRSGTKISEMFKNELKFQI---PLSPIYYDNSQNHPGERFDWILMDYIPG---NTLTKLINGGY---
 . .   | |. |...  . | ....  .|..         |....|..      |    .||  |.     . .. |.|..|   . .. . . |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKKHHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---VGNRVKRLYMLEIFAAIAYQLTLMREKGIKHCDLKPDNIVVDGDMIPHIIDWDDSTTRFSLSINERHGTIPFAAPEIFSAQRKC-ESDIFSFGAIMF
       . | || .|. |..|    . ..|| |.||||.|| .|      |.|   ..       .   ||  . |||..  .  . ..|. |.| |..
RFPFPE-HARFYMYQICCALEY----CHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILY

NMITECYPFASAYMT--------------KAGLQ----------SLA-------SQFP
 |.. . ||   ...              .  ||           |.        .. 
EMLCGYPPFP-QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase 88601.m00557.AA TKL-Unique 83-206 23 1.3e-08 26.64 In-house 77-234 (290) Show / Hide 
Range on Protein: 83-206
Range on HMM: 77-234/290
Sequence Identity: 23% (37 aa)

ILMDYIPGNTLTKLIN----------GGYVGNRVKRLYMLEIFAAIAYQLTLMREKGIKHCDLKPDNIVVDGD-----MIPHIIDWDDSTTRF--SLSIN
| |.|.||..| ....            .  |  .|. | .  |   | |     . | |.|||. |. || .     .   |.|   |...   . ..|
IVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTN

ERH---------GTIPFAAPEIFSA---QRKCESDIFSFGAIMFNMITECY------PF
 .|         |..  .|||...    |. . ||..|||...  ..| .       |.
NEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPY
Kinase 88601.m00557.AA TKL 82-207 20 1.4e-08 27.01 In-house 114-290 (364) Show / Hide 
Range on Protein: 82-207
Range on HMM: 114-290/364
Sequence Identity: 20% (37 aa)

WILMDYIPGNT-LTKLINGGYVGNRVKRLYMLEIFAAIAYQLTLMR-----EKGIKHCDLKPDNIVVDGDMI--------------PHIIDWDDSTTRF-
.| |.|.|| . |  |.        ..   .|.|  ...| |  |.      ..| |.|||..|| || ..               . | |   |.. . 
CIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNY-LHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQ

--SLSINE------------------RHGTIPFAAPEIFSAQRK-----------------CESDIFSFGAIMFNMITECYPFA
  . . ..                  . ||. . |||..  | .                   .|..||| ... ..| | |..
SGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY
Kinase 88601.m00557.AA Ciliate-E3 170-200 37 2.3e-07 19.35 In-house 171-202 (202) Show / Hide 
Range on Protein: 170-200
Range on HMM: 171-202/202
Sequence Identity: 37% (12 aa)

TIPFAAPEIFS-AQRKCESDIFSFGAIMFNMI
|. .||||.   .| . |||. | ||..  ..
TPFYAAPEQNDQQQISKESDYYSVGAVFCQLC
Kinase 88601.m00557.AA CAMKL 169-206 35 2.4e-07 19.34 In-house 195-236 (297) Show / Hide 
Range on Protein: 169-206
Range on HMM: 195-236/297
Sequence Identity: 35% (15 aa)

GTIPFAAPEIFSA--QRKC--ESDIFSFGAIMFNMITECYPF
|. |..|||||.   .. .  . || | | |...|..  .||
GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPF
Kinase 88601.m00557.AA CAMK-Unique 169-209 30 9.5e-05 11.38 In-house 237-296 (363) Show / Hide 
Range on Protein: 169-209
Range on HMM: 237-296/363
Sequence Identity: 30% (18 aa)

GTIPFAAP--------------EIFSAQR---KC--ESDIFSFGAIMFNMITECYPFASA
||....||              |.  .|.   .|   ||| | |.||. |.. | ||...
GTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCE
Kinase 88601.m00557.AA MARK 169-206 37 0.000147 11.01 In-house 167-206 (262) Show / Hide 
Range on Protein: 169-206
Range on HMM: 167-206/262
Sequence Identity: 37% (15 aa)

GTIPFAAPEIFSAQRKC--ESDIFSFGAIMFNMITECYPF
|| |..|||||. .. .  . || | | ... |.. ..||
GTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPF
Kinase 88601.m00557.AA Ciliate-E9 125-143 45 0.000472 8.41 In-house 127-146 (298) Show / Hide 
Range on Protein: 125-143
Range on HMM: 127-146/298
Sequence Identity: 45% (9 aa)

MREKG-IKHCDLKPDNIVVD
|  .. | | ||||.|...|
MHQYQNICHRDLKPENMLID
Kinase 88601.m00557.AA MARK 127-146 45 0.000558 9.09 In-house 122-141 (262) Show / Hide 
Range on Protein: 127-146
Range on HMM: 122-141/262
Sequence Identity: 45% (9 aa)

EKGIKHCDLKPDNIVVDGDM
.|.| |.|.||.|| .| ..
SKNIVHRDIKPENILIDENG
Kinase 88601.m00557.AA Ciliate-E9 188-208 52 0.000618 8.03 In-house 207-227 (298) Show / Hide 
Range on Protein: 188-208
Range on HMM: 207-227/298
Sequence Identity: 52% (11 aa)

DIFSFGAIMFNMITECYPFAS
|||| | | | |..  ||| .
DIFSAGCILFMMVMNQYPFFH
Kinase 88601.m00557.AA CAMKL 127-152 42 0.001179 7.37 In-house 145-172 (297) Show / Hide 
Range on Protein: 127-152
Range on HMM: 145-172/297
Sequence Identity: 42% (12 aa)

EKGIKHCDLKPDNIVVDGDM--IPHIID
..|| | |.||.|| .| ..     |||
SHGIVHRDIKPENILLDENGNNNIKIID
Kinase 88601.m00557.AA Ciliate-E3 127-143 70 0.001413 7.36 In-house 121-137 (202) Show / Hide 
Range on Protein: 127-143
Range on HMM: 121-137/202
Sequence Identity: 70% (12 aa)

EKGIKHCDLKPDNIVVD
|| | | |.||||| ||
EKNIIHSDIKPDNILVD
Kinase 88601.m00557.AA CAMK-Unique 83-142 24 0.014976 4.01 In-house 112-190 (363) Show / Hide 
Range on Protein: 83-142
Range on HMM: 112-190/363
Sequence Identity: 24% (20 aa)

ILMDYIPGNTLTKLING---------------------GYVGN--RVKRLYMLEIFAAIAYQLTLMREKGIKHCDLKPDNIVV
|.|.|..|..| ..|.                      |.     .  ...|...  |.||    | ...| | |||..||.|
IVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAY----MHSQDIVHRDLKLENIMV