Gene TVAG_182480 (T.vaginalis)
TVAG_182480
Species: T.vaginalis
Alias: TvagK1053, TVAG_182480
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| TVAG_182480.AA | Protein | None | 2138 | None | Fasta, JSON |
| TVAG_182480.kin_dom | Protein Kinase Domain | None | 258 | None | Fasta, JSON |
Protein domains of TVAG_182480.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | TVAG_182480.AA | FATC | 2106-2138 | 39 | 3.9e-11 | 38.68 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 2106-2138 Range on HMM: 1-33/33 Sequence Identity: 39% (13 aa) TDVSLETELQQLIESATDINNIAKMPPSWYPWW . | | ..||..|||..|...| . | ||| EPLSVEQQVDRLIQEATDPENLCQMYIGWCPWW |
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| Kinase | TVAG_182480.AA | PIKK | 1916-2056 | 22 | 1.4e-10 | 35.09 | In-house | 142-290 (290) | Show / Hide |
Range on Protein: 1916-2056 Range on HMM: 142-290/290 Sequence Identity: 22% (34 aa) VDYSQLSVEDRVNALKNVRKYFEGNELSRAILVTSKDADAWAYRTSHFSSSLGAMSALAFMLGSVDHSPQQFLIDKITGNVTFSSFAG--GSRKQ----- ..|. .. ...| .. . .. . .. . .. |...| .|.... .|. |. . || | |. ..||..|| . |. .| .| MMYQHWPLHEKVEVFREQMQNTPPDMFKKWFWRKFPDPEIWWERRENYTRSYAVMCMVGYILGLGDRHPENIMIDMQTGEIVHIDFGCCFESAMQRLPVP -SVPFRLTPQLSNALGRCQYSGPFSSYFTQTMKDIRKRAISLAPVLQFF ||||||....||.| .. .|.| . ..|. .|. .| |. | EKVPFRLTRNMVNAMGPMGVEGVFRRCCEHVMMCMRQHRETLMTVCEVF |
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| Kinase | TVAG_182480.AA | ATR | 1952-2056 | 21 | 6.4e-09 | 26.09 | In-house | 156-267 (267) | Show / Hide |
Range on Protein: 1952-2056 Range on HMM: 156-267/267 Sequence Identity: 21% (24 aa) DADAWAYRTSHFSSSLGAMSALAFMLGSVDHSPQQFLIDKITGNVTFSSFAGGSRK-------QSVPFRLTPQLSNALGRCQYSGPFSSYFTQTMKDIRK |. | . . | ... . ...| | . |||||.| . .. . |||||| . ...| . | | .|. .|. DPQQWYSSRENYCRSYAVWCMVGYIIGLGDRHTDNILIDKINGECVHVDYNCIFNSGEQFEVPEIVPFRLTHNMVFGMGPMKTYGLFRRACEVIMMCMRD RAISLAPVLQFF . . |.. | HRDDIMSVWDCF |
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| PI3Kc | TVAG_182480.AA | PI3Kc | 1837-2124 | 14 | 2.1e-05 | -80.16 | SMART | 1-336 (336) | Show / Hide |
Range on Protein: 1837-2124
Range on HMM: 1-336/336
Sequence Identity: 14% (49 aa)
RNLKKV-----RSLATEQLVDALTPILDDI-------HHINHGSIIQLSGNLYLFEVPKGQASMYEMITVYEQSKGRIIDAEQASIKKWYNV--------
. . |. . . |.. |. |.. ..| .. . . |. . ... .. |. |. ..| .|. . |
AVIFKCGDDLRQDMRMMQMFRLMNKIWQKDKECRRRDLHMRPYKCIPTGPKCGMIEWVPNCETLHQIQKKYHKWKKMPMDYHQWFMFDML-VPEIQKNMY
-------------DYSQLSVEDRVNALKNVRKYFEGNELSRAILVTSKDAD-AWAYRTSHFSSSLGAMSALAFMLGSVDHSPQQFLIDKITGNV------
.| ... . .. ... | .. | . ...|.. .| . ..| .|. ... ..|| | ......|. ||..
MMIWHQQACHWMMMYQHMTHMEWLKYFEGATCPFKPPVLYDWFWEHFPDPNEDWWEARDNFTRSCAGYCMVTYILGIGDRHNDNIMLDMKTGHCFHIDFG
-TFSSFAGGSRKQ-----SVPFRLTPQLSNALG----RCQYSGPFSSYFTQTMKDIRKRAISLAPVLQFFIADPPFTKPKI-PHSFMKQLGVEIPVEENQ
|... . . ||||||... .. | .| | | .. .... .|| . .. ... .. || | |. |. . | .....
HIFGHGPKKPGFKHHHRERVPFRLTHDMVYVMGGGGKPSGYFGYFRTCCCRAYRAMRKHSNLIMNLFEMMVYDP------IMPCWRMM--EKDIKYLRQR
TQEEKEIDEEINDIYAR-----LVGTD-VSLETELQQLIESATDI
... |||. .. | . . |. |....... .
FRLDHLSDEEAAQYFMQTMCTKLIEHSNESWTTRMYWMFHNWAQY
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| Kinase | TVAG_182480.AA | FRAP | 2010-2066 | 36 | 0.003669 | 7.64 | In-house | 195-251 (251) | Show / Hide |
Range on Protein: 2010-2066 Range on HMM: 195-251/251 Sequence Identity: 36% (21 aa) VPFRLTPQLSNALGRCQYSGPFSSYFTQTMKDIRKRAISLAPVLQFFIADPPFTKPK .||||| | ||. |. | . || || |. || |. || | IPFRLTRMLVNAMEACGIEGNYRNTCELVMKVIREHKESVMAVLEAFVYDPLFYWRL |
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| Kinase | TVAG_182480.AA | FRAP | 1917-1996 | 23 | 0.015532 | 5.31 | In-house | 94-173 (251) | Show / Hide |
Range on Protein: 1917-1996 Range on HMM: 94-173/251 Sequence Identity: 23% (19 aa) DYSQLSVEDRVNALKNVRKYFEGNELSRAILVTSKDADAWAYRTSHFSSSLGAMSALAFMLGSVDHSPQQFLIDKITGNV ||..| ..| . . . |..| . . | . | | . || || ..|| | | .... || . DYDHLPLMNKVEIFRYIMNNTKGEDLKKLLWLKSPNSEIWFERRTNYTRSLATMSMAGYILGLGDRHPSNIMLQRYTGKI |
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