Gene TVAG_193050 (T.vaginalis)
TVAG_193050
Species: T.vaginalis
Alias: TVAG_193050, TvagK1055
External Links:
Annotation:
Group:
TKL
Family:
TKL-Unique
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| TVAG_193050.AA | Protein | None | 645 | None | Fasta, JSON |
| TVAG_193050.kin_dom | Protein Kinase Domain | None | 232 | None | Fasta, JSON |
Protein domains of TVAG_193050.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | TVAG_193050.AA | Dicty4 | 241-275 | 27 | 9.8e-10 | 28.83 | In-house | 241-277 (277) | Show / Hide |
Range on Protein: 241-275 Range on HMM: 241-277/277 Sequence Identity: 27% (10 aa) PANFPNKWAILIVKCLQKNPAERPTIDQICRE--INA |...|..|. ||..|. ..| ||. .| . .. PDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH |
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| Kinase | TVAG_193050.AA | TKL | 208-273 | 20 | 1.8e-08 | 26.67 | In-house | 261-364 (364) | Show / Hide |
Range on Protein: 208-273 Range on HMM: 261-364/364 Sequence Identity: 20% (21 aa) IPKEDISEKFDVYSFGAIVFEILVG-HTYK-------------------------AKSFP------------ANFPNKWAILIVKCLQKNPAERPTIDQI ..... ||| |||||| . .||| . . |. | ..| .. |. .| . .| .||. ..| CKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEI CREI .. LKRL |
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| Kinase | TVAG_193050.AA | DRK | 241-275 | 25 | 3e-07 | 20.65 | In-house | 224-258 (258) | Show / Hide |
Range on Protein: 241-275 Range on HMM: 224-258/258 Sequence Identity: 25% (9 aa) PANFPNKWAILIVKCLQKNPAERPTIDQICREINA |.. | |.. |. |. .| ||. ... . | PQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA |
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| Kinase | TVAG_193050.AA | Dicty4-Unclassified | 241-273 | 39 | 7.1e-07 | 19.55 | In-house | 231-263 (263) | Show / Hide |
Range on Protein: 241-273 Range on HMM: 231-263/263 Sequence Identity: 39% (13 aa) PANFPNKWAILIVKCLQKNPAERPTIDQICREI | | .| | ||. |. | |||..|| PDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL |
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| Kinase | TVAG_193050.AA | NAK-Unclassified | 239-275 | 33 | 1e-06 | 19.02 | In-house | 367-405 (405) | Show / Hide |
Range on Protein: 239-275 Range on HMM: 367-405/405 Sequence Identity: 33% (13 aa) SFPAN--FPNKWAILIVKCLQKNPAERPTIDQICREINA .|| | . |. || ..|. .| .||.| |. .|. EFPSNHNYSNQLHNLIKIMLNEDPIQRPNIYQVLNHICQ |
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| Kinase | TVAG_193050.AA | TK | 218-273 | 17 | 2e-06 | 16.88 | In-house | 376-486 (486) | Show / Hide |
Range on Protein: 218-273 Range on HMM: 376-486/486 Sequence Identity: 17% (19 aa) DVYSFGAIVFEILV-G-HTYKA-KSF------------------------------------P--ANFP--------------NKWAILIVKCLQKNPAE ||.||| ..||. | .| | | .. | ...|. .| ...|.. DVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPED RPTIDQICREI ||| .|. ... RPTFSQLHEQL |
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| Kinase | TVAG_193050.AA | NAK | 238-273 | 28 | 2e-06 | 17.33 | In-house | 262-299 (299) | Show / Hide |
Range on Protein: 238-273 Range on HMM: 262-299/299 Sequence Identity: 28% (11 aa) KSFPAN--FPNKWAILIVKCLQKNPAERPTIDQICREI .|.| | .... || ..|. .| .||.|.|.. . YSIPDNSRYSQQMHDLIRYMLTPDPEQRPNIYQVLNQL |
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| S_TKc | TVAG_193050.AA | S_TKc | 32-279 | 18 | 3e-06 | -85.63 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 32-279 Range on HMM: 1-231/231 Sequence Identity: 18% (52 aa) FNIGPTVERNCFGTVVDVTTVKNGESLSLAFILNLFIDRKNIADPNKFAEKIQQLTQLSHPALIKVIGIVFPGEKNRLHHAIVRENNYI--CDLSSIFEK . |. .. . ||.| .. .| |. . | ... || | . || ..| ... | .| | || .. .| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKK DFIHFKEVEWDNTRKSITIIGLAAALRYLHEKGLYH-------LFLVPWHILF----DSKFEPILDGFYLSSSVAHNQLY--PETTGYDSYIPKEDISE- | . . . . . .. || |.|..| | ..| || ... ... | || . RGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL---------TTFCGTPWYMAPEVL---------GYGKC KFDVYSFGAIVFEILVGHT--------YKAKSFPANFPNKWAILIVKCLQKNPAERPTIDQICR---EINAGVFI | |..|.| |..| |.| . .| . .| |||||.|..|||. .. . .|.. .. KCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | TVAG_193050.AA | TKL-Unique | 211-230 | 55 | 7e-05 | 13.36 | In-house | 203-222 (290) | Show / Hide |
Range on Protein: 211-230 Range on HMM: 203-222/290 Sequence Identity: 55% (11 aa) EDISEKFDVYSFGAIVFEIL ...||| ||||||... ||. CQYSEKSDVYSFGIVLWEIA |
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| Kinase | TVAG_193050.AA | CZAK | 214-230 | 58 | 7.7e-05 | 13.68 | In-house | 200-216 (279) | Show / Hide |
Range on Protein: 214-230 Range on HMM: 200-216/279 Sequence Identity: 58% (10 aa) SEKFDVYSFGAIVFEIL .|| |||||| |...|. TEKVDVYSFGMILWCII |
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| Kinase | TVAG_193050.AA | TKL-Unique | 251-273 | 34 | 0.000112 | 12.62 | In-house | 268-290 (290) | Show / Hide |
Range on Protein: 251-273 Range on HMM: 268-290/290 Sequence Identity: 34% (8 aa) LIVKCLQKNPAERPTIDQICREI || .| .| .||. |.| .. LIQQCWHHDPSQRPSFDEIIHRL |
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| Kinase | TVAG_193050.AA | RAF | 251-273 | 39 | 0.000178 | 11.26 | In-house | 253-275 (275) | Show / Hide |
Range on Protein: 251-273 Range on HMM: 253-275/275 Sequence Identity: 39% (9 aa) LIVKCLQKNPAERPTIDQICREI |.. |. ..| |||. || .| LLMECWSYQPEERPSFQQIMKMI |
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| Kinase | TVAG_193050.AA | Pkinase | 251-273 | 40 | 0.000241 | 16.44 | Pfam | 269-293 (293) | Show / Hide |
Range on Protein: 251-273 Range on HMM: 269-293/293 Sequence Identity: 40% (10 aa) LIVKCLQKNPAERPTIDQICRE--I .| .||.|.|..|||..||. . FIKWCLCKDPKKRPTAEQILQHPWF |
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| TyrKc | TVAG_193050.AA | TyrKc | 62-273 | 11 | 0.00026 | -152.93 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 62-273
Range on HMM: 1-280/280
Sequence Identity: 11% (38 aa)
FILNLFIDR--------------------KNIADPNKFAEKIQQLTQL--SHPALIKVIGIVFPG-----------------EKNRLHHAIVRENNYICD
|. . . |. | | . .. ...| .|| ... .|.. . .. |.. . . .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK---
LSSIFEKDFIHFKEVEWDNTRKSITIIGLAAALRYLHEKGLYHLFLVPWHILFDSKFEPI-----------LDGFY--------LSSSVAHN-------Q
. . . |. .|||.| .. .. . || . . .
----------------LCMKDLLSFCWQIACGMEYLHSK-------------------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKD
LYPETT--GYDS-----YIPKEDI-----SEKFDVYSFGAIVFEIL-VGHTYKAK---------------------SFPAN--------FPNKWAILIVK
| .. | .. . | | ..| ||.||| .||. | . |.| | . .. .
YYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQ
CLQKNPAERPTIDQICREI
| . .|..||| .|....
CWHEDPEDRPTFSEIHECF
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| Kinase | TVAG_193050.AA | CZAK | 241-273 | 36 | 0.000493 | 10.72 | In-house | 244-279 (279) | Show / Hide |
Range on Protein: 241-273 Range on HMM: 244-279/279 Sequence Identity: 36% (13 aa) PANFPNKWA---ILIVKCLQKNPAERPTIDQICREI | .. .| || .| ||| |||. || PQPMDPMWKNLGELIEMCWNKNPDERPSFKQILQHL |
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| Kinase | TVAG_193050.AA | Pkinase_Tyr | 245-273 | 27 | 0.000619 | 13.95 | Pfam | 242-270 (270) | Show / Hide |
Range on Protein: 245-273 Range on HMM: 242-270/270 Sequence Identity: 27% (8 aa) PNKWAILIVKCLQKNPAERPTIDQICREI | . |. .| ...|..||| .| ... PDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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| Kinase | TVAG_193050.AA | RAF | 214-233 | 40 | 0.001069 | 8.56 | In-house | 195-214 (275) | Show / Hide |
Range on Protein: 214-233 Range on HMM: 195-214/275 Sequence Identity: 40% (8 aa) SEKFDVYSFGAIVFEILVGH |.. |||.|| . .|.. |. SFQSDVYAFGTVWYELMAGE |
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| Kinase | TVAG_193050.AA | Dicty4 | 215-230 | 68 | 0.053599 | 2.65 | In-house | 196-211 (277) | Show / Hide |
Range on Protein: 215-230 Range on HMM: 196-211/277 Sequence Identity: 68% (11 aa) EKFDVYSFGAIVFEIL || |||||| . .||| EKADVYSFGIVLWEIL |
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| Kinase | TVAG_193050.AA | DRK | 215-230 | 50 | 0.074311 | 2.11 | In-house | 181-196 (258) | Show / Hide |
Range on Protein: 215-230 Range on HMM: 181-196/258 Sequence Identity: 50% (8 aa) EKFDVYSFGAIVFEIL || |||||. . |.. EKADVYSFAIVLWECV |
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| Kinase | TVAG_193050.AA | Pkinase | 211-234 | 33 | 7.146065 | 0.63 | Pfam | 187-210 (293) | Show / Hide |
Range on Protein: 211-234 Range on HMM: 187-210/293 Sequence Identity: 33% (8 aa) EDISEKFDVYSFGAIVFEILVGHT .... | |..|.| |..| | |.. QYYGPKVDMWSCGCILYEMLCGRP |
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| Sel1 | TVAG_193050.AA | Sel1 | 354-389 | 22 | 4.4e-08 | 29.97 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 354-389 Range on HMM: 1-43/43 Sequence Identity: 22% (10 aa) TDAQFAIA--ARFLEGK--G-VQR-N-PHH-AERFFTLAAEGGN ||.... ...|. | | . . . | .....||| |. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | TVAG_193050.AA | Sel1 | 483-514 | 18 | 0.072298 | 9.34 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 483-514 Range on HMM: 1-43/43 Sequence Identity: 18% (8 aa) SDAQYEYA--L--ALAD----SRR---FTE-ASQYLRLAANAGH . |||... . . .. . . | .....||..|| P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | TVAG_193050.AA | Sel1 | 569-603 | 22 | 0.00047 | 16.6 | Pfam | 1-43 (43) | Show / Hide |
Range on Protein: 569-603 Range on HMM: 1-43/43 Sequence Identity: 22% (10 aa) PIAKYKLG--KMMFDGV----MTR-N-MKD-GVSLMKAAADSGL | | |.|| | ..| .. . . .. ... ||. | P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH |
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| Sel1 | TVAG_193050.AA | Sel1 | 604-630 | 25 | 0.603883 | 6.28 | Pfam | 1-34 (43) | Show / Hide |
Range on Protein: 604-630 Range on HMM: 1-34/43 Sequence Identity: 25% (9 aa) IEAAKDVA--NAYRYGI--G-VPQ-N-IEI-AEAY |. .. .| .|. | ||| . .| | .. P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYW |
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